PLSCR5 (phospholipid scramblase family member 5)

Gene

• Entrez ID: 389158
• Gene name: Phospholipid scramblase family member 5
• Gene symbol: PLSCR5
• Synonyms (NCBI Gene): -
• Chromosome: 3
• Chromosome location: 3q24

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1243313	hsa-miR-181a	CLIP-seq
MIRT1243314	hsa-miR-181b	CLIP-seq
MIRT1243315	hsa-miR-181c	CLIP-seq
MIRT1243316	hsa-miR-181d	CLIP-seq
MIRT1243317	hsa-miR-3613-3p	CLIP-seq
MIRT1243318	hsa-miR-4262	CLIP-seq
MIRT1243319	hsa-miR-543	CLIP-seq
MIRT2595922	hsa-miR-1290	CLIP-seq
MIRT2595923	hsa-miR-203	CLIP-seq
MIRT2595924	hsa-miR-544	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IBA
GO:0017121	Process	Plasma membrane phospholipid scrambling	IBA
GO:0017121	Process	Plasma membrane phospholipid scrambling	IEA
GO:0017128	Function	Phospholipid scramblase activity	IBA
GO:0017128	Function	Phospholipid scramblase activity	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: A0PG75
• Protein name: Phospholipid scramblase family member 5
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03803	Scramblase	44 → 266	Scramblase	Domain

• Sequence:

  MASKDAQNQRRGLPGFLPGAPDPDQSLPASSNPGNQAWQLSLPLPSSFLPTVSLPPGLEY
  LSQLDLIIIHQQVELLGMILGTETSNKYEIKNSLGQRIYFAVEESICFNRTFCSTLRSCT
  LRITDNSGREVITVNRPLRCNSCWCPCYLQELEIQAPPGTIVGYVTQKWDPFLPKFTIQN
  ANKEDILKIVGPCVTCGCFGDVDFEVKTINEKLTIGKISKYWSGFVNDVFTNADNFGIHV
  PADLDVTVKAAMIGACFLFDFMFFEHSLAGL

• Sequence length: 271

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BARRETT'S ESOPHAGUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
STROKE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations