Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	389170
Gene name Gene Name - the full gene name approved by the HGNC.	Leucine, glutamate and lysine rich 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LEKR1
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q25.31

Show/Hide all(47)

miRTarBase ID	miRNA	Experiments
MIRT1107244	hsa-miR-1252	CLIP-seq
MIRT1107245	hsa-miR-214	CLIP-seq
MIRT1107246	hsa-miR-298	CLIP-seq
MIRT1107247	hsa-miR-300	CLIP-seq
MIRT1107248	hsa-miR-3619-5p	CLIP-seq
MIRT1107249	hsa-miR-3678-3p	CLIP-seq
MIRT1107250	hsa-miR-381	CLIP-seq
MIRT1107251	hsa-miR-4282	CLIP-seq
MIRT1107252	hsa-miR-4457	CLIP-seq
MIRT1107253	hsa-miR-4528	CLIP-seq
MIRT1107254	hsa-miR-4666-3p	CLIP-seq
MIRT1107255	hsa-miR-4670-3p	CLIP-seq
MIRT1107256	hsa-miR-4760-3p	CLIP-seq
MIRT1107257	hsa-miR-4802-5p	CLIP-seq
MIRT1107258	hsa-miR-513b	CLIP-seq
MIRT1107259	hsa-miR-548c-3p	CLIP-seq
MIRT1107260	hsa-miR-570	CLIP-seq
MIRT1107261	hsa-miR-590-3p	CLIP-seq
MIRT1107262	hsa-miR-657	CLIP-seq
MIRT1107263	hsa-miR-664	CLIP-seq
MIRT1107264	hsa-miR-761	CLIP-seq
MIRT1107265	hsa-miR-944	CLIP-seq
MIRT2260526	hsa-miR-494	CLIP-seq
MIRT2452905	hsa-miR-186	CLIP-seq
MIRT2452906	hsa-miR-3133	CLIP-seq
MIRT2452907	hsa-miR-376a	CLIP-seq
MIRT2452908	hsa-miR-376b	CLIP-seq
MIRT2452909	hsa-miR-4509	CLIP-seq
MIRT2452910	hsa-miR-4744	CLIP-seq
MIRT2452911	hsa-miR-610	CLIP-seq
MIRT2452905	hsa-miR-186	CLIP-seq
MIRT2452906	hsa-miR-3133	CLIP-seq
MIRT2452907	hsa-miR-376a	CLIP-seq
MIRT2452908	hsa-miR-376b	CLIP-seq
MIRT2452909	hsa-miR-4509	CLIP-seq
MIRT2452910	hsa-miR-4744	CLIP-seq
MIRT2452911	hsa-miR-610	CLIP-seq
MIRT1107247	hsa-miR-300	CLIP-seq
MIRT1107250	hsa-miR-381	CLIP-seq
MIRT1107254	hsa-miR-4666-3p	CLIP-seq
MIRT1107259	hsa-miR-548c-3p	CLIP-seq
MIRT1107261	hsa-miR-590-3p	CLIP-seq
MIRT1107247	hsa-miR-300	CLIP-seq
MIRT1107250	hsa-miR-381	CLIP-seq
MIRT1107254	hsa-miR-4666-3p	CLIP-seq
MIRT1107259	hsa-miR-548c-3p	CLIP-seq
MIRT1107261	hsa-miR-590-3p	CLIP-seq

MIM	HGNC	e!Ensembl
613536	33765	ENSG00000197980

Protein

UniProt ID

Q6ZMV7

Protein name

Protein LEKR1

Family and domains

Sequence

MLLKEKEDSLMTCQQIYKALQEELTVKEKQEEDIKRRINLAENELEITKTLLNQTREEVL
TLKNERELMLISHQKSIEQLQETLRQKLLSDDNWKEKIEAELAKERAQHLVEFEEQALLF
KEETKLQLDIEKEKHQDVIQKYKKEQEELQMKISDLITGATRDLRQEVTTLKEKLHKSHI
RYTEESNSKEKEIENLKNLVAEFESRLKKEIDSNDSVSENLRKEMEQKSDELKRVMLAQT
QLIEQFNQSQEENTFLQETVRRECEERFELTEALSQAREQLLELSKLRGSLPFSPCSLSK
GSLTSPAAAVSNHGERSLARLNSEKGIQIPNLRGVSKPTTFPTSDKPKRVRSGVPILPQP
HPPRGGASSANETRQRLAAILRRRRSQQ

Sequence length

388

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	29059683

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Evidence	Source
Unknown
Breast cancer	Breast cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients	GWAS, CBGDA
Psoriasis	Psoriasis		GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Ovarian Epithelial	Associate	27378695

LEKR1 (leucine, glutamate and lysine rich 1)