Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	401944
Gene name	Low density lipoprotein receptor class A domain containing 2
Gene symbol	LDLRAD2
Synonyms (NCBI Gene)	-
Chromosome	1
Chromosome location	1p36.12

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miRTarBase ID	miRNA	Experiments	Reference
MIRT496862	hsa-miR-6784-5p	PAR-CLIP	22291592
MIRT496861	hsa-miR-1292-3p	PAR-CLIP	22291592
MIRT496860	hsa-miR-6762-5p	PAR-CLIP	22291592
MIRT496859	hsa-miR-6845-5p	PAR-CLIP	22291592
MIRT495785	hsa-miR-3974	PAR-CLIP	22291592
MIRT495784	hsa-miR-7113-3p	PAR-CLIP	22291592
MIRT495783	hsa-miR-7106-3p	PAR-CLIP	22291592
MIRT496862	hsa-miR-6784-5p	PAR-CLIP	22291592
MIRT496861	hsa-miR-1292-3p	PAR-CLIP	22291592
MIRT496860	hsa-miR-6762-5p	PAR-CLIP	22291592
MIRT496859	hsa-miR-6845-5p	PAR-CLIP	22291592
MIRT495785	hsa-miR-3974	PAR-CLIP	22291592
MIRT495784	hsa-miR-7113-3p	PAR-CLIP	22291592
MIRT495783	hsa-miR-7106-3p	PAR-CLIP	22291592
MIRT1106720	hsa-miR-1224-3p	CLIP-seq
MIRT1106721	hsa-miR-1285	CLIP-seq
MIRT1106722	hsa-miR-1291	CLIP-seq
MIRT1106723	hsa-miR-1299	CLIP-seq
MIRT1106724	hsa-miR-1301	CLIP-seq
MIRT1106725	hsa-miR-1915	CLIP-seq
MIRT1106726	hsa-miR-203	CLIP-seq
MIRT1106727	hsa-miR-3065-3p	CLIP-seq
MIRT1106728	hsa-miR-3187-5p	CLIP-seq
MIRT1106729	hsa-miR-328	CLIP-seq
MIRT1106730	hsa-miR-331-3p	CLIP-seq
MIRT1106731	hsa-miR-3937	CLIP-seq
MIRT1106732	hsa-miR-4291	CLIP-seq
MIRT1106733	hsa-miR-4292	CLIP-seq
MIRT1106734	hsa-miR-4418	CLIP-seq
MIRT1106735	hsa-miR-4436b-5p	CLIP-seq
MIRT1106736	hsa-miR-4493	CLIP-seq
MIRT1106737	hsa-miR-4660	CLIP-seq
MIRT1106738	hsa-miR-4746-5p	CLIP-seq
MIRT1106739	hsa-miR-5047	CLIP-seq
MIRT1106740	hsa-miR-509-3-5p	CLIP-seq
MIRT1106741	hsa-miR-509-5p	CLIP-seq
MIRT1106742	hsa-miR-612	CLIP-seq
MIRT1106743	hsa-miR-875-3p	CLIP-seq
MIRT2029429	hsa-miR-1184	CLIP-seq
MIRT2029430	hsa-miR-1205	CLIP-seq
MIRT2029431	hsa-miR-1972	CLIP-seq
MIRT2029432	hsa-miR-3158-5p	CLIP-seq
MIRT2029433	hsa-miR-4475	CLIP-seq
MIRT2029434	hsa-miR-4715-3p	CLIP-seq
MIRT2029435	hsa-miR-544	CLIP-seq
MIRT2029430	hsa-miR-1205	CLIP-seq
MIRT1106721	hsa-miR-1285	CLIP-seq
MIRT2260342	hsa-miR-1288	CLIP-seq
MIRT1106725	hsa-miR-1915	CLIP-seq
MIRT2260343	hsa-miR-2355-5p	CLIP-seq
MIRT2260344	hsa-miR-298	CLIP-seq
MIRT1106728	hsa-miR-3187-5p	CLIP-seq
MIRT2260345	hsa-miR-3199	CLIP-seq
MIRT1106730	hsa-miR-331-3p	CLIP-seq
MIRT2260346	hsa-miR-3915	CLIP-seq
MIRT2260347	hsa-miR-3928	CLIP-seq
MIRT1106731	hsa-miR-3937	CLIP-seq
MIRT1106733	hsa-miR-4292	CLIP-seq
MIRT1106734	hsa-miR-4418	CLIP-seq
MIRT1106738	hsa-miR-4746-5p	CLIP-seq
MIRT1106740	hsa-miR-509-3-5p	CLIP-seq
MIRT1106741	hsa-miR-509-5p	CLIP-seq
MIRT1106742	hsa-miR-612	CLIP-seq
MIRT1106721	hsa-miR-1285	CLIP-seq
MIRT1106728	hsa-miR-3187-5p	CLIP-seq
MIRT1106742	hsa-miR-612	CLIP-seq
MIRT2029429	hsa-miR-1184	CLIP-seq
MIRT2029430	hsa-miR-1205	CLIP-seq
MIRT2683843	hsa-miR-1286	CLIP-seq
MIRT2683844	hsa-miR-1913	CLIP-seq
MIRT2029432	hsa-miR-3158-5p	CLIP-seq
MIRT2683845	hsa-miR-3189-5p	CLIP-seq
MIRT2683846	hsa-miR-3201	CLIP-seq
MIRT2683847	hsa-miR-324-3p	CLIP-seq
MIRT2683848	hsa-miR-3620	CLIP-seq
MIRT2683849	hsa-miR-4525	CLIP-seq
MIRT2683850	hsa-miR-4716-3p	CLIP-seq
MIRT2683851	hsa-miR-4722-5p	CLIP-seq
MIRT2683852	hsa-miR-4758-3p	CLIP-seq
MIRT2683853	hsa-miR-4779	CLIP-seq
MIRT2683854	hsa-miR-4791	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q5SZI1

Protein name

Low-density lipoprotein receptor class A domain-containing protein 2

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00057	Ldl_recept_a	171 → 213	Low-density lipoprotein receptor domain class A	Repeat

Sequence

MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAP
DTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPP
GAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQ
NGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRSLTPSPAL
GSAGSLWIAAERSSPAGRDPTRQDAALEGSTE

Sequence length

272

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CONNECTIVE TISSUE DISEASES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DYSSEGMENTAL DYSPLASIA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OCULAR HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHWARTZ-JAMPEL SYNDROME	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHWARTZ-JAMPEL SYNDROME, TYPE 1	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

LDLRAD2 (low density lipoprotein receptor class A domain containing 2)