Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	404281
Gene name Gene Name - the full gene name approved by the HGNC.	YY2 transcription factor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	YY2
Synonyms (NCBI Gene) Gene synonyms aliases	ZNF631
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xp22.12
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the t

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miRTarBase ID	miRNA	Experiments	Reference
MIRT643635	hsa-miR-29a-3p	HITS-CLIP	23824327
MIRT643634	hsa-miR-29b-3p	HITS-CLIP	23824327
MIRT643633	hsa-miR-29c-3p	HITS-CLIP	23824327
MIRT643632	hsa-miR-3168	HITS-CLIP	23824327
MIRT643631	hsa-miR-148b-5p	HITS-CLIP	23824327
MIRT643630	hsa-miR-6874-3p	HITS-CLIP	23824327
MIRT643629	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT643628	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT643627	hsa-miR-6871-3p	HITS-CLIP	23824327
MIRT643626	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT643625	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT643624	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT643623	hsa-miR-5682	HITS-CLIP	23824327
MIRT613572	hsa-miR-624-3p	HITS-CLIP	23824327
MIRT613571	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT613570	hsa-miR-4801	HITS-CLIP	23824327
MIRT613569	hsa-miR-4457	HITS-CLIP	23824327
MIRT613568	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT613567	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT613566	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT613565	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT613564	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT613563	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT613562	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT613561	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT613572	hsa-miR-624-3p	HITS-CLIP	23824327
MIRT613571	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT613570	hsa-miR-4801	HITS-CLIP	23824327
MIRT636972	hsa-miR-4714-5p	HITS-CLIP	23824327
MIRT636971	hsa-miR-514a-5p	HITS-CLIP	23824327
MIRT636970	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT613569	hsa-miR-4457	HITS-CLIP	23824327
MIRT636969	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT636968	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT613567	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT613566	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT636967	hsa-miR-200c-5p	HITS-CLIP	23824327
MIRT636966	hsa-miR-550a-3p	HITS-CLIP	23824327
MIRT613561	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT613574	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT613573	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT613572	hsa-miR-624-3p	HITS-CLIP	23824327
MIRT613571	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT613570	hsa-miR-4801	HITS-CLIP	23824327
MIRT613569	hsa-miR-4457	HITS-CLIP	23824327
MIRT613568	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT613567	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT613566	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT613565	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT613564	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT613563	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT613562	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT613561	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT543649	hsa-miR-548ac	PAR-CLIP	21572407
MIRT543650	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT543648	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT543647	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT543646	hsa-miR-548z	PAR-CLIP	21572407
MIRT543645	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT543644	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT543643	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT543642	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT543641	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT543640	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT543639	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT327037	hsa-miR-3646	PAR-CLIP	21572407
MIRT543638	hsa-miR-1252-3p	PAR-CLIP	21572407
MIRT327029	hsa-miR-95-5p	PAR-CLIP	21572407
MIRT643635	hsa-miR-29a-3p	HITS-CLIP	23824327
MIRT643634	hsa-miR-29b-3p	HITS-CLIP	23824327
MIRT643633	hsa-miR-29c-3p	HITS-CLIP	23824327
MIRT643632	hsa-miR-3168	HITS-CLIP	23824327
MIRT643631	hsa-miR-148b-5p	HITS-CLIP	23824327
MIRT643630	hsa-miR-6874-3p	HITS-CLIP	23824327
MIRT643629	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT643628	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT643627	hsa-miR-6871-3p	HITS-CLIP	23824327
MIRT643626	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT643625	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT643624	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT643623	hsa-miR-5682	HITS-CLIP	23824327
MIRT613572	hsa-miR-624-3p	HITS-CLIP	23824327
MIRT613571	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT613570	hsa-miR-4801	HITS-CLIP	23824327
MIRT613569	hsa-miR-4457	HITS-CLIP	23824327
MIRT613568	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT613567	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT613566	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT613565	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT613564	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT613563	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT613562	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT613561	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT613572	hsa-miR-624-3p	HITS-CLIP	23824327
MIRT613571	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT613570	hsa-miR-4801	HITS-CLIP	23824327
MIRT636972	hsa-miR-4714-5p	HITS-CLIP	23824327
MIRT636971	hsa-miR-514a-5p	HITS-CLIP	23824327
MIRT636970	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT613569	hsa-miR-4457	HITS-CLIP	23824327
MIRT636969	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT636968	hsa-miR-550b-3p	HITS-CLIP	23824327
MIRT613567	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT613566	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT636967	hsa-miR-200c-5p	HITS-CLIP	23824327
MIRT636966	hsa-miR-550a-3p	HITS-CLIP	23824327
MIRT613561	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT613574	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT613573	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT613572	hsa-miR-624-3p	HITS-CLIP	23824327
MIRT613571	hsa-miR-4731-3p	HITS-CLIP	23824327
MIRT613570	hsa-miR-4801	HITS-CLIP	23824327
MIRT613569	hsa-miR-4457	HITS-CLIP	23824327
MIRT613568	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT613567	hsa-miR-642a-3p	HITS-CLIP	23824327
MIRT613566	hsa-miR-642b-3p	HITS-CLIP	23824327
MIRT613565	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT613564	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT613563	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT613562	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT613561	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT543649	hsa-miR-548ac	PAR-CLIP	21572407
MIRT543650	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT543648	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT543647	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT543646	hsa-miR-548z	PAR-CLIP	21572407
MIRT543645	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT543644	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT543643	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT543642	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT543641	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT543640	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT543639	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT327037	hsa-miR-3646	PAR-CLIP	21572407
MIRT543638	hsa-miR-1252-3p	PAR-CLIP	21572407
MIRT327029	hsa-miR-95-5p	PAR-CLIP	21572407
MIRT1501378	hsa-miR-1224-3p	CLIP-seq
MIRT1501379	hsa-miR-1234	CLIP-seq
MIRT1501380	hsa-miR-3670	CLIP-seq
MIRT1501381	hsa-miR-371-5p	CLIP-seq
MIRT2150712	hsa-miR-1256	CLIP-seq
MIRT2150713	hsa-miR-3117-5p	CLIP-seq
MIRT2150714	hsa-miR-4642	CLIP-seq
MIRT2150715	hsa-miR-4662a-5p	CLIP-seq
MIRT2150716	hsa-miR-944	CLIP-seq
MIRT2371187	hsa-miR-1200	CLIP-seq
MIRT2150712	hsa-miR-1256	CLIP-seq
MIRT2371188	hsa-miR-1265	CLIP-seq
MIRT2371189	hsa-miR-1910	CLIP-seq
MIRT2371190	hsa-miR-193a-5p	CLIP-seq
MIRT2371191	hsa-miR-3591-5p	CLIP-seq
MIRT2371192	hsa-miR-3677-5p	CLIP-seq
MIRT2371193	hsa-miR-3690	CLIP-seq
MIRT2371194	hsa-miR-3691-3p	CLIP-seq
MIRT2371195	hsa-miR-4251	CLIP-seq
MIRT2371196	hsa-miR-4254	CLIP-seq
MIRT2371197	hsa-miR-4279	CLIP-seq
MIRT2371198	hsa-miR-4329	CLIP-seq
MIRT2371199	hsa-miR-4460	CLIP-seq
MIRT2371200	hsa-miR-4490	CLIP-seq
MIRT2371201	hsa-miR-4695-3p	CLIP-seq
MIRT2371202	hsa-miR-4724-5p	CLIP-seq
MIRT2371203	hsa-miR-4727-3p	CLIP-seq
MIRT2371204	hsa-miR-4742-5p	CLIP-seq
MIRT2371205	hsa-miR-4774-5p	CLIP-seq
MIRT2371206	hsa-miR-520d-5p	CLIP-seq
MIRT2371207	hsa-miR-524-5p	CLIP-seq
MIRT2371208	hsa-miR-7	CLIP-seq
MIRT2371209	hsa-miR-889	CLIP-seq
MIRT2371210	hsa-miR-942	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000987	Function	Cis-regulatory region sequence-specific DNA binding	IDA	16260628
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	15087442
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IDA	16260628
GO:0005634	Component	Nucleus	IEA
GO:0005667	Component	Transcription regulator complex	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IDA	16260628
GO:0008270	Function	Zinc ion binding	IEA
GO:0031519	Component	PcG protein complex	IBA
GO:0043565	Function	Sequence-specific DNA binding	IDA	23332764
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	15087442
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

MIM	HGNC	e!Ensembl
300570	31684	ENSG00000230797

Protein

UniProt ID

O15391

Protein name

Transcription factor YY2 (Yin and yang 2) (YY-2) (Zinc finger protein 631)

Protein function

Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	311 → 335	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	341 → 365	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in kidney, liver, spleen and testis but not in colon. {ECO:0000269|PubMed:15087442}.

Sequence

MASNEDFSITQDLEIPADIVELHDINVEPLPMEDIPTESVQYEDVDGNWIYGGHNHPPLM
VLQPLFTNTGYGDHDQEMLMLQTQEEVVGYCDSDNQLGNDLEDQLALPDSIEDEHFQMTL
ASLSASAASTSTSTQSRSKKPSKKPSGKSATSTEANPAGSSSSLGTRKWEQKQMQVKTLE
GEFSVTMWSPNDNNDQGAVGEGQAENPPDYSEYLKGKKLPPGGLPGIDLSDPKQLAEFTK
VKPKRSKGEPPKTVPCSYSGCEKMFRDYAAMRKHLHIHGPRVHVCAECGKAFLESSKLRR
HQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHLRIHTGDKPFVCPFDVCNRKFAQSTNLKT
HILTHVKTKNNP

Sequence length

372

Interactions

View interactions

	KEGG
	ATP-dependent chromatin remodeling Polycomb repressive complex

YY2 (YY2 transcription factor)