CCSER1 (coiled-coil serine rich protein 1)

Gene
Gene miRNA Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
401145
Gene name Gene Name - the full gene name approved by the HGNC.
Coiled-coil serine rich protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CCSER1
Synonyms (NCBI Gene) Gene synonyms aliases
FAM190A
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q22.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Other IDs Protein Associated diseases
Show/Hide all(2)
miRTarBase ID miRNA Experiments Reference
MIRT440680 hsa-miR-544a HITS-CLIP 24374217
MIRT440680 hsa-miR-544a HITS-CLIP 24374217
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
618934 29349 ENSG00000184305
Protein
Gene miRNA Other IDs Protein Associated diseases
UniProt ID Q9C0I3
Protein name Serine-rich coiled-coil domain-containing protein 1 (Coiled-coil serine-rich protein 1)
Family and domains
Sequence 
MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRR
SIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFS
SSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKL
LPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGS
SLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNS
AAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSV
SHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIP
TSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDG
NIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDS
YHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNS
PSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVS
PLTEEPVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHLQKAFASRVDKSTQTEL
LCYDGLNLKRLETVQGGREATYRNRIVSQNLSTRDRKAIHTPTEDRFRYSAADQTSPYKN
KTCQLPSLCLSNFLKDKELAEVIKHSRGTYETLTSDVTQNLRATVGQSSLKPTAKTEGLS
TFLEKPKDQVATARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHSTELQTLGQQDG
Sequence length 900
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (13)
Unknown
Disease term Disease name Evidence References Source
Multiple myeloma Multiple myeloma MM cells lacking PSMC6 also developed resistance against Carfilzomib (CAR) GWAS, CBGDA
Neuroticism Neuroticism GWAS
Colorectal Cancer Colorectal Cancer In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. GWAS, CBGDA
Diabetes Diabetes GWAS
Show/Hide Text Mining Associations (8)
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 28990359
Diabetic Nephropathies Associate 33414249
Mesothelioma Malignant Associate 23830731
Neoplasms Associate 23665203
Neoplasms Inhibit 23830731
Pancreatic Neoplasms Associate 23665203
Peripheral Arterial Disease Associate 34601942
Renal Insufficiency Chronic Associate 33414249