Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	401024
Gene name	Fibrous sheath interacting protein 2
Gene symbol	FSIP2
Synonyms (NCBI Gene)	SPGF34
Chromosome	2
Chromosome location	2q32.1
Summary	This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific t

Show/Hide all (2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs773975635	C>-	Pathogenic	Coding sequence variant, frameshift variant
rs1559034750	AATA>-	Pathogenic	Frameshift variant, intron variant, coding sequence variant

128

Show/Hide all (128)

miRTarBase ID	miRNA	Experiments	Reference
MIRT636836	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT636834	hsa-miR-4643	HITS-CLIP	23824327
MIRT636833	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT636832	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT636831	hsa-miR-586	HITS-CLIP	23824327
MIRT636830	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT636829	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT636828	hsa-miR-3941	HITS-CLIP	23824327
MIRT636827	hsa-miR-4672	HITS-CLIP	23824327
MIRT636826	hsa-miR-466	HITS-CLIP	23824327
MIRT636825	hsa-miR-7977	HITS-CLIP	23824327
MIRT636824	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT636823	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT634865	hsa-miR-8060	HITS-CLIP	23824327
MIRT634864	hsa-miR-6841-3p	HITS-CLIP	23824327
MIRT634863	hsa-miR-1915-5p	HITS-CLIP	23824327
MIRT634862	hsa-miR-4641	HITS-CLIP	23824327
MIRT634861	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT634860	hsa-miR-4694-5p	HITS-CLIP	23824327
MIRT634859	hsa-miR-502-5p	HITS-CLIP	23824327
MIRT634858	hsa-miR-7702	HITS-CLIP	23824327
MIRT525523	hsa-miR-583	PAR-CLIP	20371350
MIRT525522	hsa-miR-3125	PAR-CLIP	20371350
MIRT525521	hsa-miR-3916	PAR-CLIP	20371350
MIRT525520	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT525519	hsa-miR-4496	PAR-CLIP	20371350
MIRT525518	hsa-miR-4272	PAR-CLIP	20371350
MIRT525517	hsa-miR-4275	PAR-CLIP	20371350
MIRT525516	hsa-miR-339-5p	PAR-CLIP	20371350
MIRT525513	hsa-miR-6124	PAR-CLIP	20371350
MIRT525510	hsa-miR-4433b-5p	PAR-CLIP	20371350
MIRT525508	hsa-miR-4646-3p	PAR-CLIP	20371350
MIRT525539	hsa-miR-7-1-3p	PAR-CLIP	22012620
MIRT525538	hsa-miR-7-2-3p	PAR-CLIP	22012620
MIRT525537	hsa-miR-651-3p	PAR-CLIP	22012620
MIRT525536	hsa-miR-767-3p	PAR-CLIP	22012620
MIRT525535	hsa-miR-1185-5p	PAR-CLIP	22012620
MIRT525534	hsa-miR-3679-5p	PAR-CLIP	22012620
MIRT525533	hsa-miR-7158-5p	PAR-CLIP	22012620
MIRT525532	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT525531	hsa-miR-6771-3p	PAR-CLIP	22012620
MIRT525530	hsa-miR-8063	PAR-CLIP	22012620
MIRT525529	hsa-miR-4690-3p	PAR-CLIP	22012620
MIRT525528	hsa-miR-5685	PAR-CLIP	22012620
MIRT525527	hsa-miR-6508-5p	PAR-CLIP	22012620
MIRT525526	hsa-miR-8067	PAR-CLIP	22012620
MIRT525525	hsa-miR-6787-3p	PAR-CLIP	22012620
MIRT525524	hsa-miR-6818-3p	PAR-CLIP	22012620
MIRT525523	hsa-miR-583	PAR-CLIP	22012620
MIRT525522	hsa-miR-3125	PAR-CLIP	22012620
MIRT525521	hsa-miR-3916	PAR-CLIP	22012620
MIRT525520	hsa-miR-6859-5p	PAR-CLIP	22012620
MIRT525519	hsa-miR-4496	PAR-CLIP	22012620
MIRT525518	hsa-miR-4272	PAR-CLIP	22012620
MIRT525517	hsa-miR-4275	PAR-CLIP	22012620
MIRT525516	hsa-miR-339-5p	PAR-CLIP	22012620
MIRT525515	hsa-miR-3166	PAR-CLIP	22012620
MIRT525514	hsa-miR-4771	PAR-CLIP	22012620
MIRT525513	hsa-miR-6124	PAR-CLIP	22012620
MIRT525512	hsa-miR-1273h-3p	PAR-CLIP	22012620
MIRT525511	hsa-miR-3678-3p	PAR-CLIP	22012620
MIRT525510	hsa-miR-4433b-5p	PAR-CLIP	22012620
MIRT525509	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT525508	hsa-miR-4646-3p	PAR-CLIP	22012620
MIRT636836	hsa-miR-4789-3p	HITS-CLIP	23824327
MIRT636834	hsa-miR-4643	HITS-CLIP	23824327
MIRT636833	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT636832	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT636831	hsa-miR-586	HITS-CLIP	23824327
MIRT636830	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT636829	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT636828	hsa-miR-3941	HITS-CLIP	23824327
MIRT636827	hsa-miR-4672	HITS-CLIP	23824327
MIRT636826	hsa-miR-466	HITS-CLIP	23824327
MIRT636825	hsa-miR-7977	HITS-CLIP	23824327
MIRT636824	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT636823	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT634865	hsa-miR-8060	HITS-CLIP	23824327
MIRT634864	hsa-miR-6841-3p	HITS-CLIP	23824327
MIRT634863	hsa-miR-1915-5p	HITS-CLIP	23824327
MIRT634862	hsa-miR-4641	HITS-CLIP	23824327
MIRT634861	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT634860	hsa-miR-4694-5p	HITS-CLIP	23824327
MIRT634859	hsa-miR-502-5p	HITS-CLIP	23824327
MIRT634858	hsa-miR-7702	HITS-CLIP	23824327
MIRT525523	hsa-miR-583	PAR-CLIP	20371350
MIRT525522	hsa-miR-3125	PAR-CLIP	20371350
MIRT525521	hsa-miR-3916	PAR-CLIP	20371350
MIRT525520	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT525519	hsa-miR-4496	PAR-CLIP	20371350
MIRT525518	hsa-miR-4272	PAR-CLIP	20371350
MIRT525517	hsa-miR-4275	PAR-CLIP	20371350
MIRT525516	hsa-miR-339-5p	PAR-CLIP	20371350
MIRT525513	hsa-miR-6124	PAR-CLIP	20371350
MIRT525510	hsa-miR-4433b-5p	PAR-CLIP	20371350
MIRT525508	hsa-miR-4646-3p	PAR-CLIP	20371350
MIRT525539	hsa-miR-7-1-3p	PAR-CLIP	22012620
MIRT525538	hsa-miR-7-2-3p	PAR-CLIP	22012620
MIRT525537	hsa-miR-651-3p	PAR-CLIP	22012620
MIRT525536	hsa-miR-767-3p	PAR-CLIP	22012620
MIRT525535	hsa-miR-1185-5p	PAR-CLIP	22012620
MIRT525534	hsa-miR-3679-5p	PAR-CLIP	22012620
MIRT525533	hsa-miR-7158-5p	PAR-CLIP	22012620
MIRT525532	hsa-miR-548as-3p	PAR-CLIP	22012620
MIRT525531	hsa-miR-6771-3p	PAR-CLIP	22012620
MIRT525530	hsa-miR-8063	PAR-CLIP	22012620
MIRT525529	hsa-miR-4690-3p	PAR-CLIP	22012620
MIRT525528	hsa-miR-5685	PAR-CLIP	22012620
MIRT525527	hsa-miR-6508-5p	PAR-CLIP	22012620
MIRT525526	hsa-miR-8067	PAR-CLIP	22012620
MIRT525525	hsa-miR-6787-3p	PAR-CLIP	22012620
MIRT525524	hsa-miR-6818-3p	PAR-CLIP	22012620
MIRT525523	hsa-miR-583	PAR-CLIP	22012620
MIRT525522	hsa-miR-3125	PAR-CLIP	22012620
MIRT525521	hsa-miR-3916	PAR-CLIP	22012620
MIRT525520	hsa-miR-6859-5p	PAR-CLIP	22012620
MIRT525519	hsa-miR-4496	PAR-CLIP	22012620
MIRT525518	hsa-miR-4272	PAR-CLIP	22012620
MIRT525517	hsa-miR-4275	PAR-CLIP	22012620
MIRT525516	hsa-miR-339-5p	PAR-CLIP	22012620
MIRT525515	hsa-miR-3166	PAR-CLIP	22012620
MIRT525514	hsa-miR-4771	PAR-CLIP	22012620
MIRT525513	hsa-miR-6124	PAR-CLIP	22012620
MIRT525512	hsa-miR-1273h-3p	PAR-CLIP	22012620
MIRT525511	hsa-miR-3678-3p	PAR-CLIP	22012620
MIRT525510	hsa-miR-4433b-5p	PAR-CLIP	22012620
MIRT525509	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT525508	hsa-miR-4646-3p	PAR-CLIP	22012620

Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0007288	Process	Sperm axoneme assembly	IMP	30137358, 30745215
GO:0030317	Process	Flagellated sperm motility	IMP	30745215
GO:0061512	Process	Protein localization to cilium	IMP	30137358
GO:0061512	Process	Protein localization to cilium	IMP	30745215
GO:0097225	Component	Sperm midpiece	IDA	30745215
GO:0097228	Component	Sperm principal piece	IMP	30745215
GO:0097229	Component	Sperm end piece	IDA	30745215
GO:0120212	Component	Sperm head-tail coupling apparatus	IDA	30745215

MIM	HGNC	e!Ensembl
615796	21675	ENSG00000188738

Q5CZC0

Protein name

Fibrous sheath-interacting protein 2

Protein function

Plays a role in spermatogenesis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15783	FSIP2	4063 → 4611	Fibrous sheath-interacting protein 2	Family
PF15783	FSIP2	4705 → 4927	Fibrous sheath-interacting protein 2	Family
PF15783	FSIP2	4877 → 5252	Fibrous sheath-interacting protein 2	Family
PF15783	FSIP2	5097 → 5422	Fibrous sheath-interacting protein 2	Family
PF15783	FSIP2	5901 → 6774	Fibrous sheath-interacting protein 2	Family

Tissue specificity

TISSUE SPECIFICITY: Predominantly expressed in testis. {ECO:0000269|PubMed:30137358}.

Sequence

MELYLGACSKPAKVAVTKTVASVLAADTQQCRDGVHKTHFAGVGPAQLLDLPLGVKLPVI
PGSNAVFYTTNFGEKLFRPSYGFNLTDPYCRLLENQYKSLHDPHLKAYYKRKDILKRLKK
GGYITSNNKVVCTLRELNKYRQYLTSLKLDFERNYIKEQRILAKQLHNIPENNQIPQHCD
VAQVQNWLLKEGTESIKDQERLMRHRYLDMISRKLEQLERTAEEQRLFLMDREERRQREH
TRRKLTLRRKIEEEWKTKEMLLLTRMAEDVKREERIEEQQHRNREESDRKKQDLLEKKMA
YHLQKMQDTGFNGEDIGKNTFKYRGQDGTHASPKNKKKTSEDIMLVYPAGDQNTYKETHG
HTANAAHQRQNSSNNFTKKNSASVVYQADVQDNGINQKRDGMVSKNSSIFDDRGGINISG
QGSIISAQVSPTRNFSRVSQAFLDPSKEEKETNADWDGRPTKRSSYLCESGPQAHATDPG
IFSSPVYTNMQQNLLQNCLQEKVTSEELNIIIQNVMTWVVATVTSILYPAITKYEKRLQN
NTYPVSDDSILSSDSSSFCSTCSEDFTYRSYTSATTKTFQAEPCAFVVDTSVRRPTTPIK
PPPAHVEKTVVGKTCHIKGQSIISKHKYNKTNLLYSYPKLRSCKSDSHLLASFETGTKKS
KDATTETDSLGSSLHCDKTAKAMDEMKNLKNVFVNFKCYLKGETEVILESILREIMSDLT
QAIPSLSSVTAEVFVEQCEREKEILLSNAHIPSVASEIVENMLEKLESAVEKKCVEMFSQ
DLSVDIKPSLAASDELLTSSNGKPLKNSMPHTLDPMCDIAEDMVHAILEKLMTLVSFKQN
EFLHLKDTNKLSCQQHKTDPICMFLQRAGKNKSSLESDEASLIVNEEVQNLISNIFSQSS
LVAYIEEAINAILGYIQTELNNERIIASEETVVLLQLLEDILFQLHQEPVNESFQKSRQP
RISSPSDTKEKYRLTGTRLSNSPRSGRPFPPINVPGMVLYSDDENEEIDNIVKNVLDSTF
KDEKVKSQEQIPNHWFTKGNTCFECKRNIKPPTKPGSRSKAAFHDWELKTEPPSTNHEDI
LKKKLSSNKDISTFSQDQKHQIEKASENIVTSILKEMLKDISSVPFGHLDSKTGSEASVL
VSEKPQGLSHQEWIDQMFSVSEISTVAQEITDSVLNILHKASNYISNTTKSSISSSVHQI
SLHNSDTEHIVKEAPNKYPLKTWFDSEKKMKYLSLFDVDPEKPPWLKSGKSEPKPVDDIN
DKIIRTIFKRLKSFICPKLHMGFKSSLRSQLSKYTAKIVNIVLCAIQNELELHKENLNLR
EIDHTKSLTDKGFFANTDKKLESLVTSIDDDILASPLLTCIYDMLLSSENAHQRSISLSS
RKPKSATDSVDVQSILPNRQDKKSFHKYLATPCTHHSVNGGNHIKENAKLQVLERIGETL
HEMLSKLLGTHLHSQLSCSQQSREMTNKNQKMAAALQSNIQLISKAILDYILAKLCGVDM
DTSFASCGLKAISESLDIDNPSFASIIEKMAKSTKIISSIVSRRVQEDNKEETKSKAKPV
APVSSKTPSTKEMHPNKLKAVASDILNMVFAKLEGFANGHLEILGAINDGNKKSNKIGWE
YESTNISRDTHEASFLSALYMHAKKVSSAILKVIQTELNVTSSDLKTSVENPPPETQILK
YVVKLILDAVSSDMFNEMESEGGGIETYRYRPTYGSLPGGAESDSFLEDDAYTAKKIIDE
RSPQREEVKTRSLKQWALEKTLNKIEVKLKEPHISPIAPIIRNILNEIFQSTLINQLNVL
SLSHSNFNGMPHNVDEPTPQTSVQFMDKMMDPLLSEADITIVTDNIVRTVFHKLYSAAMT
ERNVRENRYKTITFSANVSSHEHTYKGKSSVTALDENPCTFQSRFSVADKETKVNLAEDI
VQAILTNLETFATSKVKSLFYSQVNFTVPVALPIQQDHSTLSKALSAKDSYSDEQFSCCS
VDHTKSGKTNLCQLSLSKLNTYALQVARRNLQGIKQELDKERENPFLTHDIGISESIASQ
IVNALLDIISRKGKCDKNSSDKEIDLDQQKGVIEKLLNETKYRKVLQLQIQDTIEGILCD
IYEKTLFQNNLSFATPTLKCSIADKHSEENSEMFMEGANKIIPKLSVPKSDVILISNDIV
NIVLHNLSSAATLVINAKNPTSARLPLTFCDTFPKIDCQQPLKGSKTERKTERFSYSRNQ
KSAYADDNQITVVEKEDTQKSATDSCEENANFITKTIFKRLESFATERIDSLITLAFQSK
EKSFVIPELENCKQNDSIFYDSSQVESDVNVLKISATETILSQELTDFTFVGRREKLGST
IHLSQARLKTYADVIASAILKLIKNDLDLEIQKIYPYQNNILFQENIIVSEIVDSMLKML
DDKRSVKEICFNSKENSNFSQLALSNEILLGHKEKERSTKQSLFTKYPLEQNQMILENKR
QIIVLEEIFMRNGESKNKEKGELLIAVEELLNKLYQRVREVTGHLPPLNETANFISNSKI
KTSDTTQKNSFQSHINSVANDIVESVLGKMYLVVVTSLYENNKSRTEVEISDHNDSLLMK
PLRFRETKQAGKISNSPRYAISQAYSYVDSQNISVMENTLLPYLPLQVKKDLIQMVLNKI
TNFVSLPLKVSPKDNPKPCFKAHLKTRSKITTLPKFTKKTHLGLSAAKAKSKTKLGPGEK
TLKDSRSKTAIGLSHIMSAGDAKNLLDTKLPTSELKIYAKDIIINILETIVKEFGKVKQT
KALPSDQIIAAGKIVNTVLQELYVTNNCNLAYPMKSSHLRLSQGNIGTGSLPKQQACFYL
ENVSSQLEHIFPREGIFKKLFDKWQTESNDKENEKCKLLMIAENVLTEISIKAKELEYSL
SLLNLPPLENCESRFYNHFKGASTRAEDTKAQINMFGREIVEMLLEKLQLCFLSQIPTPD
SEETLSNSKEHITAKSKYGFPNKHSLSSLPIYNTKTKDQISVGSSNQIVQEIVETVLNML
ESFVDLQFKHISKYEFSEIVKMPIENLSSIQQKLLNKKMLPKLQPLKMFSDKSESNTINF
KENIQNILLRVHSFHSQLLTYAVNIISDMLAVIKNKLDNEISQMEPSSISILKENIVASE
IIGTLMDQCTYFNESLIQNLSRESLFQGAENAYTVNQVELATNMKMFTSKLKEGSLGINP
SQVSKTGFVFCSDEDMKEKYRVSSDLPTSVRSSVEDTVKNSEPTKRPDSETMPSCSTRNK
VQDHRPRESNFGSFDQTMKGNSYLPEGSFLQKLLRKASDSTEAALKQVLSFIEMGKGENL
RVFHYENLKPVVEPNQIQTTISPLKICLAAENIVNTVLSSCGFPSQPHTNENREIMKPFF
ISKQSSLSEVSGGQKDNEKSLLRMQDKKINYIPEEENENLEASREDSSFLQKLKKKEYPK
IETVKEVEAFTFADHEMGSNEVHLIARHVTTSVVTYLKNFETTVFSEEKMSVSTWSRKKY
ESKQFLRNIYDDSSIYQCCEHLTESVLYHLTSSISDGTKKGREKEKAWEIQEATFSKIIS
IHSQVFESRSISIGELALCISEIIIKILFNNKIIQADIAQKMVAIPTKYTYCPGIVSGGF
DDLFQDLLVGVIHVLSKEIEVDYHFESNVRNKSFSMHRNNSVPLCNKINRQASPRDWQFS
TQQIGQLFQKNKLSYLACKLNSLVGNLKTSESKEVVNKVFNIVSDLFSPDECLDTGMDSG
KIQRTYFYSSNNEQPNSILTNNLQLSSKSVFLLNVVCEKLIRILLEECTSTAFPDKGSVS
EETSAEECQLLKMLQSVEDGKSDYRKGGMDCECLQVDYMSDLLENVAEIDQDLLTSDSML
TIISHSLVKSLMDKLSHSIQQAPESLPFANKHLNYRTREIQSSFIKARKSELIELGQSKS
SLELRSYDSNSLTVSLNNPSVVSSKIQAPFNKHCAVKSSSVSPFERQRTKEMDKVAIHNK
LHQEGIYAGVYSATFLEGIISELFFNLSMSLWGKNKNITVSWLNEMNTLFVNNVVNEFNN
AQVTVLRNAEERLCFPPVHTETVSKIVDSVYYDVLQQYELKVACGNNPVYDNASIAEQIT
NGILLEILDYKLPSCFKEHLIPHSYYPLKPEIILQKLQSNLTEFTSLPRSSSDYSTMLSH
SFLEDVIRRLLSQLIPPPITCSSLGKKYLMSSDFNEMSTCIINKVMSAISKHKIWFTIYD
NQYLYTGKNLQKMVDSVYCNILQMSDSLVSIQKSIVSRSPIMIDQIASFIIQEIIENHLQ
PFLSGEVLCHPRTPLDPVSTIVTQVLSEVIESHRPQKQSPLDIHLDSFVREIVARLLSKI
FSPKHNTEIELKNMTQRIVNSINRHFNKAKIHILYDDKEQAFFSFNTDIVDELATSVYRN
ALKQHGLDLAVDKESEDSGIFVENITNLIVAAISDYLLHPLFSGDFSASTYSNSVAENIV
QDILSNISKSTEPSQSVPLYNTLLPYTFLEDMIRVLLSKLFSSASSLVLNRDTQKDISRV
NFNDIASNLVSDIRMKVSQHEIRFSKEEEETKFIYSEDDIQHLVDSVFANVVQTSGSQES
AVQNITSSNDILIDRIAGFIIKHICQKHLQPFVSGKSLSSSDTYFDDERRQLFYTSVYSS
TFLEDVISGVLRKIFHRVVGIVQTKSIRDSEDELFEKAEELIHLITGEFSKAQVSIIDNT
EERLCLPPVERDVVKTIVDMVYSKVLQEYEMEVVPNKDFLNDTKTLAARITNIILAEIFD
FQIHPDLIANLPFKSHSKLSANVLIQRVQYDISKSRFQRQASTMYTTMLSHSHLEKIVTQ
LTSQISPLNTSAEQSDTTKSDLSNTVIKLINEIMSIISKHEICIIKYGNKKQSMISAKDI
QSMVDSIYADLSHSNIYQSITKDKKSISDIPVSKIASFIIKEIFNHHIQSFLSEDKTLLL
AAVDQTYKLKAIDPKQRELSFIVNSSVFLEEVISELLCKILYAFSHNMLVTENPDRVKLK
LTRIVTTLVNSIVLEFTTSEILVADNFDKNLCFSERYKEMVQKIVNSVYGKVLDQYKSLI
QIHRVIQSDTICFGRKIYYLLLEEIYDYQVQSLVSGELESSSYSYPQADNIIRNVLNIIT
KDSHALPPYITVLPHSLLEDMVYRLLGHVFPSTHTENELKEKKFPPDDEFVEAASKLTDE
IIKEISEHEIRLSMAEDNAESMQLEPIENLVDSICNNILKTSEFQAEVQKDADKKGCSFL
SKLAGFIMKEIMYHHLQPFLHGEESSFSDLSDYDHVSELAKSGKEKTQPSLYSATFLEDI
IIDLVHKFCSLLIITEDSKKNEMAELDIMGLALKLANSLIREFKKSDIKVLPNAEKMFSF
PPIDKETVDKISNFVYEQFIEKCTSHDIQKGDESNIAIGMIAALTQKAISAFRIQPLFSG
DWSSTFFSFLNPDNITQRVQHLPQNTFTQISRCAKENQLSLPDQSYKDTSSTPDCKNMMS
TLEINRGTMNRKKSFKTKDTSVKKGDIQNPVLSSINAIMKSGMINLTSGLATGVTNKKEV
DENKVGICTQKHSENVSKVTSTTTVKSKDTQEPNLSETFNNNEIEKKRNLIPTDKKGKDD
EIYTHFSLIIDDTEYEKEVLGSDSEIGYKKKIDNARESSFKKDDKLFQLSSLKSKRNLGT
TTDTLEIRIRTSSNEGRRDSPTQTCRDEEHHSDYEHVQNVIENIFEDVLELSSSPEPAYY
SKLSYDQSPPGDNVLNVIQEISRDSAQSVTTKKVSSSTNKNISAKEKEEEEREKEKVREE
IKSEPSKPDDPQNQRESKPGIFPAKFLEDVITEMVKQLIFSSIPETQIQDRCQNVSDKQN
QAKLYDTAMKLINSLLKEFSDAQIKVFRPDKGNQFPGGKVSSVPKVPPRYKEPTTDEAPS
SIKIKSADKMPPMHKMMRKPSSDKIPSIDKTLVNKVVHSSVCNILNDYGSQDSIWKNINS
NGENLARRLTSAVINEIFQRQVNLIFCDEVSVSACLPLESKDVVKKVQKLAQTASKECQT
SSPYTIILPHKFLENVISALFSKIFSTISSTKTKEPEDNLSTELNFLQMKLVSAVATEIS
QDKYMTIQYVETLQSDDDEIIQLVVQSVYNNLLPQFGSQEIIQNCVTSGCKILSENIVDL
VLREVASNQLQSYFCGELTPHQCVEVENIVEKILKDVFQTTDVPLPKPSHADKLSYNIIE
EIAVKFLSKLLSIFPKVHKERTKSLETDMQKITSKVLNSVQEFISKSKIKLVPPTKESPT
VPVADNATIENIVNSIYTSVLKHSGSYTSVFKDLMGKSNVLSDTIGFLMVNAISNSEFQP
QVEEEVSNSELVLEAVKIMEKVIKIIDELKSKEKSSSRKGLTLDAKLLEEVLALFLAKLI
RLPSSSSKDEKNLSKTELNKIASQLSKLVTAEISRSSISLIASDPEEHCLNPENTERIYQ
VVDSVYSNILQQSGTNKEFYYDIKDTNTAFPKKVASLIIDGVSSFPLDTINSTISNADLS
GELDVNRIVQKAQEHAFNVIPELEQEKLDQNLSEEESPIKIVPHVGKKPVKIDPKIISEH
LAVISIKTQPLEKLKQECLKRTGHSIAELRRASISGRNYSLGSPDLEKRKTERRTSLDKT
GRLDVKPLEAVARNSFQNIRKPDITKVELLKDVQSKNDLIVRLVAHDIDQVYLENYIKEE
RDSDEDEVVLTQTFAKEEGIKVFEDQVKEVKKPIQSKLSPKSTLSTSSLKKFLSLSKCCQ
TTASANIESTEAISNQVIESKETHVKRAVAELDMATPKTMPETASSSWEEKPQCKKEEKN
LVTEPTHYFIHRIMSSSSYNQEDLISSTGEAEDCHSDPSAKILEESSQEQKPEHGNSVKF
ITIFERSKDVLGSANPSKEVISETPKPDVSKQGSKMLTKMSSTLSKVFSQCNTNISRSSS
PAHQDEH

Sequence length

6907

Interactions

View interactions

165

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Spermatogenic failure 34	Likely pathogenic; Pathogenic	rs745571898, rs1218883375, rs558463276, rs527302772, rs1325784701, rs2468750474, rs191083003, rs2468764436, rs2468724359, rs1559024613, rs1559034750, rs773975635, rs1559025141	RCV002290258 RCV003324660 RCV003324661 RCV003324662 RCV003324663 RCV003324664 RCV003324665 RCV003324666 RCV003990796 RCV000714283 RCV000714284 RCV000714285 RCV000714286

Show/Hide Unknown Diseases (10)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Likely benign	rs182519742	RCV005933204
Cholangiocarcinoma	Benign	rs77383516	RCV005935201
FSIP2-related disorder	Conflicting classifications of pathogenicity; Likely benign; Uncertain significance; Benign	rs201876794, rs551594235, rs137864187, rs200393690, rs184298485, rs200925453, rs142306380, rs139442712, rs74508015, rs115715789, rs141318533, rs188970608, rs200741240, rs79400482, rs192957612 View all (121 more)	RCV003908517 RCV003898337 RCV003931161 RCV003940986 RCV003941109 RCV003976108 RCV003931348 RCV003903617 RCV003933731 RCV003933732 RCV003971231 RCV003906691 RCV003928993 RCV003966327 RCV004757589 RCV003908925 RCV003954171 RCV003929115 RCV003966391 RCV003908926 RCV003949091 RCV003907118 RCV003907119 RCV003907197 RCV003909474 RCV003907324 RCV003923836 RCV003924137 RCV003981758 RCV003974324 RCV003974350 RCV003974473 RCV003974475 RCV003974579 RCV003974641 RCV003974678 RCV003902310 RCV003974072 RCV003974097 RCV003967354 RCV003967372 RCV003979672 RCV003979731 RCV003979733 RCV003979736 RCV003979744 RCV003984621 RCV003984777 RCV003984788 RCV003982399 RCV003982406 RCV003982413 RCV003982420 RCV003982527 RCV003911765 RCV003911818 RCV003903867 RCV003903945 RCV003903986 RCV003916955 RCV003917024 RCV003964399 RCV003973829 RCV003973914 RCV003964466 RCV003977182 RCV003979462 RCV003982277 RCV003982299 RCV003977298 RCV003977423 RCV003984523 RCV003909746 RCV003914143 RCV003933853 RCV003941977 RCV003952130 RCV003961601 RCV003959558 RCV003972017 RCV003981238 RCV003972096 RCV003917035 RCV003917151 RCV003931507 RCV003931576 RCV003931786 RCV003927103 RCV003929400 RCV003941407 RCV003939705 RCV003939723 RCV003949568 RCV003961449 RCV003914364 RCV003914410 RCV003914444 RCV003914498 RCV003914541 RCV003914604 RCV003924318 RCV003951561 RCV003954765 RCV003954784 RCV003957088 RCV003969250 RCV003922129 RCV003924292 RCV003932201 RCV003932218 RCV003934179 RCV003924690 RCV003954326 RCV003954413 RCV003954664 RCV003972320 RCV003979084 RCV003979168 RCV003964777 RCV003981864 RCV003981883 RCV003981943 RCV003981949 RCV003982082 RCV003982216 RCV003971594 RCV003976512 RCV003972237 RCV003972252 RCV003964244 RCV003981312 RCV003981319 RCV003976339 RCV003972206 RCV004757624 RCV004757625 RCV003936135
Long QT syndrome	Likely benign	rs796052180	RCV000190187
Lung cancer	Benign	rs191655821	RCV005936872
Malignant tumor of esophagus	Likely benign	rs76914767	RCV005937332
Sarcoma	Benign	rs192275221, rs77383516	RCV005935174 RCV005935199
Thymoma	Likely benign; Benign	rs182519742, rs77383516	RCV005933205 RCV005935200
Thyroid cancer, nonmedullary, 1	Likely benign	rs368342499	RCV005931181
Uterine corpus endometrial carcinoma	Benign	rs77383516	RCV005935202

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Azoospermia Nonobstructive	Associate	36017582
Breast Neoplasms	Associate	28027327
Carcinoma Renal Cell	Associate	33162809
Neoplasm Metastasis	Associate	33162809
Paget's Disease Mammary	Associate	30905357
Stomach Neoplasms	Associate	36484990, 36970058
Testicular Germ Cell Tumor	Associate	25609015

FSIP2 (fibrous sheath interacting protein 2)