Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	401387
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine rich repeats and death domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LRRD1
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q21.2

Show/Hide all(104)

miRTarBase ID	miRNA	Experiments	Reference
MIRT684732	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT684731	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT684730	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT684729	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT684728	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT684727	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT684726	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT684725	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT684724	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT684723	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT684722	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT684721	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT684720	hsa-miR-302e	HITS-CLIP	23313552
MIRT684719	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT684718	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT684717	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT684716	hsa-miR-520b	HITS-CLIP	23313552
MIRT684715	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT684714	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT684713	hsa-miR-520e	HITS-CLIP	23313552
MIRT684712	hsa-miR-4438	HITS-CLIP	23313552
MIRT684711	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT684710	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT684709	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT684708	hsa-miR-520h	HITS-CLIP	23313552
MIRT684707	hsa-miR-3620-3p	HITS-CLIP	23313552
MIRT684706	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT684705	hsa-miR-6752-3p	HITS-CLIP	23313552
MIRT679261	hsa-miR-6787-3p	HITS-CLIP	23313552
MIRT684704	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT684703	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT684702	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT684701	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT684700	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT684699	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT684698	hsa-miR-5095	HITS-CLIP	23313552
MIRT684697	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT684696	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT684695	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT679264	hsa-miR-2392	HITS-CLIP	23824327
MIRT679263	hsa-miR-340-3p	HITS-CLIP	23824327
MIRT679262	hsa-miR-6827-3p	HITS-CLIP	23824327
MIRT679261	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT679260	hsa-miR-1913	HITS-CLIP	23824327
MIRT679259	hsa-miR-324-3p	HITS-CLIP	23824327
MIRT679258	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT679257	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679256	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679255	hsa-miR-1193	HITS-CLIP	23824327
MIRT679254	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679253	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679252	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT684732	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT684731	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT684730	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT684729	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT684728	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT684727	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT684726	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT684725	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT684724	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT684723	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT684722	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT684721	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT684720	hsa-miR-302e	HITS-CLIP	23313552
MIRT684719	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT684718	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT684717	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT684716	hsa-miR-520b	HITS-CLIP	23313552
MIRT684715	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT684714	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT684713	hsa-miR-520e	HITS-CLIP	23313552
MIRT684712	hsa-miR-4438	HITS-CLIP	23313552
MIRT684711	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT684710	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT684709	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT684708	hsa-miR-520h	HITS-CLIP	23313552
MIRT684707	hsa-miR-3620-3p	HITS-CLIP	23313552
MIRT684706	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT684705	hsa-miR-6752-3p	HITS-CLIP	23313552
MIRT679261	hsa-miR-6787-3p	HITS-CLIP	23313552
MIRT684704	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT684703	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT684702	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT684701	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT684700	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT684699	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT684698	hsa-miR-5095	HITS-CLIP	23313552
MIRT684697	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT684696	hsa-miR-6807-5p	HITS-CLIP	23313552
MIRT684695	hsa-miR-5089-5p	HITS-CLIP	23313552
MIRT679264	hsa-miR-2392	HITS-CLIP	23824327
MIRT679263	hsa-miR-340-3p	HITS-CLIP	23824327
MIRT679262	hsa-miR-6827-3p	HITS-CLIP	23824327
MIRT679261	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT679260	hsa-miR-1913	HITS-CLIP	23824327
MIRT679259	hsa-miR-324-3p	HITS-CLIP	23824327
MIRT679258	hsa-miR-18a-3p	HITS-CLIP	23824327
MIRT679257	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679256	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679255	hsa-miR-1193	HITS-CLIP	23824327
MIRT679254	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679253	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679252	hsa-miR-6848-3p	HITS-CLIP	23824327

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IBA
GO:0007165	Process	Signal transduction	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

A4D1F6

Protein name

Leucine-rich repeat and death domain-containing protein 1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13855	LRR_8	211 → 269	Leucine rich repeat	Repeat
PF13855	LRR_8	257 → 315	Leucine rich repeat	Repeat
PF13855	LRR_8	487 → 545	Leucine rich repeat	Repeat
PF13855	LRR_8	556 → 614	Leucine rich repeat	Repeat

Sequence

MSEKEGMSEVLEDTISQFRKESRSQSMKEPGFIKETSNLINEASDYLEGKSSNQIYETHP
RQNTLESTSSSGRKSKRNEEQKKNLQFSETSTRTGTSQSLSSLTGRTAEYQALVNFLSHE
TVGEVSPQVSEENQKQLGLGADNFTVNLEAKGLQEFPKDILKIKYVKYLYLDKNQIKTFQ
GADSGDLLGLEILSLQENGLSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLF
FYNNYIENFPSDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPKALC
FLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKIKELQLADNK
LEVISHKIENFRELRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTELPKYIHKLNNL
RKLHVNRNNMVKITDCISHLNNICSLEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFP
LGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLDL
GKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKISSDICN
LKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISN
NAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAIYNIF
SLKEINFDDNPLLRPPVEICKGKQLYTIARYLQRADERDEKILEKIFKIVANNITETNFE
FLCQKLNLANSETDMPTKSTVSLSERAHQALVIWKTQSNKLSLTAAALRDQLIRALTMIG
AYEIMDKITALNLFTRAIKF

Sequence length

860

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast Cancer	Breast cancer	N/A	N/A	GWAS

LRRD1 (leucine rich repeats and death domain containing 1)