Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	3882
Gene name	Keratin 32
Gene symbol	KRT32
Synonyms (NCBI Gene)	HA2HKA2KRTHA2hHa2
Chromosome	17
Chromosome location	17q21.2
Summary	The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019160	hsa-miR-335-5p	Microarray	18185580
MIRT030276	hsa-miR-26b-5p	Microarray	19088304
MIRT650718	hsa-miR-944	HITS-CLIP	23824327
MIRT650716	hsa-miR-1470	HITS-CLIP	23824327
MIRT650717	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT650714	hsa-miR-5193	HITS-CLIP	23824327
MIRT650715	hsa-miR-3183	HITS-CLIP	23824327
MIRT650713	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT650712	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT650711	hsa-miR-4469	HITS-CLIP	23824327
MIRT650710	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT650709	hsa-miR-4287	HITS-CLIP	23824327
MIRT650708	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT650707	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT650706	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT650705	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT650704	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT650718	hsa-miR-944	HITS-CLIP	23824327
MIRT650716	hsa-miR-1470	HITS-CLIP	23824327
MIRT650717	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT650714	hsa-miR-5193	HITS-CLIP	23824327
MIRT650715	hsa-miR-3183	HITS-CLIP	23824327
MIRT650713	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT650712	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT650711	hsa-miR-4469	HITS-CLIP	23824327
MIRT650710	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT650709	hsa-miR-4287	HITS-CLIP	23824327
MIRT650708	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT650707	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT650706	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT650705	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT650704	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT2027572	hsa-miR-1911	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0002009	Process	Morphogenesis of an epithelium	IBA
GO:0005198	Function	Structural molecule activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 36217029
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IBA
GO:0005882	Component	Intermediate filament	IEA
GO:0008544	Process	Epidermis development	TAS	7556444
GO:0030280	Function	Structural constituent of skin epidermis	IBA
GO:0030855	Process	Epithelial cell differentiation	IBA
GO:0045095	Component	Keratin filament	IBA
GO:0045109	Process	Intermediate filament organization	IBA
GO:0070062	Component	Extracellular exosome	HDA	23533145

MIM	HGNC	e!Ensembl
602760	6449	ENSG00000108759

Q14532

Protein name

Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2) (Keratin-32) (K32)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00038	Filament	95 → 406	Intermediate filament protein	Coiled-coil

Tissue specificity

TISSUE SPECIFICITY: Restricted to the hair cuticle.

Sequence

MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPAS
CLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQE
NAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADD
FRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGS
LRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVAT
SSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITN
VEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTC
VPSPCVPRTVCVPRTVGMPCSPCPQGRY

Sequence length

448

Interactions

View interactions

	KEGG		Reactome
	Estrogen signaling pathway Staphylococcus aureus infection		Keratinization Formation of the cornified envelope

KRT32 (keratin 32)