LY6E (lymphocyte antigen 6 family member E)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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4061 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Lymphocyte antigen 6 family member E |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LY6E |
Synonyms (NCBI Gene)
Gene synonyms aliases
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RIG-E, RIGE, SCA-2, SCA2, TSA-1 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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SCA2 |
Chromosome
Chromosome number
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8 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8q24.3 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q16553 | ||||||||||
Protein name | Lymphocyte antigen 6E (Ly-6E) (Retinoic acid-induced gene E protein) (RIG-E) (Stem cell antigen 2) (SCA-2) (Thymic shared antigen 1) (TSA-1) | ||||||||||
Protein function | GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 p | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed, predominantly in liver, kidney, ovary, spleen and peripheral blood Leukocytes. | ||||||||||
Sequence |
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Sequence length | 131 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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