Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3833
Gene name Gene Name - the full gene name approved by the HGNC.	Kinesin family member C1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KIFC1
Synonyms (NCBI Gene) Gene synonyms aliases	HSET, KNSL2
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p21.32

Show/Hide all(117)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024729	hsa-miR-215-5p	Microarray	19074876
MIRT051933	hsa-let-7b-5p	CLASH	23622248
MIRT049181	hsa-miR-92a-3p	CLASH	23622248
MIRT037124	hsa-miR-877-3p	CLASH	23622248
MIRT607373	hsa-miR-8485	HITS-CLIP	23313552
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23313552
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23313552
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23824327
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23824327
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23824327
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	24906430
MIRT607373	hsa-miR-8485	HITS-CLIP	24906430
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	24906430
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	24906430
MIRT526861	hsa-miR-6835-3p	PAR-CLIP	22012620
MIRT526860	hsa-miR-4422	PAR-CLIP	22012620
MIRT526859	hsa-miR-6871-3p	PAR-CLIP	22012620
MIRT526858	hsa-miR-6865-3p	PAR-CLIP	22012620
MIRT526857	hsa-miR-4530	PAR-CLIP	22012620
MIRT526856	hsa-miR-338-3p	PAR-CLIP	22012620
MIRT526855	hsa-miR-1224-3p	PAR-CLIP	22012620
MIRT526854	hsa-miR-6784-3p	PAR-CLIP	22012620
MIRT526853	hsa-miR-6862-3p	PAR-CLIP	22012620
MIRT526852	hsa-miR-766-3p	PAR-CLIP	22012620
MIRT526851	hsa-miR-532-3p	PAR-CLIP	22012620
MIRT526850	hsa-miR-1260a	PAR-CLIP	22012620
MIRT526849	hsa-miR-1260b	PAR-CLIP	22012620
MIRT607371	hsa-miR-135a-3p	Luciferase reporter assay, qRT-PCR, Western blot	27366092
MIRT607371	hsa-miR-135a-3p	Luciferase reporter assay, qRT-PCR, Western blot	27366092
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	27418678
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	27418678
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	27418678
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	27418678
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	27418678
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	27418678
MIRT607373	hsa-miR-8485	HITS-CLIP	23313552
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23313552
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23313552
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23824327
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23824327
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607372	hsa-miR-7845-5p	HITS-CLIP	23824327
MIRT607371	hsa-miR-135a-3p	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT607373	hsa-miR-8485	HITS-CLIP	23824327
MIRT526861	hsa-miR-6835-3p	PAR-CLIP	22012620
MIRT526860	hsa-miR-4422	PAR-CLIP	22012620
MIRT526859	hsa-miR-6871-3p	PAR-CLIP	22012620
MIRT526858	hsa-miR-6865-3p	PAR-CLIP	22012620
MIRT526857	hsa-miR-4530	PAR-CLIP	22012620
MIRT526856	hsa-miR-338-3p	PAR-CLIP	22012620
MIRT526855	hsa-miR-1224-3p	PAR-CLIP	22012620
MIRT526854	hsa-miR-6784-3p	PAR-CLIP	22012620
MIRT526853	hsa-miR-6862-3p	PAR-CLIP	22012620
MIRT526852	hsa-miR-766-3p	PAR-CLIP	22012620
MIRT526851	hsa-miR-532-3p	PAR-CLIP	22012620
MIRT526850	hsa-miR-1260a	PAR-CLIP	22012620
MIRT526849	hsa-miR-1260b	PAR-CLIP	22012620
MIRT1095148	hsa-miR-376c	CLIP-seq
MIRT1095149	hsa-miR-4782-5p	CLIP-seq
MIRT2025506	hsa-miR-1260	CLIP-seq
MIRT2025507	hsa-miR-1280	CLIP-seq
MIRT1095149	hsa-miR-4782-5p	CLIP-seq

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000070	Process	Mitotic sister chromatid segregation	NAS	8276466
GO:0003777	Function	Microtubule motor activity	IBA	21873635
GO:0003777	Function	Microtubule motor activity	NAS	8276466
GO:0005524	Function	ATP binding	NAS	8276466
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005769	Component	Early endosome	IEA
GO:0005815	Component	Microtubule organizing center	IBA	21873635
GO:0005871	Component	Kinesin complex	IBA	21873635
GO:0005874	Component	Microtubule	IBA	21873635
GO:0007018	Process	Microtubule-based movement	IBA	21873635
GO:0007080	Process	Mitotic metaphase plate congression	IMP	15843429
GO:0007283	Process	Spermatogenesis	IEA
GO:0008017	Function	Microtubule binding	IBA	21873635
GO:0016020	Component	Membrane	HDA	19946888
GO:0016887	Function	ATPase activity	IBA	21873635
GO:0051301	Process	Cell division	IEA
GO:0072686	Component	Mitotic spindle	IBA	21873635
GO:0090307	Process	Mitotic spindle assembly	IBA	21873635
GO:0090307	Process	Mitotic spindle assembly	IMP	15843429

MIM	HGNC	e!Ensembl
603763	6389	ENSG00000237649

Protein

UniProt ID

Q9BW19

Protein name

Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET)

Protein function

Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity). {ECO:00002

PDB

5WDH

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00225	Kinesin	349 → 663	Kinesin motor domain	Domain

Sequence

MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATT
KITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTS
GVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKA
LGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEE
RRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRL
HNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTL
SGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTM
EGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKG
QGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHS
VFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLG
LVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKV
NQCVIGTAQANRK

Sequence length

673

Interactions

View interactions

	KEGG		Reactome
	Motor proteins		COPI-dependent Golgi-to-ER retrograde traffic Kinesins

KIFC1 (kinesin family member C1)