CENPW (centromere protein W)

Gene Gene information from NCBI Gene database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID 387103
Gene name Centromere protein W
Gene symbol CENPW
Synonyms (NCBI Gene)
C6orf173CENP-WCUG2
Chromosome 6
Chromosome location 6q22.32
miRNA miRNA information provided by mirtarbase database.
1
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
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miRTarBase ID miRNA Experiments Reference
MIRT885458 hsa-miR-498 CLIP-seq
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
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Transcription factor Regulation Reference
SP1 Unknown 20180024
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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GO ID Ontology Definition Evidence Reference
GO:0000278 Process Mitotic cell cycle IBA
GO:0000278 Process Mitotic cell cycle IEA
GO:0000278 Process Mitotic cell cycle IMP 21695110
GO:0000775 Component Chromosome, centromeric region IDA 19533040
GO:0000775 Component Chromosome, centromeric region IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
611264 21488 ENSG00000203760
Protein Protein information from UniProt database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5EE01
Protein name Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein)
Protein function Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nu
PDB 7QOO , 7R5S , 7XHN , 7XHO , 7YWX
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15510 CENP-W 1 → 88 CENP-W protein Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in ovary, liver, lung and pancreas and to a lower extent in breast and gastrointestinal tract cancers; such as those of the colon, rectum and stomach. Overexpressed in high grade breast invasive tumors. Expressed in ma
Sequence
Sequence length 88
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
  Reactome
    Deposition of new CENPA-containing nucleosomes at the centromere