MIRLET7B (microRNA let-7b)

Gene
Gene Gene ontology Other IDs Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
406884
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA let-7b
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIRLET7B
Synonyms (NCBI Gene) Gene synonyms aliases
LET7B, MIRNLET7B, hsa-let-7b, let-7b
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q13.31
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide all(13)
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 18766170, 26646931
GO:0010507 Process Negative regulation of autophagy IDA 26296645
GO:0034614 Process Cellular response to reactive oxygen species IDA 26296645
GO:0035195 Process Gene silencing by miRNA IDA 15131085, 26296645, 27809873, 28159509
GO:0035195 Process Gene silencing by miRNA IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Pathways Associated diseases
MIM HGNC e!Ensembl
611249 31479 ENSG00000284520
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Pathways Associated diseases
  KEGG  
  MicroRNAs in cancer
Chemical carcinogenesis - receptor activation 		 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Cholestasis Cholestasis rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039 22363424
Show/Hide Text Mining Associations (120)
Associations from Text Mining
Disease Name Relationship Type References
Acute Aortic Syndrome Stimulate 28986538
Adenocarcinoma of Lung Associate 33627711
Adenoma Associate 29112225
Alzheimer Disease Stimulate 30011310
Alzheimer Disease Associate 31377428, 35178230
Ascites Associate 29499737
Asthma Associate 30789054
Atherosclerosis Inhibit 25247304
Bipolar Disorder Associate 40064379
Breast Neoplasms Associate 21826373, 23144930, 23342147, 24983365, 27271599, 31976020, 32894240, 35805995