ARHGAP5 (Rho GTPase activating protein 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 394 |
| Gene name | Rho GTPase activating protein 5 |
| Gene symbol | ARHGAP5 |
| Synonyms (NCBI Gene) |
GFI2RhoGAP5p190-Bp190BRhoGAP
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| Chromosome | 14 |
| Chromosome location | 14q12 |
| Summary | Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by R |
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miRNA
miRNA information provided by mirtarbase database.
422
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q13017 | |||||||||||||||||||||||||
| Protein name | Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) | |||||||||||||||||||||||||
| Protein function | GTPase-activating protein for Rho family members (PubMed:8537347). | |||||||||||||||||||||||||
| PDB | 2EE4 , 2EE5 , 5U4V | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in skin fibroblasts (at protein level) (PubMed:8537347). {ECO:0000269|PubMed:8537347}. | |||||||||||||||||||||||||
| Sequence |
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| Sequence length | 1502 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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