MIR130A (microRNA 130a)

Gene

• Entrez ID: 406919
• Gene name: MicroRNA 130a
• Gene symbol: MIR130A
• Synonyms (NCBI Gene): MIRN130A, miRNA130A, mir-130a
• Chromosome: 11
• Chromosome location: 11q12.1
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	26398698, 30741461, 31368668
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0010628	Process	Positive regulation of gene expression	IGI	28467929
GO:0010633	Process	Negative regulation of epithelial cell migration	IGI	30741461
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IGI	30741461
GO:0010804	Process	Negative regulation of tumor necrosis factor-mediated signaling pathway	IDA	26435691
GO:0016442	Component	RISC complex	IEA
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IDA	26435691
GO:0032816	Process	Positive regulation of natural killer cell activation	IDA	31883616
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	21067317, 24801815, 24960162, 25681685, 26398698, 26435691, 31368668, 31883616
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IGI	28467929
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	30741461
GO:0043031	Process	Negative regulation of macrophage activation	IMP	26398698
GO:0045766	Process	Positive regulation of angiogenesis	IMP	23136161
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IMP	30741461
GO:0071560	Process	Cellular response to transforming growth factor beta stimulus	IGI	28467929
GO:0098586	Process	Cellular response to virus	IMP	23418453
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	21067317, 24801815, 24960162, 25681685, 26398698, 26435691, 30741461, 31368668, 31883616
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1904187	Process	Regulation of transformation of host cell by virus	IMP	23418453
GO:1904707	Process	Positive regulation of vascular associated smooth muscle cell proliferation	IDA	24960162, 25681685
GO:1905564	Process	Positive regulation of vascular endothelial cell proliferation	IDA	24960162

Other IDs

• MIM: 610175
• HGNC: 31514
• e!Ensembl: ENSG00000208009

Interactions View interactions