Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	374354
Gene name Gene Name - the full gene name approved by the HGNC.	NHL repeat containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NHLRC2
Synonyms (NCBI Gene) Gene synonyms aliases	FINCA
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q25.3

Show/Hide all(2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs201701259	G>T	Pathogenic	Coding sequence variant, missense variant
rs757267294	AG>-	Pathogenic	Coding sequence variant, frameshift variant

Show/Hide all(635)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016448	hsa-miR-193b-3p	Microarray	20304954
MIRT041811	hsa-miR-484	CLASH	23622248
MIRT701435	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT701434	hsa-miR-4500	HITS-CLIP	23313552
MIRT701433	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT701432	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT701431	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT701430	hsa-miR-4458	HITS-CLIP	23313552
MIRT701429	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT701428	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT701427	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT701426	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT701425	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT701424	hsa-miR-590-3p	HITS-CLIP	23313552
MIRT701423	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT701422	hsa-miR-202-3p	HITS-CLIP	23313552
MIRT701421	hsa-miR-4775	HITS-CLIP	23313552
MIRT701420	hsa-miR-302f	HITS-CLIP	23313552
MIRT701419	hsa-miR-6768-5p	HITS-CLIP	23313552
MIRT701418	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT701417	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687491	hsa-miR-548ac	HITS-CLIP	23313552
MIRT687490	hsa-miR-548bb-3p	HITS-CLIP	23313552
MIRT687489	hsa-miR-548d-3p	HITS-CLIP	23313552
MIRT687488	hsa-miR-548h-3p	HITS-CLIP	23313552
MIRT687487	hsa-miR-548z	HITS-CLIP	23313552
MIRT687486	hsa-miR-548ae-3p	HITS-CLIP	23313552
MIRT687485	hsa-miR-548ah-3p	HITS-CLIP	23313552
MIRT687484	hsa-miR-548aj-3p	HITS-CLIP	23313552
MIRT687483	hsa-miR-548am-3p	HITS-CLIP	23313552
MIRT687482	hsa-miR-548aq-3p	HITS-CLIP	23313552
MIRT687481	hsa-miR-548j-3p	HITS-CLIP	23313552
MIRT687480	hsa-miR-548x-3p	HITS-CLIP	23313552
MIRT687479	hsa-miR-6732-3p	HITS-CLIP	23313552
MIRT687478	hsa-miR-339-5p	HITS-CLIP	23313552
MIRT687477	hsa-miR-4421	HITS-CLIP	23313552
MIRT687476	hsa-miR-5699-3p	HITS-CLIP	23313552
MIRT687475	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT687474	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT687473	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT645982	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT645981	hsa-miR-6776-3p	HITS-CLIP	23824327
MIRT645980	hsa-miR-6796-3p	HITS-CLIP	23824327
MIRT645979	hsa-miR-4418	HITS-CLIP	23824327
MIRT645978	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT645977	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT645976	hsa-miR-217	HITS-CLIP	23824327
MIRT645975	hsa-miR-6807-3p	HITS-CLIP	23824327
MIRT645974	hsa-miR-8063	HITS-CLIP	23824327
MIRT645973	hsa-miR-548aj-5p	HITS-CLIP	23824327
MIRT645972	hsa-miR-548f-5p	HITS-CLIP	23824327
MIRT645971	hsa-miR-548g-5p	HITS-CLIP	23824327
MIRT645970	hsa-miR-548x-5p	HITS-CLIP	23824327
MIRT645969	hsa-miR-1468-3p	HITS-CLIP	23824327
MIRT176743	hsa-miR-548aw	HITS-CLIP	23824327
MIRT635393	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT635392	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT635391	hsa-miR-940	HITS-CLIP	23824327
MIRT635390	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT176698	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT635389	hsa-miR-1827	HITS-CLIP	23824327
MIRT635388	hsa-miR-6878-5p	HITS-CLIP	23824327
MIRT635387	hsa-miR-6731-5p	HITS-CLIP	23824327
MIRT635386	hsa-miR-8085	HITS-CLIP	23824327
MIRT635385	hsa-miR-7977	HITS-CLIP	23824327
MIRT176695	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT176694	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT176703	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT635384	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT635383	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT635382	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT635381	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT635380	hsa-miR-3689c	HITS-CLIP	23824327
MIRT635379	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT635378	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT635377	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT635376	hsa-miR-3122	HITS-CLIP	23824327
MIRT635375	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT635374	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT635373	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT535682	hsa-miR-548e-5p	PAR-CLIP	22012620
MIRT535681	hsa-miR-6835-3p	PAR-CLIP	22012620
MIRT535680	hsa-miR-4424	PAR-CLIP	22012620
MIRT535679	hsa-miR-374c-5p	PAR-CLIP	22012620
MIRT535678	hsa-miR-655-3p	PAR-CLIP	22012620
MIRT535677	hsa-miR-633	PAR-CLIP	22012620
MIRT701435	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT701434	hsa-miR-4500	HITS-CLIP	23313552
MIRT701433	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT701432	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT701431	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT701430	hsa-miR-4458	HITS-CLIP	23313552
MIRT701429	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT701428	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT701427	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT701426	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT701425	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT701424	hsa-miR-590-3p	HITS-CLIP	23313552
MIRT701423	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT701422	hsa-miR-202-3p	HITS-CLIP	23313552
MIRT701421	hsa-miR-4775	HITS-CLIP	23313552
MIRT701420	hsa-miR-302f	HITS-CLIP	23313552
MIRT701419	hsa-miR-6768-5p	HITS-CLIP	23313552
MIRT701418	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT701417	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT687491	hsa-miR-548ac	HITS-CLIP	23313552
MIRT687490	hsa-miR-548bb-3p	HITS-CLIP	23313552
MIRT687489	hsa-miR-548d-3p	HITS-CLIP	23313552
MIRT687488	hsa-miR-548h-3p	HITS-CLIP	23313552
MIRT687487	hsa-miR-548z	HITS-CLIP	23313552
MIRT687486	hsa-miR-548ae-3p	HITS-CLIP	23313552
MIRT687485	hsa-miR-548ah-3p	HITS-CLIP	23313552
MIRT687484	hsa-miR-548aj-3p	HITS-CLIP	23313552
MIRT687483	hsa-miR-548am-3p	HITS-CLIP	23313552
MIRT687482	hsa-miR-548aq-3p	HITS-CLIP	23313552
MIRT687481	hsa-miR-548j-3p	HITS-CLIP	23313552
MIRT687480	hsa-miR-548x-3p	HITS-CLIP	23313552
MIRT687479	hsa-miR-6732-3p	HITS-CLIP	23313552
MIRT687478	hsa-miR-339-5p	HITS-CLIP	23313552
MIRT687477	hsa-miR-4421	HITS-CLIP	23313552
MIRT687476	hsa-miR-5699-3p	HITS-CLIP	23313552
MIRT687475	hsa-miR-6895-3p	HITS-CLIP	23313552
MIRT687474	hsa-miR-593-3p	HITS-CLIP	23313552
MIRT687473	hsa-miR-6818-3p	HITS-CLIP	23313552
MIRT645982	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT645981	hsa-miR-6776-3p	HITS-CLIP	23824327
MIRT645980	hsa-miR-6796-3p	HITS-CLIP	23824327
MIRT645979	hsa-miR-4418	HITS-CLIP	23824327
MIRT645978	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT645977	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT645976	hsa-miR-217	HITS-CLIP	23824327
MIRT645975	hsa-miR-6807-3p	HITS-CLIP	23824327
MIRT645974	hsa-miR-8063	HITS-CLIP	23824327
MIRT645973	hsa-miR-548aj-5p	HITS-CLIP	23824327
MIRT645972	hsa-miR-548f-5p	HITS-CLIP	23824327
MIRT645971	hsa-miR-548g-5p	HITS-CLIP	23824327
MIRT645970	hsa-miR-548x-5p	HITS-CLIP	23824327
MIRT645969	hsa-miR-1468-3p	HITS-CLIP	23824327
MIRT176743	hsa-miR-548aw	HITS-CLIP	23824327
MIRT635393	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT635392	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT635391	hsa-miR-940	HITS-CLIP	23824327
MIRT635390	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT176698	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT635389	hsa-miR-1827	HITS-CLIP	23824327
MIRT635388	hsa-miR-6878-5p	HITS-CLIP	23824327
MIRT635387	hsa-miR-6731-5p	HITS-CLIP	23824327
MIRT635386	hsa-miR-8085	HITS-CLIP	23824327
MIRT635385	hsa-miR-7977	HITS-CLIP	23824327
MIRT176695	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT176694	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT176703	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT635384	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT635383	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT635382	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT635381	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT635380	hsa-miR-3689c	HITS-CLIP	23824327
MIRT635379	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT635378	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT635377	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT635376	hsa-miR-3122	HITS-CLIP	23824327
MIRT635375	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT635374	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT635373	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT535682	hsa-miR-548e-5p	PAR-CLIP	22012620
MIRT535681	hsa-miR-6835-3p	PAR-CLIP	22012620
MIRT535680	hsa-miR-4424	PAR-CLIP	22012620
MIRT535679	hsa-miR-374c-5p	PAR-CLIP	22012620
MIRT535678	hsa-miR-655-3p	PAR-CLIP	22012620
MIRT535677	hsa-miR-633	PAR-CLIP	22012620
MIRT1184354	hsa-let-7a	CLIP-seq
MIRT1184355	hsa-let-7b	CLIP-seq
MIRT1184356	hsa-let-7c	CLIP-seq
MIRT1184357	hsa-let-7d	CLIP-seq
MIRT1184358	hsa-let-7e	CLIP-seq
MIRT1184359	hsa-let-7f	CLIP-seq
MIRT1184360	hsa-let-7g	CLIP-seq
MIRT1184361	hsa-let-7i	CLIP-seq
MIRT1184362	hsa-miR-103a	CLIP-seq
MIRT1184363	hsa-miR-107	CLIP-seq
MIRT1184364	hsa-miR-1178	CLIP-seq
MIRT1184365	hsa-miR-1183	CLIP-seq
MIRT1184366	hsa-miR-1208	CLIP-seq
MIRT1184367	hsa-miR-1227	CLIP-seq
MIRT1184368	hsa-miR-1279	CLIP-seq
MIRT1184369	hsa-miR-1292	CLIP-seq
MIRT1184370	hsa-miR-1294	CLIP-seq
MIRT1184371	hsa-miR-1297	CLIP-seq
MIRT1184372	hsa-miR-137	CLIP-seq
MIRT1184373	hsa-miR-142-3p	CLIP-seq
MIRT1184374	hsa-miR-15a	CLIP-seq
MIRT1184375	hsa-miR-15b	CLIP-seq
MIRT1184376	hsa-miR-16	CLIP-seq
MIRT1184377	hsa-miR-181a	CLIP-seq
MIRT1184378	hsa-miR-181b	CLIP-seq
MIRT1184379	hsa-miR-181c	CLIP-seq
MIRT1184380	hsa-miR-181d	CLIP-seq
MIRT1184381	hsa-miR-195	CLIP-seq
MIRT1184382	hsa-miR-200b	CLIP-seq
MIRT1184383	hsa-miR-200c	CLIP-seq
MIRT1184384	hsa-miR-2392	CLIP-seq
MIRT1184385	hsa-miR-25	CLIP-seq
MIRT1184386	hsa-miR-26a	CLIP-seq
MIRT1184387	hsa-miR-26b	CLIP-seq
MIRT1184388	hsa-miR-300	CLIP-seq
MIRT1184389	hsa-miR-3121-3p	CLIP-seq
MIRT1184390	hsa-miR-3121-5p	CLIP-seq
MIRT1184391	hsa-miR-3126-3p	CLIP-seq
MIRT1184392	hsa-miR-3163	CLIP-seq
MIRT1184393	hsa-miR-3164	CLIP-seq
MIRT1184394	hsa-miR-3173-3p	CLIP-seq
MIRT1184395	hsa-miR-32	CLIP-seq
MIRT1184396	hsa-miR-3202	CLIP-seq
MIRT1184397	hsa-miR-338-5p	CLIP-seq
MIRT1184398	hsa-miR-33a	CLIP-seq
MIRT1184399	hsa-miR-33b	CLIP-seq
MIRT1184400	hsa-miR-3613-3p	CLIP-seq
MIRT1184401	hsa-miR-361-5p	CLIP-seq
MIRT1184402	hsa-miR-363	CLIP-seq
MIRT1184403	hsa-miR-367	CLIP-seq
MIRT1184404	hsa-miR-369-3p	CLIP-seq
MIRT1184405	hsa-miR-371-5p	CLIP-seq
MIRT1184406	hsa-miR-371b-5p	CLIP-seq
MIRT1184407	hsa-miR-374a	CLIP-seq
MIRT1184408	hsa-miR-374b	CLIP-seq
MIRT1184409	hsa-miR-381	CLIP-seq
MIRT1184410	hsa-miR-3927	CLIP-seq
MIRT1184411	hsa-miR-3937	CLIP-seq
MIRT1184412	hsa-miR-3941	CLIP-seq
MIRT1184413	hsa-miR-424	CLIP-seq
MIRT1184414	hsa-miR-4252	CLIP-seq
MIRT1184415	hsa-miR-4262	CLIP-seq
MIRT1184416	hsa-miR-4264	CLIP-seq
MIRT1184417	hsa-miR-4272	CLIP-seq
MIRT1184418	hsa-miR-429	CLIP-seq
MIRT1184419	hsa-miR-4290	CLIP-seq
MIRT1184420	hsa-miR-4420	CLIP-seq
MIRT1184421	hsa-miR-4428	CLIP-seq
MIRT1184422	hsa-miR-4451	CLIP-seq
MIRT1184423	hsa-miR-4459	CLIP-seq
MIRT1184424	hsa-miR-4465	CLIP-seq
MIRT1184425	hsa-miR-4471	CLIP-seq
MIRT1184426	hsa-miR-4474-5p	CLIP-seq
MIRT1184427	hsa-miR-4490	CLIP-seq
MIRT1184428	hsa-miR-452	CLIP-seq
MIRT1184429	hsa-miR-4524	CLIP-seq
MIRT1184430	hsa-miR-4528	CLIP-seq
MIRT1184431	hsa-miR-4633-5p	CLIP-seq
MIRT1184432	hsa-miR-4643	CLIP-seq
MIRT1184433	hsa-miR-4645-3p	CLIP-seq
MIRT1184434	hsa-miR-466	CLIP-seq
MIRT1184435	hsa-miR-4666-3p	CLIP-seq
MIRT1184436	hsa-miR-4672	CLIP-seq
MIRT1184437	hsa-miR-4676-3p	CLIP-seq
MIRT1184438	hsa-miR-4684-5p	CLIP-seq
MIRT1184439	hsa-miR-4698	CLIP-seq
MIRT1184440	hsa-miR-4704-5p	CLIP-seq
MIRT1184441	hsa-miR-4747-5p	CLIP-seq
MIRT1184442	hsa-miR-4774-5p	CLIP-seq
MIRT1184443	hsa-miR-4789-3p	CLIP-seq
MIRT1184444	hsa-miR-4789-5p	CLIP-seq
MIRT1184445	hsa-miR-4795-3p	CLIP-seq
MIRT1184446	hsa-miR-4797-3p	CLIP-seq
MIRT1184447	hsa-miR-497	CLIP-seq
MIRT1184448	hsa-miR-498	CLIP-seq
MIRT1184449	hsa-miR-503	CLIP-seq
MIRT1184450	hsa-miR-5095	CLIP-seq
MIRT1184451	hsa-miR-5096	CLIP-seq
MIRT1184452	hsa-miR-518a-5p	CLIP-seq
MIRT1184453	hsa-miR-527	CLIP-seq
MIRT1184454	hsa-miR-548c-3p	CLIP-seq
MIRT1184455	hsa-miR-548l	CLIP-seq
MIRT1184456	hsa-miR-548n	CLIP-seq
MIRT1184457	hsa-miR-581	CLIP-seq
MIRT1184458	hsa-miR-582-5p	CLIP-seq
MIRT1184459	hsa-miR-595	CLIP-seq
MIRT1184460	hsa-miR-622	CLIP-seq
MIRT1184461	hsa-miR-630	CLIP-seq
MIRT1184462	hsa-miR-646	CLIP-seq
MIRT1184463	hsa-miR-648	CLIP-seq
MIRT1184464	hsa-miR-656	CLIP-seq
MIRT1184465	hsa-miR-664	CLIP-seq
MIRT1184466	hsa-miR-665	CLIP-seq
MIRT1184467	hsa-miR-668	CLIP-seq
MIRT1184468	hsa-miR-92a	CLIP-seq
MIRT1184469	hsa-miR-92b	CLIP-seq
MIRT1184470	hsa-miR-934	CLIP-seq
MIRT1184471	hsa-miR-935	CLIP-seq
MIRT1184472	hsa-miR-98	CLIP-seq
MIRT1184354	hsa-let-7a	CLIP-seq
MIRT1184355	hsa-let-7b	CLIP-seq
MIRT1184356	hsa-let-7c	CLIP-seq
MIRT1184357	hsa-let-7d	CLIP-seq
MIRT1184358	hsa-let-7e	CLIP-seq
MIRT1184359	hsa-let-7f	CLIP-seq
MIRT1184360	hsa-let-7g	CLIP-seq
MIRT1184361	hsa-let-7i	CLIP-seq
MIRT1184366	hsa-miR-1208	CLIP-seq
MIRT1551752	hsa-miR-3157-5p	CLIP-seq
MIRT1551753	hsa-miR-330-3p	CLIP-seq
MIRT1184404	hsa-miR-369-3p	CLIP-seq
MIRT1184407	hsa-miR-374a	CLIP-seq
MIRT1184408	hsa-miR-374b	CLIP-seq
MIRT1184410	hsa-miR-3927	CLIP-seq
MIRT1184422	hsa-miR-4451	CLIP-seq
MIRT1184423	hsa-miR-4459	CLIP-seq
MIRT1551754	hsa-miR-4691-3p	CLIP-seq
MIRT1184466	hsa-miR-665	CLIP-seq
MIRT1184472	hsa-miR-98	CLIP-seq
MIRT1184362	hsa-miR-103a	CLIP-seq
MIRT1184363	hsa-miR-107	CLIP-seq
MIRT1184365	hsa-miR-1183	CLIP-seq
MIRT1184366	hsa-miR-1208	CLIP-seq
MIRT1184367	hsa-miR-1227	CLIP-seq
MIRT2053451	hsa-miR-1231	CLIP-seq
MIRT2053452	hsa-miR-124	CLIP-seq
MIRT1184368	hsa-miR-1279	CLIP-seq
MIRT1184370	hsa-miR-1294	CLIP-seq
MIRT1184371	hsa-miR-1297	CLIP-seq
MIRT2053453	hsa-miR-1303	CLIP-seq
MIRT1184372	hsa-miR-137	CLIP-seq
MIRT2053454	hsa-miR-141	CLIP-seq
MIRT1184373	hsa-miR-142-3p	CLIP-seq
MIRT1184374	hsa-miR-15a	CLIP-seq
MIRT1184375	hsa-miR-15b	CLIP-seq
MIRT1184376	hsa-miR-16	CLIP-seq
MIRT2053455	hsa-miR-1910	CLIP-seq
MIRT1184381	hsa-miR-195	CLIP-seq
MIRT2053456	hsa-miR-200a	CLIP-seq
MIRT2053457	hsa-miR-205	CLIP-seq
MIRT2053458	hsa-miR-2054	CLIP-seq
MIRT2053459	hsa-miR-2116	CLIP-seq
MIRT1184384	hsa-miR-2392	CLIP-seq
MIRT1184385	hsa-miR-25	CLIP-seq
MIRT2053460	hsa-miR-2681	CLIP-seq
MIRT1184386	hsa-miR-26a	CLIP-seq
MIRT1184387	hsa-miR-26b	CLIP-seq
MIRT2053461	hsa-miR-3074-3p	CLIP-seq
MIRT1184390	hsa-miR-3121-5p	CLIP-seq
MIRT2053462	hsa-miR-3124-3p	CLIP-seq
MIRT1184393	hsa-miR-3164	CLIP-seq
MIRT1184395	hsa-miR-32	CLIP-seq
MIRT1184396	hsa-miR-3202	CLIP-seq
MIRT1184397	hsa-miR-338-5p	CLIP-seq
MIRT1184398	hsa-miR-33a	CLIP-seq
MIRT1184399	hsa-miR-33b	CLIP-seq
MIRT2053463	hsa-miR-3545-3p	CLIP-seq
MIRT1184400	hsa-miR-3613-3p	CLIP-seq
MIRT1184401	hsa-miR-361-5p	CLIP-seq
MIRT2053464	hsa-miR-3622a-3p	CLIP-seq
MIRT2053465	hsa-miR-3622b-3p	CLIP-seq
MIRT1184402	hsa-miR-363	CLIP-seq
MIRT1184403	hsa-miR-367	CLIP-seq
MIRT2053466	hsa-miR-3671	CLIP-seq
MIRT2053467	hsa-miR-3682-5p	CLIP-seq
MIRT2053468	hsa-miR-3714	CLIP-seq
MIRT2053469	hsa-miR-3908	CLIP-seq
MIRT2053470	hsa-miR-3910	CLIP-seq
MIRT2053471	hsa-miR-3919	CLIP-seq
MIRT2053472	hsa-miR-3929	CLIP-seq
MIRT1184411	hsa-miR-3937	CLIP-seq
MIRT2053473	hsa-miR-3945	CLIP-seq
MIRT1184413	hsa-miR-424	CLIP-seq
MIRT2053474	hsa-miR-4253	CLIP-seq
MIRT2053475	hsa-miR-4273	CLIP-seq
MIRT2053476	hsa-miR-4282	CLIP-seq
MIRT2053477	hsa-miR-4288	CLIP-seq
MIRT2053478	hsa-miR-433	CLIP-seq
MIRT2053479	hsa-miR-4419b	CLIP-seq
MIRT1184420	hsa-miR-4420	CLIP-seq
MIRT2053480	hsa-miR-4433	CLIP-seq
MIRT1184424	hsa-miR-4465	CLIP-seq
MIRT2053481	hsa-miR-4477b	CLIP-seq
MIRT2053482	hsa-miR-4478	CLIP-seq
MIRT2053483	hsa-miR-4517	CLIP-seq
MIRT1184428	hsa-miR-452	CLIP-seq
MIRT1184429	hsa-miR-4524	CLIP-seq
MIRT1184430	hsa-miR-4528	CLIP-seq
MIRT2053484	hsa-miR-4539	CLIP-seq
MIRT2053485	hsa-miR-455-3p	CLIP-seq
MIRT1184431	hsa-miR-4633-5p	CLIP-seq
MIRT2053486	hsa-miR-4649-3p	CLIP-seq
MIRT2053487	hsa-miR-4670-3p	CLIP-seq
MIRT1184437	hsa-miR-4676-3p	CLIP-seq
MIRT2053488	hsa-miR-4677-5p	CLIP-seq
MIRT1184438	hsa-miR-4684-5p	CLIP-seq
MIRT2053489	hsa-miR-4699-3p	CLIP-seq
MIRT1184440	hsa-miR-4704-5p	CLIP-seq
MIRT2053490	hsa-miR-4728-5p	CLIP-seq
MIRT2053491	hsa-miR-4736	CLIP-seq
MIRT1184441	hsa-miR-4747-5p	CLIP-seq
MIRT2053492	hsa-miR-4756-3p	CLIP-seq
MIRT1184444	hsa-miR-4789-5p	CLIP-seq
MIRT1184445	hsa-miR-4795-3p	CLIP-seq
MIRT2053493	hsa-miR-4796-5p	CLIP-seq
MIRT2053494	hsa-miR-485-5p	CLIP-seq
MIRT2053495	hsa-miR-495	CLIP-seq
MIRT1184447	hsa-miR-497	CLIP-seq
MIRT1184449	hsa-miR-503	CLIP-seq
MIRT2053496	hsa-miR-506	CLIP-seq
MIRT1184450	hsa-miR-5095	CLIP-seq
MIRT1184451	hsa-miR-5096	CLIP-seq
MIRT2053497	hsa-miR-513b	CLIP-seq
MIRT1184452	hsa-miR-518a-5p	CLIP-seq
MIRT2053498	hsa-miR-520a-5p	CLIP-seq
MIRT2053499	hsa-miR-520d-5p	CLIP-seq
MIRT2053500	hsa-miR-524-5p	CLIP-seq
MIRT2053501	hsa-miR-525-5p	CLIP-seq
MIRT1184453	hsa-miR-527	CLIP-seq
MIRT2053502	hsa-miR-532-5p	CLIP-seq
MIRT2053503	hsa-miR-544b	CLIP-seq
MIRT2053504	hsa-miR-561	CLIP-seq
MIRT2053505	hsa-miR-579	CLIP-seq
MIRT1184457	hsa-miR-581	CLIP-seq
MIRT1184458	hsa-miR-582-5p	CLIP-seq
MIRT2053506	hsa-miR-607	CLIP-seq
MIRT1184460	hsa-miR-622	CLIP-seq
MIRT1184461	hsa-miR-630	CLIP-seq
MIRT2053507	hsa-miR-632	CLIP-seq
MIRT1184462	hsa-miR-646	CLIP-seq
MIRT1184463	hsa-miR-648	CLIP-seq
MIRT1184464	hsa-miR-656	CLIP-seq
MIRT1184466	hsa-miR-665	CLIP-seq
MIRT2053508	hsa-miR-890	CLIP-seq
MIRT1184468	hsa-miR-92a	CLIP-seq
MIRT1184469	hsa-miR-92b	CLIP-seq
MIRT1184354	hsa-let-7a	CLIP-seq
MIRT1184355	hsa-let-7b	CLIP-seq
MIRT1184356	hsa-let-7c	CLIP-seq
MIRT1184357	hsa-let-7d	CLIP-seq
MIRT1184358	hsa-let-7e	CLIP-seq
MIRT1184359	hsa-let-7f	CLIP-seq
MIRT1184360	hsa-let-7g	CLIP-seq
MIRT1184361	hsa-let-7i	CLIP-seq
MIRT1184362	hsa-miR-103a	CLIP-seq
MIRT2282666	hsa-miR-105	CLIP-seq
MIRT1184363	hsa-miR-107	CLIP-seq
MIRT1184365	hsa-miR-1183	CLIP-seq
MIRT1184366	hsa-miR-1208	CLIP-seq
MIRT1184367	hsa-miR-1227	CLIP-seq
MIRT2053451	hsa-miR-1231	CLIP-seq
MIRT2053452	hsa-miR-124	CLIP-seq
MIRT1184371	hsa-miR-1297	CLIP-seq
MIRT2053453	hsa-miR-1303	CLIP-seq
MIRT1184372	hsa-miR-137	CLIP-seq
MIRT1184373	hsa-miR-142-3p	CLIP-seq
MIRT1184374	hsa-miR-15a	CLIP-seq
MIRT1184375	hsa-miR-15b	CLIP-seq
MIRT1184376	hsa-miR-16	CLIP-seq
MIRT1184377	hsa-miR-181a	CLIP-seq
MIRT1184378	hsa-miR-181b	CLIP-seq
MIRT1184379	hsa-miR-181c	CLIP-seq
MIRT1184380	hsa-miR-181d	CLIP-seq
MIRT2282667	hsa-miR-190	CLIP-seq
MIRT2282668	hsa-miR-190b	CLIP-seq
MIRT2053455	hsa-miR-1910	CLIP-seq
MIRT1184381	hsa-miR-195	CLIP-seq
MIRT2282669	hsa-miR-216b	CLIP-seq
MIRT1184385	hsa-miR-25	CLIP-seq
MIRT2053460	hsa-miR-2681	CLIP-seq
MIRT1184386	hsa-miR-26a	CLIP-seq
MIRT1184387	hsa-miR-26b	CLIP-seq
MIRT2053461	hsa-miR-3074-3p	CLIP-seq
MIRT1551752	hsa-miR-3157-5p	CLIP-seq
MIRT1184394	hsa-miR-3173-3p	CLIP-seq
MIRT2282670	hsa-miR-3189-5p	CLIP-seq
MIRT1184395	hsa-miR-32	CLIP-seq
MIRT1551753	hsa-miR-330-3p	CLIP-seq
MIRT1184397	hsa-miR-338-5p	CLIP-seq
MIRT2053463	hsa-miR-3545-3p	CLIP-seq
MIRT1184400	hsa-miR-3613-3p	CLIP-seq
MIRT1184401	hsa-miR-361-5p	CLIP-seq
MIRT2053464	hsa-miR-3622a-3p	CLIP-seq
MIRT2053465	hsa-miR-3622b-3p	CLIP-seq
MIRT1184402	hsa-miR-363	CLIP-seq
MIRT1184403	hsa-miR-367	CLIP-seq
MIRT2053467	hsa-miR-3682-5p	CLIP-seq
MIRT1184404	hsa-miR-369-3p	CLIP-seq
MIRT2053468	hsa-miR-3714	CLIP-seq
MIRT1184406	hsa-miR-371b-5p	CLIP-seq
MIRT1184407	hsa-miR-374a	CLIP-seq
MIRT1184408	hsa-miR-374b	CLIP-seq
MIRT2282671	hsa-miR-378g	CLIP-seq
MIRT2282672	hsa-miR-380	CLIP-seq
MIRT2053469	hsa-miR-3908	CLIP-seq
MIRT2053470	hsa-miR-3910	CLIP-seq
MIRT2053471	hsa-miR-3919	CLIP-seq
MIRT1184410	hsa-miR-3927	CLIP-seq
MIRT2053472	hsa-miR-3929	CLIP-seq
MIRT1184411	hsa-miR-3937	CLIP-seq
MIRT1184412	hsa-miR-3941	CLIP-seq
MIRT2053473	hsa-miR-3945	CLIP-seq
MIRT1184413	hsa-miR-424	CLIP-seq
MIRT1184414	hsa-miR-4252	CLIP-seq
MIRT2053474	hsa-miR-4253	CLIP-seq
MIRT1184415	hsa-miR-4262	CLIP-seq
MIRT2053477	hsa-miR-4288	CLIP-seq
MIRT1184419	hsa-miR-4290	CLIP-seq
MIRT2282673	hsa-miR-4323	CLIP-seq
MIRT2053478	hsa-miR-433	CLIP-seq
MIRT2053479	hsa-miR-4419b	CLIP-seq
MIRT1184421	hsa-miR-4428	CLIP-seq
MIRT1184422	hsa-miR-4451	CLIP-seq
MIRT1184423	hsa-miR-4459	CLIP-seq
MIRT1184424	hsa-miR-4465	CLIP-seq
MIRT2053481	hsa-miR-4477b	CLIP-seq
MIRT2053482	hsa-miR-4478	CLIP-seq
MIRT2282674	hsa-miR-4495	CLIP-seq
MIRT2053483	hsa-miR-4517	CLIP-seq
MIRT1184429	hsa-miR-4524	CLIP-seq
MIRT2053484	hsa-miR-4539	CLIP-seq
MIRT2053485	hsa-miR-455-3p	CLIP-seq
MIRT2282675	hsa-miR-4635	CLIP-seq
MIRT1184432	hsa-miR-4643	CLIP-seq
MIRT2053486	hsa-miR-4649-3p	CLIP-seq
MIRT1184434	hsa-miR-466	CLIP-seq
MIRT1184436	hsa-miR-4672	CLIP-seq
MIRT2282676	hsa-miR-4690-3p	CLIP-seq
MIRT1551754	hsa-miR-4691-3p	CLIP-seq
MIRT1184440	hsa-miR-4704-5p	CLIP-seq
MIRT2053490	hsa-miR-4728-5p	CLIP-seq
MIRT2053491	hsa-miR-4736	CLIP-seq
MIRT2053492	hsa-miR-4756-3p	CLIP-seq
MIRT1184443	hsa-miR-4789-3p	CLIP-seq
MIRT1184444	hsa-miR-4789-5p	CLIP-seq
MIRT1184445	hsa-miR-4795-3p	CLIP-seq
MIRT2282677	hsa-miR-4797-5p	CLIP-seq
MIRT2053494	hsa-miR-485-5p	CLIP-seq
MIRT2282678	hsa-miR-488	CLIP-seq
MIRT1184447	hsa-miR-497	CLIP-seq
MIRT1184449	hsa-miR-503	CLIP-seq
MIRT2053496	hsa-miR-506	CLIP-seq
MIRT2282679	hsa-miR-512-5p	CLIP-seq
MIRT1184452	hsa-miR-518a-5p	CLIP-seq
MIRT2053499	hsa-miR-520d-5p	CLIP-seq
MIRT2053500	hsa-miR-524-5p	CLIP-seq
MIRT1184453	hsa-miR-527	CLIP-seq
MIRT1184454	hsa-miR-548c-3p	CLIP-seq
MIRT2282680	hsa-miR-548v	CLIP-seq
MIRT2053504	hsa-miR-561	CLIP-seq
MIRT1184457	hsa-miR-581	CLIP-seq
MIRT1184459	hsa-miR-595	CLIP-seq
MIRT2282681	hsa-miR-599	CLIP-seq
MIRT1184460	hsa-miR-622	CLIP-seq
MIRT1184461	hsa-miR-630	CLIP-seq
MIRT2053507	hsa-miR-632	CLIP-seq
MIRT1184462	hsa-miR-646	CLIP-seq
MIRT1184463	hsa-miR-648	CLIP-seq
MIRT2282682	hsa-miR-661	CLIP-seq
MIRT1184466	hsa-miR-665	CLIP-seq
MIRT1184467	hsa-miR-668	CLIP-seq
MIRT2282683	hsa-miR-888	CLIP-seq
MIRT2282684	hsa-miR-889	CLIP-seq
MIRT2053508	hsa-miR-890	CLIP-seq
MIRT1184468	hsa-miR-92a	CLIP-seq
MIRT1184469	hsa-miR-92b	CLIP-seq
MIRT1184472	hsa-miR-98	CLIP-seq
MIRT1184366	hsa-miR-1208	CLIP-seq
MIRT1184390	hsa-miR-3121-5p	CLIP-seq
MIRT1184396	hsa-miR-3202	CLIP-seq
MIRT1184398	hsa-miR-33a	CLIP-seq
MIRT1184399	hsa-miR-33b	CLIP-seq
MIRT2053464	hsa-miR-3622a-3p	CLIP-seq
MIRT2053465	hsa-miR-3622b-3p	CLIP-seq
MIRT1184411	hsa-miR-3937	CLIP-seq
MIRT1184420	hsa-miR-4420	CLIP-seq
MIRT1184428	hsa-miR-452	CLIP-seq
MIRT2053486	hsa-miR-4649-3p	CLIP-seq
MIRT1184437	hsa-miR-4676-3p	CLIP-seq
MIRT1184440	hsa-miR-4704-5p	CLIP-seq
MIRT1184441	hsa-miR-4747-5p	CLIP-seq
MIRT1184450	hsa-miR-5095	CLIP-seq
MIRT1184451	hsa-miR-5096	CLIP-seq
MIRT2053503	hsa-miR-544b	CLIP-seq
MIRT1184464	hsa-miR-656	CLIP-seq
MIRT2053472	hsa-miR-3929	CLIP-seq
MIRT2053479	hsa-miR-4419b	CLIP-seq
MIRT2053482	hsa-miR-4478	CLIP-seq
MIRT2053490	hsa-miR-4728-5p	CLIP-seq
MIRT2053494	hsa-miR-485-5p	CLIP-seq
MIRT2282681	hsa-miR-599	CLIP-seq
MIRT2053508	hsa-miR-890	CLIP-seq
MIRT2282681	hsa-miR-599	CLIP-seq
MIRT2580656	hsa-miR-10a	CLIP-seq
MIRT2580657	hsa-miR-10b	CLIP-seq
MIRT2580658	hsa-miR-1285	CLIP-seq
MIRT2053459	hsa-miR-2116	CLIP-seq
MIRT2580659	hsa-miR-3187-5p	CLIP-seq
MIRT2580660	hsa-miR-323-5p	CLIP-seq
MIRT2580661	hsa-miR-34c-3p	CLIP-seq
MIRT1184400	hsa-miR-3613-3p	CLIP-seq
MIRT2580662	hsa-miR-3622b-5p	CLIP-seq
MIRT2580663	hsa-miR-3654	CLIP-seq
MIRT2053472	hsa-miR-3929	CLIP-seq
MIRT2053473	hsa-miR-3945	CLIP-seq
MIRT2053474	hsa-miR-4253	CLIP-seq
MIRT2053475	hsa-miR-4273	CLIP-seq
MIRT2053479	hsa-miR-4419b	CLIP-seq
MIRT2053482	hsa-miR-4478	CLIP-seq
MIRT2580664	hsa-miR-4638-3p	CLIP-seq
MIRT2053486	hsa-miR-4649-3p	CLIP-seq
MIRT2053488	hsa-miR-4677-5p	CLIP-seq
MIRT1184438	hsa-miR-4684-5p	CLIP-seq
MIRT1184440	hsa-miR-4704-5p	CLIP-seq
MIRT2053490	hsa-miR-4728-5p	CLIP-seq
MIRT2053494	hsa-miR-485-5p	CLIP-seq
MIRT2580665	hsa-miR-548ae	CLIP-seq
MIRT2580666	hsa-miR-548aj	CLIP-seq
MIRT2580667	hsa-miR-548am	CLIP-seq
MIRT2580668	hsa-miR-548x	CLIP-seq
MIRT2580669	hsa-miR-593	CLIP-seq
MIRT2282681	hsa-miR-599	CLIP-seq
MIRT2580670	hsa-miR-612	CLIP-seq
MIRT2580671	hsa-miR-876-3p	CLIP-seq
MIRT2053508	hsa-miR-890	CLIP-seq
MIRT2580656	hsa-miR-10a	CLIP-seq
MIRT2580657	hsa-miR-10b	CLIP-seq
MIRT2686298	hsa-miR-1228	CLIP-seq
MIRT2580658	hsa-miR-1285	CLIP-seq
MIRT2580659	hsa-miR-3187-5p	CLIP-seq
MIRT2580660	hsa-miR-323-5p	CLIP-seq
MIRT1184400	hsa-miR-3613-3p	CLIP-seq
MIRT2580662	hsa-miR-3622b-5p	CLIP-seq
MIRT2053473	hsa-miR-3945	CLIP-seq
MIRT2053474	hsa-miR-4253	CLIP-seq
MIRT2053486	hsa-miR-4649-3p	CLIP-seq
MIRT1184438	hsa-miR-4684-5p	CLIP-seq
MIRT2580665	hsa-miR-548ae	CLIP-seq
MIRT2580666	hsa-miR-548aj	CLIP-seq
MIRT2580667	hsa-miR-548am	CLIP-seq
MIRT2580668	hsa-miR-548x	CLIP-seq
MIRT2580669	hsa-miR-593	CLIP-seq
MIRT2282681	hsa-miR-599	CLIP-seq
MIRT2580670	hsa-miR-612	CLIP-seq
MIRT2580671	hsa-miR-876-3p	CLIP-seq

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	30239752
GO:0005829	Component	Cytosol	IEA
GO:0031093	Component	Platelet alpha granule lumen	TAS

MIM	HGNC	e!Ensembl
618277	24731	ENSG00000196865

Protein

UniProt ID

Q8NBF2

Protein name

NHL repeat-containing protein 2

Protein function

Required for normal embryonic development.

PDB

6G7W , 6GC1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13905	Thioredoxin_8	78 → 174	Thioredoxin-like	Domain
PF01436	NHL	278 → 304	NHL repeat	Repeat
PF01436	NHL	474 → 502	NHL repeat	Repeat
PF01436	NHL	531 → 559	NHL repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Detected in heart, kidney, muscle, brain, lung, liver and in skin fibroblasts (at protein level). {ECO:0000269|PubMed:29423877}.

Sequence

MAAPGGRGRSLSGLLPAQTSLEYALLDAVTQQEKDSLVYQYLQKVDGWEQDLSVPEFPEG
LEWLNTEEPISVYKDLCGKIVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIIGVHS
AKFPNEKVLDNIKSAVLRYNITHPMVNDADASLWQELEVSCWPTLVILGPRGNMLFSLIG
EGHKDKLFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSPLLFPGKVTVDQVTDRLVI
ADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHL
IRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRGDILWIAM
AGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASE
DPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGV
TWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIG
ENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLPKSAPS
IRLSPVTACAGQTLQFKLRLDLPSGSKLTEGVSSCWFLTAEGNEWLLQGQIAAGDIENIS
SQPTISLQIPDDCLSLEAIVSVSVFLYYCSADSSACMMKAILFSQPLQITDTQQGCIAPV
ELRYVF

Sequence length

726

Interactions

View interactions

	Reactome
			Platelet degranulation

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Fibrosis, Neurodegeneration, And Cerebral Angiomatosis	fibrosis, neurodegeneration, and cerebral angiomatosis	rs201701259, rs757267294	N/A

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Hypertension	Hypertension	N/A	N/A	GWAS
Obsessive-Compulsive Disorder	Obsessive-compulsive disorder	N/A	N/A	GWAS

Show/Hide Text Mining Associations (27)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	31402485
Angiomatosis	Associate	30138417
Cerebral Small Vessel Diseases	Stimulate	39826584
Critical Illness	Associate	35801790
Death	Associate	35801790
Depression Postpartum	Associate	35801790
Developmental Disabilities	Associate	37188825
Disease	Associate	30138417
Epilepsy	Associate	37188825
Fibrosis	Associate	30138417, 37188825
Genetic Diseases Inborn	Associate	33948933
Hereditary Myopathy with Early Respiratory Failure	Associate	37188825
Idiopathic Pulmonary Fibrosis	Stimulate	35964085
Immunoglobulin G4 Related Disease	Associate	37188825
Intellectual Disability	Associate	37188825
Lung Diseases Interstitial	Associate	35964085
Mitochondrial complex I deficiency	Associate	35801790
Movement Disorders	Associate	37188825
Multiple Sclerosis	Associate	37559720
Muscle Hypotonia	Associate	37188825
Neurodegenerative Diseases	Associate	30138417
Neurologic Manifestations	Associate	33948933
Neuromuscular Manifestations	Associate	37188825
Respiratory Distress Syndrome	Associate	37188825
Rett Syndrome	Associate	35255187
Seizures	Associate	37188825
Syndrome	Associate	35255187, 35801790, 37188825

NHLRC2 (NHL repeat containing 2)