Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3797
Gene name Gene Name - the full gene name approved by the HGNC.	Kinesin family member 3C
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KIF3C
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2p23.3

Show/Hide all(188)

miRTarBase ID	miRNA	Experiments	Reference
MIRT038608	hsa-miR-186-3p	CLASH	23622248
MIRT1094788	hsa-miR-1237	CLIP-seq
MIRT1094789	hsa-miR-1291	CLIP-seq
MIRT1094790	hsa-miR-1299	CLIP-seq
MIRT1094791	hsa-miR-1343	CLIP-seq
MIRT1094792	hsa-miR-146b-3p	CLIP-seq
MIRT1094793	hsa-miR-1827	CLIP-seq
MIRT1094794	hsa-miR-185	CLIP-seq
MIRT1094795	hsa-miR-223	CLIP-seq
MIRT1094796	hsa-miR-24	CLIP-seq
MIRT1094797	hsa-miR-2467-5p	CLIP-seq
MIRT1094798	hsa-miR-3074-5p	CLIP-seq
MIRT1094799	hsa-miR-3122	CLIP-seq
MIRT1094800	hsa-miR-3179	CLIP-seq
MIRT1094801	hsa-miR-3188	CLIP-seq
MIRT1094802	hsa-miR-3202	CLIP-seq
MIRT1094803	hsa-miR-320a	CLIP-seq
MIRT1094804	hsa-miR-320b	CLIP-seq
MIRT1094805	hsa-miR-320c	CLIP-seq
MIRT1094806	hsa-miR-320d	CLIP-seq
MIRT1094807	hsa-miR-328	CLIP-seq
MIRT1094808	hsa-miR-330-3p	CLIP-seq
MIRT1094809	hsa-miR-3612	CLIP-seq
MIRT1094810	hsa-miR-3616-3p	CLIP-seq
MIRT1094811	hsa-miR-3647-3p	CLIP-seq
MIRT1094812	hsa-miR-3655	CLIP-seq
MIRT1094813	hsa-miR-3660	CLIP-seq
MIRT1094814	hsa-miR-3690	CLIP-seq
MIRT1094815	hsa-miR-3913-5p	CLIP-seq
MIRT1094816	hsa-miR-3937	CLIP-seq
MIRT1094817	hsa-miR-3975	CLIP-seq
MIRT1094818	hsa-miR-4253	CLIP-seq
MIRT1094819	hsa-miR-4254	CLIP-seq
MIRT1094820	hsa-miR-4269	CLIP-seq
MIRT1094821	hsa-miR-4293	CLIP-seq
MIRT1094822	hsa-miR-4306	CLIP-seq
MIRT1094823	hsa-miR-4429	CLIP-seq
MIRT1094824	hsa-miR-4443	CLIP-seq
MIRT1094825	hsa-miR-4456	CLIP-seq
MIRT1094826	hsa-miR-4502	CLIP-seq
MIRT1094827	hsa-miR-4514	CLIP-seq
MIRT1094828	hsa-miR-4526	CLIP-seq
MIRT1094829	hsa-miR-4533	CLIP-seq
MIRT1094830	hsa-miR-4635	CLIP-seq
MIRT1094831	hsa-miR-4644	CLIP-seq
MIRT1094832	hsa-miR-4649-3p	CLIP-seq
MIRT1094833	hsa-miR-4677-3p	CLIP-seq
MIRT1094834	hsa-miR-4691-3p	CLIP-seq
MIRT1094835	hsa-miR-4692	CLIP-seq
MIRT1094836	hsa-miR-4693-3p	CLIP-seq
MIRT1094837	hsa-miR-4697-3p	CLIP-seq
MIRT1094838	hsa-miR-4716-3p	CLIP-seq
MIRT1094839	hsa-miR-4722-5p	CLIP-seq
MIRT1094840	hsa-miR-4742-5p	CLIP-seq
MIRT1094841	hsa-miR-4747-5p	CLIP-seq
MIRT1094842	hsa-miR-4761-3p	CLIP-seq
MIRT1094843	hsa-miR-4782-5p	CLIP-seq
MIRT1094844	hsa-miR-4789-3p	CLIP-seq
MIRT1094845	hsa-miR-4796-3p	CLIP-seq
MIRT1094846	hsa-miR-483-3p	CLIP-seq
MIRT1094847	hsa-miR-485-5p	CLIP-seq
MIRT1094848	hsa-miR-516b	CLIP-seq
MIRT1094849	hsa-miR-556-5p	CLIP-seq
MIRT1094850	hsa-miR-578	CLIP-seq
MIRT1094851	hsa-miR-610	CLIP-seq
MIRT1094852	hsa-miR-622	CLIP-seq
MIRT1094853	hsa-miR-650	CLIP-seq
MIRT1094854	hsa-miR-663b	CLIP-seq
MIRT1094855	hsa-miR-760	CLIP-seq
MIRT1550582	hsa-miR-1266	CLIP-seq
MIRT1550583	hsa-miR-3664-3p	CLIP-seq
MIRT1550584	hsa-miR-4518	CLIP-seq
MIRT2025451	hsa-miR-1294	CLIP-seq
MIRT2025452	hsa-miR-154	CLIP-seq
MIRT1094803	hsa-miR-320a	CLIP-seq
MIRT1094804	hsa-miR-320b	CLIP-seq
MIRT1094805	hsa-miR-320c	CLIP-seq
MIRT1094806	hsa-miR-320d	CLIP-seq
MIRT2025453	hsa-miR-3689d	CLIP-seq
MIRT2025454	hsa-miR-3914	CLIP-seq
MIRT1094820	hsa-miR-4269	CLIP-seq
MIRT2025455	hsa-miR-4311	CLIP-seq
MIRT1094823	hsa-miR-4429	CLIP-seq
MIRT1094827	hsa-miR-4514	CLIP-seq
MIRT1094835	hsa-miR-4692	CLIP-seq
MIRT1094840	hsa-miR-4742-5p	CLIP-seq
MIRT2256700	hsa-miR-194	CLIP-seq
MIRT2389872	hsa-miR-2355-3p	CLIP-seq
MIRT2389873	hsa-miR-3671	CLIP-seq
MIRT2452597	hsa-miR-1253	CLIP-seq
MIRT2025453	hsa-miR-3689d	CLIP-seq
MIRT2452598	hsa-miR-4302	CLIP-seq
MIRT2452599	hsa-miR-4426	CLIP-seq
MIRT2452600	hsa-miR-4434	CLIP-seq
MIRT2452601	hsa-miR-4516	CLIP-seq
MIRT2452602	hsa-miR-4534	CLIP-seq
MIRT2452603	hsa-miR-4647	CLIP-seq
MIRT2452604	hsa-miR-4648	CLIP-seq
MIRT2452605	hsa-miR-4654	CLIP-seq
MIRT2452606	hsa-miR-4662b	CLIP-seq
MIRT2452607	hsa-miR-4769-5p	CLIP-seq
MIRT2452608	hsa-miR-4802-5p	CLIP-seq
MIRT2558040	hsa-miR-1205	CLIP-seq
MIRT1094789	hsa-miR-1291	CLIP-seq
MIRT1094792	hsa-miR-146b-3p	CLIP-seq
MIRT2558041	hsa-miR-1909	CLIP-seq
MIRT2558042	hsa-miR-2682	CLIP-seq
MIRT2558043	hsa-miR-28-5p	CLIP-seq
MIRT2558044	hsa-miR-30a	CLIP-seq
MIRT2558045	hsa-miR-30b	CLIP-seq
MIRT2558046	hsa-miR-30c	CLIP-seq
MIRT2558047	hsa-miR-30d	CLIP-seq
MIRT2558048	hsa-miR-30e	CLIP-seq
MIRT2558049	hsa-miR-3139	CLIP-seq
MIRT2558050	hsa-miR-3156-3p	CLIP-seq
MIRT1094807	hsa-miR-328	CLIP-seq
MIRT2558051	hsa-miR-329	CLIP-seq
MIRT2558052	hsa-miR-331-3p	CLIP-seq
MIRT2558053	hsa-miR-362-3p	CLIP-seq
MIRT2558054	hsa-miR-3657	CLIP-seq
MIRT2558055	hsa-miR-3659	CLIP-seq
MIRT2025453	hsa-miR-3689d	CLIP-seq
MIRT2558056	hsa-miR-369-5p	CLIP-seq
MIRT2558057	hsa-miR-3941	CLIP-seq
MIRT2558058	hsa-miR-4270	CLIP-seq
MIRT2558059	hsa-miR-4280	CLIP-seq
MIRT2558060	hsa-miR-4301	CLIP-seq
MIRT2558061	hsa-miR-4441	CLIP-seq
MIRT1094825	hsa-miR-4456	CLIP-seq
MIRT2558062	hsa-miR-449c	CLIP-seq
MIRT1094827	hsa-miR-4514	CLIP-seq
MIRT2558063	hsa-miR-4530	CLIP-seq
MIRT1094830	hsa-miR-4635	CLIP-seq
MIRT2558064	hsa-miR-4658	CLIP-seq
MIRT2558065	hsa-miR-4690-5p	CLIP-seq
MIRT1094834	hsa-miR-4691-3p	CLIP-seq
MIRT1094835	hsa-miR-4692	CLIP-seq
MIRT1094839	hsa-miR-4722-5p	CLIP-seq
MIRT2558066	hsa-miR-4731-3p	CLIP-seq
MIRT2558067	hsa-miR-4732-5p	CLIP-seq
MIRT1094844	hsa-miR-4789-3p	CLIP-seq
MIRT2558068	hsa-miR-4801	CLIP-seq
MIRT1094846	hsa-miR-483-3p	CLIP-seq
MIRT2558069	hsa-miR-532-3p	CLIP-seq
MIRT2558070	hsa-miR-539	CLIP-seq
MIRT2558071	hsa-miR-574-5p	CLIP-seq
MIRT2558072	hsa-miR-600	CLIP-seq
MIRT2558073	hsa-miR-601	CLIP-seq
MIRT2558074	hsa-miR-603	CLIP-seq
MIRT2558075	hsa-miR-645	CLIP-seq
MIRT1094854	hsa-miR-663b	CLIP-seq
MIRT2558076	hsa-miR-708	CLIP-seq
MIRT2558077	hsa-miR-887	CLIP-seq
MIRT2558078	hsa-miR-922	CLIP-seq
MIRT2558079	hsa-miR-940	CLIP-seq
MIRT1094789	hsa-miR-1291	CLIP-seq
MIRT1094792	hsa-miR-146b-3p	CLIP-seq
MIRT2558044	hsa-miR-30a	CLIP-seq
MIRT2558045	hsa-miR-30b	CLIP-seq
MIRT2558046	hsa-miR-30c	CLIP-seq
MIRT2558047	hsa-miR-30d	CLIP-seq
MIRT2558048	hsa-miR-30e	CLIP-seq
MIRT1094807	hsa-miR-328	CLIP-seq
MIRT2558051	hsa-miR-329	CLIP-seq
MIRT2558052	hsa-miR-331-3p	CLIP-seq
MIRT2558053	hsa-miR-362-3p	CLIP-seq
MIRT2558054	hsa-miR-3657	CLIP-seq
MIRT2558055	hsa-miR-3659	CLIP-seq
MIRT2025453	hsa-miR-3689d	CLIP-seq
MIRT2558057	hsa-miR-3941	CLIP-seq
MIRT2558059	hsa-miR-4280	CLIP-seq
MIRT1094825	hsa-miR-4456	CLIP-seq
MIRT1094827	hsa-miR-4514	CLIP-seq
MIRT2558063	hsa-miR-4530	CLIP-seq
MIRT2558064	hsa-miR-4658	CLIP-seq
MIRT1094834	hsa-miR-4691-3p	CLIP-seq
MIRT1094835	hsa-miR-4692	CLIP-seq
MIRT2558066	hsa-miR-4731-3p	CLIP-seq
MIRT2558067	hsa-miR-4732-5p	CLIP-seq
MIRT1094844	hsa-miR-4789-3p	CLIP-seq
MIRT2558068	hsa-miR-4801	CLIP-seq
MIRT1094846	hsa-miR-483-3p	CLIP-seq
MIRT2558071	hsa-miR-574-5p	CLIP-seq
MIRT2558072	hsa-miR-600	CLIP-seq
MIRT2558074	hsa-miR-603	CLIP-seq
MIRT1094854	hsa-miR-663b	CLIP-seq
MIRT2558078	hsa-miR-922	CLIP-seq
MIRT2558079	hsa-miR-940	CLIP-seq

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003774	Function	Motor activity	TAS	9480755
GO:0003777	Function	Microtubule motor activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	17043677, 31413325, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005871	Component	Kinesin complex	IBA	21873635
GO:0005874	Component	Microtubule	IBA	21873635
GO:0005929	Component	Cilium	TAS
GO:0006890	Process	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	TAS
GO:0007018	Process	Microtubule-based movement	IBA	21873635
GO:0007018	Process	Microtubule-based movement	TAS
GO:0008017	Function	Microtubule binding	IBA	21873635
GO:0016887	Function	ATPase activity	IBA	21873635
GO:0019886	Process	Antigen processing and presentation of exogenous peptide antigen via MHC class II	TAS
GO:0035735	Process	Intraciliary transport involved in cilium assembly	TAS
GO:0072384	Process	Organelle transport along microtubule	IEA
GO:0097542	Component	Ciliary tip	TAS

MIM	HGNC	e!Ensembl
602845	6321	ENSG00000084731

Protein

UniProt ID

O14782

Protein name

Kinesin-like protein KIF3C

Protein function

Microtubule-based anterograde translocator for membranous organelles.

PDB

3B6V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00225	Kinesin	16 → 265	Kinesin motor domain	Domain
PF00225	Kinesin	276 → 365	Kinesin motor domain	Domain

Sequence

MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF
DAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI
PNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL
SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG
KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL
GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN
RAKNIKNKPQVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG
YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS
LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE
LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA
EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK
FQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPA
VFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLA
SASLRPATVADHE

Sequence length

793

Interactions

View interactions

	KEGG		Reactome
	Motor proteins		MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Amyotrophic lateral sclerosis	Amyotrophic Lateral Sclerosis, Familial	rs267607084, rs312262720, rs312262752, rs121908287, rs121908288, rs29001584, rs28941475, rs121434378, rs386134173, rs386134174, rs80356730, rs80356727, rs4884357, rs80356717, rs80356733 View all (171 more)	11796754
Atrial fibrillation	Atrial Fibrillation	rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557 View all (6 more)	29892015, 30061737
Lateral sclerosis	AMYOTROPHIC LATERAL SCLEROSIS 1, Amyotrophic Lateral Sclerosis, Sporadic	rs386134181, rs386134176, rs386134174, rs386134184, rs386134178, rs1693780539, rs1574698048	11796754

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Evidence	References	Source
Unknown
Paroxysmal atrial fibrillation	Paroxysmal atrial fibrillation		29892015, 30061737	ClinVar
Multiple myeloma	Multiple myeloma	MM cells lacking PSMC6 also developed resistance against Carfilzomib (CAR)		GWAS, CBGDA
Atrial Fibrillation	Atrial Fibrillation			GWAS
Diabetes	Diabetes			GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining
Cell Transformation Neoplastic	Associate	38552217
Colorectal Neoplasms	Associate	40075273
Esophageal Neoplasms	Associate	34057012
Glioma	Associate	33150178
Neoplasms	Associate	33150178, 38552217
Neoplasms	Stimulate	40075273
Prostatic Neoplasms	Associate	34537760
Stomach Neoplasms	Associate	38552217

KIF3C (kinesin family member 3C)