MIR101-1 (microRNA 101-1)

Gene

• Entrez ID: 406893
• Gene name: MicroRNA 101-1
• Gene symbol: MIR101-1
• Synonyms (NCBI Gene): MIRN101-1, mir-101-1
• Chromosome: 1
• Chromosome location: 1p31.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003730	Function	MRNA 3'-UTR binding	IDA	24592211, 30692230
GO:0005615	Component	Extracellular space	HDA	26646931
GO:0010628	Process	Positive regulation of gene expression	IDA	31934175
GO:0010629	Process	Negative regulation of gene expression	IDA	31934175
GO:0010629	Process	Negative regulation of gene expression	IMP	23554480
GO:0016442	Component	RISC complex	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	27693460
GO:0031397	Process	Negative regulation of protein ubiquitination	IDA	24844779
GO:0032691	Process	Negative regulation of interleukin-1 beta production	IMP	26022377
GO:0032715	Process	Negative regulation of interleukin-6 production	IMP	26022377
GO:0032720	Process	Negative regulation of tumor necrosis factor production	IMP	26022377
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	20829195, 23554480, 24592211, 24844779, 25910754, 27693460, 30692230, 31934175
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	21172309, 26022377
GO:0042985	Process	Negative regulation of amyloid precursor protein biosynthetic process	ISS
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IDA	31934175
GO:0050821	Process	Protein stabilization	IDA	24844779
GO:0060354	Process	Negative regulation of cell adhesion molecule production	IDA	23554480, 31934175
GO:0060354	Process	Negative regulation of cell adhesion molecule production	IMP	23554480
GO:0060392	Process	Negative regulation of SMAD protein signal transduction	IDA	27693460
GO:0060546	Process	Negative regulation of necroptotic process	IDA	25910754
GO:0070100	Process	Negative regulation of chemokine-mediated signaling pathway	IDA	27693460
GO:0070555	Process	Response to interleukin-1	ISS
GO:0090050	Process	Positive regulation of cell migration involved in sprouting angiogenesis	IDA	24844779
GO:1901343	Process	Negative regulation of vasculature development	IMP	27693460
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	20829195, 21172309, 23554480, 24592211, 24844779, 25910754, 26022377, 27693460, 30692230, 31934175
GO:1903561	Component	Extracellular vesicle	HDA	28798470
GO:1903589	Process	Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	24844779
GO:2000353	Process	Positive regulation of endothelial cell apoptotic process	IDA	31934175

Other IDs

• MIM: 612511
• HGNC: 31488
• e!Ensembl: ENSG00000199135

Interactions View interactions

Pathways

KEGG:

MicroRNAs in cancer