CAPN8 (calpain 8)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID 388743
Gene name Calpain 8
Gene symbol CAPN8
Synonyms (NCBI Gene)
nCL-2
Chromosome 1
Chromosome location 1q41
miRNA miRNA information provided by mirtarbase database.
8
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all (8)
miRTarBase ID miRNA Experiments Reference
MIRT2193425 hsa-miR-3123 CLIP-seq
MIRT2193426 hsa-miR-3154 CLIP-seq
MIRT2193427 hsa-miR-3179 CLIP-seq
MIRT2193428 hsa-miR-3674 CLIP-seq
MIRT2193429 hsa-miR-3925-5p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
Gene miRNA Gene ontology Other IDs Protein Pathways
Show/Hide all (12)
GO ID Ontology Definition Evidence Reference
GO:0004198 Function Calcium-dependent cysteine-type endopeptidase activity IBA
GO:0004198 Function Calcium-dependent cysteine-type endopeptidase activity IEA
GO:0005509 Function Calcium ion binding IEA
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
618777 1485 ENSG00000203697
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A6NHC0
Protein name Calpain-8 (EC 3.4.22.53) (New calpain 2) (nCL-2) (Stomach-specific M-type calpain)
Protein function Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves t
PDB 2NQA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00648 Peptidase_C2 46 → 342 Calpain family cysteine protease Family
PF01067 Calpain_III 363 → 504 Calpain large subunit, domain III Domain
Tissue specificity TISSUE SPECIFICITY: Stomach.
Sequence
Sequence length 703
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways
  Reactome
    Degradation of the extracellular matrix