KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 3779 |
| Gene name | Potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
| Gene symbol | KCNMB1 |
| Synonyms (NCBI Gene) |
BKbeta1K(VCA)betaSLO-BETAhbeta1hslo-betak(VCA)beta-1slo-beta-1
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| Chromosome | 5 |
| Chromosome location | 5q35.1 |
| Summary | MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the |
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miRNA
miRNA information provided by mirtarbase database.
356
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q16558 | ||||||||||
| Protein name | Calcium-activated potassium channel subunit beta-1 (BK channel subunit beta-1) (BKbeta) (BKbeta1) (Hbeta1) (Calcium-activated potassium channel, subfamily M subunit beta-1) (Calcium-activated potassium channel subunit beta) (Charybdotoxin receptor subunit | ||||||||||
| Protein function | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Abundantly expressed in smooth muscle. Low levels of expression in most other tissues. Within the brain, relatively high levels found in hippocampus and corpus callosum. | ||||||||||
| Sequence |
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| Sequence length | 191 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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