Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	388558
Gene name	Zinc finger protein 808
Gene symbol	ZNF808
Synonyms (NCBI Gene)	PAGEN3
Chromosome	19
Chromosome location	19q13.41

Show/Hide all (65)

miRTarBase ID	miRNA	Experiments
MIRT1540735	hsa-miR-1294	CLIP-seq
MIRT1540736	hsa-miR-1976	CLIP-seq
MIRT1540737	hsa-miR-3064-3p	CLIP-seq
MIRT1540738	hsa-miR-3200-3p	CLIP-seq
MIRT1540739	hsa-miR-3545-3p	CLIP-seq
MIRT1540740	hsa-miR-3925-3p	CLIP-seq
MIRT1540741	hsa-miR-4316	CLIP-seq
MIRT1540742	hsa-miR-4502	CLIP-seq
MIRT1540743	hsa-miR-450b-5p	CLIP-seq
MIRT1540744	hsa-miR-4696	CLIP-seq
MIRT1540745	hsa-miR-4712-5p	CLIP-seq
MIRT1540746	hsa-miR-4715-3p	CLIP-seq
MIRT1540747	hsa-miR-4768-5p	CLIP-seq
MIRT1540748	hsa-miR-766	CLIP-seq
MIRT1540749	hsa-miR-770-5p	CLIP-seq
MIRT2163266	hsa-miR-1246	CLIP-seq
MIRT1540735	hsa-miR-1294	CLIP-seq
MIRT1540736	hsa-miR-1976	CLIP-seq
MIRT2163267	hsa-miR-198	CLIP-seq
MIRT2163268	hsa-miR-2964a-5p	CLIP-seq
MIRT1540737	hsa-miR-3064-3p	CLIP-seq
MIRT2163269	hsa-miR-3921	CLIP-seq
MIRT1540741	hsa-miR-4316	CLIP-seq
MIRT2163270	hsa-miR-4320	CLIP-seq
MIRT1540742	hsa-miR-4502	CLIP-seq
MIRT2163271	hsa-miR-4653-5p	CLIP-seq
MIRT1540745	hsa-miR-4712-5p	CLIP-seq
MIRT1540746	hsa-miR-4715-3p	CLIP-seq
MIRT2163272	hsa-miR-4729	CLIP-seq
MIRT2163273	hsa-miR-4766-5p	CLIP-seq
MIRT1540747	hsa-miR-4768-5p	CLIP-seq
MIRT2163274	hsa-miR-654-3p	CLIP-seq
MIRT1540749	hsa-miR-770-5p	CLIP-seq
MIRT1540735	hsa-miR-1294	CLIP-seq
MIRT1540736	hsa-miR-1976	CLIP-seq
MIRT1540737	hsa-miR-3064-3p	CLIP-seq
MIRT1540739	hsa-miR-3545-3p	CLIP-seq
MIRT1540740	hsa-miR-3925-3p	CLIP-seq
MIRT1540741	hsa-miR-4316	CLIP-seq
MIRT2382394	hsa-miR-4452	CLIP-seq
MIRT1540745	hsa-miR-4712-5p	CLIP-seq
MIRT1540746	hsa-miR-4715-3p	CLIP-seq
MIRT1540747	hsa-miR-4768-5p	CLIP-seq
MIRT2382395	hsa-miR-4776-3p	CLIP-seq
MIRT2382396	hsa-miR-486-5p	CLIP-seq
MIRT1540748	hsa-miR-766	CLIP-seq
MIRT1540749	hsa-miR-770-5p	CLIP-seq
MIRT2163266	hsa-miR-1246	CLIP-seq
MIRT2163267	hsa-miR-198	CLIP-seq
MIRT2163270	hsa-miR-4320	CLIP-seq
MIRT1540743	hsa-miR-450b-5p	CLIP-seq
MIRT2673262	hsa-miR-4652-3p	CLIP-seq
MIRT1540744	hsa-miR-4696	CLIP-seq
MIRT1540745	hsa-miR-4712-5p	CLIP-seq
MIRT1540749	hsa-miR-770-5p	CLIP-seq
MIRT2163266	hsa-miR-1246	CLIP-seq
MIRT2163267	hsa-miR-198	CLIP-seq
MIRT2163269	hsa-miR-3921	CLIP-seq
MIRT2163270	hsa-miR-4320	CLIP-seq
MIRT1540743	hsa-miR-450b-5p	CLIP-seq
MIRT2673262	hsa-miR-4652-3p	CLIP-seq
MIRT2163271	hsa-miR-4653-5p	CLIP-seq
MIRT1540744	hsa-miR-4696	CLIP-seq
MIRT1540745	hsa-miR-4712-5p	CLIP-seq
MIRT1540749	hsa-miR-770-5p	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000976	Function	Transcription cis-regulatory region binding	IDA	37973953
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010468	Process	Regulation of gene expression	IEA
GO:0010558	Process	Negative regulation of macromolecule biosynthetic process	IEA
GO:0010629	Process	Negative regulation of gene expression	IDA	37973953
GO:0030154	Process	Cell differentiation	IDA	37973953
GO:0031016	Process	Pancreas development	IDA	37973953
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IEA

MIM	HGNC	e!Ensembl
620970	33230	ENSG00000198482

Q8N4W9

Protein name

Zinc finger protein 808

Protein function

Transcriptional repressor that targets mainly transposable elements (PubMed:37973953). Primarily targets the long terminal repeat of endogenous retroviruses classified as MER11 elements which comprise subfamilies A, B and C (PubMed:37973953). Ma

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	23 → 64	KRAB box	Family
PF00096	zf-C2H2	287 → 309	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	315 → 337	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	343 → 365	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	399 → 421	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	427 → 449	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	455 → 477	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	511 → 533	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	539 → 561	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	567 → 589	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	595 → 617	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	623 → 645	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	651 → 673	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	707 → 729	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	763 → 785	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	791 → 813	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	819 → 841	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	847 → 869	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	875 → 897	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: Broadly expressed. {ECO:0000269|PubMed:37973953}.

Sequence

MLREEAAQKRKGKESGMALPQGRLTFRDVAIEFSLAEWKFLNPAQRALYREVMLENYRNL
EAVDISSKHMMKEVLSTGQGNREVIHTGTLQRHQSYHIGDFCFQEIEKEIHNIEFQCQED
ERNGHEAPTTKIKKLTGSTDQHDHRHAGNKPIKDQLGSSFYSHLPELHIFQIKGEIANQL
EKSTSDASSVSTSQRISCRPQIHISNNYGNNPLNSSLLPQKQEVHMREKSFPCNESGKAF
NCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKS
SLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSR
HQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHIL
HTGEKPYKCEECDKVFSQKSTLERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGE
KTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYK
CTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEAC
DKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGKTF
SYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRS
SLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVY
HRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLSRHHRI
HTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHGIG
KFD

Sequence length

903

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Pancreatic agenesis 3	Likely pathogenic	rs2514374700	RCV004771541	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Diabetes Mellitus	Associate	37897565	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Transient Neonatal 1	Associate	37897565	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF808 (zinc finger protein 808)