Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	387694
Gene name Gene Name - the full gene name approved by the HGNC.	SH2 domain containing 4B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SH2D4B
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q23.1

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miRTarBase ID	miRNA	Experiments
MIRT1344301	hsa-miR-1245b-3p	CLIP-seq
MIRT1344302	hsa-miR-1283	CLIP-seq
MIRT1344303	hsa-miR-1286	CLIP-seq
MIRT1344304	hsa-miR-4436a	CLIP-seq
MIRT1344305	hsa-miR-4712-3p	CLIP-seq
MIRT1344306	hsa-miR-4722-5p	CLIP-seq
MIRT1344307	hsa-miR-548aa	CLIP-seq
MIRT1344308	hsa-miR-548ag	CLIP-seq
MIRT1344309	hsa-miR-548ai	CLIP-seq
MIRT1344310	hsa-miR-548m	CLIP-seq
MIRT1344311	hsa-miR-549	CLIP-seq
MIRT1344312	hsa-miR-624	CLIP-seq
MIRT1344313	hsa-miR-185	CLIP-seq
MIRT1344314	hsa-miR-2278	CLIP-seq
MIRT1344315	hsa-miR-3148	CLIP-seq
MIRT1344316	hsa-miR-3169	CLIP-seq
MIRT1344317	hsa-miR-3173-3p	CLIP-seq
MIRT1344318	hsa-miR-3185	CLIP-seq
MIRT1344319	hsa-miR-342-3p	CLIP-seq
MIRT1344320	hsa-miR-3714	CLIP-seq
MIRT1344321	hsa-miR-4278	CLIP-seq
MIRT1344322	hsa-miR-4306	CLIP-seq
MIRT1344323	hsa-miR-4459	CLIP-seq
MIRT1344324	hsa-miR-4644	CLIP-seq
MIRT1344325	hsa-miR-4700-3p	CLIP-seq
MIRT1344326	hsa-miR-4708-3p	CLIP-seq
MIRT1344327	hsa-miR-4768-3p	CLIP-seq
MIRT1344328	hsa-miR-5095	CLIP-seq
MIRT1344329	hsa-miR-542-3p	CLIP-seq
MIRT1344330	hsa-miR-600	CLIP-seq
MIRT1344331	hsa-miR-665	CLIP-seq
MIRT2101785	hsa-miR-142-3p	CLIP-seq
MIRT2101786	hsa-miR-197	CLIP-seq
MIRT2101787	hsa-miR-3174	CLIP-seq
MIRT2101788	hsa-miR-491-3p	CLIP-seq
MIRT2101789	hsa-miR-586	CLIP-seq
MIRT2101790	hsa-miR-921	CLIP-seq
MIRT2326196	hsa-miR-224	CLIP-seq
MIRT2326197	hsa-miR-4520a-3p	CLIP-seq
MIRT2326198	hsa-miR-4520b-3p	CLIP-seq
MIRT2326199	hsa-miR-890	CLIP-seq
MIRT2466021	hsa-miR-2355-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IBA	21873635

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q5SQS7

Protein name

SH2 domain-containing protein 4B

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00017	SH2	325 → 400	SH2 domain	Domain

Sequence

MLQQILHDMYIDPELLAELSDVQKHILFYKMREEQLRRWKERETWEALAQDEGLRPPKTK
RASDKHIQWLLGADGEVWVWIMGEGPGDKPYEEISEELIAERARLQAQREAEELWRQKEA
EITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEERIHEEFKRKEEEERKRGEEQIRL
QEEQRAKELYWTLKQAQLHCQASEKEEREWEEQLRRSKAADEERSRRAQRARDEYRHHSL
RAIQKGTVAGLSSMFRELGQSHEQEARLYHHLPDPGLPQPLALPVRTWERPLRPVSRDVI
VRWFKEEQLPRRAGFERNTKFIAPWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTL
SYRLQKGFKHFLVDASGDFYSFLGVDPNRHATLTDLVDFHKEEIITVSGGELLQEPCGQR
DSPPDYHLLFE

Sequence length

431

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039 View all (65 more)	25778476
Cholelithiasis	Cholelithiasis	rs121918440, rs72552778, rs387906528, rs759202962, rs377160065, rs1051861187, rs757693457, rs752563752	17632509

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Colorectal Neoplasms	Associate	31488414

SH2D4B (SH2 domain containing 4B)