Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3984
Gene name Gene Name - the full gene name approved by the HGNC.	LIM domain kinase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LIMK1
Synonyms (NCBI Gene) Gene synonyms aliases	LIMK, LIMK-1
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q11.23
Summary Summary of gene provided in NCBI Entrez Gene.	There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the

Show/Hide all(247)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020461	hsa-miR-106b-5p	Microarray	17242205
MIRT042722	hsa-miR-346	CLASH	23622248
MIRT052914	hsa-miR-20a-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	24858712
MIRT054222	hsa-miR-17-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	23029228
MIRT054223	hsa-miR-20b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	23029228
MIRT054224	hsa-miR-106a-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	23029228
MIRT438605	hsa-miR-143-3p	Luciferase reporter assay, Western blot	25003638
MIRT438605	hsa-miR-143-3p	Luciferase reporter assay, Western blot	25003638
MIRT054224	hsa-miR-106a-5p	PAR-CLIP	27292025
MIRT020461	hsa-miR-106b-5p	PAR-CLIP	27292025
MIRT054222	hsa-miR-17-5p	PAR-CLIP	27292025
MIRT052914	hsa-miR-20a-5p	PAR-CLIP	27292025
MIRT054223	hsa-miR-20b-5p	PAR-CLIP	27292025
MIRT755422	hsa-miR-27a-3p	Western blotting, qRT-PCR	37884644
MIRT1109645	hsa-miR-106a	CLIP-seq
MIRT1109646	hsa-miR-106b	CLIP-seq
MIRT1109647	hsa-miR-1193	CLIP-seq
MIRT1109648	hsa-miR-1207-3p	CLIP-seq
MIRT1109649	hsa-miR-1224-3p	CLIP-seq
MIRT1109650	hsa-miR-1229	CLIP-seq
MIRT1109651	hsa-miR-1260	CLIP-seq
MIRT1109652	hsa-miR-1260b	CLIP-seq
MIRT1109653	hsa-miR-1263	CLIP-seq
MIRT1109654	hsa-miR-128	CLIP-seq
MIRT1109655	hsa-miR-1280	CLIP-seq
MIRT1109656	hsa-miR-1285	CLIP-seq
MIRT1109657	hsa-miR-1293	CLIP-seq
MIRT1109658	hsa-miR-1301	CLIP-seq
MIRT1109659	hsa-miR-1343	CLIP-seq
MIRT1109660	hsa-miR-149	CLIP-seq
MIRT1109661	hsa-miR-17	CLIP-seq
MIRT1109662	hsa-miR-1827	CLIP-seq
MIRT1109663	hsa-miR-1909	CLIP-seq
MIRT1109664	hsa-miR-200b	CLIP-seq
MIRT1109665	hsa-miR-200c	CLIP-seq
MIRT1109666	hsa-miR-20a	CLIP-seq
MIRT1109667	hsa-miR-20b	CLIP-seq
MIRT1109668	hsa-miR-224	CLIP-seq
MIRT1109669	hsa-miR-27a	CLIP-seq
MIRT1109670	hsa-miR-27b	CLIP-seq
MIRT1109671	hsa-miR-3119	CLIP-seq
MIRT1109672	hsa-miR-3147	CLIP-seq
MIRT1109673	hsa-miR-3150b-3p	CLIP-seq
MIRT1109674	hsa-miR-3187-5p	CLIP-seq
MIRT1109675	hsa-miR-3189-3p	CLIP-seq
MIRT1109676	hsa-miR-326	CLIP-seq
MIRT1109677	hsa-miR-330-5p	CLIP-seq
MIRT1109678	hsa-miR-3609	CLIP-seq
MIRT1109679	hsa-miR-3650	CLIP-seq
MIRT1109680	hsa-miR-3653	CLIP-seq
MIRT1109681	hsa-miR-3658	CLIP-seq
MIRT1109682	hsa-miR-3690	CLIP-seq
MIRT1109683	hsa-miR-374c	CLIP-seq
MIRT1109684	hsa-miR-378g	CLIP-seq
MIRT1109685	hsa-miR-384	CLIP-seq
MIRT1109686	hsa-miR-3921	CLIP-seq
MIRT1109687	hsa-miR-3944-5p	CLIP-seq
MIRT1109688	hsa-miR-4254	CLIP-seq
MIRT1109689	hsa-miR-4273	CLIP-seq
MIRT1109690	hsa-miR-4281	CLIP-seq
MIRT1109691	hsa-miR-429	CLIP-seq
MIRT1109692	hsa-miR-4328	CLIP-seq
MIRT1109693	hsa-miR-4425	CLIP-seq
MIRT1109694	hsa-miR-4445	CLIP-seq
MIRT1109695	hsa-miR-4483	CLIP-seq
MIRT1109696	hsa-miR-4486	CLIP-seq
MIRT1109697	hsa-miR-4504	CLIP-seq
MIRT1109698	hsa-miR-450b-3p	CLIP-seq
MIRT1109699	hsa-miR-4520a-5p	CLIP-seq
MIRT1109700	hsa-miR-4520b-5p	CLIP-seq
MIRT1109701	hsa-miR-4640-5p	CLIP-seq
MIRT1109702	hsa-miR-4649-3p	CLIP-seq
MIRT1109703	hsa-miR-4653-5p	CLIP-seq
MIRT1109704	hsa-miR-4660	CLIP-seq
MIRT1109705	hsa-miR-4677-5p	CLIP-seq
MIRT1109706	hsa-miR-4685-5p	CLIP-seq
MIRT1109707	hsa-miR-4689	CLIP-seq
MIRT1109708	hsa-miR-4698	CLIP-seq
MIRT1109709	hsa-miR-4726-5p	CLIP-seq
MIRT1109710	hsa-miR-4784	CLIP-seq
MIRT1109711	hsa-miR-4796-3p	CLIP-seq
MIRT1109712	hsa-miR-4804-5p	CLIP-seq
MIRT1109713	hsa-miR-502-5p	CLIP-seq
MIRT1109714	hsa-miR-5047	CLIP-seq
MIRT1109715	hsa-miR-513a-5p	CLIP-seq
MIRT1109716	hsa-miR-519a	CLIP-seq
MIRT1109717	hsa-miR-519d	CLIP-seq
MIRT1109718	hsa-miR-520g	CLIP-seq
MIRT1109719	hsa-miR-539	CLIP-seq
MIRT1109720	hsa-miR-548ah	CLIP-seq
MIRT1109721	hsa-miR-612	CLIP-seq
MIRT1109722	hsa-miR-629	CLIP-seq
MIRT1109723	hsa-miR-655	CLIP-seq
MIRT1109724	hsa-miR-659	CLIP-seq
MIRT1109725	hsa-miR-661	CLIP-seq
MIRT1109726	hsa-miR-662	CLIP-seq
MIRT1109727	hsa-miR-760	CLIP-seq
MIRT1109728	hsa-miR-769-3p	CLIP-seq
MIRT1109729	hsa-miR-93	CLIP-seq
MIRT1109645	hsa-miR-106a	CLIP-seq
MIRT1109646	hsa-miR-106b	CLIP-seq
MIRT1109647	hsa-miR-1193	CLIP-seq
MIRT1109649	hsa-miR-1224-3p	CLIP-seq
MIRT1109651	hsa-miR-1260	CLIP-seq
MIRT1109652	hsa-miR-1260b	CLIP-seq
MIRT1109655	hsa-miR-1280	CLIP-seq
MIRT1109657	hsa-miR-1293	CLIP-seq
MIRT2030530	hsa-miR-1324	CLIP-seq
MIRT1109659	hsa-miR-1343	CLIP-seq
MIRT1109661	hsa-miR-17	CLIP-seq
MIRT1109663	hsa-miR-1909	CLIP-seq
MIRT2030531	hsa-miR-1913	CLIP-seq
MIRT1109666	hsa-miR-20a	CLIP-seq
MIRT1109667	hsa-miR-20b	CLIP-seq
MIRT1109668	hsa-miR-224	CLIP-seq
MIRT2030532	hsa-miR-3136-3p	CLIP-seq
MIRT1109672	hsa-miR-3147	CLIP-seq
MIRT1109673	hsa-miR-3150b-3p	CLIP-seq
MIRT1109675	hsa-miR-3189-3p	CLIP-seq
MIRT2030533	hsa-miR-324-3p	CLIP-seq
MIRT2030534	hsa-miR-3616-3p	CLIP-seq
MIRT2030535	hsa-miR-3619-3p	CLIP-seq
MIRT1109682	hsa-miR-3690	CLIP-seq
MIRT1109686	hsa-miR-3921	CLIP-seq
MIRT1109688	hsa-miR-4254	CLIP-seq
MIRT2030536	hsa-miR-4257	CLIP-seq
MIRT2030537	hsa-miR-4270	CLIP-seq
MIRT2030538	hsa-miR-4286	CLIP-seq
MIRT2030539	hsa-miR-4300	CLIP-seq
MIRT1109693	hsa-miR-4425	CLIP-seq
MIRT2030540	hsa-miR-4441	CLIP-seq
MIRT1109694	hsa-miR-4445	CLIP-seq
MIRT1109695	hsa-miR-4483	CLIP-seq
MIRT1109698	hsa-miR-450b-3p	CLIP-seq
MIRT2030541	hsa-miR-4633-3p	CLIP-seq
MIRT1109702	hsa-miR-4649-3p	CLIP-seq
MIRT1109703	hsa-miR-4653-5p	CLIP-seq
MIRT1109706	hsa-miR-4685-5p	CLIP-seq
MIRT1109707	hsa-miR-4689	CLIP-seq
MIRT2030542	hsa-miR-4721	CLIP-seq
MIRT2030543	hsa-miR-4757-5p	CLIP-seq
MIRT2030544	hsa-miR-4776-5p	CLIP-seq
MIRT1109710	hsa-miR-4784	CLIP-seq
MIRT1109712	hsa-miR-4804-5p	CLIP-seq
MIRT1109716	hsa-miR-519a	CLIP-seq
MIRT1109717	hsa-miR-519d	CLIP-seq
MIRT1109718	hsa-miR-520g	CLIP-seq
MIRT2030545	hsa-miR-552	CLIP-seq
MIRT2030546	hsa-miR-619	CLIP-seq
MIRT1109725	hsa-miR-661	CLIP-seq
MIRT1109727	hsa-miR-760	CLIP-seq
MIRT1109728	hsa-miR-769-3p	CLIP-seq
MIRT2030547	hsa-miR-920	CLIP-seq
MIRT1109729	hsa-miR-93	CLIP-seq
MIRT1109645	hsa-miR-106a	CLIP-seq
MIRT1109646	hsa-miR-106b	CLIP-seq
MIRT1109647	hsa-miR-1193	CLIP-seq
MIRT1109649	hsa-miR-1224-3p	CLIP-seq
MIRT1109651	hsa-miR-1260	CLIP-seq
MIRT1109652	hsa-miR-1260b	CLIP-seq
MIRT1109654	hsa-miR-128	CLIP-seq
MIRT1109655	hsa-miR-1280	CLIP-seq
MIRT1109657	hsa-miR-1293	CLIP-seq
MIRT1109659	hsa-miR-1343	CLIP-seq
MIRT1109661	hsa-miR-17	CLIP-seq
MIRT1109662	hsa-miR-1827	CLIP-seq
MIRT1109664	hsa-miR-200b	CLIP-seq
MIRT1109665	hsa-miR-200c	CLIP-seq
MIRT1109666	hsa-miR-20a	CLIP-seq
MIRT1109667	hsa-miR-20b	CLIP-seq
MIRT1109668	hsa-miR-224	CLIP-seq
MIRT1109669	hsa-miR-27a	CLIP-seq
MIRT1109670	hsa-miR-27b	CLIP-seq
MIRT1109672	hsa-miR-3147	CLIP-seq
MIRT1109675	hsa-miR-3189-3p	CLIP-seq
MIRT1109682	hsa-miR-3690	CLIP-seq
MIRT1109683	hsa-miR-374c	CLIP-seq
MIRT1109685	hsa-miR-384	CLIP-seq
MIRT1109688	hsa-miR-4254	CLIP-seq
MIRT2030536	hsa-miR-4257	CLIP-seq
MIRT1109690	hsa-miR-4281	CLIP-seq
MIRT1109691	hsa-miR-429	CLIP-seq
MIRT2261286	hsa-miR-4290	CLIP-seq
MIRT1109692	hsa-miR-4328	CLIP-seq
MIRT1109693	hsa-miR-4425	CLIP-seq
MIRT1109694	hsa-miR-4445	CLIP-seq
MIRT2261287	hsa-miR-4480	CLIP-seq
MIRT1109695	hsa-miR-4483	CLIP-seq
MIRT1109698	hsa-miR-450b-3p	CLIP-seq
MIRT1109702	hsa-miR-4649-3p	CLIP-seq
MIRT1109712	hsa-miR-4804-5p	CLIP-seq
MIRT1109713	hsa-miR-502-5p	CLIP-seq
MIRT1109715	hsa-miR-513a-5p	CLIP-seq
MIRT1109716	hsa-miR-519a	CLIP-seq
MIRT1109717	hsa-miR-519d	CLIP-seq
MIRT1109718	hsa-miR-520g	CLIP-seq
MIRT1109719	hsa-miR-539	CLIP-seq
MIRT1109722	hsa-miR-629	CLIP-seq
MIRT1109723	hsa-miR-655	CLIP-seq
MIRT1109724	hsa-miR-659	CLIP-seq
MIRT1109726	hsa-miR-662	CLIP-seq
MIRT1109728	hsa-miR-769-3p	CLIP-seq
MIRT1109729	hsa-miR-93	CLIP-seq
MIRT1109648	hsa-miR-1207-3p	CLIP-seq
MIRT1109649	hsa-miR-1224-3p	CLIP-seq
MIRT1109651	hsa-miR-1260	CLIP-seq
MIRT1109652	hsa-miR-1260b	CLIP-seq
MIRT1109655	hsa-miR-1280	CLIP-seq
MIRT2561268	hsa-miR-1291	CLIP-seq
MIRT1109658	hsa-miR-1301	CLIP-seq
MIRT1109662	hsa-miR-1827	CLIP-seq
MIRT2561269	hsa-miR-214	CLIP-seq
MIRT2561270	hsa-miR-3120-3p	CLIP-seq
MIRT2561271	hsa-miR-3173-5p	CLIP-seq
MIRT2561272	hsa-miR-328	CLIP-seq
MIRT2561273	hsa-miR-3619-5p	CLIP-seq
MIRT1109679	hsa-miR-3650	CLIP-seq
MIRT2561274	hsa-miR-377	CLIP-seq
MIRT1109685	hsa-miR-384	CLIP-seq
MIRT1109687	hsa-miR-3944-5p	CLIP-seq
MIRT2030536	hsa-miR-4257	CLIP-seq
MIRT2561275	hsa-miR-4258	CLIP-seq
MIRT2561276	hsa-miR-4267	CLIP-seq
MIRT2261286	hsa-miR-4290	CLIP-seq
MIRT2561277	hsa-miR-4428	CLIP-seq
MIRT2261287	hsa-miR-4480	CLIP-seq
MIRT2561278	hsa-miR-451b	CLIP-seq
MIRT1109702	hsa-miR-4649-3p	CLIP-seq
MIRT2561279	hsa-miR-4649-5p	CLIP-seq
MIRT1109704	hsa-miR-4660	CLIP-seq
MIRT1109708	hsa-miR-4698	CLIP-seq
MIRT2561280	hsa-miR-4707-3p	CLIP-seq
MIRT2561281	hsa-miR-4708-3p	CLIP-seq
MIRT2561282	hsa-miR-4722-3p	CLIP-seq
MIRT1109714	hsa-miR-5047	CLIP-seq
MIRT2561283	hsa-miR-532-3p	CLIP-seq
MIRT1109727	hsa-miR-760	CLIP-seq
MIRT2561284	hsa-miR-761	CLIP-seq
MIRT2561285	hsa-miR-766	CLIP-seq
MIRT2561271	hsa-miR-3173-5p	CLIP-seq
MIRT2561274	hsa-miR-377	CLIP-seq
MIRT2561276	hsa-miR-4267	CLIP-seq
MIRT2261286	hsa-miR-4290	CLIP-seq
MIRT2561277	hsa-miR-4428	CLIP-seq
MIRT2561278	hsa-miR-451b	CLIP-seq
MIRT2561281	hsa-miR-4708-3p	CLIP-seq
MIRT2561285	hsa-miR-766	CLIP-seq

Show/Hide all(55)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0001673	Component	Male germ cell nucleus	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	NAS	8537403
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	22328514
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	TAS	8537403
GO:0005515	Function	Protein binding	IPI	8940095, 10559936, 10652353, 15220930, 15660133, 16837009, 17500066, 17853892, 18028908, 19424295, 20133759, 21219645, 32296183, 35914814, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	17512523
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005925	Component	Focal adhesion	IEA
GO:0006468	Process	Protein phosphorylation	IDA	22328514
GO:0006468	Process	Protein phosphorylation	IMP	23633677
GO:0006468	Process	Protein phosphorylation	TAS	8537403
GO:0007165	Process	Signal transduction	TAS	10428028, 10436159
GO:0007266	Process	Rho protein signal transduction	TAS	10436159
GO:0007399	Process	Nervous system development	TAS	8689688
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016607	Component	Nuclear speck	IDA
GO:0016740	Function	Transferase activity	IEA
GO:0030027	Component	Lamellipodium	IEA
GO:0030027	Component	Lamellipodium	ISS
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0030036	Process	Actin cytoskeleton organization	TAS	10428028
GO:0030054	Component	Cell junction	IEA
GO:0031072	Function	Heat shock protein binding	IDA	17512523
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	17512523
GO:0032233	Process	Positive regulation of actin filament bundle assembly	IDA	17512523
GO:0038096	Process	Fc-gamma receptor signaling pathway involved in phagocytosis	TAS
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IBA
GO:0043005	Component	Neuron projection	IEA
GO:0043005	Component	Neuron projection	ISS
GO:0043149	Process	Stress fiber assembly	IEA
GO:0045773	Process	Positive regulation of axon extension	IEA
GO:0045773	Process	Positive regulation of axon extension	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0048675	Process	Axon extension	IEA
GO:0051496	Process	Positive regulation of stress fiber assembly	IBA
GO:0051496	Process	Positive regulation of stress fiber assembly	IEA
GO:0098794	Component	Postsynapse	IDA	25884247
GO:0098794	Component	Postsynapse	IMP	25884247
GO:0098978	Component	Glutamatergic synapse	IDA	25884247
GO:0098978	Component	Glutamatergic synapse	IMP	25884247
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1990948	Function	Ubiquitin ligase inhibitor activity	IDA	17512523

MIM	HGNC	e!Ensembl
601329	6613	ENSG00000106683

Protein

UniProt ID

P53667

Protein name

LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)

Protein function

Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, PubMed:11832213, PubMed:12807904, PubMed:15660

PDB

3S95 , 5HVJ , 5HVK , 5L6W , 5NXC , 6WLY , 7ATS , 7ATU , 7B8W , 8AAU

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00412	LIM	25 → 80	LIM domain	Domain
PF00412	LIM	84 → 142	LIM domain	Domain
PF00595	PDZ	165 → 255	PDZ domain	Domain
PF07714	PK_Tyr_Ser-Thr	339 → 604	Protein tyrosine and serine/threonine kinase	Domain

Tissue specificity

TISSUE SPECIFICITY: Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.

Sequence

MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLS
HQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGD
GDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSV
SIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEID
LLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSID
RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRE
TGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGT
LRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFG
LARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLC
EIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL
EHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD

Sequence length

647

Interactions

View interactions

	KEGG		Reactome
	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Yersinia infection Human immunodeficiency virus 1 infection		Regulation of actin dynamics for phagocytic cup formation Sema3A PAK dependent Axon repulsion RHO GTPases activate PAKs

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Systemic lupus erythematosus	Systemic lupus erythematosus	N/A	N/A	GWAS

Show/Hide Text Mining Associations (45)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Arrhythmias Cardiac	Associate	31560829
Breast Neoplasms	Associate	17559677, 18000399, 19153192, 21219645, 27116935, 31078043, 34079084, 34486491
Carcinoma Ductal Breast	Associate	19153192
Carcinoma Hepatocellular	Associate	26271467
Carcinoma Non Small Cell Lung	Associate	23154546, 25003638, 25975262
Carcinoma Squamous Cell	Associate	25019203
Chromosomal Instability	Associate	17559677, 24642638
Chromosome Aberrations	Stimulate	17559677
Cognition Disorders	Associate	8689688, 8812460
Colonic Neoplasms	Associate	38238555
Colorectal Neoplasms	Associate	28358024, 37193711, 37828981
Disseminated Intravascular Coagulation	Associate	24039253
Drug Related Side Effects and Adverse Reactions	Associate	25359780, 32641387
Esophageal Squamous Cell Carcinoma	Associate	22499122
Fibrocartilaginous embolism	Associate	24441571
Glioblastoma	Associate	23338717, 25237832, 29724193, 33062725, 33649781
Hematologic Neoplasms	Associate	30550596
Hirschsprung Disease	Associate	35322726
HIV Infections	Associate	28381571
Inflammation	Associate	24039253
Kidney Neoplasms	Associate	26540348
Leukemia	Associate	24642638
Leukemia Myeloid Acute	Associate	32591645
Leukemia T Cell	Inhibit	24642638
Lymphatic Metastasis	Associate	32168432
Melanoma	Associate	32196612
Mouth Neoplasms	Associate	30873211
Neoplasm Metastasis	Associate	12821664, 17559677, 21219645, 25003638, 34079084
Neoplasms	Associate	15967107, 17559677, 18000399, 20876278, 21219645, 22689056, 22906279, 24642638, 25003638, 25307528, 26540348, 27116935, 29415725, 30873211, 38189823
Neuroblastoma	Associate	26540348
Neurocognitive Disorders	Associate	37633900
Neurologic Manifestations	Associate	37633900
Ovarian Neoplasms	Associate	22906279
Personality Disorders	Associate	20622363
Pre Eclampsia	Inhibit	25307528
Prostatic Neoplasms	Associate	12821664, 15908432, 17559677, 21219645, 25344584, 25359780, 31389670, 32168432
Prostatitis	Stimulate	12821664
Prostatitis	Associate	21219645, 22689056
Rhabdomyosarcoma	Associate	26540348
Squamous Cell Carcinoma of Head and Neck	Associate	30873211
Stomach Neoplasms	Associate	36316865
Tertiary Lymphoid Structures	Stimulate	32168432
Uterine Cervical Neoplasms	Associate	20622363, 33760158
Vascular Diseases	Associate	8689688
Williams Syndrome	Associate	17827280, 22411788, 25105779, 31204697, 31687737, 37633900, 8689688, 8812460

LIMK1 (LIM domain kinase 1)