LIPC (lipase C, hepatic type)

Gene

• Entrez ID: 3990
• Gene name: Lipase C, hepatic type
• Gene symbol: LIPC
• Synonyms (NCBI Gene): HDLCQ12, HL, HTGL, LIPH
• Chromosome: 15
• Chromosome location: 15q21.3
• Summary: LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs2070895	G>A,T	Risk-factor, association	5 prime UTR variant, genic upstream transcript variant, intron variant, upstream transcript variant
rs113298164	C>T	Pathogenic-likely-pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs1566946168	G>A	Pathogenic	Coding sequence variant, missense variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019266	hsa-miR-148b-3p	Microarray	17612493
MIRT023497	hsa-miR-1-3p	Microarray	18668037
MIRT714619	hsa-miR-5692a	HITS-CLIP	19536157
MIRT714618	hsa-miR-5000-5p	HITS-CLIP	19536157
MIRT714617	hsa-miR-4704-3p	HITS-CLIP	19536157
MIRT714616	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT667610	hsa-miR-512-5p	HITS-CLIP	23824327
MIRT667609	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT667607	hsa-miR-4695-5p	HITS-CLIP	23824327
MIRT667608	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667606	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667605	hsa-miR-940	HITS-CLIP	23824327
MIRT667604	hsa-miR-3929	HITS-CLIP	23824327
MIRT667603	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667602	hsa-miR-4478	HITS-CLIP	23824327
MIRT667601	hsa-miR-5690	HITS-CLIP	23824327
MIRT667600	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667599	hsa-miR-4459	HITS-CLIP	23824327
MIRT667598	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT667597	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT474120	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT474118	hsa-miR-1827	HITS-CLIP	23824327
MIRT667596	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667595	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT672335	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT667594	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT672334	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT672333	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT667593	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT672332	hsa-miR-4455	HITS-CLIP	23824327
MIRT672331	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT667592	hsa-miR-7977	HITS-CLIP	23824327
MIRT672330	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT667591	hsa-miR-665	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT667611	hsa-miR-874-5p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT667610	hsa-miR-512-5p	HITS-CLIP	23824327
MIRT667609	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT667607	hsa-miR-4695-5p	HITS-CLIP	23824327
MIRT667608	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667606	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667605	hsa-miR-940	HITS-CLIP	23824327
MIRT667604	hsa-miR-3929	HITS-CLIP	23824327
MIRT667603	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667602	hsa-miR-4478	HITS-CLIP	23824327
MIRT667601	hsa-miR-5690	HITS-CLIP	23824327
MIRT667600	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667599	hsa-miR-4459	HITS-CLIP	23824327
MIRT667598	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT667597	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT474120	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT474118	hsa-miR-1827	HITS-CLIP	23824327
MIRT667596	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667595	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT667594	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT667593	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT667592	hsa-miR-7977	HITS-CLIP	23824327
MIRT667591	hsa-miR-665	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT474126	hsa-miR-302f	PAR-CLIP	23592263
MIRT474125	hsa-miR-3123	PAR-CLIP	23592263
MIRT474124	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT474123	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT474121	hsa-miR-3919	PAR-CLIP	23592263
MIRT474122	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT474120	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT474119	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT474118	hsa-miR-1827	PAR-CLIP	23592263
MIRT474117	hsa-miR-3612	PAR-CLIP	23592263
MIRT474116	hsa-miR-650	PAR-CLIP	23592263
MIRT448688	hsa-miR-1273e	PAR-CLIP	23592263
MIRT448697	hsa-miR-211-5p	PAR-CLIP	22100165
MIRT448696	hsa-miR-204-5p	PAR-CLIP	22100165
MIRT448695	hsa-miR-4780	PAR-CLIP	22100165
MIRT448694	hsa-miR-6780b-3p	PAR-CLIP	22100165
MIRT448693	hsa-miR-6734-3p	PAR-CLIP	22100165
MIRT448691	hsa-miR-4635	PAR-CLIP	22100165
MIRT448692	hsa-miR-4699-5p	PAR-CLIP	22100165
MIRT448690	hsa-miR-623	PAR-CLIP	22100165
MIRT448689	hsa-miR-4709-3p	PAR-CLIP	22100165
MIRT448688	hsa-miR-1273e	PAR-CLIP	22100165
MIRT448687	hsa-miR-4755-5p	PAR-CLIP	22100165
MIRT448686	hsa-miR-5006-3p	PAR-CLIP	22100165
MIRT448697	hsa-miR-211-5p	PAR-CLIP	22100165
MIRT448696	hsa-miR-204-5p	PAR-CLIP	22100165
MIRT448695	hsa-miR-4780	PAR-CLIP	22100165
MIRT448694	hsa-miR-6780b-3p	PAR-CLIP	22100165
MIRT448693	hsa-miR-6734-3p	PAR-CLIP	22100165
MIRT448691	hsa-miR-4635	PAR-CLIP	22100165
MIRT448692	hsa-miR-4699-5p	PAR-CLIP	22100165
MIRT448690	hsa-miR-623	PAR-CLIP	22100165
MIRT448689	hsa-miR-4709-3p	PAR-CLIP	22100165
MIRT448688	hsa-miR-1273e	PAR-CLIP	22100165
MIRT448687	hsa-miR-4755-5p	PAR-CLIP	22100165
MIRT448686	hsa-miR-5006-3p	PAR-CLIP	22100165
MIRT714619	hsa-miR-5692a	HITS-CLIP	19536157
MIRT714618	hsa-miR-5000-5p	HITS-CLIP	19536157
MIRT714617	hsa-miR-4704-3p	HITS-CLIP	19536157
MIRT714616	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT667610	hsa-miR-512-5p	HITS-CLIP	23824327
MIRT667609	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT667607	hsa-miR-4695-5p	HITS-CLIP	23824327
MIRT667608	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667606	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667605	hsa-miR-940	HITS-CLIP	23824327
MIRT667604	hsa-miR-3929	HITS-CLIP	23824327
MIRT667603	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667602	hsa-miR-4478	HITS-CLIP	23824327
MIRT667601	hsa-miR-5690	HITS-CLIP	23824327
MIRT667600	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667599	hsa-miR-4459	HITS-CLIP	23824327
MIRT667598	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT667597	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT474120	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT474118	hsa-miR-1827	HITS-CLIP	23824327
MIRT667596	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667595	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT672335	hsa-miR-5589-3p	HITS-CLIP	23824327
MIRT667594	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT672334	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT672333	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT667593	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT672332	hsa-miR-4455	HITS-CLIP	23824327
MIRT672331	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT667592	hsa-miR-7977	HITS-CLIP	23824327
MIRT672330	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT667591	hsa-miR-665	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT667611	hsa-miR-874-5p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT667610	hsa-miR-512-5p	HITS-CLIP	23824327
MIRT667609	hsa-miR-510-5p	HITS-CLIP	23824327
MIRT667607	hsa-miR-4695-5p	HITS-CLIP	23824327
MIRT667608	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT667606	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT667605	hsa-miR-940	HITS-CLIP	23824327
MIRT667604	hsa-miR-3929	HITS-CLIP	23824327
MIRT667603	hsa-miR-4419b	HITS-CLIP	23824327
MIRT667602	hsa-miR-4478	HITS-CLIP	23824327
MIRT667601	hsa-miR-5690	HITS-CLIP	23824327
MIRT667600	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT667599	hsa-miR-4459	HITS-CLIP	23824327
MIRT667598	hsa-miR-4433a-3p	HITS-CLIP	23824327
MIRT667597	hsa-miR-3664-3p	HITS-CLIP	23824327
MIRT474120	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT474118	hsa-miR-1827	HITS-CLIP	23824327
MIRT667596	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT667595	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT667594	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT667593	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT667592	hsa-miR-7977	HITS-CLIP	23824327
MIRT667591	hsa-miR-665	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT611658	hsa-miR-7113-5p	HITS-CLIP	23824327
MIRT611657	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT611656	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT611655	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT611654	hsa-miR-1248	HITS-CLIP	23824327
MIRT611653	hsa-miR-4287	HITS-CLIP	23824327
MIRT611652	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT611651	hsa-miR-3190-5p	HITS-CLIP	23824327
MIRT611650	hsa-miR-3176	HITS-CLIP	23824327
MIRT611649	hsa-miR-3922-3p	HITS-CLIP	23824327
MIRT611648	hsa-miR-219a-5p	HITS-CLIP	23824327
MIRT611647	hsa-miR-4782-3p	HITS-CLIP	23824327
MIRT611646	hsa-miR-6766-3p	HITS-CLIP	23824327
MIRT611645	hsa-miR-3909	HITS-CLIP	23824327
MIRT611644	hsa-miR-6852-3p	HITS-CLIP	23824327
MIRT611643	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT611642	hsa-miR-676-3p	HITS-CLIP	23824327
MIRT611641	hsa-miR-2355-3p	HITS-CLIP	23824327
MIRT474126	hsa-miR-302f	PAR-CLIP	23592263
MIRT474125	hsa-miR-3123	PAR-CLIP	23592263
MIRT474124	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT474123	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT474121	hsa-miR-3919	PAR-CLIP	23592263
MIRT474122	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT474120	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT474119	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT474118	hsa-miR-1827	PAR-CLIP	23592263
MIRT474117	hsa-miR-3612	PAR-CLIP	23592263
MIRT474116	hsa-miR-650	PAR-CLIP	23592263
MIRT448688	hsa-miR-1273e	PAR-CLIP	23592263
MIRT448697	hsa-miR-211-5p	PAR-CLIP	22100165
MIRT448696	hsa-miR-204-5p	PAR-CLIP	22100165
MIRT448695	hsa-miR-4780	PAR-CLIP	22100165
MIRT448694	hsa-miR-6780b-3p	PAR-CLIP	22100165
MIRT448693	hsa-miR-6734-3p	PAR-CLIP	22100165
MIRT448691	hsa-miR-4635	PAR-CLIP	22100165
MIRT448692	hsa-miR-4699-5p	PAR-CLIP	22100165
MIRT448690	hsa-miR-623	PAR-CLIP	22100165
MIRT448689	hsa-miR-4709-3p	PAR-CLIP	22100165
MIRT448688	hsa-miR-1273e	PAR-CLIP	22100165
MIRT448687	hsa-miR-4755-5p	PAR-CLIP	22100165
MIRT448686	hsa-miR-5006-3p	PAR-CLIP	22100165
MIRT448697	hsa-miR-211-5p	PAR-CLIP	22100165
MIRT448696	hsa-miR-204-5p	PAR-CLIP	22100165
MIRT448695	hsa-miR-4780	PAR-CLIP	22100165
MIRT448694	hsa-miR-6780b-3p	PAR-CLIP	22100165
MIRT448693	hsa-miR-6734-3p	PAR-CLIP	22100165
MIRT448691	hsa-miR-4635	PAR-CLIP	22100165
MIRT448692	hsa-miR-4699-5p	PAR-CLIP	22100165
MIRT448690	hsa-miR-623	PAR-CLIP	22100165
MIRT448689	hsa-miR-4709-3p	PAR-CLIP	22100165
MIRT448688	hsa-miR-1273e	PAR-CLIP	22100165
MIRT448687	hsa-miR-4755-5p	PAR-CLIP	22100165
MIRT448686	hsa-miR-5006-3p	PAR-CLIP	22100165

Transcription factors

Transcription factor	Regulation	Reference
HNF4A	Unknown	16603721
SREBF2	Unknown	15721010
USF1	Unknown	15721010;19416648
USF2	Unknown	19416648

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004465	Function	Lipoprotein lipase activity	IBA
GO:0004620	Function	Phospholipase activity	TAS	3244012
GO:0004622	Function	Phosphatidylcholine lysophospholipase activity	IEA
GO:0004806	Function	Triacylglycerol lipase activity	IDA	182536, 2839510, 7592706, 8798474, 12032167, 26193433
GO:0004806	Function	Triacylglycerol lipase activity	IEA
GO:0005515	Function	Protein binding	IPI	14967812
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IDA	2839510
GO:0005615	Component	Extracellular space	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	TAS
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IBA
GO:0006633	Process	Fatty acid biosynthetic process	IDA	182536
GO:0008201	Function	Heparin binding	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0008970	Function	Phospholipase A1 activity	IBA
GO:0008970	Function	Phospholipase A1 activity	IDA	7592706, 12032167, 26193433
GO:0008970	Function	Phospholipase A1 activity	IEA
GO:0016042	Process	Lipid catabolic process	IEA
GO:0016298	Function	Lipase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019433	Process	Triglyceride catabolic process	IBA
GO:0019433	Process	Triglyceride catabolic process	IDA	182536, 2839510, 8640403
GO:0030169	Function	Low-density lipoprotein particle binding	ISS
GO:0030301	Process	Cholesterol transport	IEA
GO:0034185	Function	Apolipoprotein binding	IBA
GO:0034185	Function	Apolipoprotein binding	ISS
GO:0034364	Component	High-density lipoprotein particle	IEA
GO:0034372	Process	Very-low-density lipoprotein particle remodeling	IDA	8640403
GO:0034373	Process	Intermediate-density lipoprotein particle remodeling	TAS	2839510
GO:0034374	Process	Low-density lipoprotein particle remodeling	IMP	3244012
GO:0034375	Process	High-density lipoprotein particle remodeling	IBA
GO:0034375	Process	High-density lipoprotein particle remodeling	IMP	3244012
GO:0034382	Process	Chylomicron remnant clearance	TAS	9685400
GO:0034638	Process	Phosphatidylcholine catabolic process	TAS	2839510
GO:0042632	Process	Cholesterol homeostasis	IBA
GO:0042632	Process	Cholesterol homeostasis	IEA
GO:0042632	Process	Cholesterol homeostasis	IMP	1883393
GO:0043691	Process	Reverse cholesterol transport	IC	14531818
GO:0052689	Function	Carboxylic ester hydrolase activity	IEA
GO:0070328	Process	Triglyceride homeostasis	IMP	1883393

Other IDs

• MIM: 151670
• HGNC: 6619
• e!Ensembl: ENSG00000166035

Protein

• UniProt ID: P11150
• Protein name: Hepatic triacylglycerol lipase (HL) (Hepatic lipase) (EC 3.1.1.3) (Lipase member C) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A1) (EC 3.1.1.32)
• Protein function: Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00151	Lipase	15 → 349	Lipase	Domain
  PF01477	PLAT	354 → 485	PLAT/LH2 domain	Domain

• Sequence:

  MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQ
  GCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLV
  DWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSS
  IGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGH
  YDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAY
  PCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQF
  INQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKW
  ENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQ
  EKIFVKCEIKSKTSKRKIR

• Sequence length: 499

Pathways

KEGG:

Glycerolipid metabolism
Metabolic pathways
Cholesterol metabolism

Reactome:

Assembly of active LPL and LIPC lipase complexes
Chylomicron clearance

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Abnormal circulating lipid concentration	Likely pathogenic; Pathogenic	rs2548785784, rs1277669986	RCV002283591 RCV002283592
Cervical cancer	Pathogenic	rs1277669986	RCV005930265
Hyperlipidemia due to hepatic triglyceride lipase deficiency	Pathogenic	rs1566946168	RCV000022642

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
-	no classification for the single variant	rs12594375, rs8023503	-
Cholangiocarcinoma	Benign	rs6080	RCV005893403
Diabetes mellitus type 2, susceptibility to	Benign	rs2070895	RCV000015539
Gastric cancer	Benign	rs6080	RCV005893400
Hepatocellular carcinoma	Benign	rs4774305	RCV005917390
High density lipoprotein cholesterol level quantitative trait locus 12	Conflicting classifications of pathogenicity; Uncertain significance; association; Benign; Likely benign	rs184587533, rs575306493, rs767952446, rs752423767, rs145811475, rs768409840, rs1893340418, rs372553692, rs137926228, rs113298164, rs1800588, rs2070895, rs140272400	RCV003228002 RCV003336506 RCV002468875 RCV006261789 RCV003228622 RCV003228642 RCV003228653 RCV003228659 RCV003336603 RCV003227602 RCV000015538 RCV000015540 RCV002504083
HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 6	Uncertain significance	rs2140922013	RCV001837070
LIPC-related disorder	Uncertain significance; Likely benign; Conflicting classifications of pathogenicity; Benign	rs1893623220, rs939351730, rs776858148, rs140272400, rs768982423, rs113174258, rs142036980	RCV004759003 RCV003959247 RCV003930365 RCV003972349 RCV003957637 RCV003935976 RCV003950731
Ovarian serous cystadenocarcinoma	Benign	rs6080	RCV005893401
Sarcoma	Benign	rs6080	RCV005893399
Thymoma	Benign	rs6080	RCV005893402
Type 1 diabetes mellitus 2	Conflicting classifications of pathogenicity	rs113298164	RCV003227602
Type 2 diabetes mellitus	Conflicting classifications of pathogenicity; Uncertain significance; Benign; Likely benign	rs184587533, rs369262181, rs575306493, rs752423767, rs145811475, rs768409840, rs1893340418, rs372553692, rs2548782220, rs137926228, rs113298164, rs371573112, rs140272400, rs749932377, rs142036980	RCV003228002 RCV003401945 RCV003336506 RCV006261789 RCV003228622 RCV003228642 RCV003228653 RCV003228659 RCV003228688 RCV003336603 RCV002247345 RCV005396955 RCV002504083 RCV005392375 RCV003227876
Uterine corpus endometrial carcinoma	Benign; Likely benign	rs58453124	RCV005893404

Associations from Text Mining
Disease Name	Relationship Type	References
3 Hydroxy 3 Methylglutaryl CoA Lyase Deficiency	Inhibit	17173698
3 Hydroxy 3 Methylglutaryl CoA Lyase Deficiency	Associate	22955918, 9392428, 9463337
Abortion Spontaneous	Associate	29270100
Altitude Sickness	Associate	29625625
Alzheimer Disease	Associate	23181436
Arthropathy progressive pseudorheumatoid of childhood	Associate	10681408
Atherosclerosis	Associate	10681408, 12354428, 15656877, 15961789, 16164573, 23181436, 23991054
Brain Ischemia	Associate	12354428
Carcinogenesis	Associate	22294764
Carcinoma Hepatocellular	Stimulate	2542313
Carcinoma Hepatocellular	Associate	30600300, 36274132
Carcinoma Non Small Cell Lung	Associate	23343765
Cardiomyopathy Restrictive	Associate	12621166
Cardiovascular Diseases	Associate	19691831, 31077211
Carotid Stenosis	Associate	12354428
Colorectal Neoplasms	Associate	22294764
Conversion Disorder	Associate	35388043
Corneal Neovascularization	Associate	22247473
Coronary Artery Disease	Associate	10681408, 12364543, 12417924, 12883629, 12964943, 17175070, 21548985, 23874450, 24504152, 29310573, 33004870
Coronary Disease	Associate	10946018, 20855565, 21960661, 30371334
Death	Associate	29270100
Diabetes Mellitus Type 2	Associate	12547874, 15656877, 22073289
Diabetic Nephropathies	Associate	23879411
Dyslipidemias	Associate	16343038, 25117371, 28315561, 39518997
Encephalitis Japanese	Associate	14657196
Glucose Intolerance	Associate	15656877
Glycogen Storage Disease Type II	Associate	32979492
Guillain Barre Syndrome	Associate	35388043
Hearing Loss	Associate	34230634, 34758154
Hearing Loss Sensorineural	Associate	27583405
Heart Diseases	Associate	16164573
Hemochromatosis	Associate	29270100
Hemorrhagic Fever American	Associate	14657196
Hereditary leiomyomatosis and renal cell cancer	Associate	22955918
HIV Infections	Associate	12837664
Hypercholesterolemia	Associate	19695855
Hyperlipidemia Familial Combined	Associate	10681408
Hyperlipidemias	Associate	23991054
Hyperlipoproteinemia Type I	Associate	8301230
Hyperlipoproteinemia Type II	Associate	24504152, 36648309
Hypertension	Associate	25117371, 25587205
Hypertension Pregnancy Induced	Associate	25117371
Hypothyroidism	Inhibit	8354961
Hypoxia	Associate	29625625
Inflammation	Associate	11988625, 12354428, 37461045
Insulin Resistance	Associate	10428983
Long QT Syndrome	Associate	29270100
Macular Degeneration	Associate	20385826, 20888482, 21139980, 21447678, 21906714, 22694956, 23348725, 24608419, 26854823, 27099955, 28456421, 32553749, 34061866, 35027571, 36055244
Macular Degeneration	Inhibit	24223199
Metabolic Syndrome	Associate	19695855, 34503513, 34801968
Metabolism Inborn Errors	Associate	8808756
Myocardial Infarction	Associate	19695855
Myocardial Ischemia	Associate	12798568
Neoplasms Adipose Tissue	Associate	31077211
Neurodegenerative Diseases	Associate	23181436
Obesity	Associate	14657196, 15941898, 23039238, 23109900, 25926410
Overweight	Associate	16316842, 23039238, 23109900, 25926410
Pancreatitis	Associate	8301230
Peripheral Arterial Disease	Associate	16164573
Polypoidal Choroidal Vasculopathy	Associate	26624898, 31877157
Pre Eclampsia	Associate	16316842, 25117371
Pregnancy Complications	Associate	25117371
Pregnancy in Diabetics	Associate	25117371
Pressure Ulcer	Associate	22606049
Proteinuria	Associate	31286991
Proteinuria	Stimulate	32280690
Reticular dysgenesis	Associate	32163116
Retinal Drusen	Inhibit	21447678
Retinal Drusen	Associate	22247473
Stroke	Associate	18622260
Vascular Diseases	Associate	14531818
Weight Loss	Associate	25926410