Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3727
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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JunD proto-oncogene, AP-1 transcription factor subunit |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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JUND |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AP-1 |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.11 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative transla |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Amyotrophic lateral sclerosis |
Amyotrophic Lateral Sclerosis, Familial |
rs267607084, rs312262720, rs312262752, rs121908287, rs121908288, rs29001584, rs28941475, rs121434378, rs386134173, rs386134174, rs80356730, rs80356727, rs4884357, rs80356717, rs80356733, rs80356731, rs80356726, rs267606928, rs267606929, rs121434591, rs121912431, rs121912432, rs121912433, rs121912434, rs121912435, rs121912440, rs121912436, rs121912437, rs121912438, rs121912439, rs74315452, rs121912442, rs121912443, rs121912444, rs121912446, rs121912447, rs1197141604, rs121912448, rs121912449, rs121912450, rs121912451, rs121912452, rs121912453, rs121912454, rs369600566, rs121912455, rs121912456, rs121912457, rs121912458, rs1555836889, rs121909667, rs121909668, rs121909669, rs121909671, rs121909535, rs121909537, rs121909538, rs121909539, rs121909540, rs121909542, rs121909544, rs80356734, rs367543041, rs80356740, rs80356719, rs80356721, rs80356723, rs80356725, rs387906627, rs387906628, rs387906709, rs387906710, rs387906711, rs387906829, rs387907264, rs387907265, rs387907266, rs312262739, rs312262709, rs312262749, rs200793464, rs147713329, rs312262788, rs397514262, rs63751180, rs587777132, rs730880025, rs730880026, rs730880027, rs368743618, rs730880029, rs730882255, rs730882256, rs786205611, rs121912441, rs199947197, rs780136067, rs772731615, rs879253926, rs879254294, rs764717219, rs886041390, rs750159428, rs753207473, rs267607087, rs767350733, rs778305085, rs1554707680, rs1554707622, rs1393363759, rs750959420, rs1555509569, rs1554716504, rs11556620, rs1247392012, rs142083484, rs140385286, rs371575563, rs1402429085, rs1555179091, rs1555179087, rs746971952, rs1555836950, rs368276916, rs140376902, rs747220413, rs76731700, rs770684782, rs1200906022, rs1804449, rs1482760341, rs769898852, rs140599944, rs757972700, rs1555451521, rs1592362719, rs1555836803, rs763455928, rs1378590183, rs1583695322, rs1362178149, rs1197928094, rs368751524, rs1555509609, rs1574787779, rs1601157750, rs1301635320, rs1341055534, rs1402092579, rs1568809172, rs1555836170, rs1315541036, rs1339283341, rs1643659556, rs1644506661, rs1435710212, rs1553122918, rs1689580631, rs374047961, rs775935265, rs2076486420, rs1820836522, rs757260058, rs1844420892, rs1833371664, rs1833438306, rs1833451208, rs2083790483, rs1303294230, rs1226110412, rs2053207945, rs2053208751, rs2053501632, rs2053539304, rs1567479067, rs544088874, rs1228194239, rs1568807400, rs1169198442, rs2049594204, rs2049594311, rs1568810641, rs1568811372, rs2049618449, rs1476760624, rs2079347087 View all (171 more) |
11796754 |
Glomerulonephritis |
Glomerulonephritis |
rs778043831 |
18443593 |
Lateral sclerosis |
AMYOTROPHIC LATERAL SCLEROSIS 1, Amyotrophic Lateral Sclerosis, Sporadic |
rs386134181, rs386134176, rs386134174, rs386134184, rs386134178, rs1693780539, rs1574698048 |
11796754 |
Lung cancer |
Malignant neoplasm of lung |
rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 |
27935865 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Systemic lupus erythematosus |
Systemic lupus erythematosus |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Alzheimer Disease |
Associate
|
37933012 |
Arthritis Rheumatoid |
Associate
|
23072510 |
Breast Neoplasms |
Associate
|
17166846, 21393445, 22988241, 28212576, 30337371 |
Cachexia |
Inhibit
|
19470832 |
Carcinogenesis |
Associate
|
23496845, 25332240 |
Carcinoid Tumor |
Associate
|
18655788 |
Carcinoma Hepatocellular |
Associate
|
18644981, 24659263, 25522777, 30382079 |
Carcinoma Pancreatic Ductal |
Associate
|
36889906 |
Carcinoma Squamous Cell |
Associate
|
11792626 |
Cholangiocarcinoma |
Associate
|
36400758 |
Colorectal Neoplasms |
Associate
|
24151146, 26625825, 33413550, 35697349 |
COVID 19 |
Associate
|
34312772 |
Death |
Associate
|
23376981 |
Diabetes Mellitus |
Associate
|
34801581 |
Diabetic Cardiomyopathies |
Associate
|
34801581 |
Down Syndrome |
Associate
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16100769, 30763715 |
Dystonic Disorders |
Associate
|
35941657 |
Glioblastoma |
Associate
|
19276385, 27076368 |
Hypoxia |
Stimulate
|
10487833 |
Hypoxia Brain |
Stimulate
|
8065332 |
Inflammation |
Associate
|
23072510, 36986236 |
Leukemia |
Associate
|
10845928 |
Leukemia Hairy Cell |
Associate
|
12576324 |
Leukemia Lymphoma Adult T Cell |
Associate
|
10845928, 18078517, 23482931 |
Leukemia Myelogenous Chronic BCR ABL Positive |
Associate
|
7649976 |
Leukemia Myeloid Acute |
Associate
|
12082101 |
Lung Neoplasms |
Associate
|
10823417, 27184257, 37894738 |
Lymphoma B Cell Marginal Zone |
Associate
|
15507668 |
Lymphoma Large B Cell Diffuse |
Stimulate
|
26747248 |
Lymphoma T Cell Cutaneous |
Associate
|
9864169 |
Melanoma |
Associate
|
14717848, 35926467 |
Mouth Neoplasms |
Associate
|
23324604, 28155253 |
Multiple Endocrine Neoplasia Type 1 |
Associate
|
23376981 |
Multiple Myeloma |
Associate
|
12969976 |
Muscular Atrophy |
Associate
|
19470832 |
Nasopharyngeal Carcinoma |
Associate
|
23496845 |
Necrosis |
Stimulate
|
27076368 |
Neoplasm Metastasis |
Associate
|
36400758 |
Neoplasms |
Associate
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16265353, 18655788, 19602461, 19758438, 21734453, 22853846, 23772146, 24073962, 24659263, 26832411, 28155253, 31766230, 39342037 |
Neurodegenerative Diseases |
Associate
|
34312772 |
Osteoarthritis |
Associate
|
30081074 |
Pancreatic Neoplasms |
Stimulate
|
17912030 |
Pancreatic Neoplasms |
Associate
|
19435822, 36889906 |
Prostatic Neoplasms |
Associate
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20460526, 21622724, 21734453, 24647988, 26732163, 27358408, 30763715 |
Prostatitis |
Associate
|
30763715 |
Renal Insufficiency Chronic |
Associate
|
37933012 |
Scleroderma Systemic |
Associate
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32977850 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
22853846 |
Stomach Neoplasms |
Associate
|
1331059 |
Urinary Bladder Neoplasms |
Associate
|
31906413 |
Uterine Cervical Neoplasms |
Associate
|
21937452 |
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