MIR142 (microRNA 142)

Gene

• Entrez ID: 406934
• Gene name: MicroRNA 142
• Gene symbol: MIR142
• Synonyms (NCBI Gene): MIRN142, mir-142
• Chromosome: 17
• Chromosome location: 17q22
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	27277258
GO:0005615	Component	Extracellular space	HDA	18766170, 26646931
GO:0005615	Component	Extracellular space	IDA	25203061
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IGI	26572508
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	26572508
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IMP	24558198
GO:0032496	Process	Response to lipopolysaccharide	ISS	28100738
GO:0032690	Process	Negative regulation of interleukin-1 alpha production	IDA	22870299
GO:0034612	Process	Response to tumor necrosis factor	ISS	28100738
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	22870299, 27277258
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	24558198, 26572508, 31168355
GO:0050728	Process	Negative regulation of inflammatory response	IDA	22870299
GO:0051966	Process	Regulation of synaptic transmission, glutamatergic	IMP	28100738
GO:0051966	Process	Regulation of synaptic transmission, glutamatergic	ISS	28100738
GO:0061890	Process	Positive regulation of astrocyte activation	ISS
GO:0070555	Process	Response to interleukin-1	ISS	28100738
GO:0071560	Process	Cellular response to transforming growth factor beta stimulus	IMP	24558198
GO:0150078	Process	Positive regulation of neuroinflammatory response	ISS	28100738
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	22870299, 24558198, 26572508, 27277258, 31168355
GO:1903347	Process	Negative regulation of bicellular tight junction assembly	IDA	27277258
GO:1903980	Process	Positive regulation of microglial cell activation	ISS
GO:1905710	Process	Positive regulation of membrane permeability	IDA	27277258
GO:2001237	Process	Negative regulation of extrinsic apoptotic signaling pathway	IGI	26572508

Other IDs

• MIM: 615657
• HGNC: 31529
• e!Ensembl: ENSG00000284353

Interactions View interactions