KCNJ6 (potassium inwardly rectifying channel subfamily J member 6)

Gene

• Entrez ID: 3763
• Gene name: Potassium inwardly rectifying channel subfamily J member 6
• Gene symbol: KCNJ6
• Synonyms (NCBI Gene): BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, KPLBS, hiGIRK2
• Disease Acronyms (UniProt): KPLBS
• Chromosome: 21
• Chromosome location: 21q22.13
• Summary: This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulat

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019353	hsa-miR-148b-3p	Microarray	17612493
MIRT021940	hsa-miR-128-3p	Microarray	17612493
MIRT712455	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT712454	hsa-miR-8088	HITS-CLIP	19536157
MIRT712453	hsa-miR-885-3p	HITS-CLIP	19536157
MIRT715622	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT715621	hsa-miR-651-3p	HITS-CLIP	19536157
MIRT715620	hsa-miR-216b-5p	HITS-CLIP	19536157
MIRT715619	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT715618	hsa-miR-3148	HITS-CLIP	19536157
MIRT715617	hsa-miR-888-3p	HITS-CLIP	19536157
MIRT715616	hsa-miR-501-3p	HITS-CLIP	19536157
MIRT715615	hsa-miR-502-3p	HITS-CLIP	19536157
MIRT715614	hsa-miR-6719-3p	HITS-CLIP	19536157
MIRT715613	hsa-miR-4725-5p	HITS-CLIP	19536157
MIRT712455	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT712454	hsa-miR-8088	HITS-CLIP	19536157
MIRT712453	hsa-miR-885-3p	HITS-CLIP	19536157
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT514068	hsa-miR-8076	HITS-CLIP	21572407
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	21572407
MIRT514065	hsa-miR-758-5p	HITS-CLIP	21572407
MIRT640078	hsa-miR-4698	HITS-CLIP	21572407
MIRT514064	hsa-miR-151a-3p	HITS-CLIP	21572407
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT514063	hsa-miR-584-5p	HITS-CLIP	21572407
MIRT514062	hsa-miR-493-5p	HITS-CLIP	21572407
MIRT514061	hsa-miR-7702	HITS-CLIP	21572407
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT514068	hsa-miR-8076	HITS-CLIP	21572407
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	21572407
MIRT514065	hsa-miR-758-5p	HITS-CLIP	21572407
MIRT640078	hsa-miR-4698	HITS-CLIP	21572407
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT514063	hsa-miR-584-5p	HITS-CLIP	21572407
MIRT514062	hsa-miR-493-5p	HITS-CLIP	21572407
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT514068	hsa-miR-8076	HITS-CLIP	23313552
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	23313552
MIRT514065	hsa-miR-758-5p	HITS-CLIP	23313552
MIRT640078	hsa-miR-4698	HITS-CLIP	23313552
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT514063	hsa-miR-584-5p	HITS-CLIP	23313552
MIRT514062	hsa-miR-493-5p	HITS-CLIP	23313552
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT667774	hsa-miR-122-3p	HITS-CLIP	23824327
MIRT657032	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT657031	hsa-miR-4532	HITS-CLIP	23824327
MIRT674018	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT674017	hsa-miR-1976	HITS-CLIP	23824327
MIRT657027	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT674016	hsa-miR-4279	HITS-CLIP	23824327
MIRT623549	hsa-miR-1470	HITS-CLIP	23824327
MIRT623548	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT623547	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT623545	hsa-miR-4469	HITS-CLIP	23824327
MIRT623544	hsa-miR-4287	HITS-CLIP	23824327
MIRT623543	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT623542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT657038	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT657037	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT657036	hsa-miR-507	HITS-CLIP	23824327
MIRT657035	hsa-miR-557	HITS-CLIP	23824327
MIRT657034	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT657042	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623538	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT667774	hsa-miR-122-3p	HITS-CLIP	23824327
MIRT657033	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT657032	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT657031	hsa-miR-4532	HITS-CLIP	23824327
MIRT657030	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT667773	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT657029	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT657028	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT657027	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT667772	hsa-miR-4284	HITS-CLIP	23824327
MIRT623537	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT623536	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT623535	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT623534	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT623533	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT623532	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT623531	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT657042	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623549	hsa-miR-1470	HITS-CLIP	23824327
MIRT623548	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT623547	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT623546	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT657041	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT623545	hsa-miR-4469	HITS-CLIP	23824327
MIRT623544	hsa-miR-4287	HITS-CLIP	23824327
MIRT623543	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT623542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT657040	hsa-miR-1273h-3p	HITS-CLIP	23824327
MIRT657039	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT657038	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT657037	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT657036	hsa-miR-507	HITS-CLIP	23824327
MIRT657035	hsa-miR-557	HITS-CLIP	23824327
MIRT657034	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT623538	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT657033	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT657032	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT657031	hsa-miR-4532	HITS-CLIP	23824327
MIRT657030	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT657029	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT657028	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT657027	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT623537	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT623536	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT623535	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT623534	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT623532	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT623531	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT514068	hsa-miR-8076	HITS-CLIP	23824327
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	23824327
MIRT514065	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT640078	hsa-miR-4698	HITS-CLIP	23824327
MIRT514064	hsa-miR-151a-3p	HITS-CLIP	23824327
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT514063	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT514062	hsa-miR-493-5p	HITS-CLIP	23824327
MIRT514061	hsa-miR-7702	HITS-CLIP	23824327
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT623549	hsa-miR-1470	HITS-CLIP	23824327
MIRT623548	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT623547	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT623546	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT623545	hsa-miR-4469	HITS-CLIP	23824327
MIRT623544	hsa-miR-4287	HITS-CLIP	23824327
MIRT623543	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT623542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT623539	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT623538	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT514068	hsa-miR-8076	HITS-CLIP	23824327
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	23824327
MIRT514065	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT514064	hsa-miR-151a-3p	HITS-CLIP	23824327
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT514063	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT623537	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT623536	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT623535	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT623534	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT623533	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT623532	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT623531	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT568661	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT572276	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT572275	hsa-miR-567	PAR-CLIP	20371350
MIRT572274	hsa-miR-297	PAR-CLIP	20371350
MIRT572273	hsa-miR-210-3p	PAR-CLIP	20371350
MIRT568661	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT568660	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT503235	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT503233	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT514068	hsa-miR-8076	PAR-CLIP	21572407
MIRT514066	hsa-miR-218-2-3p	PAR-CLIP	21572407
MIRT514065	hsa-miR-758-5p	PAR-CLIP	21572407
MIRT514064	hsa-miR-151a-3p	PAR-CLIP	21572407
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT514063	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT514061	hsa-miR-7702	PAR-CLIP	21572407
MIRT514067	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT514068	hsa-miR-8076	PAR-CLIP	23446348
MIRT514066	hsa-miR-218-2-3p	PAR-CLIP	23446348
MIRT514065	hsa-miR-758-5p	PAR-CLIP	23446348
MIRT514064	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT514063	hsa-miR-584-5p	PAR-CLIP	23446348
MIRT514062	hsa-miR-493-5p	PAR-CLIP	23446348
MIRT514061	hsa-miR-7702	PAR-CLIP	23446348
MIRT503235	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503233	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT495449	hsa-miR-3910	PAR-CLIP	22291592
MIRT495448	hsa-miR-3690	PAR-CLIP	22291592
MIRT495447	hsa-miR-645	PAR-CLIP	22291592
MIRT495446	hsa-miR-378a-3p	PAR-CLIP	22291592
MIRT495445	hsa-miR-378b	PAR-CLIP	22291592
MIRT495444	hsa-miR-378c	PAR-CLIP	22291592
MIRT495443	hsa-miR-378d	PAR-CLIP	22291592
MIRT495442	hsa-miR-378e	PAR-CLIP	22291592
MIRT495441	hsa-miR-378f	PAR-CLIP	22291592
MIRT495440	hsa-miR-378h	PAR-CLIP	22291592
MIRT495439	hsa-miR-378i	PAR-CLIP	22291592
MIRT495438	hsa-miR-422a	PAR-CLIP	22291592
MIRT495437	hsa-miR-1254	PAR-CLIP	22291592
MIRT495436	hsa-miR-3116	PAR-CLIP	22291592
MIRT495435	hsa-miR-6503-3p	PAR-CLIP	22291592
MIRT495434	hsa-miR-3157-5p	PAR-CLIP	22291592
MIRT712455	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT712454	hsa-miR-8088	HITS-CLIP	19536157
MIRT712453	hsa-miR-885-3p	HITS-CLIP	19536157
MIRT715622	hsa-miR-548c-3p	HITS-CLIP	19536157
MIRT715621	hsa-miR-651-3p	HITS-CLIP	19536157
MIRT715620	hsa-miR-216b-5p	HITS-CLIP	19536157
MIRT715619	hsa-miR-3675-3p	HITS-CLIP	19536157
MIRT715618	hsa-miR-3148	HITS-CLIP	19536157
MIRT715617	hsa-miR-888-3p	HITS-CLIP	19536157
MIRT715616	hsa-miR-501-3p	HITS-CLIP	19536157
MIRT715615	hsa-miR-502-3p	HITS-CLIP	19536157
MIRT715614	hsa-miR-6719-3p	HITS-CLIP	19536157
MIRT715613	hsa-miR-4725-5p	HITS-CLIP	19536157
MIRT712455	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT712454	hsa-miR-8088	HITS-CLIP	19536157
MIRT712453	hsa-miR-885-3p	HITS-CLIP	19536157
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT514068	hsa-miR-8076	HITS-CLIP	21572407
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	21572407
MIRT514065	hsa-miR-758-5p	HITS-CLIP	21572407
MIRT640078	hsa-miR-4698	HITS-CLIP	21572407
MIRT514064	hsa-miR-151a-3p	HITS-CLIP	21572407
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT514063	hsa-miR-584-5p	HITS-CLIP	21572407
MIRT514062	hsa-miR-493-5p	HITS-CLIP	21572407
MIRT514061	hsa-miR-7702	HITS-CLIP	21572407
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT514068	hsa-miR-8076	HITS-CLIP	21572407
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	21572407
MIRT514065	hsa-miR-758-5p	HITS-CLIP	21572407
MIRT640078	hsa-miR-4698	HITS-CLIP	21572407
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT514063	hsa-miR-584-5p	HITS-CLIP	21572407
MIRT514062	hsa-miR-493-5p	HITS-CLIP	21572407
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT514068	hsa-miR-8076	HITS-CLIP	23313552
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	23313552
MIRT514065	hsa-miR-758-5p	HITS-CLIP	23313552
MIRT640078	hsa-miR-4698	HITS-CLIP	23313552
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT514063	hsa-miR-584-5p	HITS-CLIP	23313552
MIRT514062	hsa-miR-493-5p	HITS-CLIP	23313552
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT667774	hsa-miR-122-3p	HITS-CLIP	23824327
MIRT657032	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT657031	hsa-miR-4532	HITS-CLIP	23824327
MIRT674018	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT674017	hsa-miR-1976	HITS-CLIP	23824327
MIRT657027	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT674016	hsa-miR-4279	HITS-CLIP	23824327
MIRT623549	hsa-miR-1470	HITS-CLIP	23824327
MIRT623548	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT623547	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT623545	hsa-miR-4469	HITS-CLIP	23824327
MIRT623544	hsa-miR-4287	HITS-CLIP	23824327
MIRT623543	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT623542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT657038	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT657037	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT657036	hsa-miR-507	HITS-CLIP	23824327
MIRT657035	hsa-miR-557	HITS-CLIP	23824327
MIRT657034	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT657042	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623538	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT667774	hsa-miR-122-3p	HITS-CLIP	23824327
MIRT657033	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT657032	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT657031	hsa-miR-4532	HITS-CLIP	23824327
MIRT657030	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT667773	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT657029	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT657028	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT657027	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT667772	hsa-miR-4284	HITS-CLIP	23824327
MIRT623537	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT623536	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT623535	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT623534	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT623533	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT623532	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT623531	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT657042	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT623549	hsa-miR-1470	HITS-CLIP	23824327
MIRT623548	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT623547	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT623546	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT657041	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT623545	hsa-miR-4469	HITS-CLIP	23824327
MIRT623544	hsa-miR-4287	HITS-CLIP	23824327
MIRT623543	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT623542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT657040	hsa-miR-1273h-3p	HITS-CLIP	23824327
MIRT657039	hsa-miR-3678-3p	HITS-CLIP	23824327
MIRT657038	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT657037	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT657036	hsa-miR-507	HITS-CLIP	23824327
MIRT657035	hsa-miR-557	HITS-CLIP	23824327
MIRT657034	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT623538	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT657033	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT657032	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT657031	hsa-miR-4532	HITS-CLIP	23824327
MIRT657030	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT657029	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT657028	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT657027	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT623537	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT623536	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT623535	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT623534	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT623532	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT623531	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT514067	hsa-miR-5580-3p	HITS-CLIP	23824327
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT514068	hsa-miR-8076	HITS-CLIP	23824327
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	23824327
MIRT514065	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT640078	hsa-miR-4698	HITS-CLIP	23824327
MIRT514064	hsa-miR-151a-3p	HITS-CLIP	23824327
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT514063	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT514062	hsa-miR-493-5p	HITS-CLIP	23824327
MIRT514061	hsa-miR-7702	HITS-CLIP	23824327
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT623549	hsa-miR-1470	HITS-CLIP	23824327
MIRT623548	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT623547	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT623546	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT623545	hsa-miR-4469	HITS-CLIP	23824327
MIRT623544	hsa-miR-4287	HITS-CLIP	23824327
MIRT623543	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT623542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT623541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT623540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT623539	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT623538	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT503235	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT514068	hsa-miR-8076	HITS-CLIP	23824327
MIRT514066	hsa-miR-218-2-3p	HITS-CLIP	23824327
MIRT514065	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT514064	hsa-miR-151a-3p	HITS-CLIP	23824327
MIRT503234	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT514063	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT503233	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT623537	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT623536	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT623535	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT623534	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT623533	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT623532	hsa-miR-5004-3p	HITS-CLIP	23824327
MIRT623531	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT568661	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT572276	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT572275	hsa-miR-567	PAR-CLIP	20371350
MIRT572274	hsa-miR-297	PAR-CLIP	20371350
MIRT572273	hsa-miR-210-3p	PAR-CLIP	20371350
MIRT568661	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT568660	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT503235	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT503233	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT514068	hsa-miR-8076	PAR-CLIP	21572407
MIRT514066	hsa-miR-218-2-3p	PAR-CLIP	21572407
MIRT514065	hsa-miR-758-5p	PAR-CLIP	21572407
MIRT514064	hsa-miR-151a-3p	PAR-CLIP	21572407
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT514063	hsa-miR-584-5p	PAR-CLIP	21572407
MIRT514061	hsa-miR-7702	PAR-CLIP	21572407
MIRT514067	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT514068	hsa-miR-8076	PAR-CLIP	23446348
MIRT514066	hsa-miR-218-2-3p	PAR-CLIP	23446348
MIRT514065	hsa-miR-758-5p	PAR-CLIP	23446348
MIRT514064	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT514063	hsa-miR-584-5p	PAR-CLIP	23446348
MIRT514062	hsa-miR-493-5p	PAR-CLIP	23446348
MIRT514061	hsa-miR-7702	PAR-CLIP	23446348
MIRT503235	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT503234	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503233	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT495449	hsa-miR-3910	PAR-CLIP	22291592
MIRT495448	hsa-miR-3690	PAR-CLIP	22291592
MIRT495447	hsa-miR-645	PAR-CLIP	22291592
MIRT495446	hsa-miR-378a-3p	PAR-CLIP	22291592
MIRT495445	hsa-miR-378b	PAR-CLIP	22291592
MIRT495444	hsa-miR-378c	PAR-CLIP	22291592
MIRT495443	hsa-miR-378d	PAR-CLIP	22291592
MIRT495442	hsa-miR-378e	PAR-CLIP	22291592
MIRT495441	hsa-miR-378f	PAR-CLIP	22291592
MIRT495440	hsa-miR-378h	PAR-CLIP	22291592
MIRT495439	hsa-miR-378i	PAR-CLIP	22291592
MIRT495438	hsa-miR-422a	PAR-CLIP	22291592
MIRT495437	hsa-miR-1254	PAR-CLIP	22291592
MIRT495436	hsa-miR-3116	PAR-CLIP	22291592
MIRT495435	hsa-miR-6503-3p	PAR-CLIP	22291592
MIRT495434	hsa-miR-3157-5p	PAR-CLIP	22291592
MIRT1081581	hsa-miR-140-5p	CLIP-seq
MIRT1081582	hsa-miR-203	CLIP-seq
MIRT1081583	hsa-miR-219-2-3p	CLIP-seq
MIRT1081584	hsa-miR-2964a-3p	CLIP-seq
MIRT1081585	hsa-miR-3616-3p	CLIP-seq
MIRT1081586	hsa-miR-3646	CLIP-seq
MIRT1081587	hsa-miR-3665	CLIP-seq
MIRT1081588	hsa-miR-411	CLIP-seq
MIRT1081589	hsa-miR-4325	CLIP-seq
MIRT1081590	hsa-miR-4643	CLIP-seq
MIRT1081591	hsa-miR-4721	CLIP-seq
MIRT1081592	hsa-miR-511	CLIP-seq
MIRT1081593	hsa-miR-657	CLIP-seq
MIRT2252040	hsa-miR-101	CLIP-seq
MIRT2252041	hsa-miR-144	CLIP-seq
MIRT2465516	hsa-miR-451b	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005242	Function	Inward rectifier potassium channel activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	12297500, 32296183
GO:0005794	Component	Golgi apparatus	HDA	16780588
GO:0005886	Component	Plasma membrane	HDA	16780588
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0005886	Component	Plasma membrane	TAS
GO:0006813	Process	Potassium ion transport	TAS	7796919
GO:0008076	Component	Voltage-gated potassium channel complex	TAS	7796919
GO:0015467	Function	G-protein activated inward rectifier potassium channel activity	IEA
GO:0034765	Process	Regulation of ion transmembrane transport	IBA	21873635
GO:1990573	Process	Potassium ion import across plasma membrane	IBA	21873635

Other IDs

• MIM: 600877
• HGNC: 6267
• e!Ensembl: ENSG00000157542

Protein

• UniProt ID: P48051
• Protein name: G protein-activated inward rectifier potassium channel 2 (GIRK-2) (BIR1) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (Potassium channel, inwardly rectifying subfamily J member 6)
• Protein function: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potass
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01007	IRK	57 → 196	Inward rectifier potassium channel transmembrane domain	Domain
  PF17655	IRK_C	203 → 375	Inward rectifier potassium channel C-terminal domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas. {ECO:0000269|PubMed:7592809}.
• Sequence:

  MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKD
  GKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGD
  MDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSI
  VNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAK
  LIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKE
  ELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYET
  STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENE
  SKV

• Sequence length: 423

Pathways

KEGG:

Circadian entrainment
Retrograde endocannabinoid signaling
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Estrogen signaling pathway
Oxytocin signaling pathway
GnRH secretion
Morphine addiction

Reactome:

Activation of G protein gated Potassium channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Mental retardation	Severe intellectual disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315, rs121918316, rs397515320, rs121434489, rs1585215916, rs267607233, rs267606752, rs137852214, rs606231193, rs132630297, rs80338758, rs137852815, rs122455132, rs28935171, rs122453113, rs122445108, rs28934904, rs28934908, rs28935468, rs61748421, rs121918624, rs202060209, rs80338708, rs113994198, rs199422192, rs387906635, rs1554770064, rs1057519611, rs1060499526, rs387906636, rs1057519612, rs281875189, rs281875322, rs387906799, rs387906804, rs875989800, rs797045262, rs387906845, rs387906846, rs876657378, rs281875227, rs281875228, rs281875229, rs281875230, rs387906861, rs370667926, rs387906932, rs387906943, rs1557612719, rs387907190, rs387907191, rs2126499522, rs587776908, rs1560982564, rs80359505, rs398123009, rs587776929, rs587776930, rs397514555, rs398122824, rs398122825, rs397514556, rs2147483647, rs587776937, rs397514627, rs397514655, rs397514656, rs730882192, rs1587520018, rs1581995953, rs1554121970, rs1581987445, rs397514670, rs376395543, rs137854128, rs397509411, rs397509412, rs397514741, rs398122394, rs879255516, rs397518483, rs398122406, rs398122412, rs398123561, rs200667343, rs587777162, rs587777202, rs62507350, rs587777219, rs587777225, rs587777226, rs587779750, rs587777326, rs587777334, rs281875332, rs587780470, rs587780474, rs587780486, rs587777378, rs587777406, rs587777408, rs587777409, rs587777411, rs587777522, rs527236034, rs527236035, rs267608571, rs267608382, rs267608597, rs61753979, rs61751444, rs267608493, rs587777644, rs587777645, rs587777646, rs587777703, rs587779388, rs606231266, rs606231267, rs672601340, rs606231268, rs672601341, rs606231269, rs672601342, rs606231270, rs606231271, rs606231272, rs606231273, rs587784566, rs587784092, rs587783749, rs587783747, rs587783640, rs587783483, rs606231456, rs606231457, rs606231458, rs606231459, rs672601370, rs672601369, rs672601371, rs672601367, rs672601366, rs672601365, rs672601364, rs672601363, rs672601362, rs672601376, rs672601377, rs672601378, rs724159949, rs724159950, rs724159948, rs724159956, rs724159953, rs727502860, rs727502861, rs730882197, rs749995448, rs786205143, rs794726770, rs1135401808, rs786205583, rs786205595, rs786205859, rs794727792, rs794727928, rs794729221, rs797044519, rs797044523, rs797044521, rs797044524, rs797044526, rs797044522, rs797044520, rs794727642, rs796052719, rs781746113, rs796052510, rs796052733, rs796052724, rs796052728, rs796052676, rs796053353, rs796053366, rs796053368, rs1555103986, rs1555110818, rs796052571, rs1555110843, rs796052626, rs796052618, rs796053290, rs796052217, rs672601368, rs797045164, rs797044961, rs797044962, rs200070245, rs797044963, rs869320675, rs869320676, rs797045012, rs752746786, rs797044885, rs797044925, rs797044854, rs797044849, rs797044930, rs797044901, rs797044918, rs797044884, rs797045177, rs797045178, rs797045050, rs797045036, rs797045053, rs797045047, rs797045037, rs797045042, rs797045041, rs879255261, rs782397980, rs797045263, rs797045264, rs797045655, rs797045586, rs545185248, rs797046031, rs797046028, rs797046029, rs797046030, rs797045249, rs797045529, rs797045952, rs797045984, rs797045540, rs797045539, rs797045989, rs863224930, rs869025202, rs863225264, rs863225077, rs876661308, rs869025222, rs864309560, rs758252808, rs745756308, rs869025286, rs869025287, rs869025578, rs143038880, rs869025579, rs869025580, rs869025581, rs869312704, rs869312674, rs869312677, rs869312689, rs869312693, rs869312698, rs869312708, rs869312711, rs869312826, rs869312825, rs869312824, rs869312823, rs758432471, rs869312821, rs761993070, rs869312844, rs869312842, rs869312843, rs869312841, rs869312847, rs869320632, rs869312955, rs773432002, rs869320713, rs869320772, rs869320773, rs879255270, rs875989848, rs875989849, rs1716457622, rs2108414289, rs878854401, rs875989786, rs1085307109, rs1085307108, rs876657679, rs876661167, rs876661076, rs876661055, rs876661219, rs876661064, rs876661151, rs876661041, rs200440467, rs876661295, rs878853045, rs878853143, rs878853142, rs878853149, rs1555910048, rs878853152, rs878853146, rs878853145, rs878853141, rs878853151, rs878853144, rs878853148, rs878853147, rs878853251, rs878853269, rs879253762, rs886037841, rs879253888, rs879253931, rs879254016, rs879255618, rs879255619, rs879255620, rs886037847, rs879255621, rs886039332, rs746177928, rs886039520, rs886041003, rs886041058, rs750035706, rs886041059, rs886041060, rs886041061, rs886041090, rs886041088, rs886041089, rs886041095, rs886041097, rs886041989, rs886041944, rs886041692, rs886041593, rs886041687, rs886041207, rs886041309, rs886041239, rs886041448, rs138336847, rs149644940, rs886041295, rs886041521, rs886041125, rs886042041, rs886041238, rs886041469, rs886041197, rs886041291, rs886041658, rs886041705, rs886041876, rs139716296, rs1057516030, rs1057517408, rs749655461, rs141179774, rs370916968, rs1057517676, rs1057517933, rs1057517708, rs1057518352, rs1057518183, rs1057518474, rs1057518204, rs1057517825, rs1057518796, rs1057518961, rs1057518772, rs1057518988, rs1057519004, rs1057518700, rs772450541, rs371310428, rs1057519019, rs1057519491, rs1057519546, rs1057519560, rs1057519565, rs1057519400, rs1057519402, rs1057519405, rs1057519593, rs1057519594, rs1057519628, rs1556912828, rs1060505029, rs1060505030, rs147001633, rs1057519947, rs1057519617, rs1057524832, rs774592932, rs797045045, rs1039571136, rs1555910821, rs1060499626, rs1060499655, rs1554770185, rs1060499936, rs1060501153, rs1060501151, rs1064792984, rs1060503378, rs1060503386, rs1060503383, rs1060500046, rs1064792999, rs1060505033, rs1064796564, rs1064797002, rs1064793161, rs150802299, rs1064796830, rs1064794996, rs1064795444, rs1064796034, rs1064796403, rs1064794979, rs1064796765, rs1064793539, rs760933323, rs1064793546, rs1064796406, rs1064796367, rs780441716, rs1064794894, rs1064796023, rs1064797355, rs1085307484, rs1064794935, rs1085307547, rs1131690804, rs757511770, rs1131691875, rs1131691979, rs398122823, rs1131691866, rs1131692159, rs1131692228, rs1131692154, rs113331868, rs1554121872, rs1554121875, rs926027867, rs1554122123, rs1554122129, rs1287121256, rs1554122526, rs1554123982, rs1554385102, rs1554385111, rs1554385305, rs1554386687, rs1554389088, rs1554402092, rs1554434435, rs1135401778, rs1135401760, rs1135401770, rs1135401771, rs1135401768, rs1135401779, rs1135401805, rs1135401797, rs1135401799, rs1135401816, rs1135401823, rs1135401824, rs1555769968, rs1135401825, rs1135401955, rs1135401956, rs1135401957, rs1135401958, rs1554129040, rs1554150543, rs1553188463, rs1553146165, rs1485978447, rs1361547443, rs750079325, rs369692236, rs1554231836, rs749188610, rs1554122735, rs1554689877, rs1174482090, rs781053477, rs1554623112, rs1555409836, rs1555411305, rs770014321, rs1555984461, rs1555990958, rs762292772, rs1554944271, rs1057524157, rs1485749468, rs1555984343, rs1293450628, rs373584239, rs1553722309, rs1553738686, rs1376334317, rs1553722294, rs1553283831, rs1554120589, rs1555985554, rs1555877287, rs1555411378, rs750922282, rs1553264873, rs1554263326, rs1554264268, rs1554263626, rs1554263625, rs766614772, rs1553620494, rs1555050158, rs1555050165, rs1555050171, rs1555050174, rs765556214, rs1402086660, rs1554645052, rs1555661648, rs1293246328, rs749494995, rs775592405, rs1553265189, rs1553242856, rs1553247374, rs1553241570, rs1553997065, rs1553998565, rs1380822792, rs1555028154, rs1555023232, rs1553194155, rs1553130904, rs1553152590, rs1553567864, rs1553638614, rs120074160, rs1554486894, rs1554767754, rs1554843977, rs1555443581, rs1555443600, rs1555439545, rs1555525088, rs770680174, rs1555889130, rs373178770, rs1555985532, rs1553519853, rs781325598, rs1410587479, rs1553638086, rs150259543, rs1554093891, rs1554121228, rs1554120498, rs1554121189, rs1212517874, rs1554770628, rs1555979158, rs1554770054, rs771610568, rs1451230055, rs1554770624, rs1555906707, rs1555906768, rs1555906781, rs1555907620, rs1555907623, rs1555907626, rs1555907653, rs1555907864, rs1554094145, rs1554202698, rs1554200722, rs773327091, rs1555607621, rs1555604778, rs1555607159, rs1555607682, rs1553364018, rs1553324416, rs1555411394, rs1554102556, rs1554122363, rs1555705966, rs1555103971, rs1555408401, rs1554461593, rs1554304254, rs1554120978, rs1047509819, rs1555982601, rs767774867, rs1554789246, rs1555111511, rs1555950676, rs1555954380, rs1555985649, rs1553194162, rs1553518509, rs1274633498, rs1554274371, rs1554122252, rs1554122458, rs1554122729, rs1554297905, rs1554776342, rs1554770046, rs1554770667, rs1554792556, rs1452715535, rs1555444885, rs1555534147, rs1427624649, rs1555611722, rs1555744282, rs1555706391, rs1178702025, rs1555984102, rs1554770589, rs1554121443, rs1559791842, rs1559824939, rs1555889127, rs1236702036, rs1553510280, rs1553511175, rs1553511226, rs1554150552, rs1554275163, rs1554201137, rs1553517991, rs1553518511, rs1553517984, rs1553518752, rs1554119814, rs1554122293, rs1554122341, rs1554122689, rs1554770243, rs1554770444, rs1557045250, rs959316981, rs1556270312, rs1553270640, rs978179634, rs1554093884, rs1491240980, rs1555943484, rs1554121453, rs1334099693, rs1554048616, rs1555660806, rs1555644480, rs1555651572, rs1567844992, rs1567855081, rs1567855669, rs1567855704, rs1567856045, rs1567856331, rs1567860075, rs1567860112, rs1567860640, rs1567860891, rs754919272, rs1567860919, rs1567861468, rs1567861489, rs1567861501, rs1567861894, rs1567863732, rs1567864750, rs1567877108, rs1567878511, rs758785463, rs1553808301, rs1553245038, rs1553789166, rs1553813646, rs1553631860, rs1554121265, rs1554770262, rs1555034768, rs1555984433, rs779009256, rs1553994814, rs1553996086, rs1553996072, rs1553270599, rs1553153291, rs760262127, rs1554119274, rs1554121878, rs1554387293, rs1554385203, rs757077698, rs750612085, rs1554776500, rs1564360978, rs1554776933, rs1554776938, rs1565278132, rs1567368243, rs1558478047, rs375695605, rs1558479778, rs1558501648, rs1565240833, rs114727354, rs1557591264, rs1557620758, rs1559099927, rs1561788984, rs369459721, rs1563831738, rs1562159088, rs1562159562, rs1562159599, rs1559094754, rs1559328283, rs755634856, rs1561784687, rs1554122296, rs1561789313, rs1562720119, rs1564363665, rs1561697465, rs1561785003, rs1561787845, rs1561789215, rs1554122305, rs1561784553, rs1561784560, rs1561787690, rs1554122888, rs749632782, rs1567139896, rs1569370887, rs1569371303, rs1564493599, rs1561875779, rs1569146542, rs1569146649, rs1275489527, rs1560115921, rs1468772495, rs749969789, rs1560108090, rs1569376809, rs1569355102, rs1560103306, rs1564365418, rs1559855453, rs1562928193, rs1558149913, rs1253072668, rs141976414, rs1558371790, rs1557898800, rs1567758622, rs1567844041, rs1567844114, rs1567920106, rs1567920209, rs138247472, rs1567974030, rs1567995650, rs1283838287, rs1568003569, rs1568006217, rs1568018905, rs1562505675, rs1561783309, rs1555980234, rs1559087186, rs1560966086, rs1560330387, rs769471341, rs1562493608, rs1562505335, rs1554121861, rs1554122200, rs1562957809, rs1568097623, rs1391600900, rs1568234874, rs1568235086, rs1555990955, rs1567870541, rs1557570794, rs1562869207, rs1571818248, rs1431778557, rs369691608, rs1595808957, rs1597665063, rs1597846084, rs1603401125, rs1603350606, rs1601946481, rs1601932069, rs1602880906, rs1602308324, rs1574554519, rs1573882268, rs1603198937, rs1558148010, rs1558498928, rs1569459580, rs1569380375, rs1560062082, rs1557889974, rs1558414255, rs756429763, rs781663444, rs1569016820, rs1569017025, rs1569017160, rs1557612048, rs1568504941, rs1581987022, rs1576983339, rs1599892470, rs1265340906, rs1602284689, rs1574949440, rs1576220938, rs1576280892, rs1576288424, rs1574459612, rs1574511051, rs1575654528, rs1577094794, rs1294683568, rs771819481, rs1580984895, rs1581338441, rs1580988138, rs1581980317, rs1581986872, rs1554121207, rs1581987268, rs1581987476, rs1581987885, rs763770519, rs1581991929, rs1581992099, rs1581992998, rs1581995453, rs1554122242, rs1581996778, rs1581997228, rs1588735247, rs1555980467, rs1555985742, rs1601319086, rs1601970168, rs1574451881, rs876661168, rs1576994053, rs1573589807, rs1581036396, rs1601267617, rs1572531830, rs1573483715, rs1590954686, rs1601315812, rs1573965358, rs1573972562, rs529087882, rs1570609440, rs1598940393, rs1575333081, rs1576028676, rs1596476657, rs1599375711, rs1603290366, rs1603060007, rs1603069440, rs1592939069, rs1591612223, rs2062994512, rs373701249, rs1600471396, rs1600501018, rs1600504088, rs1600514073, rs748436953, rs765723607, rs758170522, rs1561785045, rs1357591960, rs1591609136, rs1596891223, rs1579370234, rs2047850664, rs1579109565, rs1870202051, rs1574887674, rs778229060, rs1572531281, rs1570622663, rs1573501865, rs1576086299, rs1576164991, rs1574907198, rs1576656734, rs1554121438, rs1581995425, rs1581996813, rs1582001015, rs1588324025, rs1591371152, rs1590008294, rs1590956245, rs1590028691, rs1591606580, rs1591611001, rs1591612317, rs1591612370, rs763436882, rs997044541, rs1595897117, rs747706524, rs1579377990, rs1201878175, rs1894051550, rs1572531730, rs1579576029, rs1577017863, rs752545577, rs1582461267, rs1589460606, rs1588727276, rs1598620094, rs1599368323, rs1600082188, rs1601319352, rs1598226304, rs2076013475, rs2076017638, rs1600596180, rs1554121932, rs1680676671, rs1570607996, rs1382444181, rs1570640673, rs1574994308, rs1596667777, rs1602226289, rs1595629181, rs1595609005, rs1227643933, rs1572705473, rs1570621899, rs1722830922, rs1575094649, rs1417035592, rs1581997098, rs1589457762, rs1598211790, rs758726258, rs1601071971, rs863224922, rs1586692481, rs1586692548, rs1586692551, rs1580988074, rs1594129609, rs1588732344, rs1579368865, rs1586660389, rs1586660370, rs1586660338, rs1586657848, rs1586660381, rs1791701214, rs752676391, rs1680673822, rs758098717, rs1726676630, rs762288077, rs1759964009, rs1760905766, rs1761021165, rs1554121934, rs2055849544, rs1049773, rs587784300, rs1861628072, rs1761241410, rs1064797322, rs1948652423, rs2059194330, rs1777174302, rs2054280202, rs2081190512, rs772665884, rs1400164869, rs1861593395, rs1760897843, rs1761087122, rs1388355040, rs2068797192, rs1777175608, rs376898131
Keppen-lubinsky syndrome	KEPPEN-LUBINSKY SYNDROME, Keppen-Lubinsky syndrome	rs786204794, rs786204795, rs1556023562	25620207
Lipodystrophy	Familial generalized lipodystrophy	rs553668, rs766817317
Microcephaly	Microcephaly	rs397704721, rs267607176, rs267607177, rs397704725, rs267606717, rs267606718, rs199422202, rs121434311, rs199422203, rs199422126, rs387906274, rs121434305, rs199422125, rs199422135, rs189678019, rs199422184, rs137852994, rs137852995, rs137852996, rs137852997, rs145489194, rs80338860, rs137852494, rs121918609, rs199422207, rs199422206, rs29001566, rs864321658, rs199422138, rs199422139, rs199422141, rs199422144, rs199422147, rs199422151, rs199422152, rs199422153, rs199422157, rs199422159, rs199422160, rs199422161, rs140602858, rs199422164, rs199422165, rs148294838, rs199422134, rs199422168, rs199422172, rs199422173, rs199422131, rs199422177, rs199422180, rs199422185, rs199422186, rs199422187, rs143931757, rs199422189, rs199422192, rs199422194, rs199422195, rs199422196, rs199422197, rs199422199, rs753597039, rs1488084787, rs387906961, rs755862917, rs387907082, rs587776899, rs387907083, rs587776900, rs587776901, rs387907084, rs863223322, rs764201220, rs202247811, rs763915472, rs587776986, rs587777036, rs398122971, rs374351172, rs373278668, rs398122976, rs121909123, rs587783393, rs730882076, rs587783211, rs144716013, rs606231255, rs587783215, rs587783216, rs587783220, rs587783221, rs587783225, rs587783227, rs587783228, rs587783230, rs587783238, rs587783239, rs587783240, rs587783245, rs587783247, rs587783248, rs587783258, rs587783259, rs587783263, rs587783265, rs587783268, rs587783269, rs587783272, rs587783275, rs587783277, rs587783278, rs587783280, rs587783282, rs587783283, rs587783285, rs587783287, rs587783288, rs587783289, rs587783292, rs587783295, rs587784452, rs587783741, rs587783735, rs587783392, rs587783390, rs587783387, rs587783410, rs202058504, rs587783423, rs587783421, rs587783414, rs587784553, rs587784558, rs587784546, rs587784549, rs587784554, rs587784412, rs876661307, rs869025200, rs747831095, rs748529285, rs797045316, rs797045315, rs797045314, rs759632528, rs797045313, rs797045311, rs754282058, rs797045441, rs797045454, rs797045430, rs869312853, rs797046109, rs767399782, rs863225127, rs863225464, rs863225465, rs780270096, rs864321621, rs864321620, rs775277800, rs879253817, rs869312824, rs761447719, rs753406334, rs147622433, rs199422137, rs879255522, rs879255524, rs879255523, rs886037892, rs886037893, rs886037894, rs886037895, rs199422169, rs886041709, rs886041282, rs138228629, rs759188041, rs769688376, rs1057517688, rs1057519087, rs1057518268, rs933106143, rs201362977, rs754909135, rs1057520873, rs1060499758, rs1060499757, rs199422146, rs748016594, rs1085307120, rs763715733, rs1064795945, rs763800571, rs1554728351, rs1553227021, rs555866170, rs1553895368, rs1334947797, rs769818500, rs1321892596, rs1553227645, rs1404276011, rs1553228275, rs1554471681, rs1554496609, rs1555420891, rs1555418825, rs587784548, rs1555723585, rs199736219, rs745997770, rs765275884, rs1553924800, rs1554730137, rs1229568621, rs1482100822, rs979186313, rs758157294, rs1555294652, rs1555299107, rs1553264033, rs1553259539, rs1553254322, rs1553259528, rs981349334, rs1553264036, rs1553253022, rs754267846, rs776034810, rs1342429887, rs752140135, rs1006898944, rs571640983, rs1477524771, rs763909256, rs199910503, rs1553223496, rs759663956, rs1553446603, rs1555139372, rs1555143325, rs1350194762, rs1555141158, rs1553225179, rs769481947, rs769364943, rs748011724, rs1334301723, rs746341112, rs149225624, rs765113367, rs1567024512, rs142865061, rs772050241, rs201721894, rs1557966012, rs1379578836, rs1568334868, rs1185537869, rs1602333390, rs1163303148, rs774338373, rs770540184, rs1571600045, rs1571601267, rs1571602991, rs1588472215, rs1599841026, rs1558328287, rs1571600860, rs1571596976, rs1309880692, rs1435239428, rs1588634016, rs1751797979, rs1810830776, rs1815354949, rs1949984655, rs886039658, rs1943461045, rs777711720, rs2031759596, rs1555710223, rs1221031683, rs774069989, rs2058919680, rs1170413397, rs1213710245, rs1599851667, rs1599760058, rs1971033478, rs746967357
Scoliosis	Scoliosis, unspecified	rs1057518828, rs147296805, rs758163506, rs1555613564, rs1596852902, rs1596853067, rs1596853085

Unknown
Disease term	Disease name	Evidence	References	Source
Mental depression	Mental Depression, Depressive disorder		22308328, 20943350	ClinVar
Spastic tetraparesis	Spastic tetraparesis			ClinVar
Metabolic Syndrome	Metabolic Syndrome			GWAS
Gout	Gout			GWAS
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA
Dementia	Dementia			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Alcoholism	Associate	21307845
Bipolar Disorder	Associate	19567891
Breast Neoplasms	Associate	15603589
Channelopathies	Associate	29852244
Chronic Pain	Associate	36261449
Cicatrix Hypertrophic	Associate	30320389
Cognition Disorders	Associate	36071510
Congenital Abnormalities	Associate	36071510
Cystitis Interstitial	Associate	30973927
Developmental Disabilities	Associate	29852244
Down Syndrome	Associate	25620207, 9037601
Drug Related Side Effects and Adverse Reactions	Associate	34871222
Dyskinesias	Associate	29852244
Dystonia	Associate	29852244
Glycogen Storage Disease Type IV	Associate	12034888
Heart Valve Diseases	Associate	33518654
Heroin Dependence	Associate	36261449
Hyperkinesis	Associate	29852244
Intellectual Disability	Associate	36071510
Lipodystrophy	Associate	25620207
Lymphedema	Associate	28252570
Malformations of Cortical Development	Associate	16418593
Mastodynia	Associate	24392765
Movement Disorders	Associate	29852244
Neoplasms	Associate	26959888, 36261449
Nerve Degeneration	Associate	34941945
Nervous System Diseases	Associate	36835019
Obsessive Compulsive Disorder	Associate	36071510
Pain	Associate	34283174, 36261449
Paine syndrome	Associate	34283174
Psychotic Disorders	Associate	19567891
Stiff Person Syndrome	Associate	36071510
Uniparental Disomy	Associate	33710394
Weaver syndrome	Associate	29852244