DIPK1A (divergent protein kinase domain 1A)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
388650
Gene name Gene Name - the full gene name approved by the HGNC.
Divergent protein kinase domain 1A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
DIPK1A
Synonyms (NCBI Gene) Gene synonyms aliases
FAM69A
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p22.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown. Alternatively spliced transcript variants encoding multiple isof
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(4)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32814053
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0016020 Component Membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
614542 32213 ENSG00000154511
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q5T7M9
Protein name Divergent protein kinase domain 1A (Protein FAM69A)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14875 PIP49_N 19 → 176 N-term cysteine-rich ER, FAM69 Domain
PF12260 PIP49_C 194 → 396 Protein-kinase domain of FAM69 Family
Sequence
Sequence length 428
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (2)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Multiple Sclerosis Multiple sclerosis N/A N/A GWAS
Prostate cancer Prostate cancer N/A N/A GWAS
Show/Hide Text Mining Associations (4)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Multiple Sclerosis Associate 20087403
Myasthenia Gravis Associate 30696470
Neurologic Manifestations Associate 23840464
Ophthalmoplegia Associate 30696470