Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3745
Gene name Gene Name - the full gene name approved by the HGNC.	Potassium voltage-gated channel subfamily B member 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KCNB1
Synonyms (NCBI Gene) Gene synonyms aliases	DEE26, DRK1, Kv2.1
Chromosome Chromosome number	20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	20q13.13
Summary Summary of gene provided in NCBI Entrez Gene.	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuro

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1568658507	T>C	Likely-pathogenic	Coding sequence variant, missense variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT707271	hsa-miR-548c-3p	HITS-CLIP	21572407
MIRT707269	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT707270	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707268	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707267	hsa-miR-4639-5p	HITS-CLIP	21572407
MIRT707266	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT607815	hsa-miR-8485	HITS-CLIP	23313552
MIRT607814	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT607813	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT607812	hsa-miR-603	HITS-CLIP	23313552
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23313552
MIRT612844	hsa-miR-5695	HITS-CLIP	23313552
MIRT607811	hsa-miR-3941	HITS-CLIP	23313552
MIRT607815	hsa-miR-8485	HITS-CLIP	23313552
MIRT607814	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT607813	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT607812	hsa-miR-603	HITS-CLIP	23313552
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23313552
MIRT612844	hsa-miR-5695	HITS-CLIP	23313552
MIRT607811	hsa-miR-3941	HITS-CLIP	23313552
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT667786	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT667785	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT667784	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT667783	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT667782	hsa-miR-6505-5p	HITS-CLIP	23824327
MIRT667781	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT657062	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT657061	hsa-let-7a-2-3p	HITS-CLIP	23824327
MIRT657060	hsa-let-7g-3p	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612846	hsa-miR-1305	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612846	hsa-miR-1305	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612846	hsa-miR-1305	HITS-CLIP	23824327
MIRT607815	hsa-miR-8485	HITS-CLIP	23824327
MIRT607812	hsa-miR-603	HITS-CLIP	23824327
MIRT612845	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT612844	hsa-miR-5695	HITS-CLIP	23824327
MIRT607816	hsa-miR-6776-3p	HITS-CLIP	24906430
MIRT607815	hsa-miR-8485	HITS-CLIP	24906430
MIRT607814	hsa-miR-329-3p	HITS-CLIP	24906430
MIRT607813	hsa-miR-362-3p	HITS-CLIP	24906430
MIRT607812	hsa-miR-603	HITS-CLIP	24906430
MIRT607811	hsa-miR-3941	HITS-CLIP	24906430
MIRT567069	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT567068	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT567067	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT567066	hsa-miR-3666	PAR-CLIP	20371350
MIRT567065	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT567064	hsa-miR-4295	PAR-CLIP	20371350
MIRT567063	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT567062	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT567061	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT567060	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT567059	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT567058	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT567057	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT567056	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT567055	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT567054	hsa-miR-520f-3p	PAR-CLIP	20371350
MIRT567053	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT567052	hsa-miR-3609	PAR-CLIP	20371350
MIRT567051	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT567050	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT567049	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT567048	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT567047	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT567046	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT567045	hsa-miR-6871-5p	PAR-CLIP	20371350
MIRT567044	hsa-miR-3117-5p	PAR-CLIP	20371350
MIRT567043	hsa-miR-4696	PAR-CLIP	20371350
MIRT567042	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT567041	hsa-miR-3153	PAR-CLIP	20371350
MIRT567040	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT567039	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT567038	hsa-miR-4473	PAR-CLIP	20371350
MIRT567037	hsa-miR-514a-3p	PAR-CLIP	20371350
MIRT567036	hsa-miR-514b-3p	PAR-CLIP	20371350
MIRT450824	hsa-miR-548aa	PAR-CLIP	22100165
MIRT450823	hsa-miR-548ap-3p	PAR-CLIP	22100165
MIRT450822	hsa-miR-548t-3p	PAR-CLIP	22100165
MIRT450821	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT450820	hsa-miR-552-5p	PAR-CLIP	22100165
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	27418678
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	27418678
MIRT575005	hsa-miR-5695	HITS-CLIP	27418678
MIRT575005	hsa-miR-5695	HITS-CLIP	27418678
MIRT575007	hsa-miR-603	HITS-CLIP	27418678
MIRT575007	hsa-miR-603	HITS-CLIP	27418678
MIRT575008	hsa-miR-8485	HITS-CLIP	27418678
MIRT575008	hsa-miR-8485	HITS-CLIP	27418678
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	28735896
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	28735896
MIRT575005	hsa-miR-5695	HITS-CLIP	28735896
MIRT575005	hsa-miR-5695	HITS-CLIP	28735896
MIRT575007	hsa-miR-603	HITS-CLIP	28735896
MIRT575007	hsa-miR-603	HITS-CLIP	28735896
MIRT575008	hsa-miR-8485	HITS-CLIP	28735896
MIRT575008	hsa-miR-8485	HITS-CLIP	28735896
MIRT707271	hsa-miR-548c-3p	HITS-CLIP	21572407
MIRT707269	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT707270	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707268	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707267	hsa-miR-4639-5p	HITS-CLIP	21572407
MIRT707266	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT575008	hsa-miR-8485	HITS-CLIP	23313552
MIRT607814	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT607813	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT575007	hsa-miR-603	HITS-CLIP	23313552
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23313552
MIRT575005	hsa-miR-5695	HITS-CLIP	23313552
MIRT607811	hsa-miR-3941	HITS-CLIP	23313552
MIRT575008	hsa-miR-8485	HITS-CLIP	23313552
MIRT607814	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT607813	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT575007	hsa-miR-603	HITS-CLIP	23313552
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23313552
MIRT575005	hsa-miR-5695	HITS-CLIP	23313552
MIRT607811	hsa-miR-3941	HITS-CLIP	23313552
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT667786	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT667785	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT667784	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT667783	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT667782	hsa-miR-6505-5p	HITS-CLIP	23824327
MIRT667781	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT657062	hsa-miR-582-5p	HITS-CLIP	23824327
MIRT657061	hsa-let-7a-2-3p	HITS-CLIP	23824327
MIRT657060	hsa-let-7g-3p	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612846	hsa-miR-1305	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612846	hsa-miR-1305	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT612850	hsa-miR-7-1-3p	HITS-CLIP	23824327
MIRT612849	hsa-miR-7-2-3p	HITS-CLIP	23824327
MIRT612848	hsa-miR-1250-3p	HITS-CLIP	23824327
MIRT612847	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT612846	hsa-miR-1305	HITS-CLIP	23824327
MIRT575008	hsa-miR-8485	HITS-CLIP	23824327
MIRT575007	hsa-miR-603	HITS-CLIP	23824327
MIRT575006	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT575005	hsa-miR-5695	HITS-CLIP	23824327
MIRT567069	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT567068	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT567067	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT567066	hsa-miR-3666	PAR-CLIP	20371350
MIRT567065	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT567064	hsa-miR-4295	PAR-CLIP	20371350
MIRT567063	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT567062	hsa-miR-17-5p	PAR-CLIP	20371350
MIRT567061	hsa-miR-20b-5p	PAR-CLIP	20371350
MIRT567060	hsa-miR-106a-5p	PAR-CLIP	20371350
MIRT567059	hsa-miR-20a-5p	PAR-CLIP	20371350
MIRT567058	hsa-miR-106b-5p	PAR-CLIP	20371350
MIRT567057	hsa-miR-93-5p	PAR-CLIP	20371350
MIRT567056	hsa-miR-526b-3p	PAR-CLIP	20371350
MIRT567055	hsa-miR-519d-3p	PAR-CLIP	20371350
MIRT567054	hsa-miR-520f-3p	PAR-CLIP	20371350
MIRT567053	hsa-miR-302c-3p	PAR-CLIP	20371350
MIRT567052	hsa-miR-3609	PAR-CLIP	20371350
MIRT567051	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT567050	hsa-miR-4796-3p	PAR-CLIP	20371350
MIRT567049	hsa-miR-519a-3p	PAR-CLIP	20371350
MIRT567048	hsa-miR-519b-3p	PAR-CLIP	20371350
MIRT567047	hsa-miR-519c-3p	PAR-CLIP	20371350
MIRT567046	hsa-miR-512-3p	PAR-CLIP	20371350
MIRT567045	hsa-miR-6871-5p	PAR-CLIP	20371350
MIRT567044	hsa-miR-3117-5p	PAR-CLIP	20371350
MIRT567043	hsa-miR-4696	PAR-CLIP	20371350
MIRT567042	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT567041	hsa-miR-3153	PAR-CLIP	20371350
MIRT567040	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT567039	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT567038	hsa-miR-4473	PAR-CLIP	20371350
MIRT567037	hsa-miR-514a-3p	PAR-CLIP	20371350
MIRT567036	hsa-miR-514b-3p	PAR-CLIP	20371350
MIRT450824	hsa-miR-548aa	PAR-CLIP	22100165
MIRT450823	hsa-miR-548ap-3p	PAR-CLIP	22100165
MIRT450822	hsa-miR-548t-3p	PAR-CLIP	22100165
MIRT450821	hsa-miR-570-3p	PAR-CLIP	22100165
MIRT450820	hsa-miR-552-5p	PAR-CLIP	22100165
MIRT1080431	hsa-miR-1289	CLIP-seq
MIRT1080432	hsa-miR-1321	CLIP-seq
MIRT1080433	hsa-miR-3162-5p	CLIP-seq
MIRT1080434	hsa-miR-3198	CLIP-seq
MIRT1080435	hsa-miR-326	CLIP-seq
MIRT1080436	hsa-miR-330-5p	CLIP-seq
MIRT1080437	hsa-miR-3614-3p	CLIP-seq
MIRT1080438	hsa-miR-3617	CLIP-seq
MIRT1080439	hsa-miR-4294	CLIP-seq
MIRT1080440	hsa-miR-4309	CLIP-seq
MIRT1080441	hsa-miR-4739	CLIP-seq
MIRT1080442	hsa-miR-4756-5p	CLIP-seq
MIRT1080443	hsa-miR-516b	CLIP-seq
MIRT1080444	hsa-miR-641	CLIP-seq
MIRT1080445	hsa-miR-942	CLIP-seq
MIRT1550397	hsa-miR-1224-3p	CLIP-seq
MIRT1550398	hsa-miR-1237	CLIP-seq
MIRT1550399	hsa-miR-3652	CLIP-seq
MIRT1550400	hsa-miR-4430	CLIP-seq
MIRT1550401	hsa-miR-4505	CLIP-seq
MIRT1550402	hsa-miR-4539	CLIP-seq
MIRT1550403	hsa-miR-647	CLIP-seq
MIRT2251865	hsa-miR-944	CLIP-seq

Show/Hide all(98)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000149	Function	SNARE binding	IEA
GO:0001508	Process	Action potential	IBA
GO:0001508	Process	Action potential	IDA	19223394
GO:0001508	Process	Action potential	IEA
GO:0005216	Function	Monoatomic ion channel activity	IEA
GO:0005249	Function	Voltage-gated potassium channel activity	IEA
GO:0005249	Function	Voltage-gated potassium channel activity	IMP	39469306
GO:0005251	Function	Delayed rectifier potassium channel activity	IDA	1283219, 8081723, 10484328, 11852086, 19074135, 19223394
GO:0005251	Function	Delayed rectifier potassium channel activity	IEA
GO:0005251	Function	Delayed rectifier potassium channel activity	ISS
GO:0005267	Function	Potassium channel activity	IEA
GO:0005515	Function	Protein binding	IPI	10484328, 11852086, 33124732, 34535971
GO:0005886	Component	Plasma membrane	IDA	19223394
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006813	Process	Potassium ion transport	IEA
GO:0006813	Process	Potassium ion transport	IEA
GO:0006887	Process	Exocytosis	IEA
GO:0006904	Process	Vesicle docking involved in exocytosis	IEA
GO:0006904	Process	Vesicle docking involved in exocytosis	ISS
GO:0007215	Process	Glutamate receptor signaling pathway	IEA
GO:0007215	Process	Glutamate receptor signaling pathway	ISS
GO:0008076	Component	Voltage-gated potassium channel complex	IBA
GO:0008076	Component	Voltage-gated potassium channel complex	IDA	19074135, 19223394
GO:0008076	Component	Voltage-gated potassium channel complex	IEA
GO:0008076	Component	Voltage-gated potassium channel complex	ISS
GO:0009986	Component	Cell surface	IEA
GO:0010701	Process	Positive regulation of norepinephrine secretion	IEA
GO:0010701	Process	Positive regulation of norepinephrine secretion	ISS
GO:0015271	Function	Outward rectifier potassium channel activity	IEA
GO:0015459	Function	Potassium channel regulator activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IEA
GO:0016328	Component	Lateral plasma membrane	IEA
GO:0030424	Component	Axon	IBA
GO:0030424	Component	Axon	IEA
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	ISS
GO:0031669	Process	Cellular response to nutrient levels	IEA
GO:0031669	Process	Cellular response to nutrient levels	ISS
GO:0032590	Component	Dendrite membrane	IBA
GO:0032590	Component	Dendrite membrane	IEA
GO:0032809	Component	Neuronal cell body membrane	IBA
GO:0032809	Component	Neuronal cell body membrane	IEA
GO:0032809	Component	Neuronal cell body membrane	ISS
GO:0033605	Process	Positive regulation of catecholamine secretion	IEA
GO:0033605	Process	Positive regulation of catecholamine secretion	ISS
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034702	Component	Monoatomic ion channel complex	IEA
GO:0042383	Component	Sarcolemma	IEA
GO:0042593	Process	Glucose homeostasis	IEA
GO:0042593	Process	Glucose homeostasis	ISS
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0043025	Component	Neuronal cell body	IEA
GO:0043204	Component	Perikaryon	IEA
GO:0043204	Component	Perikaryon	ISS
GO:0044325	Function	Transmembrane transporter binding	IEA
GO:0044325	Function	Transmembrane transporter binding	IPI	19074135
GO:0045163	Process	Clustering of voltage-gated potassium channels	IEA
GO:0045202	Component	Synapse	IEA
GO:0045211	Component	Postsynaptic membrane	IBA
GO:0045211	Component	Postsynaptic membrane	IEA
GO:0045956	Process	Positive regulation of calcium ion-dependent exocytosis	IEA
GO:0045956	Process	Positive regulation of calcium ion-dependent exocytosis	ISS
GO:0046676	Process	Negative regulation of insulin secretion	IEA
GO:0046676	Process	Negative regulation of insulin secretion	ISS
GO:0046982	Function	Protein heterodimerization activity	IEA
GO:0046982	Function	Protein heterodimerization activity	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048678	Process	Response to axon injury	IEA
GO:0051260	Process	Protein homooligomerization	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:0071277	Process	Cellular response to calcium ion	IEA
GO:0071333	Process	Cellular response to glucose stimulus	IEA
GO:0071333	Process	Cellular response to glucose stimulus	ISS
GO:0071805	Process	Potassium ion transmembrane transport	IBA
GO:0071805	Process	Potassium ion transmembrane transport	IDA	19074135, 19223394
GO:0071805	Process	Potassium ion transmembrane transport	IEA
GO:0071805	Process	Potassium ion transmembrane transport	ISS
GO:0072659	Process	Protein localization to plasma membrane	IEA
GO:0072659	Process	Protein localization to plasma membrane	ISS
GO:0090314	Process	Positive regulation of protein targeting to membrane	IDA	19074135
GO:0090314	Process	Positive regulation of protein targeting to membrane	IEA
GO:0090314	Process	Positive regulation of protein targeting to membrane	ISS
GO:0097623	Process	Potassium ion export across plasma membrane	IEA
GO:0098900	Process	Regulation of action potential	IEA
GO:0098900	Process	Regulation of action potential	ISS
GO:0098981	Component	Cholinergic synapse	IEA
GO:0099634	Component	Postsynaptic specialization membrane	IEA
GO:1900454	Process	Positive regulation of long-term synaptic depression	IEA
GO:1900454	Process	Positive regulation of long-term synaptic depression	ISS
GO:1902065	Process	Response to L-glutamate	IEA
GO:1990635	Component	Proximal dendrite	IEA
GO:2000671	Process	Regulation of motor neuron apoptotic process	IEA
GO:2000671	Process	Regulation of motor neuron apoptotic process	ISS

MIM	HGNC	e!Ensembl
600397	6231	ENSG00000158445

Protein

UniProt ID

Q14721

Protein name

Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)

Protein function

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repola

PDB

7RE5 , 7SPD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02214	BTB_2	33 → 132	BTB/POZ domain	Domain
PF00520	Ion_trans	188 → 424	Ion transport protein	Family
PF03521	Kv2channel	467 → 619	Kv2 voltage-gated K+ channel	Family
PF03521	Kv2channel	637 → 685	Kv2 voltage-gated K+ channel	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in neocortical pyramidal cells (PubMed:24477962). Expressed in pancreatic beta cells (at protein level) (PubMed:12403834, PubMed:14988243). Expressed in brain, heart, lung, liver, colon, kidney and adrenal gland (PubMed:19074

Sequence

MPAGMTKHGSRSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKL
RDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELD
YWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLE
KPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWF
TMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFR
IMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTK
FKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFY
KEQKRQEKAIKRREALERAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGENMGKKDKVQD
NHLSPNKWKWTKRTLSETSSSKSFETKEQGSPEKARSSSSPQHLNVQQLEDMYNKMAKTQ
SQPILNTKESAAQSKPKEELEMESIPSPVAPLPTRTEGVIDMRSMSSIDSFISCATDFPE
ATRFSHSPLTSLPSKTGGSTAPEVGWRGALGASGGRFVEANPSPDASQHSSFFIESPKSS
MKTNNPLKLRALKVNFMEGDPSPLLPVLGMYHDPLRNRGSAAAAVAGLECATLLDKAVLS
PESSIYTTASAKTPPRSPEKHTAIAFNFEAGVHQYIDADTDDEGQLLYSVDSSPPKSLPG
STSPKFSTGTRSEKNHFESSPLPTSPKFLRQNCIYSTEALTGKGPSGQEKCKLENHISPD
VRVLPGGGAHGSTRDQSI

Sequence length

858

Interactions

View interactions

	Reactome
			Voltage gated Potassium channels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

Show/Hide Causal Diseases (4)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Developmental And Epileptic Encephalopathy	Developmental and epileptic encephalopathy, 26	rs587777850, rs1601071085, rs1057518621, rs1601071747, rs1555889127, rs1060499592, rs1601072041, rs1555889162, rs1569017015, rs1569017205, rs1555889103, rs1064794764, rs1601070652, rs959316981, rs1555889084 View all (9 more)	N/A
Epileptic encephalopathy	epileptic encephalopathy	rs1569017015, rs1569017205, rs1179351306, rs1569017045, rs1569017257, rs959316981, rs1569017073, rs1555889130, rs1569017337, rs1555889108, rs1555889090, rs1555889162, rs1569017143, rs1555889127, rs1568658507, rs1569017148 View all (1 more)	N/A
Epileptic Encephalopathy	early infantile epileptic encephalopathy with suppression bursts	rs1060499592, rs1555889127	N/A
Mental retardation	intellectual disability	rs1569017160, rs1555889127, rs1569016820, rs1601071971, rs1569017025, rs959316981, rs1555889130, rs781663444	N/A

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Atrial Fibrillation	Atrial fibrillation	N/A	N/A	GWAS
Bipolar Disorder	Bipolar I disorder, Bipolar disorder	N/A	N/A	GWAS
Neurodevelopmental Disorders	complex neurodevelopmental disorder	N/A	N/A	GenCC
Neuroticism	Neuroticism	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (42)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Autistic Disorder	Associate	32954514
Brain Diseases	Associate	26477325, 33607466
Bruxism	Associate	29322350
Carcinoma Renal Cell	Associate	28607108
Cognition Disorders	Associate	30958317
Colorectal Neoplasms	Associate	32484056, 33172410, 33267786
Developmental Disabilities	Associate	26477325, 28806457, 32954514
Diabetes Gestational	Associate	29352517
Diabetes Gestational	Stimulate	29352517
Diabetes Mellitus	Associate	28607108
Diabetes Mellitus Type 2	Associate	23431371, 28607108, 31085831
Epilepsy	Associate	31653223, 32954514
Epilepsy Benign Neonatal	Associate	26477325
Epileptic Encephalopathy Early Infantile 3	Associate	32853554, 32954514, 34181986
Gastrointestinal Neoplasms	Associate	33267786
Genetic Diseases Inborn	Associate	28806457
Glioma	Associate	28144039
Hypertension Pulmonary	Associate	31248429
Hypertensive Retinopathy	Associate	23077521
Hypertrophy Left Ventricular	Associate	19454037
Hypoxia	Inhibit	36651941
Hypoxia Brain	Associate	36651941
Infantile Epileptic Dyskinetic Encephalopathy	Associate	32954514
Inflammation	Associate	33267786
Insulin Resistance	Associate	26377690, 29352517
Intellectual Disability	Associate	32954514
Mental Disorders	Associate	28806457
Metabolic Syndrome	Associate	26377690
Motor Skills Disorders	Associate	29322350
Neoplasms	Inhibit	28144039
Neoplasms	Associate	31248429, 32484056, 33172410, 33267786
Prostatic Neoplasms	Associate	33407994
Psychomotor Disorders	Associate	26477325
Rectal Neoplasms	Associate	33172410
Retinal Cone Dystrophy 3A	Associate	34535971
Rett Syndrome	Associate	29322350
Seizures	Associate	26477325, 28806457
Signs and Symptoms Digestive	Associate	34181986
Spasm	Associate	28806457
Spasms Infantile	Associate	31394400
Stomach Neoplasms	Associate	33267786
Ventricular Dysfunction Left	Associate	19454037

KCNB1 (potassium voltage-gated channel subfamily B member 1)