MIR145 (microRNA 145)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Pathways Associated diseases
Entrez ID 406937
Gene name MicroRNA 145
Gene symbol MIR145
Synonyms (NCBI Gene)
MIRN145miR-145miRNA145
Chromosome 5
Chromosome location 5q32
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
49
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide all (49)
GO ID Ontology Definition Evidence Reference
GO:0003730 Function MRNA 3'-UTR binding IDA 23076445, 23128394, 26823772, 31150684
GO:0006940 Process Regulation of smooth muscle contraction ISS
GO:0010614 Process Negative regulation of cardiac muscle hypertrophy ISS
GO:0010667 Process Negative regulation of cardiac muscle cell apoptotic process IDA 23028672
GO:0010667 Process Negative regulation of cardiac muscle cell apoptotic process ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Pathways Associated diseases
MIM HGNC e!Ensembl
611795 31532 ENSG00000276365
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Pathways Associated diseases
  KEGG 
  MicroRNAs in cancer  
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
MIR145-related multisystemic smooth muscle dysfunction Uncertain significance rs2481462980 RCV002280373
Show/Hide Text Mining Associations (267)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Abortion Habitual Associate 39941094
Abortion Spontaneous Associate 37373283
Acute Kidney Injury Inhibit 31039814
Adenocarcinoma Associate 25091571, 25551563, 25584614, 26465597
Adenocarcinoma of Lung Associate 21289483, 24026105, 28388536
Adenocarcinoma of Lung Inhibit 26582602
Adenoma Associate 24791633
Adenoma Inhibit 30258124
Adenomyosis Associate 33728345
Albuminuria Associate 36292960