MIR140 (microRNA 140)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Associated diseases
Entrez ID 406932
Gene name MicroRNA 140
Gene symbol MIR140
Synonyms (NCBI Gene)
MIRN140SEDNmiRNA140mir-140
Chromosome 16
Chromosome location 16q22.1
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
35
Gene Gene ontology Other IDs Associated diseases
Show/Hide all (35)
GO ID Ontology Definition Evidence Reference
GO:0003730 Function MRNA 3'-UTR binding IDA 24530397, 24928442, 30233718
GO:0005615 Component Extracellular space HDA 26646931
GO:0010628 Process Positive regulation of gene expression IDA 24530397
GO:0010628 Process Positive regulation of gene expression IDA 27021683
GO:0010629 Process Negative regulation of gene expression IDA 30233718
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Associated diseases
MIM HGNC e!Ensembl
611894 31527 ENSG00000208017
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
Gene Gene ontology Other IDs Associated diseases
Show/Hide Causal Diseases (2)
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Spondyloepiphyseal dysplasia MIR140 type Nishimura Pathogenic rs1567443039 RCV000735792
Spondyloepiphyseal dysplasia, nishimura type Pathogenic rs1567443039 RCV000853066
Show/Hide Text Mining Associations (74)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 35984198
Alzheimer Disease Associate 32846274
Arthritis Associate 27165343
Arthritis Rheumatoid Associate 38241560
Atrial Fibrillation Associate 32244749
Breast Neoplasms Inhibit 23060440, 23752191, 27502506, 29162923
Breast Neoplasms Associate 27959953, 32711415, 34297787, 37378935
Cancer Familial with In Vitro Radioresistance Associate 27102646
Carcinoma Adenoid Cystic Associate 37372400
Carcinoma Ductal Associate 23752191