Gene Gene information from NCBI Gene database.
Entrez ID 3925
Gene name Stathmin 1
Gene symbol STMN1
Synonyms (NCBI Gene)
C1orf215LAP18LagOP18PP17PP19PR22SMN
Chromosome 1
Chromosome location 1p36.11
Summary This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulatio
miRNA miRNA information provided by mirtarbase database.
607
miRTarBase ID miRNA Experiments Reference
MIRT000129 hsa-miR-223-3p -7 18555017
MIRT000129 hsa-miR-223-3p -7 18555017
MIRT000129 hsa-miR-223-3p -7 18555017
MIRT006149 hsa-miR-101-3p Luciferase reporter assayMicroarrayqRT-PCRWestern blot 21915098
MIRT006149 hsa-miR-101-3p Luciferase reporter assayMicroarrayqRT-PCRWestern blot 21915098
Transcription factors Transcription factors information provided by TRRUST V2 database.
5
Transcription factor Regulation Reference
CREB1 Unknown 23000483
EGR1 Unknown 19786090
JUN Activation 15474303
KLF10 Repression 18930345
LYL1 Unknown 23000483
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
39
GO ID Ontology Definition Evidence Reference
GO:0000281 Process Mitotic cytokinesis IEA
GO:0000281 Process Mitotic cytokinesis IMP 25122120
GO:0005515 Function Protein binding IPI 15652749, 21423803, 25416956
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
151442 6510 ENSG00000117632
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P16949
Protein name Stathmin (Leukemia-associated phosphoprotein p18) (Metablastin) (Oncoprotein 18) (Op18) (Phosphoprotein p19) (pp19) (Prosolin) (Protein Pr22) (pp17)
Protein function Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Invol
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00836 Stathmin 5 140 Stathmin family Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is read
Sequence
Sequence length 149
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  MAPK signaling pathway
MicroRNAs in cancer
  Nuclear signaling by ERBB4