SP5 (Sp5 transcription factor)

Gene

• Entrez ID: 389058
• Gene name: Sp5 transcription factor
• Gene symbol: SP5
• Synonyms (NCBI Gene): -
• Chromosome: 2
• Chromosome location: 2q31.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1381507	hsa-miR-103a	CLIP-seq
MIRT1381508	hsa-miR-107	CLIP-seq
MIRT1381509	hsa-miR-125a-5p	CLIP-seq
MIRT1381510	hsa-miR-125b	CLIP-seq
MIRT1381511	hsa-miR-1293	CLIP-seq
MIRT1381512	hsa-miR-142-3p	CLIP-seq
MIRT1381513	hsa-miR-15a	CLIP-seq
MIRT1381514	hsa-miR-15b	CLIP-seq
MIRT1381515	hsa-miR-16	CLIP-seq
MIRT1381516	hsa-miR-193a-5p	CLIP-seq
MIRT1381517	hsa-miR-195	CLIP-seq
MIRT1381518	hsa-miR-214	CLIP-seq
MIRT1381519	hsa-miR-300	CLIP-seq
MIRT1381520	hsa-miR-3179	CLIP-seq
MIRT1381521	hsa-miR-3202	CLIP-seq
MIRT1381522	hsa-miR-323-5p	CLIP-seq
MIRT1381523	hsa-miR-337-3p	CLIP-seq
MIRT1381524	hsa-miR-3619-5p	CLIP-seq
MIRT1381525	hsa-miR-3685	CLIP-seq
MIRT1381526	hsa-miR-381	CLIP-seq
MIRT1381527	hsa-miR-384	CLIP-seq
MIRT1381528	hsa-miR-3922-5p	CLIP-seq
MIRT1381529	hsa-miR-424	CLIP-seq
MIRT1381530	hsa-miR-4277	CLIP-seq
MIRT1381531	hsa-miR-4281	CLIP-seq
MIRT1381532	hsa-miR-4291	CLIP-seq
MIRT1381533	hsa-miR-4310	CLIP-seq
MIRT1381534	hsa-miR-4319	CLIP-seq
MIRT1381535	hsa-miR-4483	CLIP-seq
MIRT1381536	hsa-miR-4497	CLIP-seq
MIRT1381537	hsa-miR-4666-3p	CLIP-seq
MIRT1381538	hsa-miR-4728-5p	CLIP-seq
MIRT1381539	hsa-miR-4738-3p	CLIP-seq
MIRT1381540	hsa-miR-4747-5p	CLIP-seq
MIRT1381541	hsa-miR-4753-5p	CLIP-seq
MIRT1381542	hsa-miR-486-5p	CLIP-seq
MIRT1381543	hsa-miR-497	CLIP-seq
MIRT1381544	hsa-miR-548g	CLIP-seq
MIRT1381545	hsa-miR-615-5p	CLIP-seq
MIRT1381546	hsa-miR-624	CLIP-seq
MIRT1381547	hsa-miR-761	CLIP-seq
MIRT1381548	hsa-miR-922	CLIP-seq
MIRT2114183	hsa-miR-4772-3p	CLIP-seq
MIRT2114184	hsa-miR-891b	CLIP-seq
MIRT1381509	hsa-miR-125a-5p	CLIP-seq
MIRT1381510	hsa-miR-125b	CLIP-seq
MIRT2337107	hsa-miR-4287	CLIP-seq
MIRT1381534	hsa-miR-4319	CLIP-seq
MIRT2337108	hsa-miR-4469	CLIP-seq
MIRT2337109	hsa-miR-4685-3p	CLIP-seq
MIRT2337110	hsa-miR-4732-3p	CLIP-seq
MIRT2337111	hsa-miR-670	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0036342	Process	Post-anal tail morphogenesis	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0060349	Process	Bone morphogenesis	IEA

Other IDs

• MIM: 609391
• HGNC: 14529
• e!Ensembl: ENSG00000204335

Protein

• UniProt ID: Q6BEB4
• Protein name: Transcription factor Sp5
• Protein function: Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	296 → 320	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	326 → 350	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	356 → 378	Zinc finger, C2H2 type	Domain

• Sequence:

  MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYD
  PALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPS
  YPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSP
  NPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAAAAAAAAAALQRGL
  VLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHV
  PGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPE
  CGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL

• Sequence length: 398