MIR132 (microRNA 132)

Gene

• Entrez ID: 406921
• Gene name: MicroRNA 132
• Gene symbol: MIR132
• Synonyms (NCBI Gene): MIRN132, miRNA132, mir-132
• Chromosome: 17
• Chromosome location: 17p13.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005615	Component	Extracellular space	IDA	21868695
GO:0008284	Process	Positive regulation of cell population proliferation	IMP	21868695
GO:0010575	Process	Positive regulation of vascular endothelial growth factor production	ISS
GO:0010628	Process	Positive regulation of gene expression	IDA	24924687, 25217442
GO:0010629	Process	Negative regulation of gene expression	IDA	24924687, 25217442
GO:0016442	Component	RISC complex	IEA
GO:0031393	Process	Negative regulation of prostaglandin biosynthetic process	ISS
GO:0032691	Process	Negative regulation of interleukin-1 beta production	ISS
GO:0032715	Process	Negative regulation of interleukin-6 production	ISS
GO:0032717	Process	Negative regulation of interleukin-8 production	ISS
GO:0032720	Process	Negative regulation of tumor necrosis factor production	ISS
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	24924687, 25217442, 28065883, 28089352
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IMP	21868695
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	20190813
GO:0042632	Process	Cholesterol homeostasis	IDA	24924687
GO:0043524	Process	Negative regulation of neuron apoptotic process	IDA	28089352
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IDA	24924687
GO:0045765	Process	Regulation of angiogenesis	ISS
GO:0045766	Process	Positive regulation of angiogenesis	IMP	21868695
GO:0055089	Process	Fatty acid homeostasis	IDA	24924687
GO:0090050	Process	Positive regulation of cell migration involved in sprouting angiogenesis	IDA	28065883
GO:1900408	Process	Negative regulation of cellular response to oxidative stress	ISS
GO:1901223	Process	Negative regulation of non-canonical NF-kappaB signal transduction	ISS
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	20190813, 24924687, 25217442, 28065883, 28089352
GO:1903589	Process	Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	28065883
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IDA	24924687
GO:1905564	Process	Positive regulation of vascular endothelial cell proliferation	IMP	21868695
GO:2000353	Process	Positive regulation of endothelial cell apoptotic process	IDA	24924687
GO:2001243	Process	Negative regulation of intrinsic apoptotic signaling pathway	ISS

Other IDs

• MIM: 610016
• HGNC: 31516
• e!Ensembl: ENSG00000267200

Interactions View interactions