Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3732
Gene name Gene Name - the full gene name approved by the HGNC.	CD82 molecule
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CD82
Synonyms (NCBI Gene) Gene synonyms aliases	4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a

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miRTarBase ID	miRNA	Experiments	Reference
MIRT054277	hsa-miR-362-3p	Luciferase reporter assay, qRT-PCR, Western blot	25652145
MIRT054277	hsa-miR-362-3p	Luciferase reporter assay, qRT-PCR, Western blot	25652145
MIRT054634	hsa-miR-197-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	24613834
MIRT054634	hsa-miR-197-3p	Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	24613834
MIRT650687	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT650686	hsa-miR-4294	HITS-CLIP	23824327
MIRT650685	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT650684	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT650683	hsa-miR-3672	HITS-CLIP	23824327
MIRT650682	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT650681	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT650680	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT650679	hsa-miR-8055	HITS-CLIP	23824327
MIRT650678	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT054634	hsa-miR-197-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28252644
MIRT054634	hsa-miR-197-3p	Immunofluorescence, Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot	28252644
MIRT650678	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT650679	hsa-miR-8055	HITS-CLIP	27418678
MIRT736194	hsa-miR-633	Luciferase reporter assay, Western blotting, qRT-PCR	33376521
MIRT650687	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT650686	hsa-miR-4294	HITS-CLIP	23824327
MIRT650685	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT650684	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT650683	hsa-miR-3672	HITS-CLIP	23824327
MIRT650682	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT650681	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT650680	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT650679	hsa-miR-8055	HITS-CLIP	23824327
MIRT650678	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT876238	hsa-miR-1193	CLIP-seq
MIRT876239	hsa-miR-122	CLIP-seq
MIRT876240	hsa-miR-197	CLIP-seq
MIRT876241	hsa-miR-1976	CLIP-seq
MIRT876242	hsa-miR-2392	CLIP-seq
MIRT876243	hsa-miR-3135b	CLIP-seq
MIRT876244	hsa-miR-361-3p	CLIP-seq
MIRT876245	hsa-miR-3652	CLIP-seq
MIRT876246	hsa-miR-4258	CLIP-seq
MIRT876247	hsa-miR-4430	CLIP-seq
MIRT876248	hsa-miR-4532	CLIP-seq
MIRT876249	hsa-miR-4662a-5p	CLIP-seq
MIRT876250	hsa-miR-4676-5p	CLIP-seq
MIRT876251	hsa-miR-4707-3p	CLIP-seq
MIRT876252	hsa-miR-4716-5p	CLIP-seq
MIRT876253	hsa-miR-4772-3p	CLIP-seq
MIRT876254	hsa-miR-5096	CLIP-seq
MIRT876255	hsa-miR-513a-3p	CLIP-seq
MIRT876256	hsa-miR-572	CLIP-seq
MIRT876257	hsa-miR-575	CLIP-seq
MIRT876258	hsa-miR-640	CLIP-seq
MIRT876259	hsa-miR-106a	CLIP-seq
MIRT876260	hsa-miR-106b	CLIP-seq
MIRT876238	hsa-miR-1193	CLIP-seq
MIRT876239	hsa-miR-122	CLIP-seq
MIRT876261	hsa-miR-1234	CLIP-seq
MIRT876262	hsa-miR-150	CLIP-seq
MIRT876263	hsa-miR-17	CLIP-seq
MIRT876241	hsa-miR-1976	CLIP-seq
MIRT876264	hsa-miR-20a	CLIP-seq
MIRT876265	hsa-miR-20b	CLIP-seq
MIRT876266	hsa-miR-219-1-3p	CLIP-seq
MIRT876242	hsa-miR-2392	CLIP-seq
MIRT876267	hsa-miR-302a	CLIP-seq
MIRT876268	hsa-miR-302b	CLIP-seq
MIRT876269	hsa-miR-302c	CLIP-seq
MIRT876270	hsa-miR-302d	CLIP-seq
MIRT876271	hsa-miR-302e	CLIP-seq
MIRT876243	hsa-miR-3135b	CLIP-seq
MIRT876244	hsa-miR-361-3p	CLIP-seq
MIRT876245	hsa-miR-3652	CLIP-seq
MIRT876272	hsa-miR-372	CLIP-seq
MIRT876273	hsa-miR-373	CLIP-seq
MIRT876274	hsa-miR-3921	CLIP-seq
MIRT876247	hsa-miR-4430	CLIP-seq
MIRT876275	hsa-miR-4639-5p	CLIP-seq
MIRT876276	hsa-miR-4653-5p	CLIP-seq
MIRT876277	hsa-miR-4682	CLIP-seq
MIRT876278	hsa-miR-4731-5p	CLIP-seq
MIRT876279	hsa-miR-4768-5p	CLIP-seq
MIRT876280	hsa-miR-512-3p	CLIP-seq
MIRT876281	hsa-miR-519d	CLIP-seq
MIRT876282	hsa-miR-520a-3p	CLIP-seq
MIRT876283	hsa-miR-520b	CLIP-seq
MIRT876284	hsa-miR-520c-3p	CLIP-seq
MIRT876285	hsa-miR-520d-3p	CLIP-seq
MIRT876286	hsa-miR-520e	CLIP-seq
MIRT876287	hsa-miR-520g	CLIP-seq
MIRT876288	hsa-miR-520h	CLIP-seq
MIRT876289	hsa-miR-571	CLIP-seq
MIRT876258	hsa-miR-640	CLIP-seq
MIRT876290	hsa-miR-93	CLIP-seq
MIRT876238	hsa-miR-1193	CLIP-seq
MIRT876240	hsa-miR-197	CLIP-seq
MIRT876241	hsa-miR-1976	CLIP-seq
MIRT876242	hsa-miR-2392	CLIP-seq
MIRT1921544	hsa-miR-3149	CLIP-seq
MIRT1921545	hsa-miR-411	CLIP-seq
MIRT876249	hsa-miR-4662a-5p	CLIP-seq
MIRT876250	hsa-miR-4676-5p	CLIP-seq
MIRT876252	hsa-miR-4716-5p	CLIP-seq
MIRT1921546	hsa-miR-483-5p	CLIP-seq
MIRT876254	hsa-miR-5096	CLIP-seq
MIRT876257	hsa-miR-575	CLIP-seq
MIRT876258	hsa-miR-640	CLIP-seq
MIRT876238	hsa-miR-1193	CLIP-seq
MIRT876240	hsa-miR-197	CLIP-seq
MIRT876241	hsa-miR-1976	CLIP-seq
MIRT876242	hsa-miR-2392	CLIP-seq
MIRT1921544	hsa-miR-3149	CLIP-seq
MIRT1921545	hsa-miR-411	CLIP-seq
MIRT876249	hsa-miR-4662a-5p	CLIP-seq
MIRT876250	hsa-miR-4676-5p	CLIP-seq
MIRT876252	hsa-miR-4716-5p	CLIP-seq
MIRT1921546	hsa-miR-483-5p	CLIP-seq
MIRT876254	hsa-miR-5096	CLIP-seq
MIRT876257	hsa-miR-575	CLIP-seq
MIRT876258	hsa-miR-640	CLIP-seq
MIRT876238	hsa-miR-1193	CLIP-seq
MIRT876240	hsa-miR-197	CLIP-seq
MIRT876241	hsa-miR-1976	CLIP-seq
MIRT876242	hsa-miR-2392	CLIP-seq
MIRT1921544	hsa-miR-3149	CLIP-seq
MIRT1921545	hsa-miR-411	CLIP-seq
MIRT876249	hsa-miR-4662a-5p	CLIP-seq
MIRT876250	hsa-miR-4676-5p	CLIP-seq
MIRT876252	hsa-miR-4716-5p	CLIP-seq
MIRT1921546	hsa-miR-483-5p	CLIP-seq
MIRT876254	hsa-miR-5096	CLIP-seq
MIRT876257	hsa-miR-575	CLIP-seq
MIRT876258	hsa-miR-640	CLIP-seq
MIRT876262	hsa-miR-150	CLIP-seq
MIRT1959688	hsa-miR-552	CLIP-seq
MIRT876238	hsa-miR-1193	CLIP-seq
MIRT876239	hsa-miR-122	CLIP-seq
MIRT2196690	hsa-miR-1228	CLIP-seq
MIRT876262	hsa-miR-150	CLIP-seq
MIRT876240	hsa-miR-197	CLIP-seq
MIRT876242	hsa-miR-2392	CLIP-seq
MIRT876243	hsa-miR-3135b	CLIP-seq
MIRT2196691	hsa-miR-3199	CLIP-seq
MIRT876244	hsa-miR-361-3p	CLIP-seq
MIRT2196692	hsa-miR-3616-3p	CLIP-seq
MIRT876245	hsa-miR-3652	CLIP-seq
MIRT2196693	hsa-miR-377	CLIP-seq
MIRT2196694	hsa-miR-3927	CLIP-seq
MIRT1921545	hsa-miR-411	CLIP-seq
MIRT876246	hsa-miR-4258	CLIP-seq
MIRT876247	hsa-miR-4430	CLIP-seq
MIRT2196695	hsa-miR-4436b-3p	CLIP-seq
MIRT876248	hsa-miR-4532	CLIP-seq
MIRT2196696	hsa-miR-4650-3p	CLIP-seq
MIRT876249	hsa-miR-4662a-5p	CLIP-seq
MIRT876250	hsa-miR-4676-5p	CLIP-seq
MIRT2196697	hsa-miR-4690-3p	CLIP-seq
MIRT2196698	hsa-miR-4695-3p	CLIP-seq
MIRT876251	hsa-miR-4707-3p	CLIP-seq
MIRT876252	hsa-miR-4716-5p	CLIP-seq
MIRT2196699	hsa-miR-4721	CLIP-seq
MIRT2196700	hsa-miR-4736	CLIP-seq
MIRT1921546	hsa-miR-483-5p	CLIP-seq
MIRT876254	hsa-miR-5096	CLIP-seq
MIRT876255	hsa-miR-513a-3p	CLIP-seq
MIRT876287	hsa-miR-520g	CLIP-seq
MIRT876288	hsa-miR-520h	CLIP-seq
MIRT1959688	hsa-miR-552	CLIP-seq
MIRT2196701	hsa-miR-562	CLIP-seq
MIRT876257	hsa-miR-575	CLIP-seq
MIRT2196702	hsa-miR-764	CLIP-seq
MIRT876246	hsa-miR-4258	CLIP-seq
MIRT876251	hsa-miR-4707-3p	CLIP-seq
MIRT876255	hsa-miR-513a-3p	CLIP-seq
MIRT876239	hsa-miR-122	CLIP-seq
MIRT876243	hsa-miR-3135b	CLIP-seq
MIRT876244	hsa-miR-361-3p	CLIP-seq
MIRT876245	hsa-miR-3652	CLIP-seq
MIRT876246	hsa-miR-4258	CLIP-seq
MIRT876247	hsa-miR-4430	CLIP-seq
MIRT2196698	hsa-miR-4695-3p	CLIP-seq
MIRT876251	hsa-miR-4707-3p	CLIP-seq
MIRT876255	hsa-miR-513a-3p	CLIP-seq
MIRT876239	hsa-miR-122	CLIP-seq
MIRT876243	hsa-miR-3135b	CLIP-seq
MIRT876244	hsa-miR-361-3p	CLIP-seq
MIRT876245	hsa-miR-3652	CLIP-seq
MIRT876246	hsa-miR-4258	CLIP-seq
MIRT876247	hsa-miR-4430	CLIP-seq
MIRT876251	hsa-miR-4707-3p	CLIP-seq
MIRT876255	hsa-miR-513a-3p	CLIP-seq

Transcription factors

Show/Hide all(6)

Transcription factor	Regulation	Reference
ATF3	Unknown	21454613
HDAC1	Repression	19182791
JUN	Activation	15580298
JUNB	Activation	15580298
TFAP2A	Activation	15580298
TP53	Activation	9736732

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	15205336, 28030805, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	30463011
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	1842498, 7754374
GO:0016020	Component	Membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0045335	Component	Phagocytic vesicle	IEA
GO:0070062	Component	Extracellular exosome	HDA	19199708, 20458337

MIM	HGNC	e!Ensembl
600623	6210	ENSG00000085117

Protein

UniProt ID

P27701

Protein name

CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)

Protein function

Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling (PubMed:19497983). Participates thereby in diverse biological functions su

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00335	Tetraspanin	9 → 255	Tetraspanin family	Family

Tissue specificity

TISSUE SPECIFICITY: Lymphoid specific.

Sequence

MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI
GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI
VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG
EEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAI
IELLGMVLSICLCRHVHSEDYSKVPKY

Sequence length

267

Interactions

View interactions

	KEGG
	p53 signaling pathway

CD82 (CD82 molecule)