Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4069
Gene name Gene Name - the full gene name approved by the HGNC.	Lysozyme
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LYZ
Synonyms (NCBI Gene) Gene synonyms aliases	AMYLD5, LYZF1, LZM
Disease Acronyms (UniProt) Disease acronyms from UniProt database	AMYLD5
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q15
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human

Show/Hide all(4)

SNP ID	Visualize variation	Clinical significance	Consequence
rs121913547	T>C	Pathogenic	Coding sequence variant, missense variant
rs121913549	T>A	Pathogenic	Coding sequence variant, missense variant
rs387906535	G>C	Pathogenic	Missense variant, coding sequence variant
rs387906536	T>A,C	Pathogenic	Missense variant, coding sequence variant

Show/Hide all(261)

miRTarBase ID	miRNA	Experiments	Reference
MIRT030049	hsa-miR-26b-5p	Microarray	19088304
MIRT696225	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT696224	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT696223	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT696222	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT696221	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT696220	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT696219	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT696218	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT696217	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT696216	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT696215	hsa-miR-4486	HITS-CLIP	23313552
MIRT696214	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT696213	hsa-miR-661	HITS-CLIP	23313552
MIRT696212	hsa-miR-1273a	HITS-CLIP	23313552
MIRT696211	hsa-miR-4649-5p	HITS-CLIP	23313552
MIRT696210	hsa-miR-6729-5p	HITS-CLIP	23313552
MIRT696209	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT696207	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT696208	hsa-miR-7703	HITS-CLIP	23313552
MIRT696206	hsa-miR-4668-5p	HITS-CLIP	23313552
MIRT696225	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT696216	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT696208	hsa-miR-7703	PAR-CLIP	27292025
MIRT696225	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT696224	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT696223	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT696222	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT696221	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT696220	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT696219	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT696218	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT696217	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT696216	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT696215	hsa-miR-4486	HITS-CLIP	23313552
MIRT696214	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT696213	hsa-miR-661	HITS-CLIP	23313552
MIRT696212	hsa-miR-1273a	HITS-CLIP	23313552
MIRT696211	hsa-miR-4649-5p	HITS-CLIP	23313552
MIRT696210	hsa-miR-6729-5p	HITS-CLIP	23313552
MIRT696209	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT696207	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT696208	hsa-miR-7703	HITS-CLIP	23313552
MIRT696206	hsa-miR-4668-5p	HITS-CLIP	23313552
MIRT1124320	hsa-miR-1268	CLIP-seq
MIRT1124321	hsa-miR-1268b	CLIP-seq
MIRT1124322	hsa-miR-1273	CLIP-seq
MIRT1124323	hsa-miR-1293	CLIP-seq
MIRT1124324	hsa-miR-1827	CLIP-seq
MIRT1124325	hsa-miR-1908	CLIP-seq
MIRT1124326	hsa-miR-2682	CLIP-seq
MIRT1124327	hsa-miR-3122	CLIP-seq
MIRT1124328	hsa-miR-3165	CLIP-seq
MIRT1124329	hsa-miR-3689a-3p	CLIP-seq
MIRT1124330	hsa-miR-3689c	CLIP-seq
MIRT1124331	hsa-miR-3913-5p	CLIP-seq
MIRT1124332	hsa-miR-3929	CLIP-seq
MIRT1124333	hsa-miR-3974	CLIP-seq
MIRT1124334	hsa-miR-4269	CLIP-seq
MIRT1124335	hsa-miR-4419b	CLIP-seq
MIRT1124336	hsa-miR-4433	CLIP-seq
MIRT1124337	hsa-miR-4457	CLIP-seq
MIRT1124338	hsa-miR-4459	CLIP-seq
MIRT1124339	hsa-miR-4478	CLIP-seq
MIRT1124340	hsa-miR-4483	CLIP-seq
MIRT1124341	hsa-miR-449c	CLIP-seq
MIRT1124342	hsa-miR-4514	CLIP-seq
MIRT1124343	hsa-miR-4649-3p	CLIP-seq
MIRT1124344	hsa-miR-4683	CLIP-seq
MIRT1124345	hsa-miR-4692	CLIP-seq
MIRT1124346	hsa-miR-4722-5p	CLIP-seq
MIRT1124347	hsa-miR-4728-5p	CLIP-seq
MIRT1124348	hsa-miR-4742-5p	CLIP-seq
MIRT1124349	hsa-miR-4767	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124351	hsa-miR-4786-5p	CLIP-seq
MIRT1124352	hsa-miR-4793-5p	CLIP-seq
MIRT1124353	hsa-miR-4794	CLIP-seq
MIRT1124354	hsa-miR-485-5p	CLIP-seq
MIRT1124355	hsa-miR-513b	CLIP-seq
MIRT1124356	hsa-miR-513c	CLIP-seq
MIRT1124357	hsa-miR-514b-5p	CLIP-seq
MIRT1124358	hsa-miR-548c-3p	CLIP-seq
MIRT1124359	hsa-miR-622	CLIP-seq
MIRT1124360	hsa-miR-624	CLIP-seq
MIRT1124361	hsa-miR-663	CLIP-seq
MIRT1124362	hsa-miR-766	CLIP-seq
MIRT1124363	hsa-miR-940	CLIP-seq
MIRT1124362	hsa-miR-766	CLIP-seq
MIRT1124322	hsa-miR-1273	CLIP-seq
MIRT1124324	hsa-miR-1827	CLIP-seq
MIRT1124332	hsa-miR-3929	CLIP-seq
MIRT1124335	hsa-miR-4419b	CLIP-seq
MIRT1124339	hsa-miR-4478	CLIP-seq
MIRT1124343	hsa-miR-4649-3p	CLIP-seq
MIRT1124344	hsa-miR-4683	CLIP-seq
MIRT1124346	hsa-miR-4722-5p	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124354	hsa-miR-485-5p	CLIP-seq
MIRT1124362	hsa-miR-766	CLIP-seq
MIRT1124363	hsa-miR-940	CLIP-seq
MIRT1124322	hsa-miR-1273	CLIP-seq
MIRT1124323	hsa-miR-1293	CLIP-seq
MIRT1124324	hsa-miR-1827	CLIP-seq
MIRT1124327	hsa-miR-3122	CLIP-seq
MIRT1124328	hsa-miR-3165	CLIP-seq
MIRT1124329	hsa-miR-3689a-3p	CLIP-seq
MIRT1124330	hsa-miR-3689c	CLIP-seq
MIRT1124331	hsa-miR-3913-5p	CLIP-seq
MIRT1124332	hsa-miR-3929	CLIP-seq
MIRT1124333	hsa-miR-3974	CLIP-seq
MIRT2265556	hsa-miR-4330	CLIP-seq
MIRT1124335	hsa-miR-4419b	CLIP-seq
MIRT1124336	hsa-miR-4433	CLIP-seq
MIRT1124337	hsa-miR-4457	CLIP-seq
MIRT1124338	hsa-miR-4459	CLIP-seq
MIRT1124339	hsa-miR-4478	CLIP-seq
MIRT1124340	hsa-miR-4483	CLIP-seq
MIRT1124343	hsa-miR-4649-3p	CLIP-seq
MIRT1124344	hsa-miR-4683	CLIP-seq
MIRT1124346	hsa-miR-4722-5p	CLIP-seq
MIRT1124347	hsa-miR-4728-5p	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124351	hsa-miR-4786-5p	CLIP-seq
MIRT1124352	hsa-miR-4793-5p	CLIP-seq
MIRT1124353	hsa-miR-4794	CLIP-seq
MIRT1124354	hsa-miR-485-5p	CLIP-seq
MIRT1124355	hsa-miR-513b	CLIP-seq
MIRT1124360	hsa-miR-624	CLIP-seq
MIRT1124362	hsa-miR-766	CLIP-seq
MIRT1124363	hsa-miR-940	CLIP-seq
MIRT2390426	hsa-miR-23a	CLIP-seq
MIRT2390427	hsa-miR-23b	CLIP-seq
MIRT2390428	hsa-miR-23c	CLIP-seq
MIRT1124333	hsa-miR-3974	CLIP-seq
MIRT1124336	hsa-miR-4433	CLIP-seq
MIRT1124337	hsa-miR-4457	CLIP-seq
MIRT1124338	hsa-miR-4459	CLIP-seq
MIRT1124344	hsa-miR-4683	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124351	hsa-miR-4786-5p	CLIP-seq
MIRT1124352	hsa-miR-4793-5p	CLIP-seq
MIRT1124353	hsa-miR-4794	CLIP-seq
MIRT1124355	hsa-miR-513b	CLIP-seq
MIRT1124358	hsa-miR-548c-3p	CLIP-seq
MIRT1124360	hsa-miR-624	CLIP-seq
MIRT2390429	hsa-miR-758	CLIP-seq
MIRT2390430	hsa-miR-944	CLIP-seq
MIRT2453569	hsa-miR-10a	CLIP-seq
MIRT2453570	hsa-miR-10b	CLIP-seq
MIRT1124320	hsa-miR-1268	CLIP-seq
MIRT1124321	hsa-miR-1268b	CLIP-seq
MIRT1124323	hsa-miR-1293	CLIP-seq
MIRT1124325	hsa-miR-1908	CLIP-seq
MIRT1124327	hsa-miR-3122	CLIP-seq
MIRT1124328	hsa-miR-3165	CLIP-seq
MIRT2453571	hsa-miR-339-5p	CLIP-seq
MIRT1124329	hsa-miR-3689a-3p	CLIP-seq
MIRT1124330	hsa-miR-3689c	CLIP-seq
MIRT1124331	hsa-miR-3913-5p	CLIP-seq
MIRT1124333	hsa-miR-3974	CLIP-seq
MIRT2453572	hsa-miR-4421	CLIP-seq
MIRT1124336	hsa-miR-4433	CLIP-seq
MIRT1124337	hsa-miR-4457	CLIP-seq
MIRT1124338	hsa-miR-4459	CLIP-seq
MIRT1124340	hsa-miR-4483	CLIP-seq
MIRT2453573	hsa-miR-4684-5p	CLIP-seq
MIRT1124347	hsa-miR-4728-5p	CLIP-seq
MIRT1124349	hsa-miR-4767	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124355	hsa-miR-513b	CLIP-seq
MIRT1124358	hsa-miR-548c-3p	CLIP-seq
MIRT2453574	hsa-miR-593	CLIP-seq
MIRT1124360	hsa-miR-624	CLIP-seq
MIRT1124361	hsa-miR-663	CLIP-seq
MIRT2453569	hsa-miR-10a	CLIP-seq
MIRT2453570	hsa-miR-10b	CLIP-seq
MIRT1124320	hsa-miR-1268	CLIP-seq
MIRT1124321	hsa-miR-1268b	CLIP-seq
MIRT1124325	hsa-miR-1908	CLIP-seq
MIRT2453571	hsa-miR-339-5p	CLIP-seq
MIRT2453572	hsa-miR-4421	CLIP-seq
MIRT2453573	hsa-miR-4684-5p	CLIP-seq
MIRT1124349	hsa-miR-4767	CLIP-seq
MIRT1124358	hsa-miR-548c-3p	CLIP-seq
MIRT2453574	hsa-miR-593	CLIP-seq
MIRT1124361	hsa-miR-663	CLIP-seq
MIRT2453569	hsa-miR-10a	CLIP-seq
MIRT2453570	hsa-miR-10b	CLIP-seq
MIRT1124320	hsa-miR-1268	CLIP-seq
MIRT1124321	hsa-miR-1268b	CLIP-seq
MIRT1124322	hsa-miR-1273	CLIP-seq
MIRT1124323	hsa-miR-1293	CLIP-seq
MIRT1124324	hsa-miR-1827	CLIP-seq
MIRT1124325	hsa-miR-1908	CLIP-seq
MIRT1124327	hsa-miR-3122	CLIP-seq
MIRT1124328	hsa-miR-3165	CLIP-seq
MIRT2453571	hsa-miR-339-5p	CLIP-seq
MIRT1124329	hsa-miR-3689a-3p	CLIP-seq
MIRT1124330	hsa-miR-3689c	CLIP-seq
MIRT2564912	hsa-miR-371-5p	CLIP-seq
MIRT1124331	hsa-miR-3913-5p	CLIP-seq
MIRT1124332	hsa-miR-3929	CLIP-seq
MIRT1124333	hsa-miR-3974	CLIP-seq
MIRT1124335	hsa-miR-4419b	CLIP-seq
MIRT2453572	hsa-miR-4421	CLIP-seq
MIRT1124336	hsa-miR-4433	CLIP-seq
MIRT1124337	hsa-miR-4457	CLIP-seq
MIRT1124338	hsa-miR-4459	CLIP-seq
MIRT1124339	hsa-miR-4478	CLIP-seq
MIRT1124340	hsa-miR-4483	CLIP-seq
MIRT1124344	hsa-miR-4683	CLIP-seq
MIRT2453573	hsa-miR-4684-5p	CLIP-seq
MIRT1124347	hsa-miR-4728-5p	CLIP-seq
MIRT1124349	hsa-miR-4767	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124351	hsa-miR-4786-5p	CLIP-seq
MIRT1124352	hsa-miR-4793-5p	CLIP-seq
MIRT1124353	hsa-miR-4794	CLIP-seq
MIRT1124354	hsa-miR-485-5p	CLIP-seq
MIRT1124355	hsa-miR-513b	CLIP-seq
MIRT1124358	hsa-miR-548c-3p	CLIP-seq
MIRT2453574	hsa-miR-593	CLIP-seq
MIRT1124360	hsa-miR-624	CLIP-seq
MIRT1124361	hsa-miR-663	CLIP-seq
MIRT1124362	hsa-miR-766	CLIP-seq
MIRT1124363	hsa-miR-940	CLIP-seq
MIRT2453569	hsa-miR-10a	CLIP-seq
MIRT2453570	hsa-miR-10b	CLIP-seq
MIRT1124320	hsa-miR-1268	CLIP-seq
MIRT1124321	hsa-miR-1268b	CLIP-seq
MIRT1124322	hsa-miR-1273	CLIP-seq
MIRT1124323	hsa-miR-1293	CLIP-seq
MIRT1124325	hsa-miR-1908	CLIP-seq
MIRT1124327	hsa-miR-3122	CLIP-seq
MIRT1124328	hsa-miR-3165	CLIP-seq
MIRT2453571	hsa-miR-339-5p	CLIP-seq
MIRT1124329	hsa-miR-3689a-3p	CLIP-seq
MIRT1124330	hsa-miR-3689c	CLIP-seq
MIRT2564912	hsa-miR-371-5p	CLIP-seq
MIRT1124331	hsa-miR-3913-5p	CLIP-seq
MIRT1124333	hsa-miR-3974	CLIP-seq
MIRT2453572	hsa-miR-4421	CLIP-seq
MIRT1124336	hsa-miR-4433	CLIP-seq
MIRT1124337	hsa-miR-4457	CLIP-seq
MIRT1124338	hsa-miR-4459	CLIP-seq
MIRT1124340	hsa-miR-4483	CLIP-seq
MIRT1124344	hsa-miR-4683	CLIP-seq
MIRT2453573	hsa-miR-4684-5p	CLIP-seq
MIRT1124347	hsa-miR-4728-5p	CLIP-seq
MIRT1124349	hsa-miR-4767	CLIP-seq
MIRT1124350	hsa-miR-4768-3p	CLIP-seq
MIRT1124351	hsa-miR-4786-5p	CLIP-seq
MIRT1124352	hsa-miR-4793-5p	CLIP-seq
MIRT1124353	hsa-miR-4794	CLIP-seq
MIRT1124355	hsa-miR-513b	CLIP-seq
MIRT1124358	hsa-miR-548c-3p	CLIP-seq
MIRT2453574	hsa-miR-593	CLIP-seq
MIRT1124360	hsa-miR-624	CLIP-seq
MIRT1124361	hsa-miR-663	CLIP-seq
MIRT1124362	hsa-miR-766	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
SP1	Unknown	15504356

Show/Hide all(22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001895	Process	Retina homeostasis	HEP	23580065
GO:0003796	Function	Lysozyme activity	IBA	21873635
GO:0003796	Function	Lysozyme activity	TAS	2829884
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	HDA	16502470, 22664934, 23580065
GO:0005615	Component	Extracellular space	IDA	21805676
GO:0005615	Component	Extracellular space	TAS	2829884
GO:0006954	Process	Inflammatory response	TAS	366724
GO:0019730	Process	Antimicrobial humoral response	TAS
GO:0019835	Process	Cytolysis	IEA
GO:0031640	Process	Killing of cells of other organism	IDA	9727055
GO:0035578	Component	Azurophil granule lumen	TAS
GO:0035580	Component	Specific granule lumen	TAS
GO:0042742	Process	Defense response to bacterium	IDA	21093056
GO:0042802	Function	Identical protein binding	IPI	23353684
GO:0043312	Process	Neutrophil degranulation	TAS
GO:0044267	Process	Cellular protein metabolic process	TAS
GO:0050829	Process	Defense response to Gram-negative bacterium	IBA	21873635
GO:0050830	Process	Defense response to Gram-positive bacterium	IBA	21873635
GO:0050830	Process	Defense response to Gram-positive bacterium	IDA	21093056
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 23533145
GO:1904724	Component	Tertiary granule lumen	TAS

MIM	HGNC	e!Ensembl
153450	6740	ENSG00000090382

Protein

UniProt ID

P61626

Protein name

Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C)

Protein function

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

PDB

133L , 134L , 1B5U , 1B5V , 1B5W , 1B5X , 1B5Y , 1B5Z , 1B7L , 1B7M , 1B7N , 1B7O , 1B7P , 1B7Q , 1B7R , 1B7S , 1BB3 , 1BB4 , 1BB5 , 1C43 , 1C45 , 1C46 , 1C7P , 1CJ6 , 1CJ7 , 1CJ8 , 1CJ9 , 1CKC , 1CKD , 1CKF , 1CKG , 1CKH , 1D6P , 1D6Q , 1DI3 , 1DI4 , 1DI5 , 1EQ4 , 1EQ5 , 1EQE , 1GAY , 1GAZ , 1GB0 , 1GB2 , 1GB3 , 1GB5 , 1GB6 , 1GB7 , 1GB8 , 1GB9 , 1GBO

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00062	Lys	19 → 146	C-type lysozyme/alpha-lactalbumin family	Domain

Sequence

MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRA
TNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRD
PQGIRAWVAWRNRCQNRDVRQYVQGCGV

Sequence length

148

Interactions

View interactions

	KEGG		Reactome
	Salivary secretion		Neutrophil degranulation Antimicrobial peptides Amyloid fiber formation

Show/Hide Causal Diseases (5)

Disease term	Disease name	dbSNP ID	References
Causal
Amyloidosis	Amyloidosis, familial visceral	rs63750567, rs63750560, rs387906821, rs387906822, rs387906823, rs1561123748, rs140352180, rs770211260, rs763065333, rs1554300664, rs747723062, rs773435101	8464497, 16523055, 1808634, 21988333
Cholestasis	Cholestasis	rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039
Hypertension	Hypertensive disease	rs13306026
Kidney disease	Kidney Diseases	rs74315342, rs749740335, rs757649673, rs112417755, rs35138315
Nephrotic syndrome	Nephrotic Syndrome	rs876657369, rs121912601, rs121912602, rs876657370, rs121912603, rs121912604, rs121912605, rs121907900, rs121907901, rs28941778, rs587776576, rs28942089, rs587776577, rs28941777, rs121907910 View all (152 more)

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
ALys amyloidosis	ALys amyloidosis	GenCC
Inflammatory Bowel Disease	Inflammatory Bowel Disease	GWAS

Show/Hide Text Mining Associations (89)

Disease Name	Relationship Type	References
Associations from Text Mining
AA amyloidosis	Associate	11849445, 16126226, 16441658, 17407782, 20382744, 24747948, 30029603, 33640796, 9010773
Adenoma	Inhibit	12480915
Adenoma	Associate	20002690, 36216310
Alzheimer Disease	Associate	27249223, 27327445
Amniotic Band Syndrome	Associate	27452435
Amyloid Neuropathies Familial	Associate	12675840, 17407782
Amyloidosis	Associate	16126226, 21818368, 28049649, 29455155, 37833900
Amyloidosis Familial	Associate	11849445, 12050338, 12675840, 20382744, 25217048, 29455155, 39511224
Amyloidosis familial visceral	Associate	12675840, 27926837
Aortic Aneurysm Abdominal	Associate	22797469
Arthritis Rheumatoid	Associate	2596882
Autistic Disorder	Associate	40185380
Breast Neoplasms	Associate	12473177
Breast Neoplasms Male	Associate	12473177
Carcinoma Acinar Cell	Associate	27177644
Churg Strauss Syndrome	Stimulate	18263571
Colitis Ulcerative	Stimulate	12519391, 1427374
Colitis Ulcerative	Associate	29556621, 33359089
Coronary Disease	Associate	34692829
Corticobasal Degeneration	Associate	27061067
COVID 19	Associate	37178757
Crohn Disease	Associate	11919217, 34529988
Crohn Disease	Stimulate	12519391, 1427374
Dental Caries	Associate	26161606
Diabetic Nephropathies	Inhibit	24495950
Diabetic Nephropathies	Associate	37656997
Dry Eye Syndromes	Inhibit	22736608
Enterocolitis Necrotizing	Associate	35410162
Facial Dermatoses	Associate	24455724
Fibrosis	Associate	34858345, 38027143
Gastrointestinal Neoplasms	Associate	25217048
Glaucoma Open Angle	Inhibit	37108298
Glioblastoma	Associate	32687679, 33047898
Gout	Associate	35359923
Granulomatosis with Polyangiitis	Associate	21412229
Heart Diseases	Associate	28049649
HIV Infections	Stimulate	37653055
Inflammation	Stimulate	12519391
Inflammation	Inhibit	24495950
Inflammation	Associate	28542447, 30594242, 34858345
Inflammatory Bowel Diseases	Associate	11919217, 1427374, 25217048
Inflammatory Bowel Diseases	Inhibit	24013298
Inflammatory Bowel Diseases	Stimulate	32556182
Intestinal Diseases	Inhibit	12480915
Keratoconus	Associate	21031023
Kidney Diseases	Associate	11849445, 38027143
Kidney Failure Chronic	Associate	34858345
Leukemia Monocytic Acute	Associate	10765922
Leukemia Myeloid Acute	Associate	10889907, 29286103
Leukemia Promyelocytic Acute	Associate	9858224
Leukemia T Cell	Associate	10889907
Lung Diseases Interstitial	Associate	8736208
Lung Neoplasms	Associate	37883760
Lupus Erythematosus Systemic	Stimulate	31019506
Lymphadenitis	Associate	1888450
Lymphoma Large B Cell Diffuse	Associate	37716978
Macular Degeneration	Associate	32974084
Mammary Analogue Secretory Carcinoma	Associate	27177644
Melanoma	Associate	25944800
Metaplasia	Associate	20398667
Multiple Myeloma	Associate	11714920, 14632572, 20382744, 20958028, 23919586, 26884716, 39511224
Multiple Sclerosis	Associate	35049167
Muscular Dystrophy Duchenne	Associate	24190443
Myasthenia Gravis	Associate	35802752
Nasal Polyps	Associate	23709377, 33506054
Neointima	Associate	27926837
Neoplasms	Associate	10656748, 18419622, 27177644, 34189853, 36871023, 9364303
Parkinson Disease	Associate	27061067
Plaque Amyloid	Associate	28049649
Pleural Effusion	Associate	29047238
Prion Diseases	Associate	35359923
Psoriasis	Associate	25332209
Pulmonary Disease Chronic Obstructive	Associate	36655999
Reticular dysgenesis	Associate	32974084
Sarcoidosis	Stimulate	8736208
Sarcoma Myeloid	Associate	14632572, 28574302
Severe Acute Respiratory Syndrome	Stimulate	26161606
Shock	Associate	37614152
Skin Diseases	Associate	25332209
Spondylitis Ankylosing	Stimulate	40591022
Squamous Cell Carcinoma of Head and Neck	Associate	33361747
Stomach Neoplasms	Associate	22133303
Supranuclear Palsy Progressive	Associate	27061067
Synovial Cyst	Associate	2596882
Tauopathies	Associate	27061067
Thrombocythemia Essential	Associate	31801935
Thymoma	Associate	35802752
Tissue Adhesions	Associate	37385390
Ventricular Fibrillation	Associate	23919586

LYZ (lysozyme)