Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	388389
Gene name Gene Name - the full gene name approved by the HGNC.	Dynein axonemal assembly factor 19
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DNAAF19
Synonyms (NCBI Gene) Gene synonyms aliases	CCDC103, CILD17, PR46b, SMH
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q21.31

Show/Hide all(46)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017285	hsa-miR-335-5p	Microarray	18185580
MIRT867312	hsa-miR-129-5p	CLIP-seq
MIRT867313	hsa-miR-2110	CLIP-seq
MIRT867314	hsa-miR-3126-5p	CLIP-seq
MIRT867315	hsa-miR-3147	CLIP-seq
MIRT867316	hsa-miR-3194-3p	CLIP-seq
MIRT867317	hsa-miR-3199	CLIP-seq
MIRT867318	hsa-miR-338-3p	CLIP-seq
MIRT867319	hsa-miR-4271	CLIP-seq
MIRT867320	hsa-miR-4310	CLIP-seq
MIRT867321	hsa-miR-4434	CLIP-seq
MIRT867322	hsa-miR-4515	CLIP-seq
MIRT867323	hsa-miR-4516	CLIP-seq
MIRT867324	hsa-miR-4531	CLIP-seq
MIRT867325	hsa-miR-4725-3p	CLIP-seq
MIRT867326	hsa-miR-4795-5p	CLIP-seq
MIRT867327	hsa-miR-491-5p	CLIP-seq
MIRT867328	hsa-miR-603	CLIP-seq
MIRT867329	hsa-miR-659	CLIP-seq
MIRT867330	hsa-miR-7	CLIP-seq
MIRT867313	hsa-miR-2110	CLIP-seq
MIRT867314	hsa-miR-3126-5p	CLIP-seq
MIRT1957435	hsa-miR-3136-5p	CLIP-seq
MIRT867317	hsa-miR-3199	CLIP-seq
MIRT1957436	hsa-miR-329	CLIP-seq
MIRT1957437	hsa-miR-362-3p	CLIP-seq
MIRT1957438	hsa-miR-3941	CLIP-seq
MIRT867319	hsa-miR-4271	CLIP-seq
MIRT1957439	hsa-miR-4419a	CLIP-seq
MIRT867321	hsa-miR-4434	CLIP-seq
MIRT1957440	hsa-miR-4439	CLIP-seq
MIRT1957441	hsa-miR-4510	CLIP-seq
MIRT867322	hsa-miR-4515	CLIP-seq
MIRT867323	hsa-miR-4516	CLIP-seq
MIRT867324	hsa-miR-4531	CLIP-seq
MIRT867325	hsa-miR-4725-3p	CLIP-seq
MIRT867326	hsa-miR-4795-5p	CLIP-seq
MIRT1957442	hsa-miR-490-5p	CLIP-seq
MIRT867327	hsa-miR-491-5p	CLIP-seq
MIRT867328	hsa-miR-603	CLIP-seq
MIRT867330	hsa-miR-7	CLIP-seq
MIRT1957443	hsa-miR-943	CLIP-seq
MIRT2194426	hsa-miR-1270	CLIP-seq
MIRT2194427	hsa-miR-4302	CLIP-seq
MIRT2194428	hsa-miR-4683	CLIP-seq
MIRT2194429	hsa-miR-620	CLIP-seq

Show/Hide all(22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001947	Process	Heart looping	IMP	22581229
GO:0003341	Process	Cilium movement	IGI	22581229
GO:0003351	Process	Epithelial cilium movement involved in extracellular fluid movement	IBA
GO:0005515	Function	Protein binding	IPI	25416956, 29892012, 31515488, 32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS	22581229
GO:0005929	Component	Cilium	IEA
GO:0005930	Component	Axoneme	ISS	22581229
GO:0007368	Process	Determination of left/right symmetry	IBA
GO:0030030	Process	Cell projection organization	IEA
GO:0031514	Component	Motile cilium	IEA
GO:0036157	Component	Outer dynein arm	IEA
GO:0036158	Process	Outer dynein arm assembly	IGI	22581229
GO:0036159	Process	Inner dynein arm assembly	IBA
GO:0036159	Process	Inner dynein arm assembly	IGI	22581229
GO:0042803	Function	Protein homodimerization activity	IDA	22581229
GO:0042995	Component	Cell projection	IEA
GO:0060287	Process	Epithelial cilium movement involved in determination of left/right asymmetry	IC	22581229
GO:0070286	Process	Axonemal dynein complex assembly	IEA
GO:0070286	Process	Axonemal dynein complex assembly	IMP	22581229
GO:0071907	Process	Determination of digestive tract left/right asymmetry	IMP	22581229

MIM	HGNC	e!Ensembl
614677	32700	ENSG00000167131

Protein

UniProt ID

Q8IW40

Protein name

Dynein axonemal assembly factor 19 (Coiled-coil domain-containing protein 103)

Protein function

Dynein-attachment factor required for cilia motility.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15867	Dynein_attach_N	7 → 74	Dynein attachment factor N-terminus	Family
PF13877	RPAP3_C	98 → 188	Potential Monad-binding region of RPAP3	Domain

Sequence

MERNDIINFKALEKELQAALTADEKYKRENAAKLRAVEQRVASYEEFRGIVLASHLKPLE
RKDKMGGKRTVPWNCHTIQGRTFQDVATEISPEKAPLQPETSADFYRDWRRHLPSGPERY
QALLQLGGPRLGCLFQTDVGFGLLGELLVALADHVGPADRAAVLGILCSLASTGRFTLNL
SLLSRAERESCKGLFQKLQAMGNPRSVKEGLSWEEQGLEEQSGGLQEEERLLQELLELYQ
VD

Sequence length

242

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Ciliary dyskinesia	primary ciliary dyskinesia, Primary ciliary dyskinesia 17	rs1597843267, rs2051550027, rs587776910, rs145457535, rs1060503433, rs746242380	N/A

DNAAF19 (dynein axonemal assembly factor 19)