GTF2H5 (general transcription factor IIH subunit 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 404672 |
| Gene name | General transcription factor IIH subunit 5 |
| Gene symbol | GTF2H5 |
| Synonyms (NCBI Gene) |
C6orf175TFB5TFIIHTGF2H5TTDTTD-ATTD3TTDAbA120J8.2
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| Chromosome | 6 |
| Chromosome location | 6q25.3 |
| Summary | This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular le |
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SNPs
SNP information provided by dbSNP.
3
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miRNA
miRNA information provided by mirtarbase database.
704
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q6ZYL4 | ||||||||||
| Protein name | General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8) | ||||||||||
| Protein function | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA | ||||||||||
| PDB | 1YDL , 2JNJ , 5IVW , 5IY6 , 5IY7 , 5IY8 , 5IY9 , 5OF4 , 6NMI , 6O9L , 6O9M , 6RO4 , 7AD8 , 7EGB , 7EGC , 7ENA , 7ENC , 7LBM , 7NVR , 7NVV , 7NVW , 7NVX , 7NVY , 7NVZ , 7NW0 , 8BVW , 8BYQ , 8EBS , 8EBT , 8EBU , 8EBV , 8EBW , 8EBX , 8EBY , 8GXQ , 8GXS , 8WAK , 8WAL , 8WAN , 8WAO , 8WAP , 8WAQ , 8WAR , 8WAS | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 71 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
10
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