Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene Gene ontology Other IDs
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	406932
Gene name Gene Name - the full gene name approved by the HGNC.	MicroRNA 140
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MIR140
Synonyms (NCBI Gene) Gene synonyms aliases	MIRN140, SEDN, miRNA140, mir-140
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	24530397, 24928442, 30233718
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0010628	Process	Positive regulation of gene expression	IDA	24530397
GO:0010628	Process	Positive regulation of gene expression	IDA	27021683
GO:0010629	Process	Negative regulation of gene expression	IDA	30233718
GO:0010629	Process	Negative regulation of gene expression	IMP	24928442
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	23401231
GO:0030513	Process	Positive regulation of BMP signaling pathway	IDA	27214554
GO:0032682	Process	Negative regulation of chemokine production	IMP	24928442
GO:0032715	Process	Negative regulation of interleukin-6 production	IDA	30321456
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IDA	30321456
GO:0034144	Process	Negative regulation of toll-like receptor 4 signaling pathway	IGI	30321456
GO:0034144	Process	Negative regulation of toll-like receptor 4 signaling pathway	IMP	30233718
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	23401231, 24530397, 27021683, 29253717, 30233718, 30321456
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	27214554
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	24928442
GO:0042742	Process	Defense response to bacterium	IDA	30321456
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IMP	30233718
GO:0045668	Process	Negative regulation of osteoblast differentiation	IGI	24928442
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IGI	24928442
GO:0071222	Process	Cellular response to lipopolysaccharide	IDA	30321456
GO:0071456	Process	Cellular response to hypoxia	IDA	27021683
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	IDA	30321456
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	HDA	18320040
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	23401231, 24530397, 24928442, 27021683, 27214554, 29253717, 30233718, 30321456
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040
GO:1904646	Process	Cellular response to amyloid-beta	IDA	29253717
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IDA	27021683
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IMP	27214554
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	IMP	27214554
GO:1905461	Process	Positive regulation of vascular associated smooth muscle cell apoptotic process	IDA	27021683
GO:1905932	Process	Positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	IDA	27021683

MIM	HGNC	e!Ensembl
611894	31527	ENSG00000208017

MIR140 (microRNA 140)