Gene Gene information from NCBI Gene database.
Entrez ID 401505
Gene name Translocase of outer mitochondrial membrane 5
Gene symbol TOMM5
Synonyms (NCBI Gene)
C9orf105Tom5bA613M10.3
Chromosome 9
Chromosome location 9p13.2
miRNA miRNA information provided by mirtarbase database.
251
miRTarBase ID miRNA Experiments Reference
MIRT049947 hsa-miR-30a-5p CLASH 23622248
MIRT041447 hsa-miR-193b-3p CLASH 23622248
MIRT504062 hsa-miR-548m PAR-CLIP 23446348
MIRT504061 hsa-miR-548ag PAR-CLIP 23446348
MIRT504060 hsa-miR-548ai PAR-CLIP 23446348
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
GO ID Ontology Definition Evidence Reference
GO:0005739 Component Mitochondrion HTP 34800366
GO:0005739 Component Mitochondrion IDA
GO:0005739 Component Mitochondrion IEA
GO:0005741 Component Mitochondrial outer membrane IEA
GO:0005741 Component Mitochondrial outer membrane NAS 18331822
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616169 31369 ENSG00000175768
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N4H5
Protein name Mitochondrial import receptor subunit TOM5 homolog
PDB 7CK6 , 7CP9 , 7VBY , 7VC4 , 7VD2 , 7VDD , 8XVA , 9EIH , 9EII , 9EIJ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10642 Tom5 1 50 Mitochondrial import receptor subunit or translocase Family
Sequence
Sequence length 51
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Pink/Parkin Mediated Mitophagy
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
SARCOIDOSIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Carcinoma Hepatocellular Associate 37114494
★☆☆☆☆
Found in Text Mining only
Huntington Disease Associate 38447791
★☆☆☆☆
Found in Text Mining only
Intervertebral Disc Degeneration Associate 38041088
★☆☆☆☆
Found in Text Mining only
Mitochondrial Diseases Stimulate 21467644
★☆☆☆☆
Found in Text Mining only
Obesity Associate 24455749
★☆☆☆☆
Found in Text Mining only