Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
388
Gene name Gene Name - the full gene name approved by the HGNC.
Ras homolog family member B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RHOB
Synonyms (NCBI Gene) Gene synonyms aliases
ARH6, ARHB, MST081, MSTP081, RHOH6
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p24.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001109 hsa-miR-223-3p Luciferase reporter assay, Western blot 19850724
MIRT001109 hsa-miR-223-3p Luciferase reporter assay 19850724
MIRT003317 hsa-miR-21-5p Luciferase reporter assay, qRT-PCR, Western blot 20460403
MIRT003317 hsa-miR-21-5p Luciferase reporter assay, qRT-PCR, Western blot 20460403
MIRT003317 hsa-miR-21-5p Luciferase reporter assay, qRT-PCR, Western blot 20460403
Transcription factors
Transcription factor Regulation Reference
HDAC1 Repression 13679859
JUN Activation 21565167
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000281 Process Mitotic cytokinesis IMP 16236794
GO:0001525 Process Angiogenesis IEA
GO:0003924 Function GTPase activity IBA 21873635
GO:0003924 Function GTPase activity TAS 3888408
GO:0005515 Function Protein binding IPI 19637314, 25249323, 27807006
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
165370 668 ENSG00000143878
Protein
UniProt ID P62745
Protein name Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Protein function Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor fo
PDB 2FV8 , 6HXU , 6SGE
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 7 180 Ras family Domain
Sequence
Sequence length 196
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Salmonella infection   GPVI-mediated activation cascade
Rho GTPase cycle
G alpha (12/13) signalling events
Sema4D induced cell migration and growth-cone collapse
RHO GTPases activate PKNs
RHO GTPases activate CIT
RHO GTPases Activate ROCKs
RHO GTPases Activate Formins