LRRC10B (leucine rich repeat containing 10B)

Gene

• Entrez ID: 390205
• Gene name: Leucine rich repeat containing 10B
• Gene symbol: LRRC10B
• Synonyms (NCBI Gene): -
• Chromosome: 11
• Chromosome location: 11q12.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT043349	hsa-miR-331-3p	CLASH	23622248
MIRT1118754	hsa-miR-1262	CLIP-seq
MIRT1118755	hsa-miR-1321	CLIP-seq
MIRT1118756	hsa-miR-146b-3p	CLIP-seq
MIRT1118757	hsa-miR-2861	CLIP-seq
MIRT1118758	hsa-miR-3135	CLIP-seq
MIRT1118759	hsa-miR-3147	CLIP-seq
MIRT1118760	hsa-miR-3173-5p	CLIP-seq
MIRT1118761	hsa-miR-4419a	CLIP-seq
MIRT1118762	hsa-miR-4425	CLIP-seq
MIRT1118763	hsa-miR-4510	CLIP-seq
MIRT1118764	hsa-miR-4701-3p	CLIP-seq
MIRT1118765	hsa-miR-4728-5p	CLIP-seq
MIRT1118766	hsa-miR-4739	CLIP-seq
MIRT1118767	hsa-miR-4756-5p	CLIP-seq
MIRT1118768	hsa-miR-541	CLIP-seq
MIRT1118769	hsa-miR-609	CLIP-seq
MIRT1118770	hsa-miR-654-5p	CLIP-seq
MIRT1118771	hsa-miR-874	CLIP-seq
MIRT2033579	hsa-miR-3157-5p	CLIP-seq
MIRT2033580	hsa-miR-4691-3p	CLIP-seq
MIRT1118759	hsa-miR-3147	CLIP-seq
MIRT2264022	hsa-miR-4421	CLIP-seq
MIRT1118762	hsa-miR-4425	CLIP-seq
MIRT1118765	hsa-miR-4728-5p	CLIP-seq
MIRT2264023	hsa-miR-676	CLIP-seq
MIRT2563166	hsa-miR-1305	CLIP-seq
MIRT2563167	hsa-miR-2277-3p	CLIP-seq
MIRT2563168	hsa-miR-607	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A6NIK2
• Protein name: Leucine-rich repeat-containing protein 10B
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	67 → 125	Leucine rich repeat	Repeat
  PF13855	LRR_8	90 → 148	Leucine rich repeat	Repeat

• Sequence:

  MGIAESTPDELPSDAEEQLRSGDQQLELSGRRLRRLPSAVCALSRLQKLYVSGTGLRELP
  EEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGGNRLLALPADFAQLQSLRCLWI
  EGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPPALLR
  MGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPPRVADTVFLVGEGAVERMAER
  DEPTPRPPPRRPARAFEDEEEEDLLIGGAGSRALGAPGGSFRALEAAPGLGT

• Sequence length: 292

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESSENTIAL HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations