Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene Gene ontology Other IDs Pathways
Entrez ID	406950
Gene name	MicroRNA 16-1
Gene symbol	MIR16-1
Synonyms (NCBI Gene)	MIRN16-1miRNA16-1mir-16-1
Chromosome	13
Chromosome location	13q14.2
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Show/Hide all (46)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001569	Process	Branching involved in blood vessel morphogenesis	IDA	23083510
GO:0001937	Process	Negative regulation of endothelial cell proliferation	IDA	21885851
GO:0003730	Function	MRNA 3'-UTR binding	IDA	26440600
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0005615	Component	Extracellular space	IDA	20159880
GO:0008285	Process	Negative regulation of cell population proliferation	IGI	22139073
GO:0010666	Process	Positive regulation of cardiac muscle cell apoptotic process	ISS
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IDA	21885851, 23233752
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	15131085, 16166262, 18449891, 19823025, 21532615, 21885851, 22139073, 23083510, 23487264, 25033200, 25261849, 25594541, 25743273, 26440600, 27343180, 27748453
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	23233752
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IGI	25403480
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IDA	21885851
GO:0043065	Process	Positive regulation of apoptotic process	IDA	25261849
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	23487264, 30365148
GO:0045727	Process	Positive regulation of translation	IGI	25403480
GO:0045930	Process	Negative regulation of mitotic cell cycle	ISS
GO:0050728	Process	Negative regulation of inflammatory response	IDA	30365148
GO:0070062	Component	Extracellular exosome	IDA	23233752, 28159509
GO:0071333	Process	Cellular response to glucose stimulus	IDA	30365148
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IDA	27748453
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IMP	23083510
GO:0110081	Process	Negative regulation of placenta blood vessel development	IDA	27748453
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	ISS
GO:1900747	Process	Negative regulation of vascular endothelial growth factor signaling pathway	IDA	21885851
GO:1900747	Process	Negative regulation of vascular endothelial growth factor signaling pathway	IMP	23083510
GO:1901164	Process	Negative regulation of trophoblast cell migration	IMP	23083510
GO:1902430	Process	Negative regulation of amyloid-beta formation	IDA	27343180
GO:1902461	Process	Negative regulation of mesenchymal stem cell proliferation	IMP	23083510
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	HDA	18320040
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	15131085, 16166262, 18449891, 19823025, 21532615, 21885851, 22139073, 23083510, 23233752, 25033200, 25261849, 25594541, 25743273, 26440600, 27343180, 27748453
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	21885851, 27748453
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	IMP	23083510
GO:1904848	Process	Negative regulation of cell chemotaxis to fibroblast growth factor	IDA	23233752
GO:1905205	Process	Positive regulation of connective tissue replacement	ISS
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IDA	25261849
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IGI	21454377
GO:2000134	Process	Negative regulation of G1/S transition of mitotic cell cycle	IMP	23083510
GO:2000545	Process	Negative regulation of endothelial cell chemotaxis to fibroblast growth factor	IDA	21885851
GO:2000752	Process	Regulation of glucosylceramide catabolic process	IGI	25584808
GO:2001027	Process	Negative regulation of endothelial cell chemotaxis	IDA	21885851
GO:2001244	Process	Positive regulation of intrinsic apoptotic signaling pathway	IGI	16166262

MIM	HGNC	e!Ensembl
609704	31545	ENSG00000208006

Interactions View interactions

	KEGG
	MicroRNAs in cancer

MIR16-1 (microRNA 16-1)