KCNJ6 (potassium inwardly rectifying channel subfamily J member 6)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 3763 |
| Gene name | Potassium inwardly rectifying channel subfamily J member 6 |
| Gene symbol | KCNJ6 |
| Synonyms (NCBI Gene) |
BIR1GIRK-2GIRK2KATP-2KATP2KCNJ7KIR3.2KPLBShiGIRK2
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| Chromosome | 21 |
| Chromosome location | 21q22.13 |
| Summary | This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulat |
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miRNA
miRNA information provided by mirtarbase database.
428
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P48051 | |||||||||||||||
| Protein name | G protein-activated inward rectifier potassium channel 2 (GIRK-2) (BIR1) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (Potassium channel, inwardly rectifying subfamily J member 6) | |||||||||||||||
| Protein function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potass | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas. {ECO:0000269|PubMed:7592809}. | |||||||||||||||
| Sequence |
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| Sequence length | 423 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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