Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3782
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Potassium calcium-activated channel subfamily N member 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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KCNN3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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KCa2.3, SK3, SKCA3, ZLS3, hSK3 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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ZLS3 |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Atrial fibrillation |
Atrial Fibrillation |
rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557, rs587777558, rs587777559, rs587777560, rs886037778, rs769405762, rs770372675 View all (6 more) |
30061737, 29290336, 20173747, 22544366, 29892015, 28416818 |
Prostate cancer |
Malignant neoplasm of prostate, Prostate carcinoma |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
23535732, 29892016 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
20933057, 16393881, 12808432 |
Zimmerman laband syndrome |
Zimmerman Laband syndrome, Zimmermann-Laband syndrome |
rs727502819, rs730882175, rs730882173, rs730882176, rs730882174, rs730882172, rs730882177, rs886041300, rs1135401772, rs1571259807, rs1571353663, rs1571260285 |
31155282 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Paroxysmal atrial fibrillation |
Paroxysmal atrial fibrillation |
|
30061737, 20173747 |
ClinVar |
Zimmerman Laband Syndrome |
Zimmermann-Laband syndrome 3, Zimmermann-Laband syndrome |
|
|
GenCC |
Atrial Fibrillation |
Atrial Fibrillation |
|
|
GWAS |
Bipolar Disorder |
Bipolar Disorder |
|
|
GWAS |
Cholelithiasis |
Cholelithiasis |
|
|
GWAS |
Glioblastoma |
Glioblastoma |
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 |
|
GWAS, CBGDA |
Parkinson disease |
Parkinson disease |
|
|
GWAS |
Dyslexia |
Dyslexia |
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|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Abortion Habitual |
Associate
|
39299134 |
Atrial Fibrillation |
Associate
|
20173747, 21107608, 22019810, 22384221, 22726630, 23428961, 24910551, 26272656, 28175276, 28381281, 29624624, 31152482, 33350184 |
Atrial Fibrillation |
Stimulate
|
30664154 |
Breast Neoplasms |
Associate
|
20955368, 26619845 |
Cardiomyopathies |
Associate
|
26710323 |
Cardiomyopathy Dilated |
Associate
|
26710323 |
Channelopathies |
Associate
|
33594261, 35030515 |
Cholangiocarcinoma |
Associate
|
29408647 |
Ciliary Motility Disorders |
Associate
|
24824133 |
COVID 19 |
Associate
|
36104591 |
Dehydrated Hereditary Stomatocytosis Pseudohyperkalemia and Perinatal Edema |
Associate
|
35030515 |
Developmental Disabilities |
Associate
|
33594261 |
digital ulcers |
Associate
|
33594261 |
Genetic Diseases Inborn |
Associate
|
33594261 |
Gingivitis |
Associate
|
33594261 |
Glioma |
Associate
|
16817201 |
Hemiplegic migraine familial type 2 |
Associate
|
22030984 |
Heterotaxy Syndrome |
Associate
|
28381281 |
Hirschsprung Disease |
Associate
|
29439660 |
Hyperphagia |
Associate
|
36812308 |
Hypertrichosis |
Associate
|
33594261 |
Hypoxia |
Associate
|
32640738 |
Idiopathic Noncirrhotic Portal Hypertension |
Associate
|
35030515 |
Melanoma |
Associate
|
26619845 |
Migraine Disorders |
Associate
|
22030984 |
Mitral Valve Stenosis |
Stimulate
|
30664154 |
Myotonic Dystrophy |
Associate
|
19472917 |
Neoplasm Metastasis |
Associate
|
29408647 |
Neoplasms |
Associate
|
16817201, 20955368, 26619845 |
Nervous System Diseases |
Associate
|
24434522 |
Obesity |
Associate
|
36812308 |
Ovarian Neoplasms |
Inhibit
|
29901154 |
Primary Myelofibrosis |
Associate
|
23733509 |
Psychological Distress |
Stimulate
|
30664154 |
Sjogren's Syndrome |
Stimulate
|
39299134 |
Tachycardia Ventricular |
Associate
|
26710323 |
Urethral Neoplasms |
Associate
|
26619845 |
Urinary Bladder Neoplasms |
Associate
|
31696467 |
Ventricular Dysfunction Left |
Associate
|
26710323 |
Zimmerman Laband syndrome |
Associate
|
33594261, 35030515 |
|