Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4001
Gene name Gene Name - the full gene name approved by the HGNC.	Lamin B1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LMNB1
Synonyms (NCBI Gene) Gene synonyms aliases	ADLD, ADLDAT, LMN, LMN2, LMNB, MCPH26
Disease Acronyms (UniProt) Disease acronyms from UniProt database	ADLDAT, MCPH26
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q23.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript varian

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002510	hsa-miR-373-3p	Microarray	15685193
MIRT002510	hsa-miR-373-3p	Microarray;Other	15685193
MIRT022094	hsa-miR-128-3p	Sequencing	20371350
MIRT002571	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT002571	hsa-miR-124-3p	Microarray	15685193
MIRT023965	hsa-miR-1-3p	Proteomics	18668040
MIRT024320	hsa-miR-215-5p	Microarray	19074876
MIRT026682	hsa-miR-192-5p	Microarray	19074876
MIRT027335	hsa-miR-101-3p	Sequencing	20371350
MIRT029849	hsa-miR-26b-5p	Microarray	19088304
MIRT044805	hsa-miR-320a	CLASH	23622248
MIRT042270	hsa-miR-484	CLASH	23622248
MIRT041285	hsa-miR-193b-3p	CLASH	23622248
MIRT702258	hsa-miR-4282	HITS-CLIP	23313552
MIRT702257	hsa-miR-3606-3p	HITS-CLIP	23313552
MIRT702256	hsa-miR-513a-3p	HITS-CLIP	23313552
MIRT702255	hsa-miR-513c-3p	HITS-CLIP	23313552
MIRT702254	hsa-miR-154-5p	HITS-CLIP	23313552
MIRT702253	hsa-miR-1248	HITS-CLIP	23313552
MIRT702252	hsa-miR-138-2-3p	HITS-CLIP	23313552
MIRT094815	hsa-miR-600	HITS-CLIP	23313552
MIRT702251	hsa-miR-4297	HITS-CLIP	23313552
MIRT702250	hsa-miR-5581-5p	HITS-CLIP	23313552
MIRT094817	hsa-miR-889-3p	HITS-CLIP	23313552
MIRT702249	hsa-miR-520d-5p	HITS-CLIP	23313552
MIRT702248	hsa-miR-524-5p	HITS-CLIP	23313552
MIRT702247	hsa-miR-7159-3p	HITS-CLIP	23313552
MIRT702246	hsa-miR-4482-3p	HITS-CLIP	23313552
MIRT574200	hsa-miR-3928-3p	PAR-CLIP	20371350
MIRT574199	hsa-miR-3915	PAR-CLIP	20371350
MIRT574198	hsa-miR-1224-5p	PAR-CLIP	20371350
MIRT574197	hsa-miR-4689	PAR-CLIP	20371350
MIRT574196	hsa-miR-6858-5p	PAR-CLIP	20371350
MIRT574195	hsa-miR-1304-5p	PAR-CLIP	20371350
MIRT574194	hsa-miR-8055	PAR-CLIP	20371350
MIRT566917	hsa-miR-218-5p	PAR-CLIP	20371350
MIRT002571	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT566915	hsa-miR-506-3p	PAR-CLIP	20371350
MIRT562010	hsa-miR-23b-3p	PAR-CLIP	20371350
MIRT562011	hsa-miR-23a-3p	PAR-CLIP	20371350
MIRT562009	hsa-miR-23c	PAR-CLIP	20371350
MIRT562012	hsa-miR-130a-5p	PAR-CLIP	20371350
MIRT121611	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT121612	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT311425	hsa-miR-4753-5p	PAR-CLIP	20371350
MIRT311420	hsa-miR-15a-3p	PAR-CLIP	20371350
MIRT566914	hsa-miR-3163	PAR-CLIP	20371350
MIRT566913	hsa-miR-4778-5p	PAR-CLIP	20371350
MIRT566912	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT311421	hsa-miR-10b-3p	PAR-CLIP	20371350
MIRT566911	hsa-miR-6889-3p	PAR-CLIP	20371350
MIRT566910	hsa-miR-5008-3p	PAR-CLIP	20371350
MIRT566909	hsa-miR-6737-3p	PAR-CLIP	20371350
MIRT566908	hsa-miR-7157-3p	PAR-CLIP	20371350
MIRT214144	hsa-miR-4660	PAR-CLIP	20371350
MIRT311423	hsa-miR-4529-5p	PAR-CLIP	20371350
MIRT566907	hsa-miR-636	PAR-CLIP	20371350
MIRT214146	hsa-miR-7156-3p	PAR-CLIP	20371350
MIRT214143	hsa-miR-1301-3p	PAR-CLIP	20371350
MIRT214145	hsa-miR-5047	PAR-CLIP	20371350
MIRT562008	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT214147	hsa-miR-30a-3p	PAR-CLIP	20371350
MIRT214148	hsa-miR-30d-3p	PAR-CLIP	20371350
MIRT214149	hsa-miR-30e-3p	PAR-CLIP	20371350
MIRT121611	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT311421	hsa-miR-10b-3p	PAR-CLIP	20371350
MIRT214144	hsa-miR-4660	PAR-CLIP	20371350
MIRT562012	hsa-miR-130a-5p	PAR-CLIP	20371350
MIRT562011	hsa-miR-23a-3p	PAR-CLIP	20371350
MIRT562010	hsa-miR-23b-3p	PAR-CLIP	20371350
MIRT562009	hsa-miR-23c	PAR-CLIP	20371350
MIRT214146	hsa-miR-7156-3p	PAR-CLIP	20371350
MIRT214143	hsa-miR-1301-3p	PAR-CLIP	20371350
MIRT214145	hsa-miR-5047	PAR-CLIP	20371350
MIRT562008	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT094805	hsa-miR-3123	PAR-CLIP	21572407
MIRT094809	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT094806	hsa-miR-3919	PAR-CLIP	21572407
MIRT214151	hsa-miR-3065-3p	PAR-CLIP	21572407
MIRT094810	hsa-miR-5186	PAR-CLIP	21572407
MIRT357076	hsa-miR-8086	PAR-CLIP	21572407
MIRT094804	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT094808	hsa-miR-4709-3p	PAR-CLIP	21572407
MIRT357075	hsa-miR-449c-3p	PAR-CLIP	21572407
MIRT547582	hsa-miR-6083	PAR-CLIP	21572407
MIRT094805	hsa-miR-3123	PAR-CLIP	21572407
MIRT094809	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT094806	hsa-miR-3919	PAR-CLIP	21572407
MIRT214151	hsa-miR-3065-3p	PAR-CLIP	21572407
MIRT094810	hsa-miR-5186	PAR-CLIP	21572407
MIRT094804	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT094808	hsa-miR-4709-3p	PAR-CLIP	21572407
MIRT547582	hsa-miR-6083	PAR-CLIP	21572407
MIRT536279	hsa-miR-3667-5p	PAR-CLIP	22012620
MIRT513408	hsa-miR-200b-3p	PAR-CLIP	22012620
MIRT513407	hsa-miR-200c-3p	PAR-CLIP	22012620
MIRT513406	hsa-miR-429	PAR-CLIP	22012620
MIRT513405	hsa-miR-4724-5p	PAR-CLIP	22012620
MIRT513404	hsa-miR-4766-5p	PAR-CLIP	22012620
MIRT513408	hsa-miR-200b-3p	PAR-CLIP	23446348
MIRT513407	hsa-miR-200c-3p	PAR-CLIP	23446348
MIRT513406	hsa-miR-429	PAR-CLIP	23446348
MIRT513405	hsa-miR-4724-5p	PAR-CLIP	23446348
MIRT513404	hsa-miR-4766-5p	PAR-CLIP	23446348
MIRT702258	hsa-miR-4282	HITS-CLIP	23313552
MIRT702257	hsa-miR-3606-3p	HITS-CLIP	23313552
MIRT702256	hsa-miR-513a-3p	HITS-CLIP	23313552
MIRT702255	hsa-miR-513c-3p	HITS-CLIP	23313552
MIRT702254	hsa-miR-154-5p	HITS-CLIP	23313552
MIRT702253	hsa-miR-1248	HITS-CLIP	23313552
MIRT702252	hsa-miR-138-2-3p	HITS-CLIP	23313552
MIRT094815	hsa-miR-600	HITS-CLIP	23313552
MIRT702251	hsa-miR-4297	HITS-CLIP	23313552
MIRT702250	hsa-miR-5581-5p	HITS-CLIP	23313552
MIRT094817	hsa-miR-889-3p	HITS-CLIP	23313552
MIRT702249	hsa-miR-520d-5p	HITS-CLIP	23313552
MIRT702248	hsa-miR-524-5p	HITS-CLIP	23313552
MIRT702247	hsa-miR-7159-3p	HITS-CLIP	23313552
MIRT702246	hsa-miR-4482-3p	HITS-CLIP	23313552
MIRT574200	hsa-miR-3928-3p	PAR-CLIP	20371350
MIRT574199	hsa-miR-3915	PAR-CLIP	20371350
MIRT574198	hsa-miR-1224-5p	PAR-CLIP	20371350
MIRT574197	hsa-miR-4689	PAR-CLIP	20371350
MIRT574196	hsa-miR-6858-5p	PAR-CLIP	20371350
MIRT574195	hsa-miR-1304-5p	PAR-CLIP	20371350
MIRT574194	hsa-miR-8055	PAR-CLIP	20371350
MIRT566917	hsa-miR-218-5p	PAR-CLIP	20371350
MIRT002571	hsa-miR-124-3p	PAR-CLIP	20371350
MIRT566915	hsa-miR-506-3p	PAR-CLIP	20371350
MIRT562010	hsa-miR-23b-3p	PAR-CLIP	20371350
MIRT562011	hsa-miR-23a-3p	PAR-CLIP	20371350
MIRT562009	hsa-miR-23c	PAR-CLIP	20371350
MIRT562012	hsa-miR-130a-5p	PAR-CLIP	20371350
MIRT121611	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT121612	hsa-miR-651-3p	PAR-CLIP	20371350
MIRT311425	hsa-miR-4753-5p	PAR-CLIP	20371350
MIRT311420	hsa-miR-15a-3p	PAR-CLIP	20371350
MIRT566914	hsa-miR-3163	PAR-CLIP	20371350
MIRT566913	hsa-miR-4778-5p	PAR-CLIP	20371350
MIRT566912	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT311421	hsa-miR-10b-3p	PAR-CLIP	20371350
MIRT566911	hsa-miR-6889-3p	PAR-CLIP	20371350
MIRT566910	hsa-miR-5008-3p	PAR-CLIP	20371350
MIRT566909	hsa-miR-6737-3p	PAR-CLIP	20371350
MIRT566908	hsa-miR-7157-3p	PAR-CLIP	20371350
MIRT214144	hsa-miR-4660	PAR-CLIP	20371350
MIRT311423	hsa-miR-4529-5p	PAR-CLIP	20371350
MIRT566907	hsa-miR-636	PAR-CLIP	20371350
MIRT214146	hsa-miR-7156-3p	PAR-CLIP	20371350
MIRT214143	hsa-miR-1301-3p	PAR-CLIP	20371350
MIRT214145	hsa-miR-5047	PAR-CLIP	20371350
MIRT562008	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT214147	hsa-miR-30a-3p	PAR-CLIP	20371350
MIRT214148	hsa-miR-30d-3p	PAR-CLIP	20371350
MIRT214149	hsa-miR-30e-3p	PAR-CLIP	20371350
MIRT121611	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT311421	hsa-miR-10b-3p	PAR-CLIP	20371350
MIRT214144	hsa-miR-4660	PAR-CLIP	20371350
MIRT562012	hsa-miR-130a-5p	PAR-CLIP	20371350
MIRT562011	hsa-miR-23a-3p	PAR-CLIP	20371350
MIRT562010	hsa-miR-23b-3p	PAR-CLIP	20371350
MIRT562009	hsa-miR-23c	PAR-CLIP	20371350
MIRT214146	hsa-miR-7156-3p	PAR-CLIP	20371350
MIRT214143	hsa-miR-1301-3p	PAR-CLIP	20371350
MIRT214145	hsa-miR-5047	PAR-CLIP	20371350
MIRT562008	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT094805	hsa-miR-3123	PAR-CLIP	21572407
MIRT094809	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT094806	hsa-miR-3919	PAR-CLIP	21572407
MIRT214151	hsa-miR-3065-3p	PAR-CLIP	21572407
MIRT094810	hsa-miR-5186	PAR-CLIP	21572407
MIRT357076	hsa-miR-8086	PAR-CLIP	21572407
MIRT094804	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT094808	hsa-miR-4709-3p	PAR-CLIP	21572407
MIRT357075	hsa-miR-449c-3p	PAR-CLIP	21572407
MIRT547582	hsa-miR-6083	PAR-CLIP	21572407
MIRT094805	hsa-miR-3123	PAR-CLIP	21572407
MIRT094809	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT094806	hsa-miR-3919	PAR-CLIP	21572407
MIRT214151	hsa-miR-3065-3p	PAR-CLIP	21572407
MIRT094810	hsa-miR-5186	PAR-CLIP	21572407
MIRT094804	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT094808	hsa-miR-4709-3p	PAR-CLIP	21572407
MIRT547582	hsa-miR-6083	PAR-CLIP	21572407
MIRT536279	hsa-miR-3667-5p	PAR-CLIP	22012620
MIRT513408	hsa-miR-200b-3p	PAR-CLIP	22012620
MIRT513407	hsa-miR-200c-3p	PAR-CLIP	22012620
MIRT513406	hsa-miR-429	PAR-CLIP	22012620
MIRT513405	hsa-miR-4724-5p	PAR-CLIP	22012620
MIRT513404	hsa-miR-4766-5p	PAR-CLIP	22012620
MIRT513408	hsa-miR-200b-3p	PAR-CLIP	23446348
MIRT513407	hsa-miR-200c-3p	PAR-CLIP	23446348
MIRT513406	hsa-miR-429	PAR-CLIP	23446348
MIRT513405	hsa-miR-4724-5p	PAR-CLIP	23446348
MIRT513404	hsa-miR-4766-5p	PAR-CLIP	23446348
MIRT1111736	hsa-miR-154	CLIP-seq
MIRT1111737	hsa-miR-2053	CLIP-seq
MIRT1111738	hsa-miR-2113	CLIP-seq
MIRT1111739	hsa-miR-3140-3p	CLIP-seq
MIRT1111740	hsa-miR-3185	CLIP-seq
MIRT1111741	hsa-miR-3190	CLIP-seq
MIRT1111742	hsa-miR-3675-5p	CLIP-seq
MIRT1111743	hsa-miR-3679-3p	CLIP-seq
MIRT1111744	hsa-miR-3925-5p	CLIP-seq
MIRT1111745	hsa-miR-3976	CLIP-seq
MIRT1111746	hsa-miR-4446-5p	CLIP-seq
MIRT1111747	hsa-miR-4469	CLIP-seq
MIRT1111748	hsa-miR-4503	CLIP-seq
MIRT1111749	hsa-miR-4666-5p	CLIP-seq
MIRT1111750	hsa-miR-4704-5p	CLIP-seq
MIRT1111751	hsa-miR-4752	CLIP-seq
MIRT1111752	hsa-miR-4777-5p	CLIP-seq
MIRT1111753	hsa-miR-4802-3p	CLIP-seq
MIRT1111754	hsa-miR-486-3p	CLIP-seq
MIRT1111755	hsa-miR-520a-5p	CLIP-seq
MIRT1111756	hsa-miR-520f	CLIP-seq
MIRT1111757	hsa-miR-525-5p	CLIP-seq
MIRT1111758	hsa-miR-548aa	CLIP-seq
MIRT1111759	hsa-miR-569	CLIP-seq
MIRT1111760	hsa-miR-586	CLIP-seq
MIRT1111761	hsa-miR-633	CLIP-seq
MIRT1111762	hsa-miR-759	CLIP-seq
MIRT1111763	hsa-miR-889	CLIP-seq
MIRT1111764	hsa-miR-101	CLIP-seq
MIRT1111765	hsa-miR-128	CLIP-seq
MIRT1111766	hsa-miR-1301	CLIP-seq
MIRT1111767	hsa-miR-1304	CLIP-seq
MIRT1111768	hsa-miR-140-5p	CLIP-seq
MIRT1111769	hsa-miR-1470	CLIP-seq
MIRT1111736	hsa-miR-154	CLIP-seq
MIRT1111737	hsa-miR-2053	CLIP-seq
MIRT1111770	hsa-miR-23a	CLIP-seq
MIRT1111771	hsa-miR-23b	CLIP-seq
MIRT1111772	hsa-miR-299-5p	CLIP-seq
MIRT1111773	hsa-miR-3065-5p	CLIP-seq
MIRT1111774	hsa-miR-3127-3p	CLIP-seq
MIRT1111739	hsa-miR-3140-3p	CLIP-seq
MIRT1111775	hsa-miR-3671	CLIP-seq
MIRT1111742	hsa-miR-3675-5p	CLIP-seq
MIRT1111743	hsa-miR-3679-3p	CLIP-seq
MIRT1111776	hsa-miR-3914	CLIP-seq
MIRT1111744	hsa-miR-3925-5p	CLIP-seq
MIRT1111777	hsa-miR-3928	CLIP-seq
MIRT1111745	hsa-miR-3976	CLIP-seq
MIRT1111778	hsa-miR-4276	CLIP-seq
MIRT1111779	hsa-miR-4302	CLIP-seq
MIRT1111746	hsa-miR-4446-5p	CLIP-seq
MIRT1111747	hsa-miR-4469	CLIP-seq
MIRT1111780	hsa-miR-4477a	CLIP-seq
MIRT1111748	hsa-miR-4503	CLIP-seq
MIRT1111781	hsa-miR-4511	CLIP-seq
MIRT1111749	hsa-miR-4666-5p	CLIP-seq
MIRT1111782	hsa-miR-4667-3p	CLIP-seq
MIRT1111783	hsa-miR-4672	CLIP-seq
MIRT1111784	hsa-miR-4699-3p	CLIP-seq
MIRT1111750	hsa-miR-4704-5p	CLIP-seq
MIRT1111785	hsa-miR-4760-3p	CLIP-seq
MIRT1111752	hsa-miR-4777-5p	CLIP-seq
MIRT1111753	hsa-miR-4802-3p	CLIP-seq
MIRT1111754	hsa-miR-486-3p	CLIP-seq
MIRT1111755	hsa-miR-520a-5p	CLIP-seq
MIRT1111756	hsa-miR-520f	CLIP-seq
MIRT1111786	hsa-miR-520g	CLIP-seq
MIRT1111787	hsa-miR-520h	CLIP-seq
MIRT1111757	hsa-miR-525-5p	CLIP-seq
MIRT1111788	hsa-miR-548b-3p	CLIP-seq
MIRT1111759	hsa-miR-569	CLIP-seq
MIRT1111760	hsa-miR-586	CLIP-seq
MIRT1111789	hsa-miR-607	CLIP-seq
MIRT1111761	hsa-miR-633	CLIP-seq
MIRT1111790	hsa-miR-642a	CLIP-seq
MIRT1111762	hsa-miR-759	CLIP-seq
MIRT1111763	hsa-miR-889	CLIP-seq
MIRT1111764	hsa-miR-101	CLIP-seq
MIRT1111767	hsa-miR-1304	CLIP-seq
MIRT1111737	hsa-miR-2053	CLIP-seq
MIRT1111770	hsa-miR-23a	CLIP-seq
MIRT1111771	hsa-miR-23b	CLIP-seq
MIRT1111773	hsa-miR-3065-5p	CLIP-seq
MIRT1111774	hsa-miR-3127-3p	CLIP-seq
MIRT1111776	hsa-miR-3914	CLIP-seq
MIRT1111777	hsa-miR-3928	CLIP-seq
MIRT1111778	hsa-miR-4276	CLIP-seq
MIRT1111779	hsa-miR-4302	CLIP-seq
MIRT1111747	hsa-miR-4469	CLIP-seq
MIRT1111748	hsa-miR-4503	CLIP-seq
MIRT1111749	hsa-miR-4666-5p	CLIP-seq
MIRT1111783	hsa-miR-4672	CLIP-seq
MIRT1111750	hsa-miR-4704-5p	CLIP-seq
MIRT1111785	hsa-miR-4760-3p	CLIP-seq
MIRT1111753	hsa-miR-4802-3p	CLIP-seq
MIRT1111755	hsa-miR-520a-5p	CLIP-seq
MIRT1111756	hsa-miR-520f	CLIP-seq
MIRT1111786	hsa-miR-520g	CLIP-seq
MIRT1111787	hsa-miR-520h	CLIP-seq
MIRT1111757	hsa-miR-525-5p	CLIP-seq
MIRT1111759	hsa-miR-569	CLIP-seq
MIRT1111762	hsa-miR-759	CLIP-seq
MIRT1111764	hsa-miR-101	CLIP-seq
MIRT1111766	hsa-miR-1301	CLIP-seq
MIRT1111767	hsa-miR-1304	CLIP-seq
MIRT1111769	hsa-miR-1470	CLIP-seq
MIRT1111736	hsa-miR-154	CLIP-seq
MIRT1111737	hsa-miR-2053	CLIP-seq
MIRT1111770	hsa-miR-23a	CLIP-seq
MIRT1111771	hsa-miR-23b	CLIP-seq
MIRT1111773	hsa-miR-3065-5p	CLIP-seq
MIRT1111774	hsa-miR-3127-3p	CLIP-seq
MIRT2261976	hsa-miR-3130-3p	CLIP-seq
MIRT1111739	hsa-miR-3140-3p	CLIP-seq
MIRT2261977	hsa-miR-3194-3p	CLIP-seq
MIRT2261978	hsa-miR-361-3p	CLIP-seq
MIRT1111743	hsa-miR-3679-3p	CLIP-seq
MIRT1111776	hsa-miR-3914	CLIP-seq
MIRT1111777	hsa-miR-3928	CLIP-seq
MIRT1111778	hsa-miR-4276	CLIP-seq
MIRT1111779	hsa-miR-4302	CLIP-seq
MIRT1111746	hsa-miR-4446-5p	CLIP-seq
MIRT1111747	hsa-miR-4469	CLIP-seq
MIRT1111780	hsa-miR-4477a	CLIP-seq
MIRT1111748	hsa-miR-4503	CLIP-seq
MIRT1111749	hsa-miR-4666-5p	CLIP-seq
MIRT1111782	hsa-miR-4667-3p	CLIP-seq
MIRT1111783	hsa-miR-4672	CLIP-seq
MIRT1111750	hsa-miR-4704-5p	CLIP-seq
MIRT1111785	hsa-miR-4760-3p	CLIP-seq
MIRT2261979	hsa-miR-4793-3p	CLIP-seq
MIRT1111753	hsa-miR-4802-3p	CLIP-seq
MIRT1111755	hsa-miR-520a-5p	CLIP-seq
MIRT1111756	hsa-miR-520f	CLIP-seq
MIRT1111786	hsa-miR-520g	CLIP-seq
MIRT1111787	hsa-miR-520h	CLIP-seq
MIRT1111757	hsa-miR-525-5p	CLIP-seq
MIRT2261980	hsa-miR-552	CLIP-seq
MIRT1111759	hsa-miR-569	CLIP-seq
MIRT1111761	hsa-miR-633	CLIP-seq
MIRT1111762	hsa-miR-759	CLIP-seq
MIRT2261981	hsa-miR-760	CLIP-seq
MIRT1111763	hsa-miR-889	CLIP-seq
MIRT1111785	hsa-miR-4760-3p	CLIP-seq
MIRT1111764	hsa-miR-101	CLIP-seq
MIRT1111766	hsa-miR-1301	CLIP-seq
MIRT1111767	hsa-miR-1304	CLIP-seq
MIRT1111774	hsa-miR-3127-3p	CLIP-seq
MIRT1111777	hsa-miR-3928	CLIP-seq
MIRT1111778	hsa-miR-4276	CLIP-seq
MIRT1111779	hsa-miR-4302	CLIP-seq
MIRT1111780	hsa-miR-4477a	CLIP-seq
MIRT1111783	hsa-miR-4672	CLIP-seq

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005198	Function	Structural molecule activity	TAS	7557986
GO:0005515	Function	Protein binding	IPI	21346760, 21988832, 25158218, 26496610, 26524528, 29568061, 29997244, 30021884, 31467278, 32296183, 32814053
GO:0005634	Component	Nucleus	IDA	10791971
GO:0005635	Component	Nuclear envelope	IDA	21610090
GO:0005635	Component	Nuclear envelope	TAS
GO:0005637	Component	Nuclear inner membrane	IEA
GO:0005638	Component	Lamin filament	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016363	Component	Nuclear matrix	IEA
GO:0031965	Component	Nuclear membrane	HDA	16791210
GO:0031965	Component	Nuclear membrane	IDA
GO:0035722	Process	Interleukin-12-mediated signaling pathway	TAS
GO:0043274	Function	Phospholipase binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

MIM	HGNC	e!Ensembl
150340	6637	ENSG00000113368

Protein

UniProt ID

P20700

Protein name

Lamin-B1

Protein function

Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed:28716252, PubMe

PDB

2KPW , 3JT0 , 3TYY , 3UMN , 5BNW , 5VVX , 7DTG

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00038	Filament	31 → 387	Intermediate filament protein	Coiled-coil
PF00932	LTD	435 → 545	Lamin Tail Domain	Domain

Sequence

MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSAL
QLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLN
YAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAA
KKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEY
KLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRI
ESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDY
EQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVD
VEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSV
SYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVA
QRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM

Sequence length

586

Interactions

View interactions

	KEGG		Reactome
	Apoptosis Cytoskeleton in muscle cells		Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

Show/Hide Causal Diseases (9)

Disease term	Disease name	dbSNP ID	References
Causal
Cockayne syndrome	Cockayne-Pelizaeus-Merzbacher Disease	rs121917900, rs121917901, rs121917902, rs387906262, rs2132552521, rs121917903, rs1590474873, rs121917904, rs121434323, rs121434324, rs121434325, rs121434326, rs121913028, rs185142838, rs527236039 View all (69 more)
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291 View all (32 more)
Dysautonomia	Autonomic bladder dysfunction	rs111033171, rs137853022, rs28939712, rs754348901, rs749052963, rs1057517169, rs1057516865, rs763445509, rs767527819, rs781333644, rs1239081703, rs1554696574, rs539544212, rs1201626345, rs774890086 View all (27 more)
Hypomyelinating leukodystrophy	Pelizaeus-Merzbacher Disease, Atypical, Pelizaeus-Merzbacher Disease, Transitional	rs74315311, rs74315312, rs796065027, rs74315313, rs74315314, rs796065028, rs796065029, rs132630292, rs72466451, rs387906865, rs587776888, rs191582628, rs141156009, rs587776983, rs483352809 View all (91 more)
Leukodystrophy	Leukodystrophy, Adult onset autosomal dominant leukodystrophy, Adult-onset autosomal dominant leukodystrophy	rs74315475, rs72466451, rs267608671, rs181087667, rs267608682, rs267608674, rs587778271, rs148932047, rs886037931, rs368905417, rs768180196, rs1558211070, rs1558209947, rs1558210191, rs1280845604 View all (6 more)	23649844
Lung adenocarcinoma	Adenocarcinoma of lung (disorder)	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370 View all (5 more)	27602772
Mental retardation	Mild Mental Retardation	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315 View all (1024 more)
Nystagmus	Nystagmus	rs137852207, rs137852208, rs1928435502, rs137852209, rs137852210, rs1929191668, rs137852211, rs137852212, rs2124209414, rs387906720, rs387906721, rs1602791884, rs786205896
Pelizaeus-merzbacher disease	Pelizaeus-Merzbacher Disease, Adult Pelizaeus-Merzbacher Disease, Classic Pelizaeus-Merzbacher Disease	rs132630278, rs132630279, rs11543022, rs132630280, rs132630281, rs132630282, rs132630284, rs132630285, rs132630286, rs132630288, rs132630289, rs132630291, rs132630292, rs132630293, rs1569428537 View all (23 more)

Show/Hide Unknown Diseases (4)

Disease term	Disease name	References	Source
Unknown
Demyelinating leukodystrophy	Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant	21909802, 24357685, 21225301, 23649844	ClinVar
Mental depression	Depressive disorder		ClinVar
Microcephaly	microcephaly 26, primary, autosomal dominant, autosomal dominant primary microcephaly		GenCC
Dyslexia	Dyslexia		GWAS

Show/Hide Text Mining Associations (69)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma of Lung	Associate	32149105
Adenomatous Polyposis Coli	Associate	19845967
Agenesis of Corpus Callosum	Associate	32910914
Ameloblastoma	Associate	25991665
Ataxia	Associate	26053668
Ataxia Telangiectasia	Stimulate	22246186
Autosomal Recessive Primary Microcephaly	Associate	32910914, 33033404
Breast Neoplasms	Associate	24293108, 32705365, 33948615, 34237080
Breast Neoplasms	Stimulate	34459389
Carcinoma Hepatocellular	Stimulate	30897324, 34810266, 35436411
Carcinoma Hepatocellular	Associate	34511484, 36405011
Central Nervous System Diseases	Associate	23873483
Central Nervous System Vascular Malformations	Associate	23733478
Cirrhosis Cryptogenic	Associate	30878663
Colonic Diseases	Inhibit	10517909
Colorectal Neoplasms	Inhibit	10517909, 29115590
Colorectal Neoplasms	Associate	20846378, 24732130, 39390002
Demyelinating Diseases	Associate	23873483, 35247231
Down Syndrome	Associate	37451904
Drug Related Side Effects and Adverse Reactions	Associate	24990611
Dystonia	Associate	34438319
Endometriosis	Associate	35269619, 36277723, 39411815
Esophageal Neoplasms	Associate	34511484
Gastrointestinal Neoplasms	Associate	10517909
Genetic Diseases Inborn	Associate	23873483
Glioma	Associate	33956061
Growth Disorders	Associate	32910914
Heredodegenerative Disorders Nervous System	Associate	26053668, 35247231
Intellectual Disability	Associate	32910914
Laminopathies	Associate	29753763, 33033404, 36461070
Leukemia	Associate	24990611
Leukemia Myeloid Acute	Associate	32161403, 35395184
Leukemia Prolymphocytic T Cell	Associate	28804121
Leukodystrophy Metachromatic	Associate	23261988, 23439683, 23649844, 23873483, 26053668, 30192380, 32910914, 33034697
Lung Neoplasms	Associate	10517909
Lupus Erythematosus Systemic	Associate	12384929
Lymphoma	Associate	28804121
Lymphoma B Cell	Associate	28804121
Lymphoma Follicular	Associate	28804121
Lymphoma Non Hodgkin	Associate	36945359
Melanoma	Associate	35883595
Microcephaly	Associate	32910914
Microcephaly autosomal dominant	Associate	32910914
Mitochondrial Diseases	Associate	30692212
Mouth Diseases	Associate	35269619
Muscular Dystrophy Congenital Megaconial Type	Associate	37448194
Myelodysplastic Syndromes	Associate	35395184
Neoplasm Metastasis	Associate	34459389, 35436411, 39390002
Neoplasms	Associate	23934658, 32987785, 34511484, 34639214, 34810266, 35395184, 35436411, 36461070
Neoplasms	Inhibit	27449096
Neural Tube Defects	Associate	23733478
Neuroaxonal Dystrophies	Associate	35247231
Oncogene Addiction	Associate	22246186
Osteoarthritis	Associate	25797039
Pelger Huet Anomaly	Associate	35395184
Progeria	Associate	23439683
Progeria	Inhibit	23873483
Progeroid syndrome neonatal	Associate	37451904
Prostatic Neoplasms	Associate	31306099, 34511484
Pulmonary Disease Chronic Obstructive	Inhibit	30692212
Sarcoma	Stimulate	35356902
Sarcoma Ewing	Associate	39367409
Spastic Paraplegia Hereditary	Associate	26053668
Spinal Cord Diseases	Associate	26053668
Stomach Neoplasms	Inhibit	10517909
Stomach Neoplasms	Associate	27449096
Thrombosis	Associate	12384929
Urinary Bladder Neoplasms	Associate	35685866
Uterine Cervical Neoplasms	Associate	34511484

LMNB1 (lamin B1)