Gene Gene information from NCBI Gene database.
Entrez ID 4045
Gene name Limbic system associated membrane protein
Gene symbol LSAMP
Synonyms (NCBI Gene)
IGLON3LAMP
Chromosome 3
Chromosome location 3q13.31
Summary This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adh
miRNA miRNA information provided by mirtarbase database.
924
miRTarBase ID miRNA Experiments Reference
MIRT018263 hsa-miR-335-5p Microarray 18185580
MIRT029724 hsa-miR-26b-5p Microarray 19088304
MIRT628037 hsa-miR-361-3p HITS-CLIP 19536157
MIRT628036 hsa-miR-7110-3p HITS-CLIP 19536157
MIRT628035 hsa-miR-6817-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21982860, 32814053
GO:0005576 Component Extracellular region TAS
GO:0005829 Component Cytosol IDA
GO:0005886 Component Plasma membrane IEA
GO:0005886 Component Plasma membrane TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603241 6705 ENSG00000185565
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q13449
Protein name Limbic system-associated membrane protein (LSAMP) (IgLON family member 3)
Protein function Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hippocampal mossy fiber projection (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07679 I-set 32 128 Immunoglobulin I-set domain Domain
PF13927 Ig_3 131 201 Domain
PF13927 Ig_3 218 294 Domain
Tissue specificity TISSUE SPECIFICITY: Expressed on limbic neurons and fiber tracts as well as in single layers of the superior colliculus, spinal cord and cerebellum.
Sequence
Sequence length 338
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Post-translational modification: synthesis of GPI-anchored proteins