Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	374879
Gene name	Zinc finger protein 699
Gene symbol	ZNF699
Synonyms (NCBI Gene)	DEGCAGShang
Chromosome	19
Chromosome location	19p13.2

114

Show/Hide all (114)

miRTarBase ID	miRNA	Experiments	Reference
MIRT651032	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT651031	hsa-miR-764	HITS-CLIP	23824327
MIRT651030	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT651029	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT651028	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT651027	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT651026	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT651025	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT651024	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT651023	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT651022	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT651021	hsa-miR-4454	HITS-CLIP	23824327
MIRT651020	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT651019	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT616335	hsa-miR-4462	HITS-CLIP	23824327
MIRT616334	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT616333	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT616332	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616335	hsa-miR-4462	HITS-CLIP	23824327
MIRT616334	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT616333	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT616332	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT532859	hsa-miR-181b-5p	PAR-CLIP	22012620
MIRT532858	hsa-miR-181c-5p	PAR-CLIP	22012620
MIRT532857	hsa-miR-181d-5p	PAR-CLIP	22012620
MIRT532856	hsa-miR-181a-5p	PAR-CLIP	22012620
MIRT532855	hsa-miR-4262	PAR-CLIP	22012620
MIRT532854	hsa-miR-600	PAR-CLIP	22012620
MIRT532853	hsa-miR-376a-3p	PAR-CLIP	22012620
MIRT532852	hsa-miR-376b-3p	PAR-CLIP	22012620
MIRT532851	hsa-miR-155-3p	PAR-CLIP	22012620
MIRT532850	hsa-miR-3685	PAR-CLIP	22012620
MIRT532849	hsa-miR-384	PAR-CLIP	22012620
MIRT532848	hsa-miR-3133	PAR-CLIP	22012620
MIRT532847	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT532846	hsa-miR-383-5p	PAR-CLIP	22012620
MIRT532845	hsa-miR-5694	PAR-CLIP	22012620
MIRT532844	hsa-miR-95-5p	PAR-CLIP	22012620
MIRT616332	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT616335	hsa-miR-4462	HITS-CLIP	27418678
MIRT616334	hsa-miR-514a-3p	HITS-CLIP	27418678
MIRT616333	hsa-miR-514b-3p	HITS-CLIP	27418678
MIRT651032	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT651031	hsa-miR-764	HITS-CLIP	23824327
MIRT651030	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT651029	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT651028	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT651027	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT651026	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT651025	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT651024	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT651023	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT651022	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT651021	hsa-miR-4454	HITS-CLIP	23824327
MIRT651020	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT651019	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT616335	hsa-miR-4462	HITS-CLIP	23824327
MIRT616334	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT616333	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT616332	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT616335	hsa-miR-4462	HITS-CLIP	23824327
MIRT616334	hsa-miR-514a-3p	HITS-CLIP	23824327
MIRT616333	hsa-miR-514b-3p	HITS-CLIP	23824327
MIRT616332	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT532859	hsa-miR-181b-5p	PAR-CLIP	22012620
MIRT532858	hsa-miR-181c-5p	PAR-CLIP	22012620
MIRT532857	hsa-miR-181d-5p	PAR-CLIP	22012620
MIRT532856	hsa-miR-181a-5p	PAR-CLIP	22012620
MIRT532855	hsa-miR-4262	PAR-CLIP	22012620
MIRT532854	hsa-miR-600	PAR-CLIP	22012620
MIRT532853	hsa-miR-376a-3p	PAR-CLIP	22012620
MIRT532852	hsa-miR-376b-3p	PAR-CLIP	22012620
MIRT532851	hsa-miR-155-3p	PAR-CLIP	22012620
MIRT532850	hsa-miR-3685	PAR-CLIP	22012620
MIRT532849	hsa-miR-384	PAR-CLIP	22012620
MIRT532848	hsa-miR-3133	PAR-CLIP	22012620
MIRT532847	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT532846	hsa-miR-383-5p	PAR-CLIP	22012620
MIRT532845	hsa-miR-5694	PAR-CLIP	22012620
MIRT532844	hsa-miR-95-5p	PAR-CLIP	22012620
MIRT1536140	hsa-miR-106a	CLIP-seq
MIRT1536141	hsa-miR-106b	CLIP-seq
MIRT1536142	hsa-miR-144	CLIP-seq
MIRT1536143	hsa-miR-17	CLIP-seq
MIRT1536144	hsa-miR-181a	CLIP-seq
MIRT1536145	hsa-miR-181b	CLIP-seq
MIRT1536146	hsa-miR-181c	CLIP-seq
MIRT1536147	hsa-miR-181d	CLIP-seq
MIRT1536148	hsa-miR-20a	CLIP-seq
MIRT1536149	hsa-miR-20b	CLIP-seq
MIRT1536150	hsa-miR-342-3p	CLIP-seq
MIRT1536151	hsa-miR-3609	CLIP-seq
MIRT1536152	hsa-miR-376a	CLIP-seq
MIRT1536153	hsa-miR-376b	CLIP-seq
MIRT1536154	hsa-miR-3909	CLIP-seq
MIRT1536155	hsa-miR-4509	CLIP-seq
MIRT1536156	hsa-miR-4672	CLIP-seq
MIRT1536157	hsa-miR-4695-3p	CLIP-seq
MIRT1536158	hsa-miR-4712-3p	CLIP-seq
MIRT1536159	hsa-miR-4744	CLIP-seq
MIRT1536160	hsa-miR-4768-5p	CLIP-seq
MIRT1536161	hsa-miR-4796-3p	CLIP-seq
MIRT1536162	hsa-miR-519d	CLIP-seq
MIRT1536163	hsa-miR-548ah	CLIP-seq
MIRT1536164	hsa-miR-93	CLIP-seq
MIRT1536142	hsa-miR-144	CLIP-seq
MIRT1536144	hsa-miR-181a	CLIP-seq
MIRT1536145	hsa-miR-181b	CLIP-seq
MIRT1536146	hsa-miR-181c	CLIP-seq
MIRT1536147	hsa-miR-181d	CLIP-seq
MIRT1536152	hsa-miR-376a	CLIP-seq
MIRT1536153	hsa-miR-376b	CLIP-seq
MIRT1536157	hsa-miR-4695-3p	CLIP-seq
MIRT1536158	hsa-miR-4712-3p	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
609571	24750	ENSG00000196110

Q32M78

Protein name

Zinc finger protein 699 (Hangover homolog)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	18 → 59	KRAB box	Family
PF00096	zf-C2H2	195 → 217	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	279 → 301	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	307 → 329	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	335 → 357	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	363 → 385	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	391 → 413	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	447 → 469	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	475 → 497	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	503 → 525	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	531 → 553	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	559 → 581	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	587 → 609	Zinc finger, C2H2 type	Domain

Sequence

MEEERKTAELQKNRIQDSVVFEDVAVDFTQEEWALLDLAQRNLYRDVMLENFQNLASLGY
PLHTPHLISQWEQEEDLQTVKRELIQGIFMGEHREGFETQLKTNESVASQDICGEKISNE
QKIVRFKRNDSWFSSLHENQESCGIDYQNKSHERHLRNHMVENIYECYEENQDGQTFSQV
PNLDSLKRNTEVKSCECHECGKAFVDHSSLKSHIRSHTGSKPYQCKECGKAFHFLACFKK
HMKTPTEEKPYECKECTKAFSCSSFFRAHMKIHIGKTNYECKECGKGFSCSSSLTEHKRI
HSGDKPYECKECGKAFSCSSSLSKHKRIHSGDKPYECKECGKAFSSSSHLIIHIRIHTGE
KPYECKECGKAFSESSKLTVHGRTHTGEKPYKCKECGKAYNCPSSLSIHMRKHTGEKPYE
CLECGKAFYLPTSLNTHVKNQSREKPYECKECGKAFSCPSSFRAHVRDHTGKIQYECKEC
GKTFSRSSSLTEHLRTHSGEKPYECKECGKAFISSSHLTVHIRTHTGEKPYECKKCGKAF
IYPSALRIHMRTHTGEKPYECKECGKAFRHSSYLTVHARMHTGEKPFECLECGKAFSCPS
SFRRHVRSHTGEKPYECKECGKAFVCPAYFRRHVKTHTRENI

Sequence length

642

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
DEGCAGS syndrome	Pathogenic	rs2144976149, rs2144974768, rs1366191812, rs2144980732, rs2513397063, rs2066284895, rs2513391263	RCV001572618 RCV001572620 RCV001572621 RCV001572622 RCV002287210 RCV003335809 RCV004595131	★★★★★ ★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
ZNF699-related disorder	Likely pathogenic	rs2513391862	RCV003406213	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ANEMIA, DIAMOND-BLACKFAN	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diamond-Blackfan anemia	Conflicting classifications of pathogenicity	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-SPECIFIC SYNDROMIC INTELLECTUAL DISABILITY	—	Disgenet, Orphanet Disgenet, Orphanet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Alcoholism	Associate	35205213	★★★★★ ★☆☆☆☆ Found in Text Mining only
Body Dysmorphic Disorders	Associate	35205213	★★★★★ ★☆☆☆☆ Found in Text Mining only
Developmental Disabilities	Associate	35205213	★★★★★ ★☆☆☆☆ Found in Text Mining only
Syndrome	Associate	35205213	★★★★★ ★☆☆☆☆ Found in Text Mining only
Urogenital Abnormalities	Associate	35205213	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF699 (zinc finger protein 699)