MIR125A (microRNA 125a)

Gene

• Entrez ID: 406910
• Gene name: MicroRNA 125a
• Gene symbol: MIR125A
• Synonyms (NCBI Gene): MIRN125A, miRNA125A, mir-125a
• Chromosome: 19
• Chromosome location: 19q13.41
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001960	Process	Negative regulation of cytokine-mediated signaling pathway	ISS	30089723
GO:0003730	Function	MRNA 3'-UTR binding	IDA	30089723
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0010628	Process	Positive regulation of gene expression	IDA	25116893
GO:0010629	Process	Negative regulation of gene expression	IDA	25116893
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IMP	25116893
GO:0032699	Process	Negative regulation of interleukin-16 production	IDA	30089723
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	20190813, 24759737, 26563755, 27252357, 28467514, 30089723
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	22357933
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	30670152
GO:0048665	Process	Neuron fate specification	IMP	22357933
GO:0070062	Component	Extracellular exosome	IDA	27252357
GO:0070104	Process	Negative regulation of interleukin-6-mediated signaling pathway	IGI	30670152
GO:0072125	Process	Negative regulation of glomerular mesangial cell proliferation	IDA	26563755
GO:1900016	Process	Negative regulation of cytokine production involved in inflammatory response	ISS	30089723
GO:1902564	Process	Negative regulation of neutrophil activation	ISS	30089723
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	20190813, 22357933, 26563755, 27252357, 28467514, 30089723, 30670152
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903672	Process	Positive regulation of sprouting angiogenesis	IDA	27252357
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040
GO:1904893	Process	Negative regulation of receptor signaling pathway via STAT	IGI	30670152
GO:1904995	Process	Negative regulation of leukocyte adhesion to vascular endothelial cell	IGI	30670152
GO:2000353	Process	Positive regulation of endothelial cell apoptotic process	IDA	25116893, 28467514

Other IDs

• MIM: 611191
• HGNC: 31505
• e!Ensembl: ENSG00000208008

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer