ZNF470 (zinc finger protein 470)

Gene

• Entrez ID: 388566
• Gene name: Zinc finger protein 470
• Gene symbol: ZNF470
• Synonyms (NCBI Gene): CZF-1
• Chromosome: 19
• Chromosome location: 19q13.43

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT723378	hsa-miR-1911-3p	HITS-CLIP	19536157
MIRT723377	hsa-miR-6753-5p	HITS-CLIP	19536157
MIRT723376	hsa-miR-3183	HITS-CLIP	19536157
MIRT723375	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT723374	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT723373	hsa-miR-3124-3p	HITS-CLIP	19536157
MIRT723372	hsa-miR-1206	HITS-CLIP	19536157
MIRT723371	hsa-miR-6853-3p	HITS-CLIP	19536157
MIRT723370	hsa-miR-452-3p	HITS-CLIP	19536157
MIRT723369	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT723368	hsa-miR-6780a-3p	HITS-CLIP	19536157
MIRT723367	hsa-miR-6881-3p	HITS-CLIP	19536157
MIRT723366	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT723365	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT723364	hsa-miR-1238-3p	HITS-CLIP	19536157
MIRT723363	hsa-miR-375	HITS-CLIP	19536157
MIRT723362	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT723378	hsa-miR-1911-3p	HITS-CLIP	19536157
MIRT723377	hsa-miR-6753-5p	HITS-CLIP	19536157
MIRT723376	hsa-miR-3183	HITS-CLIP	19536157
MIRT723375	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT723374	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT723373	hsa-miR-3124-3p	HITS-CLIP	19536157
MIRT723372	hsa-miR-1206	HITS-CLIP	19536157
MIRT723371	hsa-miR-6853-3p	HITS-CLIP	19536157
MIRT723370	hsa-miR-452-3p	HITS-CLIP	19536157
MIRT723369	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT723368	hsa-miR-6780a-3p	HITS-CLIP	19536157
MIRT723367	hsa-miR-6881-3p	HITS-CLIP	19536157
MIRT723366	hsa-miR-4684-5p	HITS-CLIP	19536157
MIRT723365	hsa-miR-670-3p	HITS-CLIP	19536157
MIRT723364	hsa-miR-1238-3p	HITS-CLIP	19536157
MIRT723363	hsa-miR-375	HITS-CLIP	19536157
MIRT723362	hsa-miR-6739-3p	HITS-CLIP	19536157
MIRT1525810	hsa-miR-1231	CLIP-seq
MIRT1525811	hsa-miR-1343	CLIP-seq
MIRT1525812	hsa-miR-142-5p	CLIP-seq
MIRT1525813	hsa-miR-181a	CLIP-seq
MIRT1525814	hsa-miR-181b	CLIP-seq
MIRT1525815	hsa-miR-181c	CLIP-seq
MIRT1525816	hsa-miR-181d	CLIP-seq
MIRT1525817	hsa-miR-197	CLIP-seq
MIRT1525818	hsa-miR-200b	CLIP-seq
MIRT1525819	hsa-miR-200c	CLIP-seq
MIRT1525820	hsa-miR-203	CLIP-seq
MIRT1525821	hsa-miR-2113	CLIP-seq
MIRT1525822	hsa-miR-217	CLIP-seq
MIRT1525823	hsa-miR-2909	CLIP-seq
MIRT1525824	hsa-miR-3065-5p	CLIP-seq
MIRT1525825	hsa-miR-3117-3p	CLIP-seq
MIRT1525826	hsa-miR-3147	CLIP-seq
MIRT1525827	hsa-miR-3162-5p	CLIP-seq
MIRT1525828	hsa-miR-3169	CLIP-seq
MIRT1525829	hsa-miR-3170	CLIP-seq
MIRT1525830	hsa-miR-320a	CLIP-seq
MIRT1525831	hsa-miR-320b	CLIP-seq
MIRT1525832	hsa-miR-320c	CLIP-seq
MIRT1525833	hsa-miR-320d	CLIP-seq
MIRT1525834	hsa-miR-323b-3p	CLIP-seq
MIRT1525835	hsa-miR-330-3p	CLIP-seq
MIRT1525836	hsa-miR-338-5p	CLIP-seq
MIRT1525837	hsa-miR-340	CLIP-seq
MIRT1525838	hsa-miR-3545-3p	CLIP-seq
MIRT1525839	hsa-miR-3684	CLIP-seq
MIRT1525840	hsa-miR-3692	CLIP-seq
MIRT1525841	hsa-miR-378g	CLIP-seq
MIRT1525842	hsa-miR-3919	CLIP-seq
MIRT1525843	hsa-miR-3926	CLIP-seq
MIRT1525844	hsa-miR-3973	CLIP-seq
MIRT1525845	hsa-miR-421	CLIP-seq
MIRT1525846	hsa-miR-4262	CLIP-seq
MIRT1525847	hsa-miR-4288	CLIP-seq
MIRT1525848	hsa-miR-429	CLIP-seq
MIRT1525849	hsa-miR-4303	CLIP-seq
MIRT1525850	hsa-miR-4422	CLIP-seq
MIRT1525851	hsa-miR-4425	CLIP-seq
MIRT1525852	hsa-miR-4429	CLIP-seq
MIRT1525853	hsa-miR-4437	CLIP-seq
MIRT1525854	hsa-miR-4484	CLIP-seq
MIRT1525855	hsa-miR-4528	CLIP-seq
MIRT1525856	hsa-miR-4536	CLIP-seq
MIRT1525857	hsa-miR-4633-5p	CLIP-seq
MIRT1525858	hsa-miR-4652-3p	CLIP-seq
MIRT1525859	hsa-miR-4674	CLIP-seq
MIRT1525860	hsa-miR-4682	CLIP-seq
MIRT1525861	hsa-miR-4686	CLIP-seq
MIRT1525862	hsa-miR-4711-5p	CLIP-seq
MIRT1525863	hsa-miR-4724-5p	CLIP-seq
MIRT1525864	hsa-miR-4753-5p	CLIP-seq
MIRT1525865	hsa-miR-4756-3p	CLIP-seq
MIRT1525866	hsa-miR-4759	CLIP-seq
MIRT1525867	hsa-miR-4775	CLIP-seq
MIRT1525868	hsa-miR-4781-3p	CLIP-seq
MIRT1525869	hsa-miR-532-5p	CLIP-seq
MIRT1525870	hsa-miR-548an	CLIP-seq
MIRT1525871	hsa-miR-548l	CLIP-seq
MIRT1525872	hsa-miR-590-3p	CLIP-seq
MIRT1525873	hsa-miR-592	CLIP-seq
MIRT1525874	hsa-miR-599	CLIP-seq
MIRT1525875	hsa-miR-629	CLIP-seq
MIRT1525876	hsa-miR-632	CLIP-seq
MIRT1525877	hsa-miR-651	CLIP-seq
MIRT1525878	hsa-miR-668	CLIP-seq
MIRT1525879	hsa-miR-888	CLIP-seq
MIRT2158912	hsa-miR-106a	CLIP-seq
MIRT2158913	hsa-miR-106b	CLIP-seq
MIRT2158914	hsa-miR-1292	CLIP-seq
MIRT2158915	hsa-miR-129-5p	CLIP-seq
MIRT2158916	hsa-miR-1302	CLIP-seq
MIRT2158917	hsa-miR-138	CLIP-seq
MIRT2158918	hsa-miR-150	CLIP-seq
MIRT2158919	hsa-miR-17	CLIP-seq
MIRT2158920	hsa-miR-185	CLIP-seq
MIRT1525817	hsa-miR-197	CLIP-seq
MIRT1525820	hsa-miR-203	CLIP-seq
MIRT2158921	hsa-miR-20a	CLIP-seq
MIRT2158922	hsa-miR-20b	CLIP-seq
MIRT2158923	hsa-miR-214	CLIP-seq
MIRT2158924	hsa-miR-302a	CLIP-seq
MIRT2158925	hsa-miR-302b	CLIP-seq
MIRT2158926	hsa-miR-302c	CLIP-seq
MIRT2158927	hsa-miR-302d	CLIP-seq
MIRT2158928	hsa-miR-302e	CLIP-seq
MIRT2158929	hsa-miR-3074-3p	CLIP-seq
MIRT2158930	hsa-miR-3199	CLIP-seq
MIRT2158931	hsa-miR-323-5p	CLIP-seq
MIRT1525836	hsa-miR-338-5p	CLIP-seq
MIRT2158932	hsa-miR-3617	CLIP-seq
MIRT2158933	hsa-miR-3619-5p	CLIP-seq
MIRT2158934	hsa-miR-3674	CLIP-seq
MIRT2158935	hsa-miR-372	CLIP-seq
MIRT2158936	hsa-miR-373	CLIP-seq
MIRT2158937	hsa-miR-3907	CLIP-seq
MIRT1525842	hsa-miR-3919	CLIP-seq
MIRT2158938	hsa-miR-4260	CLIP-seq
MIRT2158939	hsa-miR-4291	CLIP-seq
MIRT2158940	hsa-miR-4298	CLIP-seq
MIRT1525849	hsa-miR-4303	CLIP-seq
MIRT2158941	hsa-miR-4306	CLIP-seq
MIRT2158942	hsa-miR-4310	CLIP-seq
MIRT1525850	hsa-miR-4422	CLIP-seq
MIRT2158943	hsa-miR-4438	CLIP-seq
MIRT2158944	hsa-miR-4456	CLIP-seq
MIRT2158945	hsa-miR-4471	CLIP-seq
MIRT2158946	hsa-miR-4491	CLIP-seq
MIRT2158947	hsa-miR-4644	CLIP-seq
MIRT2158948	hsa-miR-4657	CLIP-seq
MIRT1525860	hsa-miR-4682	CLIP-seq
MIRT2158949	hsa-miR-4716-5p	CLIP-seq
MIRT2158950	hsa-miR-4731-5p	CLIP-seq
MIRT2158951	hsa-miR-4732-5p	CLIP-seq
MIRT2158952	hsa-miR-4742-3p	CLIP-seq
MIRT1525865	hsa-miR-4756-3p	CLIP-seq
MIRT2158953	hsa-miR-5095	CLIP-seq
MIRT2158954	hsa-miR-5096	CLIP-seq
MIRT2158955	hsa-miR-512-3p	CLIP-seq
MIRT2158956	hsa-miR-519d	CLIP-seq
MIRT2158957	hsa-miR-520a-3p	CLIP-seq
MIRT2158958	hsa-miR-520b	CLIP-seq
MIRT2158959	hsa-miR-520c-3p	CLIP-seq
MIRT2158960	hsa-miR-520d-3p	CLIP-seq
MIRT2158961	hsa-miR-520e	CLIP-seq
MIRT2158962	hsa-miR-520g	CLIP-seq
MIRT2158963	hsa-miR-520h	CLIP-seq
MIRT1525869	hsa-miR-532-5p	CLIP-seq
MIRT2158964	hsa-miR-541	CLIP-seq
MIRT2158965	hsa-miR-548c-3p	CLIP-seq
MIRT2158966	hsa-miR-641	CLIP-seq
MIRT2158967	hsa-miR-654-5p	CLIP-seq
MIRT2158968	hsa-miR-761	CLIP-seq
MIRT2158969	hsa-miR-876-3p	CLIP-seq
MIRT2158970	hsa-miR-922	CLIP-seq
MIRT2158971	hsa-miR-93	CLIP-seq
MIRT2158912	hsa-miR-106a	CLIP-seq
MIRT2158913	hsa-miR-106b	CLIP-seq
MIRT2378311	hsa-miR-1200	CLIP-seq
MIRT2378312	hsa-miR-1236	CLIP-seq
MIRT2378313	hsa-miR-1284	CLIP-seq
MIRT2378314	hsa-miR-1291	CLIP-seq
MIRT2158914	hsa-miR-1292	CLIP-seq
MIRT2158915	hsa-miR-129-5p	CLIP-seq
MIRT1525811	hsa-miR-1343	CLIP-seq
MIRT2158917	hsa-miR-138	CLIP-seq
MIRT2158918	hsa-miR-150	CLIP-seq
MIRT2158919	hsa-miR-17	CLIP-seq
MIRT1525813	hsa-miR-181a	CLIP-seq
MIRT1525814	hsa-miR-181b	CLIP-seq
MIRT1525815	hsa-miR-181c	CLIP-seq
MIRT1525816	hsa-miR-181d	CLIP-seq
MIRT1525817	hsa-miR-197	CLIP-seq
MIRT2378315	hsa-miR-1976	CLIP-seq
MIRT2158921	hsa-miR-20a	CLIP-seq
MIRT2158922	hsa-miR-20b	CLIP-seq
MIRT2158924	hsa-miR-302a	CLIP-seq
MIRT2158925	hsa-miR-302b	CLIP-seq
MIRT2158926	hsa-miR-302c	CLIP-seq
MIRT2158927	hsa-miR-302d	CLIP-seq
MIRT2158928	hsa-miR-302e	CLIP-seq
MIRT1525825	hsa-miR-3117-3p	CLIP-seq
MIRT2378316	hsa-miR-3157-5p	CLIP-seq
MIRT1525828	hsa-miR-3169	CLIP-seq
MIRT1525829	hsa-miR-3170	CLIP-seq
MIRT2158930	hsa-miR-3199	CLIP-seq
MIRT2378317	hsa-miR-328	CLIP-seq
MIRT2378318	hsa-miR-3670	CLIP-seq
MIRT2158934	hsa-miR-3674	CLIP-seq
MIRT2378319	hsa-miR-370	CLIP-seq
MIRT2158935	hsa-miR-372	CLIP-seq
MIRT2158936	hsa-miR-373	CLIP-seq
MIRT1525841	hsa-miR-378g	CLIP-seq
MIRT2158937	hsa-miR-3907	CLIP-seq
MIRT2378320	hsa-miR-3934	CLIP-seq
MIRT2378321	hsa-miR-3977	CLIP-seq
MIRT2158938	hsa-miR-4260	CLIP-seq
MIRT1525846	hsa-miR-4262	CLIP-seq
MIRT2378322	hsa-miR-4273	CLIP-seq
MIRT2378323	hsa-miR-4324	CLIP-seq
MIRT1525853	hsa-miR-4437	CLIP-seq
MIRT2158943	hsa-miR-4438	CLIP-seq
MIRT2158944	hsa-miR-4456	CLIP-seq
MIRT2158945	hsa-miR-4471	CLIP-seq
MIRT1525859	hsa-miR-4674	CLIP-seq
MIRT2158949	hsa-miR-4716-5p	CLIP-seq
MIRT2378324	hsa-miR-4717-3p	CLIP-seq
MIRT2158950	hsa-miR-4731-5p	CLIP-seq
MIRT2158951	hsa-miR-4732-5p	CLIP-seq
MIRT2158952	hsa-miR-4742-3p	CLIP-seq
MIRT1525866	hsa-miR-4759	CLIP-seq
MIRT2378325	hsa-miR-4763-5p	CLIP-seq
MIRT1525867	hsa-miR-4775	CLIP-seq
MIRT2158953	hsa-miR-5095	CLIP-seq
MIRT2158954	hsa-miR-5096	CLIP-seq
MIRT2158955	hsa-miR-512-3p	CLIP-seq
MIRT2158956	hsa-miR-519d	CLIP-seq
MIRT2158957	hsa-miR-520a-3p	CLIP-seq
MIRT2158958	hsa-miR-520b	CLIP-seq
MIRT2158959	hsa-miR-520c-3p	CLIP-seq
MIRT2158960	hsa-miR-520d-3p	CLIP-seq
MIRT2158961	hsa-miR-520e	CLIP-seq
MIRT2158962	hsa-miR-520g	CLIP-seq
MIRT2158963	hsa-miR-520h	CLIP-seq
MIRT2158964	hsa-miR-541	CLIP-seq
MIRT2378326	hsa-miR-544b	CLIP-seq
MIRT2378327	hsa-miR-552	CLIP-seq
MIRT1525872	hsa-miR-590-3p	CLIP-seq
MIRT2378328	hsa-miR-642a	CLIP-seq
MIRT2158967	hsa-miR-654-5p	CLIP-seq
MIRT2158969	hsa-miR-876-3p	CLIP-seq
MIRT2158971	hsa-miR-93	CLIP-seq
MIRT2378311	hsa-miR-1200	CLIP-seq
MIRT2378323	hsa-miR-4324	CLIP-seq
MIRT2378326	hsa-miR-544b	CLIP-seq
MIRT2397577	hsa-miR-659	CLIP-seq
MIRT2670631	hsa-miR-1271	CLIP-seq
MIRT2670632	hsa-miR-182	CLIP-seq
MIRT2670633	hsa-miR-2052	CLIP-seq
MIRT1525825	hsa-miR-3117-3p	CLIP-seq
MIRT1525828	hsa-miR-3169	CLIP-seq
MIRT2670634	hsa-miR-3177-5p	CLIP-seq
MIRT2378320	hsa-miR-3934	CLIP-seq
MIRT2670635	hsa-miR-4307	CLIP-seq
MIRT2670636	hsa-miR-4735-5p	CLIP-seq
MIRT1525866	hsa-miR-4759	CLIP-seq
MIRT2670637	hsa-miR-4794	CLIP-seq
MIRT2378327	hsa-miR-552	CLIP-seq
MIRT2670638	hsa-miR-767-5p	CLIP-seq
MIRT2670639	hsa-miR-96	CLIP-seq
MIRT2670631	hsa-miR-1271	CLIP-seq
MIRT2670632	hsa-miR-182	CLIP-seq
MIRT2696051	hsa-miR-204	CLIP-seq
MIRT2670633	hsa-miR-2052	CLIP-seq
MIRT2696052	hsa-miR-211	CLIP-seq
MIRT1525824	hsa-miR-3065-5p	CLIP-seq
MIRT1525825	hsa-miR-3117-3p	CLIP-seq
MIRT1525828	hsa-miR-3169	CLIP-seq
MIRT2670634	hsa-miR-3177-5p	CLIP-seq
MIRT2378320	hsa-miR-3934	CLIP-seq
MIRT2696053	hsa-miR-3938	CLIP-seq
MIRT2670635	hsa-miR-4307	CLIP-seq
MIRT2696054	hsa-miR-4755-5p	CLIP-seq
MIRT1525866	hsa-miR-4759	CLIP-seq
MIRT2696055	hsa-miR-4780	CLIP-seq
MIRT2670637	hsa-miR-4794	CLIP-seq
MIRT2378327	hsa-miR-552	CLIP-seq
MIRT2696056	hsa-miR-623	CLIP-seq
MIRT2670638	hsa-miR-767-5p	CLIP-seq
MIRT2670639	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 620441
• HGNC: 22220
• e!Ensembl: ENSG00000197016

Protein

• UniProt ID: Q6ECI4
• Protein name: Zinc finger protein 470 (Chondrogenesis zinc finger protein 1) (CZF-1)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	22 → 63	KRAB box	Family
  PF00096	zf-C2H2	228 → 250	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	256 → 278	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	284 → 306	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	312 → 334	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	340 → 362	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	368 → 391	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	425 → 447	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	453 → 475	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	481 → 503	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	509 → 531	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	537 → 559	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	565 → 587	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	621 → 643	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	649 → 671	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	677 → 699	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in testis. Very low expression in thymus. No expression in other tissues tested. Expressed in a differentiation stage-specific manner in mesenchymal chondrogenic progenitor cells. {ECO:0000269|PubMed:15302581}.
• Sequence:

  MKSQEEVEVAGIKLCKAMSLGSVTFTDVAIDFSQDEWEWLNLAQRSLYKKVMLENYRNLV
  SVGLCISKPDVISLLEQEKDPWVIKGGMNRGLCPDLECVWVTKSLSLNQDIYEEKLPPAI
  IMERLKSYDLECSTLGKNWKCEDLFERELVNQKTHFRQETITHIDTLIEKRDHSNKSGTV
  FHLNTLSYIKQIFPMEERIFNFHTDKKSLKTHSVVKKHKQDRGEKKLLKCNDCEKIFSKI
  STLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGEKPFECTECGKAFSQNAHLV
  QHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRR
  IHTGKRPYECIDCGKAFRQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKRTHT
  GERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKP
  YECKECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTGEKPYECK
  ECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECLECGK
  AFRQRASLICHQRCHTGEKPYECNVCGKAFSHRKSLTLHQRIHTGEKPYECKECSKAFSQ
  VAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRIHTGESSVILSSALPYHQVL

• Sequence length: 717

Pathways

Reactome:

Generic Transcription Pathway

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Melanoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations