CAPN8 (calpain 8)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
388743
Gene name Gene Name - the full gene name approved by the HGNC.
Calpain 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CAPN8
Synonyms (NCBI Gene) Gene synonyms aliases
nCL-2
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q41
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all(8)
miRTarBase ID miRNA Experiments Reference
MIRT2193425 hsa-miR-3123 CLIP-seq
MIRT2193426 hsa-miR-3154 CLIP-seq
MIRT2193427 hsa-miR-3179 CLIP-seq
MIRT2193428 hsa-miR-3674 CLIP-seq
MIRT2193429 hsa-miR-3925-5p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all(12)
GO ID Ontology Definition Evidence Reference
GO:0004198 Function Calcium-dependent cysteine-type endopeptidase activity IBA
GO:0004198 Function Calcium-dependent cysteine-type endopeptidase activity IEA
GO:0005509 Function Calcium ion binding IEA
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
618777 1485 ENSG00000203697
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID A6NHC0
Protein name Calpain-8 (EC 3.4.22.53) (New calpain 2) (nCL-2) (Stomach-specific M-type calpain)
Protein function Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves t
PDB 2NQA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00648 Peptidase_C2 46 → 342 Calpain family cysteine protease Family
PF01067 Calpain_III 363 → 504 Calpain large subunit, domain III Domain
Tissue specificity TISSUE SPECIFICITY: Stomach.
Sequence
Sequence length 703
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  Reactome
    Degradation of the extracellular matrix
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