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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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404672
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Gene name
Gene Name - the full gene name approved by the HGNC.
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General transcription factor IIH subunit 5 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GTF2H5 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTD3, TTDA, bA120J8.2 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q25.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular le |
| UniProt ID |
Q6ZYL4
|
| Protein name |
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8) |
| Protein function |
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA |
| PDB |
1YDL
,
2JNJ
,
5IVW
,
5IY6
,
5IY7
,
5IY8
,
5IY9
,
5OF4
,
6NMI
,
6O9L
,
6O9M
,
6RO4
,
7AD8
,
7EGB
,
7EGC
,
7ENA
,
7ENC
,
7LBM
,
7NVR
,
7NVV
,
7NVW
,
7NVX
,
7NVY
,
7NVZ
,
7NW0
,
8BVW
,
8BYQ
,
8EBS
,
8EBT
,
8EBU
,
8EBV
,
8EBW
,
8EBX
,
8EBY
,
8GXQ
,
8GXS
,
8WAK
,
8WAL
,
8WAN
,
8WAO
,
8WAP
,
8WAQ
,
8WAR
,
8WAS
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| Family and domains |
Pfam
| Accession |
ID |
Position in sequence |
Description |
Type |
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PF06331
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Tfb5 |
1 → 69 |
Transcription factor TFIIH complex subunit Tfb5 |
Family |
|
| Sequence |
|
| Sequence length |
71 |
| Interactions |
View interactions
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