Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	374868
Gene name	ATPase phospholipid transporting 9B (putative)
Gene symbol	ATP9B
Synonyms (NCBI Gene)	ATPASEPATPIIBHUSSY-20NEO1LhMMR1
Chromosome	18
Chromosome location	18q23

Show/Hide all (76)

miRTarBase ID	miRNA	Experiments
MIRT810120	hsa-miR-101	CLIP-seq
MIRT810121	hsa-miR-103a	CLIP-seq
MIRT810122	hsa-miR-107	CLIP-seq
MIRT810123	hsa-miR-1184	CLIP-seq
MIRT810124	hsa-miR-1301	CLIP-seq
MIRT810125	hsa-miR-144	CLIP-seq
MIRT810126	hsa-miR-146b-3p	CLIP-seq
MIRT810127	hsa-miR-3120-5p	CLIP-seq
MIRT810128	hsa-miR-3138	CLIP-seq
MIRT810129	hsa-miR-3151	CLIP-seq
MIRT810130	hsa-miR-3173-5p	CLIP-seq
MIRT810131	hsa-miR-3181	CLIP-seq
MIRT810132	hsa-miR-3194-5p	CLIP-seq
MIRT810133	hsa-miR-342-5p	CLIP-seq
MIRT810134	hsa-miR-3606	CLIP-seq
MIRT810135	hsa-miR-378g	CLIP-seq
MIRT810136	hsa-miR-3944-3p	CLIP-seq
MIRT810137	hsa-miR-4292	CLIP-seq
MIRT810138	hsa-miR-4300	CLIP-seq
MIRT810139	hsa-miR-4310	CLIP-seq
MIRT810140	hsa-miR-4436b-3p	CLIP-seq
MIRT810141	hsa-miR-4437	CLIP-seq
MIRT810142	hsa-miR-4447	CLIP-seq
MIRT810143	hsa-miR-4462	CLIP-seq
MIRT810144	hsa-miR-4472	CLIP-seq
MIRT810145	hsa-miR-4481	CLIP-seq
MIRT810146	hsa-miR-4491	CLIP-seq
MIRT810147	hsa-miR-4657	CLIP-seq
MIRT810148	hsa-miR-4660	CLIP-seq
MIRT810149	hsa-miR-4664-5p	CLIP-seq
MIRT810150	hsa-miR-4674	CLIP-seq
MIRT810151	hsa-miR-4682	CLIP-seq
MIRT810152	hsa-miR-4731-5p	CLIP-seq
MIRT810153	hsa-miR-4745-5p	CLIP-seq
MIRT810154	hsa-miR-4750	CLIP-seq
MIRT810155	hsa-miR-4758-5p	CLIP-seq
MIRT810156	hsa-miR-4800-5p	CLIP-seq
MIRT810157	hsa-miR-486-3p	CLIP-seq
MIRT810158	hsa-miR-491-5p	CLIP-seq
MIRT810159	hsa-miR-5047	CLIP-seq
MIRT810160	hsa-miR-558	CLIP-seq
MIRT810161	hsa-miR-602	CLIP-seq
MIRT810162	hsa-miR-633	CLIP-seq
MIRT810163	hsa-miR-637	CLIP-seq
MIRT810164	hsa-miR-874	CLIP-seq
MIRT810165	hsa-miR-920	CLIP-seq
MIRT810120	hsa-miR-101	CLIP-seq
MIRT810125	hsa-miR-144	CLIP-seq
MIRT810134	hsa-miR-3606	CLIP-seq
MIRT2178653	hsa-miR-4330	CLIP-seq
MIRT2178654	hsa-miR-4426	CLIP-seq
MIRT2178655	hsa-miR-4647	CLIP-seq
MIRT2178656	hsa-miR-4662b	CLIP-seq
MIRT2178657	hsa-miR-582-5p	CLIP-seq
MIRT810162	hsa-miR-633	CLIP-seq
MIRT810126	hsa-miR-146b-3p	CLIP-seq
MIRT810130	hsa-miR-3173-5p	CLIP-seq
MIRT810135	hsa-miR-378g	CLIP-seq
MIRT810137	hsa-miR-4292	CLIP-seq
MIRT2444479	hsa-miR-4757-5p	CLIP-seq
MIRT810164	hsa-miR-874	CLIP-seq
MIRT2482251	hsa-miR-186	CLIP-seq
MIRT2482252	hsa-miR-3126-5p	CLIP-seq
MIRT2482253	hsa-miR-4419a	CLIP-seq
MIRT2482254	hsa-miR-4427	CLIP-seq
MIRT2482255	hsa-miR-4510	CLIP-seq
MIRT2482256	hsa-miR-4517	CLIP-seq
MIRT2482257	hsa-miR-4680-3p	CLIP-seq
MIRT2482251	hsa-miR-186	CLIP-seq
MIRT2482252	hsa-miR-3126-5p	CLIP-seq
MIRT2482253	hsa-miR-4419a	CLIP-seq
MIRT2482254	hsa-miR-4427	CLIP-seq
MIRT2675756	hsa-miR-4449	CLIP-seq
MIRT2482255	hsa-miR-4510	CLIP-seq
MIRT2482256	hsa-miR-4517	CLIP-seq
MIRT2482257	hsa-miR-4680-3p	CLIP-seq

Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000287	Function	Magnesium ion binding	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005768	Component	Endosome	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005802	Component	Trans-Golgi network	IBA
GO:0005802	Component	Trans-Golgi network	IDA	21914794
GO:0005802	Component	Trans-Golgi network	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0006869	Process	Lipid transport	IEA
GO:0006890	Process	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	IBA
GO:0006897	Process	Endocytosis	IBA
GO:0015914	Process	Phospholipid transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0045332	Process	Phospholipid translocation	IBA
GO:0045332	Process	Phospholipid translocation	NAS	21914794
GO:0046872	Function	Metal ion binding	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	21914794
GO:0140326	Function	ATPase-coupled intramembrane lipid transporter activity	IBA
GO:0140326	Function	ATPase-coupled intramembrane lipid transporter activity	IEA

MIM	HGNC	e!Ensembl
614446	13541	ENSG00000166377

O43861

Protein name

Probable phospholipid-transporting ATPase IIB (EC 7.6.2.1) (ATPase class II type 9B)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16209	PhoLip_ATPase_N	109 → 183	Phospholipid-translocating ATPase N-terminal	Family
PF00122	E1-E2_ATPase	206 → 441		Family
PF00702	Hydrolase	464 → 886		Domain
PF16212	PhoLip_ATPase_C	900 → 1140	Phospholipid-translocating P-type ATPase C-terminal	Family

Sequence

MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE
GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL
GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV
EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV
YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV
MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII
PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF
KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR
IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES
VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD
VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK
VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS
HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ
CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS
LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL
YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS
IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY
VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP
SYCKLAS

Sequence length

1147

Interactions

View interactions

	Reactome
			Ion transport by P-type ATPases

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FRONTOTEMPORAL DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Alzheimer Disease	Associate	26625115	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Associate	23285077	★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Associate	23285077	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pemphigus Benign Familial	Associate	25837627	★★★★★ ★☆☆☆☆ Found in Text Mining only

ATP9B (ATPase phospholipid transporting 9B (putative))