Gene Gene information from NCBI Gene database.
Entrez ID 375743
Gene name Protein prenyltransferase alpha subunit repeat containing 1
Gene symbol PTAR1
Synonyms (NCBI Gene)
-
Chromosome 9
Chromosome location 9q21.12
miRNA miRNA information provided by mirtarbase database.
972
miRTarBase ID miRNA Experiments Reference
MIRT003174 hsa-miR-210-3p immunoprecipitaionMicroarrayqRT-PCR 19826008
MIRT023612 hsa-miR-1-3p Microarray 18668037
MIRT025704 hsa-miR-7-5p Microarray 17612493
MIRT030760 hsa-miR-21-5p Microarray 18591254
MIRT051343 hsa-miR-15a-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0004659 Function Prenyltransferase activity IEA
GO:0004663 Function Rab geranylgeranyltransferase activity IBA
GO:0005737 Component Cytoplasm IBA
GO:0005739 Component Mitochondrion HTP 34800366
GO:0008318 Function Protein prenyltransferase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
621024 30449 ENSG00000188647
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z6K3
Protein name Protein prenyltransferase alpha subunit repeat-containing protein 1
PDB 6J6X , 6J74 , 6J7F , 6J7X , 6O60
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01239 PPTA 121 150 Protein prenyltransferase alpha subunit repeat Repeat
PF01239 PPTA 177 208 Protein prenyltransferase alpha subunit repeat Repeat
PF01239 PPTA 216 247 Protein prenyltransferase alpha subunit repeat Repeat
PF01239 PPTA 292 323 Protein prenyltransferase alpha subunit repeat Repeat
Sequence
MAETSEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWC
VKFLLPYVHNKLLLYRTRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPI
KDLHLGKLALTKFPKSPETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEE
MEVCGEAAGRYPSNYNAWSHRIWVLQHL
AKLDVKILLDELSSTKHWASMHVSDHSGFHYR
QFLLKSL
ISQTVIDSSVMEQNPLRSEPALVPPKDEEAAVSTEEPRINLPHLLEEEVEFST
DLIDSYPGHETLWCHRRHIFYLQ
HHLNAGSQLSQAMEVDGLNDSSKQGYSQETKRLKRTP
VPDSLGLEMEHRFIDQVLSTCRNVEQARFASAYRKWLVTLSQ
Sequence length 402
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
MAJOR DEPRESSIVE DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations