MIR106A (microRNA 106a)

Gene

• Entrez ID: 406899
• Gene name: MicroRNA 106a
• Gene symbol: MIR106A
• Synonyms (NCBI Gene): MIRN106A, mir-106, mir-106a
• Chromosome: X
• Chromosome location: Xq26.2
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	18684319, 23399447, 26265888
GO:0005615	Component	Extracellular space	IDA	26646931
GO:0010628	Process	Positive regulation of gene expression	IMP	23399447
GO:0010629	Process	Negative regulation of gene expression	IMP	23399447
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IGI	22912877
GO:0030514	Process	Negative regulation of BMP signaling pathway	IDA	23399447
GO:0032682	Process	Negative regulation of chemokine production	IDA	23399447
GO:0032693	Process	Negative regulation of interleukin-10 production	IDA	19307576
GO:0032693	Process	Negative regulation of interleukin-10 production	IDA	19307576
GO:0032693	Process	Negative regulation of interleukin-10 production	IMP	19307576
GO:0032693	Process	Negative regulation of interleukin-10 production	IMP	19307576
GO:0032717	Process	Negative regulation of interleukin-8 production	IDA	26265888
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	HDA	18320040
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	19307576, 20190813
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	18684319, 23399447, 23562609
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	22912877, 26265888, 27325313
GO:0042985	Process	Negative regulation of amyloid precursor protein biosynthetic process	IDA	18684319
GO:0045600	Process	Positive regulation of fat cell differentiation	IDA	23399447
GO:0045668	Process	Negative regulation of osteoblast differentiation	IDA	23399447
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	HDA	18320040
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	18684319, 19307576, 20190813, 22912877, 23399447, 23562609, 27325313
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1904046	Process	Negative regulation of vascular endothelial growth factor production	HMP	18320040

Other IDs

• MIM: 300792
• HGNC: 31494
• e!Ensembl: ENSG00000284157

Interactions View interactions